Homo sapiens (human): 8425
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Entry
8425 CDS
T01001
Symbol
LTBP4, ARCL1C, LTBP-4, LTBP4L, LTBP4S
Name
(RefSeq) latent transforming growth factor beta binding protein 4
KO
K08023
latent transforming growth factor beta binding protein 2/3/4
Organism
hsa
Homo sapiens (human)
Network
nt06507
TGFB signaling
Element
N01460
Plasmin mediated activation of latent TGF-beta
Disease
H00557
Cutis laxa
H00904
Cutis laxa with severe pulmonary, gastrointestinal, and urinary abnormalities
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
8425 (LTBP4)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
EGF-like domain-containing proteins
hEGF / cEGF domain-containing proteins
8425 (LTBP4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
EGF_CA
cEGF
TB
EGF_3
EGF
hEGF
FXa_inhibition
Plasmod_Pvs28
EGF_2
EGF_C8A_B_C6
Motif
Other DBs
NCBI-GeneID:
8425
NCBI-ProteinID:
NP_001036009
OMIM:
604710
HGNC:
6717
Ensembl:
ENSG00000090006
UniProt:
Q8N2S1
B3KXY6
LinkDB
All DBs
Position
19:40593166..40629820
Genome browser
AA seq
1624 aa
AA seq
DB search
MPRPGTSGRRPLLLVLLLPLFAAATSAASPSPSPSQVVEVPGVPSRPASVAVCRCCPGQT
SRRSRCIRAFCRVRSCQPKKCAGPQRCLNPVPAVPSPSPSVRKRQVSLNWQPLTLQEARA
LLKRRRPRGPGGRGLLRRRPPQRAPAGKAPVLCPLICHNGGVCVKPDRCLCPPDFAGKFC
QLHSSGARPPAPAVPGLTRSVYTMPLANHRDDEHGVASMVSVHVEHPQEASVVVHQVERV
SGPWEEADAEAVARAEAAARAEAAAPYTVLAQSAPREDGYSDASGFGYCFRELRGGECAS
PLPGLRTQEVCCRGAGLAWGVHDCQLCSERLGNSERVSAPDGPCPTGFERVNGSCEDVDE
CATGGRCQHGECANTRGGYTCVCPDGFLLDSSRSSCISQHVISEAKGPCFRVLRDGGCSL
PILRNITKQICCCSRVGKAWGRGCQLCPPFGSEGFREICPAGPGYHYSASDLRYNTRPLG
QEPPRVSLSQPRTLPATSRPSAGFLPTHRLEPRPEPRPDPRPGPELPLPSIPAWTGPEIP
ESGPSSGMCQRNPQVCGPGRCISRPSGYTCACDSGFRLSPQGTRCIDVDECRRVPPPCAP
GRCENSPGSFRCVCGPGFRAGPRAAECLDVDECHRVPPPCDLGRCENTPGSFLCVCPAGY
QAAPHGASCQDVDECTQSPGLCGRGACKNLPGSFRCVCPAGFRGSACEEDVDECAQEPPP
CGPGRCDNTAGSFHCACPAGFRSRGPGAPCQDVDECARSPPPCTYGRCENTEGSFQCVCP
MGFQPNTAGSECEDVDECENHLACPGQECVNSPGSFQCRTCPSGHHLHRGRCTDVDECSS
GAPPCGPHGHCTNTEGSFRCSCAPGYRAPSGRPGPCADVNECLEGDFCFPHGECLNTDGS
FACTCAPGYRPGPRGASCLDVDECSEEDLCQSGICTNTDGSFECICPPGHRAGPDLASCL
DVDECRERGPALCGSQRCENSPGSYRCVRDCDPGYHAGPEGTCDDVDECQEYGPEICGAQ
RCENTPGSYRCTPACDPGYQPTPGGGCQDVDECRNRSFCGAHAVCQNLPGSFQCLCDQGY
EGARDGRHCVDVNECETLQGVCGAALCENVEGSFLCVCPNSPEEFDPMTGRCVPPRTSAG
TFPGSQPQAPASPVLPARPPPPPLPRRPSTPRQGPVGSGRRECYFDTAAPDACDNILARN
VTWQECCCTVGEGWGSGCRIQQCPGTETAEYQSLCPHGRGYLAPSGDLSLRRDVDECQLF
RDQVCKSGVCVNTAPGYSCYCSNGYYYHTQRLECIDNDECADEEPACEGGRCVNTVGSYH
CTCEPPLVLDGSQRRCVSNESQSLDDNLGVCWQEVGADLVCSHPRLDRQATYTECCCLYG
EAWGMDCALCPAQDSDDFEALCNVLRPPAYSPPRPGGFGLPYEYGPDLGPPYQGLPYGPE
LYPPPALPYDPYPPPPGPFARREAPYGAPRFDMPDFEDDGGPYGESEAPAPPGPGTRWPY
