KEGG   Homo sapiens (human): 847
Entry
847               CDS       T01001                                 
Symbol
CAT
Name
(RefSeq) catalase
  KO
K03781  catalase [EC:1.11.1.6]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00380  Tryptophan metabolism
hsa00630  Glyoxylate and dicarboxylate metabolism
hsa01100  Metabolic pathways
hsa01200  Carbon metabolism
hsa04068  FoxO signaling pathway
hsa04146  Peroxisome
hsa04211  Longevity regulating pathway
hsa04213  Longevity regulating pathway - multiple species
hsa05014  Amyotrophic lateral sclerosis
hsa05022  Pathways of neurodegeneration - multiple diseases
hsa05208  Chemical carcinogenesis - reactive oxygen species
Network
nt06253  Antioxidant system (cancer)
  Element
N01388  SOD/Cat-mediated ROS neutralization
N01391  Lead to SOD/Cat-mediated ROS neutralization
Disease
H00203  Acatalasemia
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00630 Glyoxylate and dicarboxylate metabolism
    847 (CAT)
  09105 Amino acid metabolism
   00380 Tryptophan metabolism
    847 (CAT)
 09130 Environmental Information Processing
  09132 Signal transduction
   04068 FoxO signaling pathway
    847 (CAT)
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    847 (CAT)
 09150 Organismal Systems
  09149 Aging
   04211 Longevity regulating pathway
    847 (CAT)
   04213 Longevity regulating pathway - multiple species
    847 (CAT)
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    847 (CAT)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    847 (CAT)
   05022 Pathways of neurodegeneration - multiple diseases
    847 (CAT)
Enzymes [BR:hsa01000]
 1. Oxidoreductases
  1.11  Acting on a peroxide as acceptor
   1.11.1  Peroxidases
    1.11.1.6  catalase
     847 (CAT)
SSDB
Motif
Pfam: Catalase Catalase-rel
Other DBs
NCBI-GeneID: 847
NCBI-ProteinID: NP_001743
OMIM: 115500
HGNC: 1516
Ensembl: ENSG00000121691
UniProt: P04040 A0A384P5Q0
Structure
LinkDB
Position
11:34438934..34472060
AA seq 527 aa
MADSRDPASDQMQHWKEQRAAQKADVLTTGAGNPVGDKLNVITVGPRGPLLVQDVVFTDE
MAHFDRERIPERVVHAKGAGAFGYFEVTHDITKYSKAKVFEHIGKKTPIAVRFSTVAGES
GSADTVRDPRGFAVKFYTEDGNWDLVGNNTPIFFIRDPILFPSFIHSQKRNPQTHLKDPD
MVWDFWSLRPESLHQVSFLFSDRGIPDGHRHMNGYGSHTFKLVNANGEAVYCKFHYKTDQ
GIKNLSVEDAARLSQEDPDYGIRDLFNAIATGKYPSWTFYIQVMTFNQAETFPFNPFDLT
KVWPHKDYPLIPVGKLVLNRNPVNYFAEVEQIAFDPSNMPPGIEASPDKMLQGRLFAYPD
THRHRLGPNYLHIPVNCPYRARVANYQRDGPMCMQDNQGGAPNYYPNSFGAPEQQPSALE
HSIQYSGEVRRFNTANDDNVTQVRAFYVNVLNEEQRKRLCENIAGHLKDAQIFIQKKAVK
NFTEVHPDYGSHIQALLDKYNAEKPKNAIHTFVQSGSHLAAREKANL
NT seq 1584 nt   +upstreamnt  +downstreamnt
atggctgacagccgggatcccgccagcgaccagatgcagcactggaaggagcagcgggcc
gcgcagaaagctgatgtcctgaccactggagctggtaacccagtaggagacaaacttaat
gttattacagtagggccccgtgggccccttcttgttcaggatgtggttttcactgatgaa
atggctcattttgaccgagagagaattcctgagagagttgtgcatgctaaaggagcaggg
gcctttggctactttgaggtcacacatgacattaccaaatactccaaggcaaaggtattt
gagcatattggaaagaagactcccatcgcagttcggttctccactgttgctggagaatcg
ggttcagctgacacagttcgggaccctcgtgggtttgcagtgaaattttacacagaagat
ggtaactgggatctcgttggaaataacacccccattttcttcatcagggatcccatattg
tttccatcttttatccacagccaaaagagaaatcctcagacacatctgaaggatccggac
atggtctgggacttctggagcctacgtcctgagtctctgcatcaggtttctttcttgttc
agtgatcgggggattccagatggacatcgccacatgaatggatatggatcacatactttc
aagctggttaatgcaaatggggaggcagtttattgcaaattccattataagactgaccag
ggcatcaaaaacctttctgttgaagatgcggcgagactttcccaggaagatcctgactat
ggcatccgggatctttttaacgccattgccacaggaaagtacccctcctggactttttac
atccaggtcatgacatttaatcaggcagaaacttttccatttaatccattcgatctcacc
aaggtttggcctcacaaggactaccctctcatcccagttggtaaactggtcttaaaccgg
aatccagttaattactttgctgaggttgaacagatagccttcgacccaagcaacatgcca
cctggcattgaggccagtcctgacaaaatgcttcagggccgcctttttgcctatcctgac
actcaccgccatcgcctgggacccaattatcttcatatacctgtgaactgtccctaccgt
gctcgagtggccaactaccagcgtgacggcccgatgtgcatgcaggacaatcagggtggt
gctccaaattactaccccaacagctttggtgctccggaacaacagccttctgccctggag
cacagcatccaatattctggagaagtgcggagattcaacactgccaatgatgataacgtt
actcaggtgcgggcattctatgtgaacgtgctgaatgaggaacagaggaaacgtctgtgt
gagaacattgccggccacctgaaggatgcacaaattttcatccagaagaaagcggtcaag
aacttcactgaggtccaccctgactacgggagccacatccaggctcttctggacaagtac
aatgctgagaagcctaagaatgcgattcacacctttgtgcagtccggatctcacttggcg
gcaagggagaaggcaaatctgtga

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