Homo sapiens (human): 84230
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Entry
84230 CDS
T01001
Symbol
LRRC8C, AD158, FAD158
Name
(RefSeq) leucine rich repeat containing 8 VRAC subunit C
KO
K22038
volume-regulated anion channel
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
hsa04040
]
84230 (LRRC8C)
Ion channels [BR:
hsa04040
]
Chloride channels
Chloride channel, volume-regulated (VRAC)
84230 (LRRC8C)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Pannexin_like
LRR_8
LRR_4
LRR_1
LRR_6
Motif
Other DBs
NCBI-GeneID:
84230
NCBI-ProteinID:
NP_115646
OMIM:
612889
HGNC:
25075
Ensembl:
ENSG00000171488
UniProt:
Q8TDW0
Structure
PDB
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All DBs
Position
1:89615824..89719533
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AA seq
803 aa
AA seq
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MIPVTEFRQFSEQQPAFRVLKPWWDVFTDYLSVAMLMIGVFGCTLQVMQDKIICLPKRVQ
PAQNHSSLSNVSQAVASTTPLPPPKPSPANPITVEMKGLKTDLDLQQYSFINQMCYERAL
HWYAKYFPYLVLIHTLVFMLCSNFWFKFPGSSSKIEHFISILGKCFDSPWTTRALSEVSG
EDSEEKDNRKNNMNRSNTIQSGPEDSLVNSQSLKSIPEKFVVDKSTAGALDKKEGEQAKA
LFEKVKKFRLHVEEGDILYAMYVRQTVLKVIKFLIIIAYNSALVSKVQFTVDCNVDIQDM
TGYKNFSCNHTMAHLFSKLSFCYLCFVSIYGLTCLYTLYWLFYRSLREYSFEYVRQETGI
DDIPDVKNDFAFMLHMIDQYDPLYSKRFAVFLSEVSENKLKQLNLNNEWTPDKLRQKLQT
NAHNRLELPLIMLSGLPDTVFEITELQSLKLEIIKNVMIPATIAQLDNLQELSLHQCSVK
IHSAALSFLKENLKVLSVKFDDMRELPPWMYGLRNLEELYLVGSLSHDISRNVTLESLRD
LKSLKILSIKSNVSKIPQAVVDVSSHLQKMCIHNDGTKLVMLNNLKKMTNLTELELVHCD
LERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHLRKLTVLKLWHNSITYIPEHIKKLT
SLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNKVES
LPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGDCRALKRA
GLVVEDALFETLPSDVREQMKTE
NT seq
2412 nt
NT seq
+upstream
nt +downstream
nt
atgattcccgtgacagaattccggcagttctctgagcagcagcctgccttccgagtgctg
aagccatggtgggatgtgtttaccgattacctctcagtagccatgctcatgatcggcgtg
tttggatgtactttacaggtcatgcaagacaagataatctgccttccgaaaagagtgcag
cctgctcagaaccactcttccctttcgaatgtctctcaagcagttgccagtaccactcca
ctgcctccacctaaaccatctcctgctaaccccatcactgtggaaatgaaaggcctgaag
acagatttggaccttcagcagtacagctttataaatcagatgtgttatgagcgagccctc
cactggtatgccaagtatttcccttaccttgtcctcatccataccctggtctttatgctc
tgcagtaacttttggttcaaattccctggttccagctccaaaatagaacatttcatctcc
attctggggaagtgttttgactctccttggaccacacgggctttatctgaagtgtctggg
gaggactcagaagaaaaggacaacaggaagaacaacatgaacaggtccaacaccatccaa
tctggtccagaagacagcctggtcaactctcagtctttaaagtccattcctgagaagttt
gtagttgataaatccactgcaggggctctggataaaaaggaaggtgagcaggctaaggcc
ttatttgagaaggtgaagaagttcaggctgcatgtggaagaaggtgatattctatatgcc
atgtatgttcgccagactgtacttaaagttatcaaattcctaatcatcattgcatataat
agtgctctggtttccaaggtccagtttacagtggactgtaatgtggacattcaggacatg
actggatataaaaacttttcttgcaatcataccatggcacacttgttctcaaaactgtcc
ttttgctatctgtgctttgttagtatctatggattgacgtgcctttataccttatactgg
ctgttctaccgttctctacgggaatattcctttgagtatgtccgtcaggagactggaatt
gatgatattccagatgtgaaaaatgactttgcttttatgcttcatatgatagatcagtat
gaccctctctattccaagagatttgcagtgttcctgtctgaagtcagtgaaaacaaatta
aagcagctgaacttaaataacgaatggactcctgataaactgaggcagaagctacagaca
aatgcccataatcgactggaattgcctcttatcatgctctctggccttccagacactgtt
tttgaaatcacagagttgcaatctctaaaacttgaaatcattaagaacgtaatgatacca
gccaccattgcacagctagacaatcttcaagagctctctctgcaccagtgttctgtcaaa
atccacagtgcggcgctctctttcctgaaggaaaacctcaaggtcttgagcgtcaagttt
gatgacatgagggaactccccccctggatgtatgggctccgaaatctggaagagctgtac
ctagttggctctctaagtcatgatatttccagaaatgtcacccttgagtctctgcgggat
ctcaaaagccttaaaattctctctatcaaaagcaacgtttccaaaatccctcaggcagtg
gttgatgtttccagccatctccagaagatgtgcatacataatgatggcaccaagctggtg
atgctcaacaacttaaagaagatgaccaatctgacagagctggagctggtccactgtgac
ctggagcgtattcctcatgctgtgttcagcctactcagcctccaggaattggacctgaag
gaaaacaatctgaaatctatagaagaaatcgttagctttcagcacttaagaaagttgaca
gtgctaaaactgtggcataacagcatcacctacatcccagagcatataaagaaactcacc
agcctggaacgcctgtcctttagtcacaataaaatagaggtgctgccttcccacctcttc
ctatgcaacaagatccgatacttggacttatcgtacaatgacattcgatttatcccccct
gaaattggagttctacaaagtttacagtatttttccatcacatgtaacaaagtggaaagc
cttccagatgaactctacttctgcaagaaacttaaaactctgaagattggaaaaaacagc
ctatctgtactttcaccgaaaattggaaatttgctatttctttcctacttagatgtaaaa
ggtaatcactttgaaatcctccctcctgaactgggtgactgtcgggctctgaagcgagct
ggtttagttgtagaagatgctctgtttgaaactctgccttctgacgtccgggagcaaatg
aaaacagaataa
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