RSRDTRRSFPEPEEPPEGGSYAGSLAEPYEELEAEECGILDGCTNGRCVRVPEGFTCRCF
DGYRLDMTRMACVDINECDEAEAASPLCVNARCLNTDGSFRCICRPGFAPTHQPHHCAPA
RPRA
NT seq
4875 nt
NT seq
+upstream
nt +downstream
nt
atgccgaggcctggcaccagcggccgccgccccctcctgctggtgctgttgctgccgctc
ttcgcagccgccacctccgccgccagccccagccccagccccagccaggtcgtcgaggtc
ccgggggtccccagccgcccggccagcgttgctgtttgtcgctgctgcccgggccagacg
tctaggaggagccgctgcatccgagccttctgcagggtccgaagctgccagcccaaaaag
tgtgcaggcccccagcggtgcctgaacccagtgcctgcagtgcccagtcccagccccagc
gtgaggaagagacaggtgtccctcaactggcagccactgacgctccaggaggccagagct
ctactgaagcggcggcggccccgggggccagggggccggggactactgagaaggaggccc
ccacagcgtgcccccgctggcaaggccccggtcctgtgtcccttgatctgtcacaatggc
ggtgtgtgcgtgaagcctgaccgctgcctctgtcccccggacttcgctggcaagttctgc
cagttgcactcctcgggcgcccggcccccggccccggctgtaccaggcctcacccgctcc
gtgtacactatgccactggccaaccaccgcgacgacgagcacggcgtggcatctatggtg
agcgtccacgtggagcacccgcaggaggcgtcggtggtggtgcaccaggtggagcgtgtg
tctggcccttgggaggaggcggacgctgaggcggtggcgcgggcggaagcggcggcgcgg
gcggaggcggcagcgccctacacggtgttggcacagagcgcgccgcgggaggacggctac
tcagatgcctcgggcttcggttactgctttcgggagctgcgcggaggcgaatgcgcgtcc
ccgctgcccgggctccggacgcaggaggtctgctgccgaggggccggcttggcctggggc
gttcacgactgtcagctgtgctccgagcgcctggggaactccgaaagagtgagcgcccca
gatggaccttgtccaaccggctttgaaagagttaatgggtcctgcgaagatgtggatgag
tgcgcgactggcgggcgctgccagcacggcgagtgtgcaaacacgcgcggcgggtacacg
tgtgtgtgccccgacggctttctgctcgactcgtcccgcagcagctgcatctcccaacac
gtgatctcagaggccaaagggccctgcttccgcgtgctccgcgacggcggctgttcgctg
cccattctgcggaacatcactaaacagatctgctgctgcagccgcgtaggcaaggcctgg
ggccggggctgccagctctgcccacccttcggctcagagggtttccgggagatctgcccg
gctggtcctggttaccactactcggcctccgacctccgctacaacaccagacccctgggc
caggagccaccccgagtgtcactcagccagcctcgtaccctgccagccacctctcggcca
tctgcaggctttctgcccacccatcgcctggagccccggcctgaaccccggcccgatccc
cggcccggccctgagcttcccttgcccagcatccctgcctggactggtcctgagattcct
gaatcaggtccctcctccggcatgtgtcagcgcaacccccaggtctgcggcccaggacgc
tgcatttcccggcccagcggctacacctgcgcttgcgactctggcttccggctcagcccc
cagggcacccgatgcattgatgtggacgaatgtcgccgcgtgcccccgccctgtgctccc
gggcgctgcgagaactcaccaggcagcttccgctgcgtgtgcggcccgggcttccgagcc
ggcccacgggctgcggaatgcctggatgtggacgagtgccaccgcgtgccgccgccgtgt
gacctcgggcgctgcgagaacacgccaggcagcttcctgtgcgtgtgccccgccgggtac
caggctgcaccgcacggagccagctgccaggatgtggatgaatgcacccagagcccaggc
ctgtgtggccgaggggcctgcaagaacctgcctggctctttccgctgtgtttgcccggct
ggcttccggggctcggcgtgtgaagaggatgtggatgagtgtgcccaggagccgccgccc
tgtgggcccggccgctgtgacaacacggcaggctcctttcactgtgcctgccctgctggc
ttccgctcccgagggcccggggccccctgccaagatgtggatgagtgtgcccgaagcccc
ccaccctgcacctacggccggtgtgagaacacagaaggcagcttccagtgtgtctgcccc
