KEGG   Homo sapiens (human): 8464
Entry
8464              CDS       T01001                                 
Symbol
SUPT3H, SPT3, SPT3L
Name
(RefSeq) SPT3 homolog, SAGA and STAGA complex component
  KO
K11313  transcription initiation protein SPT3
Organism
hsa  Homo sapiens (human)
Pathway
hsa05202  Transcriptional misregulation in cancer
Network
nt06240  Transcription (cancer)
  Element
N00119  MLL-AF4 fusion to transcriptional activation
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    8464 (SUPT3H)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:hsa03021]
    8464 (SUPT3H)
   03036 Chromosome and associated proteins [BR:hsa03036]
    8464 (SUPT3H)
Transcription machinery [BR:hsa03021]
 Eukaryotic type
  RNA polymerase II system
   Coactivators
    SAGA/TFTC/STAGA complex
     8464 (SUPT3H)
Chromosome and associated proteins [BR:hsa03036]
 Eukaryotic type
  Histone modification proteins
   HAT complexes
    PCAF complex
     8464 (SUPT3H)
    STAGA complex
     8464 (SUPT3H)
    TFTC complex
     8464 (SUPT3H)
    SAGA complex
     8464 (SUPT3H)
    SLIK complex
     8464 (SUPT3H)
SSDB
Motif
Pfam: TFIID-18kDa DUF4093 CBFD_NFYB_HMF Hit1_C
Other DBs
NCBI-GeneID: 8464
NCBI-ProteinID: NP_003590
OMIM: 602947
HGNC: 11466
Ensembl: ENSG00000196284
UniProt: O75486
Structure
LinkDB
Position
6:complement(44809057..45377934)
AA seq 317 aa
MNNTAASPMSTATSSSGRSTGKSISFATELQSMMYSLGDARRPLHETAVLVEDVVHTQLI
NLLQQAAEVSQLRGARVITPEDLLFLMRKDKKKLRRLLKYMFIRDYKSKIVKGIDEDDLL
EDKLSGSNNANKRQKIAQDFLNSIDQTGELLAMFEDDEIDEVKQERMERAERQTRIMDSA
QYAEFCESRQLSFSKKASKFRDWLDCSSMEIKPNVVAMEILAYLAYETVAQLVDLALLVR
QDMVTKAGDPFSHAISATFIQYHNSAESTAACGVEAHSDAIQPCHIREAIRRYSHRIGPL
SPFTNAYRRNGMAFLAC
NT seq 954 nt   +upstreamnt  +downstreamnt
atgaataatacggcagctagtccaatgtctactgcaacttcaagtagtggaaggagtaca
gggaagtctataagctttgcaacagaattacagagtatgatgtattctttaggtgatgct
agaaggcctcttcatgaaacagcagttttggtagaagatgtggtacacactcagttaatt
aatctgttacagcaagctgctgaagtttctcagctgcggggagcaagggtaatcactcct
gaagatcttctgtttttgatgcgcaaagataagaaaaaacttagaagactgctaaaatac
atgtttatccgagactacaaatcaaagattgtcaaaggcatcgatgaggatgatcttctc
gaagacaaattgagtggcagcaataatgcgaacaaaagacaaaagattgctcaggacttc
ctcaactctattgaccagacaggagaacttttagcaatgtttgaagatgacgaaattgat
gaagttaaacaagaaagaatggagagagcagaaagacaaactcgaattatggattcagct
caatatgcagaattctgtgaaagtcgacaattaagtttctccaaaaaagcttccaaattt
cgagactggttggactgcagcagtatggagataaaacccaatgttgtcgcaatggaaatc
ttagcatatttagcgtatgaaactgtggcacagttagtggatctggctcttcttgtgagg
caagacatggtaaccaaggcaggggaccccttcagccatgccatttctgcaaccttcatt
cagtatcacaactctgctgagagcactgcagcctgtggtgttgaggctcacagcgatgcc
atccagccctgccacatcagagaggccattcgacgctacagccacaggattggcccactt
tccccattcacaaatgcctaccgcaggaatgggatggcttttctagcctgctga

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