Homo sapiens (human): 8273
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Entry
8273 CDS
T01001
Symbol
SLC10A3, DXS253E, P3
Name
(RefSeq) solute carrier family 10 member 3
KO
K14343
solute carrier family 10 (sodium/bile acid cotransporter), member 3/5
Organism
hsa
Homo sapiens (human)
Drug target
Maralixibat (
DG02832
):
D10951
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
hsa02000
]
8273 (SLC10A3)
Transporters [BR:
hsa02000
]
Solute carrier family (SLC)
SLC10: Sodium bile salt cotransporter
8273 (SLC10A3)
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Gene cluster
GFIT
Motif
Pfam:
SBF
NTCP5_P3_N
Motif
Other DBs
NCBI-GeneID:
8273
NCBI-ProteinID:
NP_001135864
OMIM:
312090
HGNC:
22979
Ensembl:
ENSG00000126903
UniProt:
P09131
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Position
X:complement(154487311..154490629)
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AA seq
477 aa
AA seq
DB search
MVLMQDKGSSQQWPGLGGEGGGTGPLSMLRAALLLISLPWGAQGTASTSLSTAGGHTVPP
TGGRYLSIGDGSVMEFEFPEDSEGIIVISSQYPGQANRTAPGPMLRVTSLDTEVLTIKNV
SAITWGGGGGFVVSIHSGLAGLAPLHIQLVDAHEAPPTLIEERRDFCIKVSPAEDTPATL
SADLAHFSENPILYLLLPLIFVNKCSFGCKVELEVLKGLMQSPQPMLLGLLGQFLVMPLY
AFLMAKVFMLPKALALGLIITCSSPGGGGSYLFSLLLGGDVTLAISMTFLSTVAATGFLP
LSSAIYSRLLSIHETLHVPISKILGTLLFIAIPIAVGVLIKSKLPKFSQLLLQVVKPFSF
VLLLGGLFLAYRMGVFILAGIRLPIVLVGITVPLVGLLVGYCLATCLKLPVAQRRTVSIE
VGVQNSLLALAMLQLSLRRLQADYASQAPFIVALSGTSEMLALVIGHFIYSSLFPVP
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
atggtgttaatgcaggacaagggcagctctcagcagtggcctggtctggggggcgagggt
ggtggcacaggtcccttaagcatgctcagagctgccctgctgctcatcagcctgccatgg
ggggcccaagggacagccagcaccagcctcagcactgctgggggtcacaccgtgccaccg
actgggggccgctacttgagcattggagatggctctgtgatggagtttgagtttcctgag
gacagtgagggcatcatcgtgatctccagccagtacccaggccaggccaacaggacggcg
cctggccccatgctcagggtcacctccctggacacagaggtgctgaccatcaagaacgtg
agtgctataacctggggaggcgggggtggctttgtggtgagcatccactcaggcctggct
gggctggccccactccacatccagctcgtggacgcccatgaggccccgcccacactgatt
gaggagcggagagacttctgcatcaaggtctcacctgctgaagacacgcctgccaccctc
agcgccgacctggcccacttctcggaaaacccaatcctctacctgctcctgcctcttatc
tttgtcaacaagtgttcgtttgggtgcaaagtggaactcgaggttctgaaggggctcatg
cagagcccccagcccatgctgctgggcctcctgggccagtttctggtcatgcccttgtac
gctttcctcatggccaaggtcttcatgctgcccaaggccctggctctgggcctcatcatc
acctgctcgtcgcctggcggcggggggagctacctcttcagcctccttcttggaggggac
gtcaccctggccatctccatgactttcctctctacggtggctgccactggcttcttgcct
ctgtcttcggccatctacagccgcctgctcagcatccatgagacgctccacgtgcccatc
tccaagatcctggggaccctgctgttcattgccatccccatagccgtgggcgtgctgatc
aagtccaagctccccaagttctcccagctgctgctgcaggtcgtcaagcccttcagcttt
gtgctcctcctgggcggcctcttcctggcctatcgcatgggggtcttcatcctggcaggc
atccggctacccatcgtactggtgggtatcacggtgcccctggttggcctgttggtgggc
tactgcctagccacgtgtctgaagctgccagtggcccagcggcggacggtcagcattgag
gtaggggtgcagaacagcctgctggccttggccatgctgcagctatccctccgccgcctt
caagctgactatgcctcccaggcccccttcattgtggcgctgagcggcacctccgagatg
ctggccttggtcattggccacttcatctacagcagcctgttcccagttccctga
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