atgggcttccaacccaacactgctggctccgagtgcgaggatgtggatgagtgtgagaac
cacctcgcatgccctgggcaggagtgtgtgaactcgcccggctccttccagtgcaggacc
tgtccttctggccaccacctgcaccgtggcagatgcactgatgtggacgaatgcagttcg
ggtgcccctccctgtggtccccacggccactgcactaacaccgaaggctccttccgctgc
agctgcgcgccaggctaccgggcgccgtcgggtcggcccgggccctgcgcagacgtgaac
gagtgcctggagggcgatttctgcttccctcacggcgagtgcctcaacactgacggctcc
tttgcctgtacttgtgcccctggctaccgacccggaccccgcggagcctcttgcctcgac
gttgacgagtgcagcgaggaggacctttgccagagcggcatctgtaccaacaccgacggc
tccttcgagtgcatctgtcctccgggacaccgcgctggcccggacctcgcctcctgcctc
gacgtggacgaatgtcgcgagcgaggcccagccctgtgcgggtcgcagcgctgtgagaac
tctcccggctcctaccgctgtgtccgggactgcgatcctgggtaccacgcgggccccgag
ggcacctgtgacgatgtggatgagtgccaagaatatggtcccgagatttgtggagcccag
cgttgtgagaacacccctggctcctaccgctgcacaccagcctgtgaccctggctatcag
cccacgccagggggcggatgccaggatgtggacgaatgccggaaccggtccttctgcggt
gcccacgccgtgtgccagaacctgcccggctccttccagtgcctctgtgaccagggttac
gagggggcacgggatgggcgtcactgcgtggatgtgaacgagtgtgaaacactacagggt
gtatgtggagctgccctgtgtgaaaatgtcgaaggctccttcctctgtgtctgccccaac
agcccggaagagtttgaccccatgactggacgctgtgttcccccacgaacttctgctggc
acgttcccaggctcgcagccccaggcacctgctagccccgttctgcccgccaggccacct
ccgccacccctgccccgccgacccagcacacctaggcagggccctgtggggagtgggcgc
cgggagtgctactttgacacagcggccccggatgcatgtgacaacatcctggctcggaat
gtgacatggcaggagtgctgctgtactgtgggtgagggctggggcagcggctgccgcatc
cagcagtgcccgggcaccgagacagctgagtaccagtcattgtgccctcacggccggggc
tacctggcgcccagtggagacctgagcctccggagagacgtggacgaatgtcagctcttc
cgagaccaggtgtgcaagagtggcgtgtgtgtgaacacggccccgggctactcatgctat
tgcagcaacggctactactaccacacacagcggctggagtgcatcgacaatgacgagtgc
gccgatgaggaaccggcctgtgagggcggccgctgtgtcaacactgtgggctcttatcac
tgtacctgcgagcccccactggtgctggatggctcgcagcgccgctgcgtctccaacgag
agccagagcctcgatgacaatctgggagtgtgctggcaggaagtgggggctgacctcgtg
tgcagccaccctcggctggaccgtcaggccacctacacagagtgctgctgcctgtatgga
gaggcctggggcatggactgcgccctctgccctgcgcaggactcagatgacttcgaggcc
ctgtgcaatgtgctacgcccccccgcatatagccccccgcgaccaggtggctttggactc
ccctacgagtacggcccagacttaggtccaccttaccagggcctcccatatgggcctgag
ttgtacccaccacctgcgctaccctacgacccctacccaccgccacctgggcccttcgcc
cgccgggaggctccttatggggcaccccgcttcgacatgccagactttgaggacgatggt
ggcccctatggcgaatctgaggctcctgcgccacctggcccgggcacccgctggccctat
cggtcccgggacacccgccgctccttcccagagcccgaggagcctcctgaaggtggaagc
tatgctggttccctggctgagccctacgaggagctggaggcggaggagtgcgggatcctg
gacggctgcaccaacggccgctgcgtgcgcgtccccgaaggcttcacctgccgttgcttc
gacggctaccgcctggacatgacccgcatggcctgcgttgacatcaacgagtgtgatgag
gccgaggctgcctccccgctgtgcgtcaacgcgcgttgcctcaacacggatggctccttc
cgctgcatctgccgcccgggattcgcacccacgcaccagccgcaccactgtgcgcccgca
cggccccgggcctga
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