Homo sapiens (human): 84515
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Entry
84515 CDS
T01001
Symbol
MCM8, C20orf154, POF10, dJ967N21.5
Name
(RefSeq) minichromosome maintenance 8 homologous recombination repair factor
KO
K10737
DNA helicase MCM8 [EC:
5.6.2.4
]
Organism
hsa
Homo sapiens (human)
Network
nt06508
Interstrand crosslink repair
Element
N01466
Homologous recombination in ICLR
Disease
H00627
Premature ovarian failure
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
hsa03032
]
84515 (MCM8)
03400 DNA repair and recombination proteins [BR:
hsa03400
]
84515 (MCM8)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.4 DNA 3'-5' helicase
84515 (MCM8)
DNA replication proteins [BR:
hsa03032
]
Eukaryotic type
DNA Replication Initiation Factors
Other initiation factors
84515 (MCM8)
DNA repair and recombination proteins [BR:
hsa03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Other HR factors
84515 (MCM8)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MCM
WHD_MCM8
MCM_lid
MCM_OB
Mg_chelatase
AAA_5
AAA_3
AAA_22
AAA
AAA_16
FtsK_SpoIIIE
Motif
Other DBs
NCBI-GeneID:
84515
NCBI-ProteinID:
NP_001268449
OMIM:
608187
HGNC:
16147
Ensembl:
ENSG00000125885
UniProt:
Q9UJA3
Structure
PDB
PDBj
LinkDB
All DBs
Position
20:5950652..5998977
Genome browser
AA seq
840 aa
AA seq
DB search
MNGEYRGRGFGRGRFQSWKRGRGGGNFSGKWREREHRPDLSKTTGKRTSEQTPQFLLSTK
TPQSMQSTLDRFIPYKGWKLYFSEVYSDSSPLIEKIQAFEKFFTRHIDLYDKDEIERKGS
ILVDFKELTEGGEVTNLIPDIATELRDAPEKTLACMGLAIHQVLTKDLERHAAELQAQEG
LSNDGETMVNVPHIHARVYNYEPLTQLKNVRANYYGKYIALRGTVVRVSNIKPLCTKMAF
LCAACGEIQSFPLPDGKYSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDD
QREAGRIPRTIECELVHDLVDSCVPGDTVTITGIVKVSNAEEGSRNKNDKCMFLLYIEAN
SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV
KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN
TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQALLEAMEQQSIS
LAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNEH
HDHLLSEHVIAIRAGKQRTISSATVARMNSQDSNTSVLEVVSEKPLSERLKVVPGETIDP
IPHQLLRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSPITTRQLESLIRLT
EARARLELREEATKEDAEDIVEIMKYSMLGTYSDEFGNLDFERSQHGSGMSNRSTAKRFI
SALNNVAERTYNNIFQFHQLRQIAKELNIQVADFENFIGSLNDQGYLLKKGPKVYQLQTM
NT seq
2523 nt
NT seq
+upstream
nt +downstream
nt
atgaatggagagtatagaggcagaggatttggacgaggaagatttcaaagctggaaaagg
ggaagaggtggtgggaacttctcaggaaaatggagagaaagagaacacagacctgatctg
agtaaaaccacaggaaaacgtacttctgaacaaaccccacagtttttgctttcaacaaag
accccacagtcaatgcagtcaacattggatcgattcataccatataaaggctggaagctt
tatttctctgaagtttacagcgatagctctcctttgattgagaagattcaagcatttgaa
aaatttttcacaaggcatattgatttgtatgacaaggatgaaatagaaagaaagggaagt
attttggtagattttaaagaactgacagaaggtggtgaagtaactaacttgataccagat
atagcaactgaactaagagatgcacctgagaaaaccttggcttgcatgggtttggcaata
catcaggtgttaactaaggaccttgaaaggcatgcagctgagttacaagcccaggaagga
ttgtctaatgatggagaaacaatggtaaatgtgccacatattcatgcaagggtgtacaac
tatgagcctttgacacagctcaagaatgtcagagcaaattactatggaaaatacattgct
ctaagagggacagtggttcgtgtcagtaatataaagcctctttgcaccaagatggctttt
ctttgtgctgcatgtggagaaattcagagctttcctcttccagatggaaaatacagtctt
cccacaaagtgtcctgtgcctgtgtgtcgaggcaggtcatttactgctctccgcagctct
cctctcacagttacgatggactggcagtcaatcaaaatccaggaattgatgtctgatgat
cagagagaagcaggtcggattccacgaacaatagaatgtgagcttgttcatgatcttgtg
gatagctgtgtcccgggagacacagtgactattactggaattgtcaaagtctcaaatgcg
gaagaaggttctcgaaataagaatgacaagtgtatgttccttttgtatattgaagcaaat
tctattagtaatagcaaaggacagaaaacaaagagttctgaggatgggtgtaagcatgga
atgttgatggagttctcacttaaagacctttatgccatccaagagattcaagctgaagaa
aacctgtttaaactcattgtcaactcgctttgccctgtcatttttggtcatgaacttgtt
aaagcaggtttggcattagcactctttggaggaagccagaaatacgcagatgacaaaaac
agaattccaattcggggagacccccacatccttgttgttggagatccaggcctaggaaaa
agtcaaatgctacaggcagcgtgcaatgttgccccacgtggcgtgtatgtttgtggtaac
accacgaccacctctggtctgacggtaactctttcaaaagatagttcctctggagatttt
gctttggaagctggtgccctggtacttggtgatcaaggtatttgtggaatcgatgaattt
gataagatggggaatcaacatcaagccttgttggaagccatggagcagcaaagtattagt
cttgctaaggctggtgtggtttgtagccttcctgcaagaacttccattattgctgctgca
aatccagttggaggacattacaataaagccaaaacagtttctgagaatttaaaaatgggg
agtgcactactatccagatttgatttggtctttatcctgttagatactccaaatgagcat
catgatcacttactctctgaacatgtgattgcaataagagctggaaagcagagaaccatt
agcagtgccacagtagctcgtatgaatagtcaagattcaaatacttccgtacttgaagta
gtttctgagaagccattatcagaaagactaaaggtggttcctggagaaacaatagatccc
attccccaccagctattgagaaagtacattggctatgctcggcagtatgtgtacccaagg
ctatccacagaagctgctcgagttcttcaagatttttaccttgagctccggaaacagagc
cagaggttaaatagctcaccaatcactaccaggcagctggaatctttgattcgtctgaca
gaggcacgagcaaggttggaattgagagaggaagcaaccaaagaagacgctgaggatata
gtggaaattatgaaatatagcatgctaggaacttactctgatgaatttgggaacctagat
tttgagcgatcccagcatggttctggaatgagcaacaggtcaacagcgaaaagatttatt
tctgctctcaacaacgttgctgaaagaacttataataatatatttcaatttcatcaactt
cggcagattgccaaagaactaaacattcaggttgctgattttgaaaattttattggatca
ctaaatgaccagggttacctcttgaaaaaaggcccaaaagtttaccagcttcaaactatg
taa
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