KEGG   Homo sapiens (human): 8335
Entry
8335              CDS       T01001                                 
Symbol
H2AC4, H2A/m, H2AC8, H2AFM, HIST1H2AB
Name
(RefSeq) H2A clustered histone 4
  KO
K11251  histone H2A
Organism
hsa  Homo sapiens (human)
Pathway
hsa03082  ATP-dependent chromatin remodeling
hsa04217  Necroptosis
hsa04613  Neutrophil extracellular trap formation
hsa05034  Alcoholism
hsa05322  Systemic lupus erythematosus
Network
nt06523  Epigenetic regulation by Polycomb complexes
  Element
N01577  Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01586  Activation of PRC2.2 by ubiquitination of H2AK119
N01614  Activation of PRC2.2 by ubiquitination of H2AK119 in germline genes
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09126 Chromosome
   03082 ATP-dependent chromatin remodeling
    8335 (H2AC4)
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    8335 (H2AC4)
 09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    8335 (H2AC4)
 09160 Human Diseases
  09163 Immune disease
   05322 Systemic lupus erythematosus
    8335 (H2AC4)
  09165 Substance dependence
   05034 Alcoholism
    8335 (H2AC4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:hsa03036]
    8335 (H2AC4)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:hsa04147]
    8335 (H2AC4)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Nucleosome assembly factors
   Histones
    8335 (H2AC4)
Exosome [BR:hsa04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   8335 (H2AC4)
SSDB
Motif
Pfam: Histone_H2A_C Histone CBFD_NFYB_HMF
Other DBs
NCBI-GeneID: 8335
NCBI-ProteinID: NP_003504
OMIM: 602795
HGNC: 4734
Ensembl: ENSG00000278463
UniProt: P04908 Q08AJ9
Structure
LinkDB
Position
6:complement(26033092..26033618)
AA seq 130 aa
MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERVGAGAPVYLAAVLEYLT
AEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVTIAQGGVLPNIQAVLLPKK
TESHHKAKGK
NT seq 393 nt   +upstreamnt  +downstreamnt
atgtctggtcgcggcaaacaaggcggtaaagctcgcgccaaggctaagactcggtcttct
cgtgcaggtttgcagtttcctgtgggccgagtgcaccgcctgctccgcaaaggcaactac
tccgagcgcgtcggggctggcgcgccggtgtatctcgcggcggtgcttgagtacctgacc
gccgagatcctggagctggcgggcaatgcggcccgcgacaacaagaagacccgcatcatc
ccgcgccacctgcaattggccatccgcaatgacgaggagcttaataaactcttggggcgt
gtgaccatcgcgcagggtggcgttttgcctaatattcaggcggtgctgctgcctaagaaa
actgagagccatcataaggccaagggaaagtga

DBGET integrated database retrieval system