Homo sapiens (human): 81794
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Entry
81794 CDS
T01001
Symbol
ADAMTS10, ADAM-TS10, ADAMTS-10, WMS, WMS1
Name
(RefSeq) ADAM metallopeptidase with thrombospondin type 1 motif 10
KO
K08625
a disintegrin and metalloproteinase with thrombospondin motifs 10 [EC:3.4.24.-]
Organism
hsa
Homo sapiens (human)
Disease
H00673
Weill-Marchesani syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
81794 (ADAMTS10)
Peptidases and inhibitors [BR:
hsa01002
]
Metallo peptidases
Family M12: astacin/adamalysin family
81794 (ADAMTS10)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TSP1_ADAMTS
Reprolysin
ADAMTS_spacer1
ADAMTS_CR_2
TSP_1
Pep_M12B_propep
Reprolysin_5
Reprolysin_3
ADAMTS_CR_3
Reprolysin_2
PLAC
Reprolysin_4
TSP1_CCN
TSP1_spondin
DUF4953
DAGK_cat
Motif
Other DBs
NCBI-GeneID:
81794
NCBI-ProteinID:
NP_112219
OMIM:
608990
HGNC:
13201
Ensembl:
ENSG00000142303
UniProt:
Q9H324
A0A0A0MQW6
Q59FE5
Q6ZN14
LinkDB
All DBs
Position
19:complement(8580240..8610715)
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AA seq
1103 aa
AA seq
DB search
MAPACQILRWALALGLGLMFEVTHAFRSQDEFLSSLESYEIAFPTRVDHNGALLAFSPPP
PRRQRRGTGATAESRLFYKVASPSTHFLLNLTRSSRLLAGHVSVEYWTREGLAWQRAARP
HCLYAGHLQGQASSSHVAISTCGGLHGLIVADEEEYLIEPLHGGPKGSRSPEESGPHVVY
KRSSLRHPHLDTACGVRDEKPWKGRPWWLRTLKPPPARPLGNETERGQPGLKRSVSRERY
VETLVVADKMMVAYHGRRDVEQYVLAIMNIVAKLFQDSSLGSTVNILVTRLILLTEDQPT
LEITHHAGKSLDSFCKWQKSIVNHSGHGNAIPENGVANHDTAVLITRYDICIYKNKPCGT
LGLAPVGGMCERERSCSVNEDIGLATAFTIAHEIGHTFGMNHDGVGNSCGARGQDPAKLM
AAHITMKTNPFVWSSCSRDYITSFLDSGLGLCLNNRPPRQDFVYPTVAPGQAYDADEQCR
FQHGVKSRQCKYGEVCSELWCLSKSNRCITNSIPAAEGTLCQTHTIDKGWCYKRVCVPFG
SRPEGVDGAWGPWTPWGDCSRTCGGGVSSSSRHCDSPRPTIGGKYCLGERRRHRSCNTDD
CPPGSQDFREVQCSEFDSIPFRGKFYKWKTYRGGGVKACSLTCLAEGFNFYTERAAAVVD
GTPCRPDTVDICVSGECKHVGCDRVLGSDLREDKCRVCGGDGSACETIEGVFSPASPGAG
YEDVVWIPKGSVHIFIQDLNLSLSHLALKGDQESLLLEGLPGTPQPHRLPLAGTTFQLRQ
GPDQVQSLEALGPINASLIVMVLARTELPALRYRFNAPIARDSLPPYSWHYAPWTKCSAQ
CAGGSQVQAVECRNQLDSSAVAPHYCSAHSKLPKRQRACNTEPCPPDWVVGNWSLCSRSC
DAGVRSRSVVCQRRVSAAEEKALDDSACPQPRPPVLEACHGPTCPPEWAALDWSECTPSC
GPGLRHRVVLCKSADHRATLPPAHCSPAAKPPATMRCNLRRCPPARWVAGEWGECSAQCG
VGQRQRSVRCTSHTGQASHECTEALRPPTTQQCEAKCDSPTPGDGPEECKDVNKVAYCPL
VLKFQFCSRAYFRQMCCKTCHGH
NT seq
3312 nt
NT seq
+upstream
nt +downstream
nt
atggctcccgcctgccagatcctccgctgggccctcgccctggggctgggcctcatgttc
gaggtcacgcacgccttccggtctcaagatgagttcctgtccagtctggagagctatgag
atcgccttccccacccgcgtggaccacaacggggcactgctggccttctcgccacctcct
ccccggaggcagcgccgcggcacgggggccacagccgagtcccgcctcttctacaaagtg
gcctcgcccagcacccacttcctgctgaacctgacccgcagctcccgtctactggcaggg
cacgtctccgtggagtactggacacgggagggcctggcctggcagagggcggcccggccc
cactgcctctacgctggtcacctgcagggccaggccagcagctcccatgtggccatcagc
acctgtggaggcctgcacggcctgatcgtggcagacgaggaagagtacctgattgagccc
ctgcacggtgggcccaagggttctcggagcccggaggaaagtggaccacatgtggtgtac
