Homo sapiens (human): 8509
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Entry
8509 CDS
T01001
Symbol
NDST2, HSST2, N-HSST_2, NST2
Name
(RefSeq) N-deacetylase and N-sulfotransferase 2
KO
K02577
heparan sulfate N-deacetylase/N-sulfotransferase NDST2 [EC:3.5.1.-
2.8.2.8
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00534
Glycosaminoglycan biosynthesis - heparan sulfate / heparin
hsa01100
Metabolic pathways
Module
hsa_M00059
Glycosaminoglycan biosynthesis, heparan sulfate backbone
Network
nt06029
Glycosaminoglycan biosynthesis
Element
N01582
Heparan sulfate biosynthesis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00534 Glycosaminoglycan biosynthesis - heparan sulfate / heparin
8509 (NDST2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
hsa01003
]
8509 (NDST2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.8 Transferring sulfur-containing groups
2.8.2 Sulfotransferases
2.8.2.8 [heparan sulfate]-glucosamine N-sulfotransferase
8509 (NDST2)
Glycosyltransferases [BR:
hsa01003
]
Unclassified
Sulfotransferases
8509 (NDST2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HSNSD-CE
HSNSD_N
Sulfotransfer_1
Sulfotransfer_3
Motif
Other DBs
NCBI-GeneID:
8509
NCBI-ProteinID:
NP_003626
OMIM:
603268
HGNC:
7681
Ensembl:
ENSG00000166507
UniProt:
P52849
B4E139
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All DBs
Position
10:complement(73801916..73811820)
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AA seq
883 aa
AA seq
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MLQLWKVVRPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGA
AGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPG
RGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLL
SAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPV
LLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYL
TGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGK
FYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGI
PTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVL
PRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLY
TFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTC
DRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDF
FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG
DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL
RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD
TESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHSSLG
NT seq
2652 nt
NT seq
+upstream
nt +downstream
nt
atgctccagttgtggaaggtggtacgcccagctcggcagctggaactgcaccgcctcata
ctgctgctgatcgctttcagcctgggctccatgggcttcctggcttattatgtgtccacc
agccctaaggccaaggaacccttgcccctgcccttgggagactgcagcagcggtggggca
gctggtcctggccctgcacggcctccagttccacctcggccccccaggcctccagagaca
gctcgaactgaacccgtggtccttgtgtttgtggagagtgcatactcacagctggggcag
gaaattgtggccatcctggagtctagtcgttttcgttatagcactgagttggcacctggc
cgaggggacatgcccacattgactgataatacccatggccgctatgtcttggtcatttat
gagaacctgctcaagtatgtcaacctggatgcctggagtcgggaactgctagaccggtac
tgcgtggagtatggtgtgggcatcattggctttttccgagcccacgagcacagcctactg
agcgcccagctcaagggctttcccctttttttacactcaaacttggggctccgggactac
caagtgaatccttctgccccgctactgcatctcacacgccccagccgcctagaaccaggg
ccactgcctggtgatgactggaccatcttccaatccaatcatagtacatatgaaccagtg
cttcttgccagccttcggccagctgagcccgcagtgccaggaccagttcttcgtcgggcc
cggcttcccactgtggtacaggacctggggcttcatgatggcatccagcgggtgctcttt
ggacatggcctttccttctggctccacaaacttatcttcgttgatgctgttgcatacctc
actggcaagcgcctctgcctggaccttgaccgctacatcttggtagacatcgatgacatc
tttgtgggcaaggaagggacccgcatgaaggtggctgatgttgaggctctgttgaccacc
cagaacaaactcaggaccttagttcccaacttcaccttcaacttgggcttctcgggcaag
ttctatcatactgggacagaggaggaggatgcaggggacgacatgctgctgaagcaccgc
aaagagttctggtggttcccccacatgtggagccacatgcagccacacctgttccacaat
cgctccgtgctggctgaccagatgaggctcaacaaacagtttgctctggagcatgggatt
cccacggacctggggtatgctgtggccccccaccactcgggtgtgtaccccatccacacg
cagctctatgaggcctggaaatccgtgtggggcatccaggtgaccagcactgaggagtat
ccccatctccgccctgcccgctaccgccgtggcttcattcacaatggcattatggtgctg
ccccggcagacatgtggcctcttcactcacacaatcttctataatgagtatcctggaggc
tctcgtgaactagaccggagcatccgaggtggagagctctttctgacagtgctgcttaat
ccgatcagcatctttatgacccatctgtccaattatggaaatgaccggctgggcctatac
acctttgagagcttggtgcgcttcctccagtgttggacacggctgcgcctacagaccctt
cctcctgtcccacttgcacagaagtactttgaacttttccctcaggagcgaagccccctt
tggcagaatccctgtgatgacaagaggcacaaagatatctggtccaaggagaaaacctgt
gatcgtctcccgaagttcctcattgtgggaccccagaaaacagggactacagctattcac
ttcttcctgagcctgcacccagctgtaactagcagcttccctagccccagcacatttgag
gagattcagttcttcaacagccctaattaccacaagggtattgactggtacatggatttc
ttccctgttccttccaatgccagcactgatttcctatttgaaaaaagtgccacctacttt
gactctgaagttgtaccacggcggggggctgccctcctgccacgagccaagatcatcaca
gtgctcaccaaccctgctgacagggcctactcctggtaccagcatcagcgagcccatgga
gacccagttgctctgaactataccttctatcaggtgatttcagcctcctcccagacccct
ctggcactacgctccctgcagaaccgctgtcttgtccctggctactattctacccatcta
caacgctggctgacttactacccctctggacagttgctgattgtggatgggcaagagctg
cgtaccaacccagcagcctcaatggagagcatccagaagttcctgggtatcacacccttt
ctgaactacacacggaccctcaggtttgatgatgataagggattttggtgccagggactt
gaaggtggtaagactcgctgtctaggccggagcaaaggccggaggtatccagatatggac
actgagtcccgtcttttccttacggattttttccggaaccataatttggagttgtcgaag
ctgctgagccggcttggacagccagtgccctcgtggcttcgggaagaactgcagcattcc
agtctgggctga
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