Homo sapiens (human): 8287
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Entry
8287 CDS
T01001
Symbol
USP9Y, DFFRY, FAF-Y, SPGFY2
Name
(RefSeq) ubiquitin specific peptidase 9 Y-linked
KO
K11840
ubiquitin carboxyl-terminal hydrolase 9/24 [EC:
3.4.19.12
]
Organism
hsa
Homo sapiens (human)
Disease
H00890
Azoospermia
H02534
Y-linked spermatogenic failure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
hsa01002
]
8287 (USP9Y)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
8287 (USP9Y)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.19 Omega peptidases
3.4.19.12 ubiquitinyl hydrolase 1
8287 (USP9Y)
Peptidases and inhibitors [BR:
hsa01002
]
Cysteine peptidases
Family C19: ubiquitin-specific protease family
8287 (USP9Y)
Ubiquitin system [BR:
hsa04121
]
Deubiquitinating enzyme (DUB)
Ubiquitin-specific proteases (UBPs)
UBP/USP
8287 (USP9Y)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ARM_UBP24_USP9X-Y
DUF3517
UCH
UCH_UBL1
UCH_1
Dsc3_N
Motif
Other DBs
NCBI-GeneID:
8287
NCBI-ProteinID:
NP_004645
OMIM:
400005
HGNC:
12633
Ensembl:
ENSG00000114374
UniProt:
O00507
LinkDB
All DBs
Position
Y:12701231..12860839
Genome browser
AA seq
2555 aa
AA seq
DB search
MTAITHGSPVGGNDSQGQVLDGQSQHLFQQNQTSSPDSSNENSVATPPPEEQGQGDAPPQ
HEDEEPAFPHTELANLDDMINRPRWVVPVLPKGELEVLLEAAIDLSVKGLDVKSEACQRF
FRDGLTISFTKILMDEAVSGWKFEIHRCIINNTHRLVELCVAKLSQDWFPLLELLAMALN
PHCKFHIYNGTRPCELISSNAQLPEDELFARSSDPRSPKGWLVDLINKFGTLNGFQILHD
RFFNGSALNIQIIAALIKPFGQCYEFLSQHTLKKYFIPVIEIVPHLLENLTDEELKKEAK
NEAKNDALSMIIKSLKNLASRISGQDETIKNLEIFRLKMILRLLQISSFNGKMNALNEIN
KVISSVSYYTHRHSNPEEEEWLTAERMAEWIQQNNILSIVLQDSLHQPQYVEKLEKILRF
VIKEKALTLQDLDNIWAAQAGKHEAIVKNVHDLLAKLAWDFSPGQLDHLFDCFKASWTNA
SKKQREKLLELIRRLAEDDKDGVMAHKVLNLLWNLAQSDDVPVDIMDLALSAHIKILDYS
CSQDRDAQKIQWIDHFIEELRTNDKWVIPALKQIREICSLFGEASQNLSQTQRSPHIFYR
HDLINQLQQNHALVTLVAENLATYMNSIRLYAGDHEDYDPQTVRLGSRYSHVQEVQERLN
FLRFLLKDGQLWLCAPQAKQIWKCLAENAVYLCDREACFKWYSKLMGDEPDLDPDINKDF
FESNVLQLDPSLLTENGMKCFERFFKAVNCRERKLIAKRRSYMMDDLELIGLDYLWRVVI
QSSDEIANRAIDLLKEIYTNLGPRLKANQVVIHEDFIQSCFDRLKASYDTLCVFDGDKNS
INCARQEAIRMVRVLTVIKEYINECDSDYHKERMILPMSRAFRGKHLSLIVRFPNQGRQV
DELDIWSHTNDTIGSVRRCIVNRIKANVAHKKIELFVGGELIDSEDDRKLIGQLNLKDKS
LITAKLTQINFNMPSSPDSSSDSSTASPGNHRNHYNDGPNLEVESCLPGVIMSVHPRYIS
FLWQVADLGSNLNMPPLRDGARVLMKLMPPDRTAVEKLRAVCLDHAKLGEGKLSPPLDSL
FFGPSASQVLYLTEVVYALLMPAGVPLTDGSSDFQVHFLKSGGLPLVLSMLIRNNFLPNT