aagcgttcctctctgcgtcacccccacctggacacagcctgtggagtgagagatgagaaa
ccgtggaaagggcggccatggtggctgcggaccttgaagccaccgcctgccaggcccctg
gggaatgaaacagagcgtggccagccaggcctgaagcgatcggtcagccgagagcgctac
gtggagaccctggtggtggctgacaagatgatggtggcctatcacgggcgccgggatgtg
gagcagtatgtcctggccatcatgaacattgttgccaaacttttccaggactcgagtctg
ggaagcaccgttaacatcctcgtaactcgcctcatcctgctcacggaggaccagcccact
ctggagatcacccaccatgccgggaagtccctggacagcttctgtaagtggcagaaatcc
atcgtgaaccacagcggccatggcaatgccattccagagaacggtgtggctaaccatgac
acagcagtgctcatcacacgctatgacatctgcatctacaagaacaaaccctgcggcaca
ctaggcctggccccggtgggcggaatgtgtgagcgcgagagaagctgcagcgtcaatgag
gacattggcctggccacagcgttcaccattgcccacgagatcgggcacacattcggcatg
aaccatgacggcgtgggaaacagctgtggggcccgtggtcaggacccagccaagctcatg
gctgcccacattaccatgaagaccaacccattcgtgtggtcatcctgcagccgtgactac
atcaccagctttctagactcgggcctggggctctgcctgaacaaccggccccccagacag
gactttgtgtacccgacagtggcaccgggccaagcctacgatgcagatgagcaatgccgc
tttcagcatggagtcaaatcgcgtcagtgtaaatacggggaggtctgcagcgagctgtgg
tgtctgagcaagagcaaccggtgcatcaccaacagcatcccggccgccgagggcacgctg
tgccagacgcacaccatcgacaaggggtggtgctacaaacgggtctgtgtcccctttggg
tcgcgcccagagggtgtggacggagcctgggggccgtggactccatggggcgactgcagc
cggacctgtggcggcggcgtgtcctcttctagccgtcactgcgacagccccaggccaacc
atcgggggcaagtactgtctgggtgagagaaggcggcaccgctcctgcaacacggatgac
tgtccccctggctcccaggacttcagagaagtgcagtgttctgaatttgacagcatccct
ttccgtgggaaattctacaagtggaaaacgtaccggggagggggcgtgaaggcctgctcg
ctcacgtgcctagcggaaggcttcaacttctacacggagagggcggcagccgtggtggac
gggacaccctgccgtccagacacggtggacatttgcgtcagtggcgaatgcaagcacgtg
ggctgcgaccgagtcctgggctccgacctgcgggaggacaagtgccgagtgtgtggcggt
gacggcagtgcctgcgagaccatcgagggcgtcttcagcccagcctcacctggggccggg
tacgaggatgtcgtctggattcccaaaggctccgtccacatcttcatccaggatctgaac
ctctctctcagtcacttggccctgaagggagaccaggagtccctgctgctggaggggctg
cctgggaccccccagccccaccgtctgcctctagctgggaccacctttcaactgcgacag
gggccagaccaggtccagagcctcgaagccctgggaccgattaatgcatctctcatcgtc
atggtgctggcccggaccgagctgcctgccctccgctaccgcttcaatgcccccatcgcc
cgtgactcgctgcccccctactcctggcactatgcgccctggaccaagtgctcggcccag
tgtgcaggcggtagccaggtgcaggcggtggagtgccgcaaccagctggacagctccgcg
gtcgccccccactactgcagtgcccacagcaagctgcccaaaaggcagcgcgcctgcaac
acggagccttgccctccagactgggttgtagggaactggtcgctctgcagccgcagctgc
gatgcaggcgtgcgcagccgctcggtcgtgtgccagcgccgcgtctctgccgcggaggag
aaggcgctggacgacagcgcatgcccgcagccgcgcccacctgtactggaggcctgccac
ggccccacttgccctccggagtgggcggccctcgactggtctgagtgcacccccagctgc
gggccgggcctccgccaccgcgtggtcctttgcaagagcgcagaccaccgcgccacgctg
cccccggcgcactgctcacccgccgccaagccaccggccaccatgcgctgcaacttgcgc
cgctgccccccggcccgctgggtggctggcgagtggggtgagtgctctgcacagtgcggc
gtcgggcagcggcagcgctcggtgcgctgcaccagccacacgggccaggcgtcgcacgag
tgcacggaggccctgcggccgcccaccacgcagcagtgtgaggccaagtgcgacagccca
acccccggggacggccctgaagagtgcaaggatgtgaacaaggtcgcctactgccccctg
gtgctcaaatttcagttctgcagccgagcctacttccgccagatgtgctgcaaaacctgc
catggccactag
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