DMETRRGAYLNALKIAKLLLTAIGYGHVRAVAEACQPVVDGTDPITQINQVTHDQAVVLQ
SALQSIPNPSSECVLRNESILLAQEISNEASRYMPDICVIRAIQKIIWASACGALGLVFS
PNEEITKIYQMTTNGSNKLEVEDEQVCCEALEVMTLCFALLPTALDALSKEKAWQTFIID
LLLHCPSKTVRQLAQEQFFLMCTRCCMGHRPLLFFITLLFTILGSTAREKGKYSGDYFTL
LRHLLNYAYNGNINIPNAEVLLVSEIDWLKRIRDNVKNTGETGVEEPILEGHLGVTKELL
AFQTSEKKYHFGCEKGGANLIKELIDDFIFPASKVYLQYLRSGELPAEQAIPVCSSPVTI
NAGFELLVALAIGCVRNLKQIVDCLTEMYYMGTAITTCEALTEWEYLPPVGPRPPKGFVG
LKNAGATCYMNSVIQQLYMIPSIRNSILAIEGTGSDLHDDMFGDEKQDSESNVDPRDDVF
GYPHQFEDKPALSKTEDRKEYNIGVLRHLQVIFGHLAASQLQYYVPRGFWKQFRLWGEPV
NLREQHDALEFFNSLVDSLDEALKALGHPAILSKVLGGSFADQKICQGCPHRYECEESFT
TLNVDIRNHQNLLDSLEQYIKGDLLEGANAYHCEKCDKKVDTVKRLLIKKLPRVLAIQLK
RFDYDWERECAIKFNDYFEFPRELDMGPYTVAGVANLERDNVNSENELIEQKEQSDNETA
GGTKYRLVGVLVHSGQASGGHYYSYIIQRNGKDDQTDHWYKFDDGDVTECKMDDDEEMKN
QCFGGEYMGEVFDHMMKRMSYRRQKRWWNAYILFYEQMDMIDEDDEMIRYISELTIARPH
QIIMSPAIERSVRKQNVKFMHNRLQYSLEYFQFVKKLLTCNGVYLNPAPGQDYLLPEAEE
ITMISIQLAARFLFTTGFHTKKIVRGPASDWYDALCVLLRHSKNVRFWFTHNVLFNVSNR
FSEYLLECPSAEVRGAFAKLIVFIAHFSLQDGSCPSPFASPGPSSQACDNLSLSDHLLRA
TLNLLRREVSEHGHHLQQYFNLFVMYANLGVAEKTQLLKLNVPATFMLVSLDEGPGPPIK
YQYAELGKLYSVVSQLIRCCNVSSTMQSSINGNPPLPNPFGDLNLSQPIMPIQQNVLDIL
FVRTSYVKKIIEDCSNSEDTIKLLRFCSWENPQFSSTVLSELLWQVAYSYTYELRPYLDL
LFQILLIEDSWQTHRIHNALKGIPDDRDGLFDTIQRSKNHYQKRAYQCIKCMVALFSSCP
VAYQILQGNGDLKRKWTWAVEWLGDELERRPYTGNPQYSYNNWSPPVQSNETANGYFLER
SHSARMTLAKACELCPEEEPDDQDAPDEHEPSPSEDAPLYPHSPASQYQQNNHVHGQPYT
GPAAHHLNNPQKTGQRTQENYEGNEEVSSPQMKDQ
NT seq
7668 nt
NT seq
+upstream
nt +downstream
nt
atgacagccatcactcatggctctccagtaggagggaacgacagccagggccaggttctt
gatggccagtctcagcatctcttccaacagaaccagacttcatcacctgattcttccaat
gagaattccgtagcaactcctcctccagaggaacaagggcaaggtgatgccccaccacag
catgaagatgaagagcctgcatttccacatactgagctggcaaacctggatgacatgatc
aacaggcctcgatgggtggttcctgttttgccaaaaggggaattagaagtgcttttagaa
gctgctattgatcttagtgtaaaaggccttgatgttaaaagtgaagcatgccaacgtttt
tttcgagatggactaacaatatctttcactaaaattcttatggatgaggctgtgagtggc
tggaagtttgaaattcatagatgtattattaacaatactcatcgcctagtggagctttgt
gtggccaagttgtcccaagattggtttccacttctagaacttctcgccatggccttaaat
cctcactgcaagtttcatatctacaatggtacacgtccgtgtgaattaatttcctcaaat
gctcagttgcctgaagatgaattatttgctcgttcttcagatcctcgatcaccaaaaggt
tggctagtggatctcatcaataaatttggcacattaaatgggttccagattttgcatgat
cgtttttttaatggatcagcattaaatattcaaataattgcagctcttattaaaccattt
ggacaatgctatgagtttctcagtcaacatacactgaaaaagtacttcattccagttata
gaaatagttccacatttattggaaaacttaactgatgaagaactgaaaaaggaggcaaag
aatgaagccaaaaatgatgccctttcaatgattattaaatctttgaagaacttagcttca
agaatttcaggacaagatgagactataaaaaatttggaaatttttaggttaaagatgata
ctcagattgttgcaaatttcctcttttaatggaaagatgaatgcactgaatgaaataaat
aaggttatatctagtgtatcatattatactcatcggcatagtaatcctgaggaggaagaa
tggctgacagctgagcgaatggcagaatggatacagcaaaataatatcttatccatagtc
ttgcaagacagtcttcatcaaccacaatatgtagaaaagctagagaaaattcttcgtttt
gtgattaaagaaaaggctcttacattacaggaccttgataatatctgggcagcacaggca
ggaaaacatgaagccattgtgaagaatgtacatgatctgctagcaaagttggcttgggat
ttttctcctggacaacttgatcatctttttgattgctttaaggcaagttggacaaatgca
agtaaaaagcaacgtgaaaagctccttgagttgatacgccgtcttgcagaagatgataaa
gatggtgtgatggcacacaaagtgttgaaccttctttggaacctggctcagagtgatgat
gtgcctgtagacatcatggaccttgctcttagtgcccacataaaaatactagattatagt
tgttcccaggatcgagatgcacagaagatccagtggatagatcactttatagaagaactt
cgcacaaatgacaagtgggtaattcctgctctgaaacaaataagagaaatttgtagtttg
tttggtgaagcatctcaaaatttgagtcaaactcagcgaagtccccacatattttatcgc
catgatttaatcaaccagcttcaacaaaatcatgctttagttactttggtagcagaaaac
cttgcaacctacatgaatagcatcagattgtatgctggagatcatgaagactatgatcca
caaacagtgaggcttggaagtcgatacagtcatgttcaagaagttcaagaacgactaaac
ttccttagatttttactgaaggatggccaactgtggctctgtgctcctcaggcaaaacaa
atatggaagtgcttagcagaaaatgcagtttatctttgtgatcgtgaagcctgttttaag
tggtattccaagttaatgggggatgaaccagacttggatcctgatattaataaggacttc
tttgaaagtaatgtacttcagcttgatccttcccttttaactgaaaatggaatgaaatgc
tttgaaagatttttcaaagctgtcaattgtcgagaaaggaaactaatagcaaaaagaaga
tcctatatgatggatgatttggaattaattggactagactacctttggagggttgtgatt
cagagtagtgacgagattgctaacagagctatagatcttcttaaagagatatacacaaac
cttggcccaagattaaaagccaatcaggtggttatccatgaagacttcattcagtcttgc
tttgatcgtttaaaagcatcatatgatacactgtgtgtttttgatggtgacaaaaacagc
attaattgtgcaagacaagaagccattcgaatggttagagtattaactgttataaaagag
tacattaatgaatgtgacagtgattatcacaaggaaagaatgattctacctatgtcgaga
gcatttcgtggcaaacacctctctcttatagttcggtttccaaaccagggcagacaggtt
gatgagttggatatatggtctcatacgaatgacacaattggttcagtacggcgatgtatt
gttaatcgtattaaagccaatgtagcccacaaaaaaattgaactttttgtgggtggtgag
ctgatagattctgaagatgacagaaagctaattggacaattaaacttaaaagataaatct
ctaattacagccaaacttacacaaataaatttcaatatgccatcaagtcctgatagctct
tccgattcctcaactgcatctcctggaaaccaccgtaatcattacaatgatggtcccaat
ctagaggtggaaagttgtttgcctggggtgataatgtcagtgcatcccagatacatctct
ttcctttggcaagttgcagacttaggtagcaacctgaatatgccacctcttagagatgga
gcaagagtacttatgaaacttatgccaccagatagaacagctgtagaaaaattacgagct
gtttgtttggaccatgcaaaacttggagaaggcaaacttagtccaccccttgactctctt
ttctttggtccttctgcctcccaagttctatacctaacagaggtagtttatgccttgtta
atgcctgctggtgtgcctctaactgatgggtcctctgactttcaagttcacttcttgaaa
agtggtggcttacctcttgtactgagtatgctaataagaaataacttcttgccaaataca
gatatggaaactcgaaggggtgcttatttaaatgctcttaaaatagccaaactgttgtta
actgcgattggctatggccatgttcgagctgtagcagaagcttgtcagccagttgtagat
ggtacagaccccataacacagattaaccaagttactcatgatcaagcagtggtgctacaa
agtgcccttcagagcattcctaatccctcatccgagtgcgtacttagaaatgagtccata
cttcttgctcaggaaatatctaatgaggcttcaagatatatgcctgatatttgtgtaatt
agggctatacagaaaattatctgggcatcagcatgtggggcattaggactagtttttagc
ccaaatgaagaaataactaaaatttatcagatgaccaccaatggaagcaataagctggag
gtggaagatgaacaagtttgctgtgaagcactggaagtgatgaccttatgttttgcttta
cttccaacagcgttggatgcacttagtaaagaaaaagcctggcagaccttcatcattgac
ttattattgcactgtccaagcaaaactgttcgtcagttggcacaggagcagttcttttta
atgtgcaccagatgttgcatgggacacaggcctctgcttttcttcattactttactcttt
accatactggggagcacagcaagagagaagggtaaatattcaggtgattatttcacactt
ttacggcaccttctcaattatgcttacaatggcaatattaacatacccaatgctgaagtt
cttcttgtcagtgaaattgattggctcaaaaggattagggataatgttaaaaacacaggt
gaaacaggtgtcgaagagccaatactggaaggccaccttggggtaacaaaagagttattg
gcctttcaaacttctgagaaaaagtatcactttggttgtgaaaaaggaggtgctaatctc
attaaagaattaattgatgatttcatctttcccgcatccaaagtttacctgcagtattta
agaagtggagaactaccagctgagcaggctattccagtctgtagttcacccgttaccatc
aatgccggttttgagctacttgtagcattagctattggctgtgtgaggaatctcaaacag
atagtagactgtttgactgaaatgtattacatgggcacagcaattactacttgtgaagca
cttactgagtgggaatatctgccccctgttggaccccgcccaccaaaaggatttgtggga
ctcaaaaatgctggtgctacgtgttacatgaactctgtgatccagcagctatacatgatt
ccttctatcaggaacagtattcttgcaattgaaggcacaggtagtgatttacacgatgat
atgttcggggatgagaagcaggacagtgagagtaatgttgatccccgagatgatgtattt
ggatatcctcatcaatttgaagacaagccagcattaagtaagacagaagataggaaagag
tataatattggtgtcctaagacaccttcaggtcatctttggtcatttagctgcttcccaa
ctacaatactatgtacccagaggattttggaaacagttcaggctttggggtgaacctgtt
aatctccgtgaacaacatgatgccttagagttttttaattctttggtggatagtttagat
gaagctttaaaagctttaggacacccggctatactaagtaaagtcctaggaggctccttt
gctgatcagaagatctgccaaggctgcccacataggtatgaatgtgaagaatcttttaca
actttgaatgtggatattagaaatcatcaaaatcttcttgactctttggaacagtatatc
aaaggagatttattggaaggtgcaaatgcatatcattgtgaaaaatgtgataaaaaggtt
gacacagtaaagcgcctgctaattaaaaaattgcctcgggttcttgctatccaactcaaa
cgatttgactatgactgggaaagagaatgtgcaattaaattcaatgattattttgaattt
cctcgagagctggatatgggaccttacacagtagcaggtgttgcaaacctggaaagggat
aatgtaaactcagaaaatgagttgattgaacagaaagagcagtctgacaatgaaactgca
ggaggcacaaagtacagacttgtaggagtgcttgtacacagtggtcaagcaagcggtggg
cattattattcttacatcattcaaaggaatggtaaagatgatcagacagatcactggtat
aaatttgatgatggagatgtaacagaatgcaaaatggatgatgatgaagaaatgaaaaat
cagtgttttggtggagagtacatgggagaagtatttgatcacatgatgaagcgcatgtca
tataggcgacagaagaggtggtggaatgcttacatacttttttatgaacaaatggatatg
atagatgaagatgatgagatgataagatacatatcagagctaactattgcaagaccccat
cagatcattatgtcaccagccattgagagaagtgtacggaaacaaaatgtgaaatttatg
cataaccgattgcaatatagtttagagtattttcagtttgtgaaaaaactgcttacatgt
aatggtgtttatttaaaccctgctccagggcaggattatttgttgcctgaagcagaagaa
attactatgattagtattcagcttgctgctagattcctctttaccactggatttcacacc
aagaaaatagttcgtggtcctgccagtgactggtatgatgcactgtgcgttcttctccgt
cacagcaaaaatgtacgtttttggtttactcataatgtcctttttaatgtatcaaatcgc
ttctctgaataccttctggagtgccctagtgcagaagtgaggggtgcatttgcaaaactt
atagtgtttattgcacacttttccttgcaagatgggtcttgtccttctccttttgcatct
ccaggaccttctagtcaggcatgtgataacttgagcttgagtgaccacttactaagagcc
acactaaatctcttgagaagggaagtttcagagcatggacatcatttacagcaatatttt
aatttgtttgtaatgtatgccaatttaggtgtggcagaaaaaacacagcttctgaaattg
aatgtacctgctacctttatgcttgtgtctttagacgaaggaccaggtcctccaatcaaa
tatcagtatgctgaattaggcaagttatattcagtagtgtctcagctgattcgttgttgc
aatgtgtcatcaacaatgcagtcttcaatcaatggtaatccccctctccccaatcctttc
ggtgaccttaatttatcacagcctataatgccaattcagcagaatgtgttagacatttta
tttgtgagaacaagttatgtgaagaaaattattgaagactgcagtaactcagaggatacc
atcaaattacttcgcttttgctcttgggagaatcctcagttctcatctactgtcctcagc
gaacttctctggcaggttgcatattcatatacctatgaacttcggccatatttagatcta
cttttccaaattttactgattgaggactcctggcagactcacagaattcataatgcactt
aaaggaattccagatgacagagatgggctgttcgatacaatacagcgctcgaagaatcac
tatcaaaaacgagcatatcagtgcataaaatgtatggtagctctatttagcagttgtcct
gttgcttaccagatcttacagggtaacggagatcttaaaagaaaatggacctgggcagtg
gaatggctaggagatgaacttgaaagaagaccatatactggcaatcctcagtatagttac
aacaattggtctcctccagtacaaagcaatgaaacagcaaatggttatttcttagaaaga
tcacatagtgctaggatgacacttgcaaaagcttgtgaactctgtccagaagaggagcca
gatgaccaggatgccccagatgagcatgagccctctccatcagaagatgccccattatat
cctcattcacctgcctctcagtatcaacagaataatcatgtacatggacagccatataca
ggaccagcagcacatcacttgaacaaccctcagaaaacaggccaacgaacacaagaaaat
tatgaaggcaatgaagaagtatcctcacctcagatgaaggatcagtga
DBGET
integrated database retrieval system
