KEGG   Homo sapiens (human): 8525
Entry
8525              CDS       T01001                                 
Symbol
DGKZ, DAGK5, DAGK6, DGK-ZETA, hDGKzeta
Name
(RefSeq) diacylglycerol kinase zeta
  KO
K00901  diacylglycerol kinase (ATP) [EC:2.7.1.107]
Organism
hsa  Homo sapiens (human)
Pathway
hsa00561  Glycerolipid metabolism
hsa00564  Glycerophospholipid metabolism
hsa01100  Metabolic pathways
hsa04070  Phosphatidylinositol signaling system
hsa04072  Phospholipase D signaling pathway
hsa05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09100 Metabolism
  09103 Lipid metabolism
   00561 Glycerolipid metabolism
    8525 (DGKZ)
   00564 Glycerophospholipid metabolism
    8525 (DGKZ)
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    8525 (DGKZ)
   04072 Phospholipase D signaling pathway
    8525 (DGKZ)
 09160 Human Diseases
  09161 Cancer: overview
   05231 Choline metabolism in cancer
    8525 (DGKZ)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.107  diacylglycerol kinase (ATP)
     8525 (DGKZ)
SSDB
Motif
Pfam: DAGK_acc DGKI DAGK_cat Ank_2 Ank Ank_4 Ank_3 C1_1 Ank_5
Other DBs
NCBI-GeneID: 8525
NCBI-ProteinID: NP_001186196
OMIM: 601441
HGNC: 2857
Ensembl: ENSG00000149091
UniProt: Q13574
Structure
LinkDB
Position
11:46332926..46380554
AA seq 928 aa
MEPRDGSPEARSSDSESASASSSGSERDAGPEPDKAPRRLNKRRFPGLRLFGHRKAITKS
GLQHLAPPPPTPGAPCSESERQIRSTVDWSESATYGEHIWFETNVSGDFCYVGEQYCVAR
MLKSVSRRKCAACKIVVHTPCIEQLEKINFRCKPSFRESGSRNVREPTFVRHHWVHRRRQ
DGKCRHCGKGFQQKFTFHSKEIVAISCSWCKQAYHSKVSCFMLQQIEEPCSLGVHAAVVI
PPTWILRARRPQNTLKASKKKKRASFKRKSSKKGPEEGRWRPFIIRPTPSPLMKPLLVFV
NPKSGGNQGAKIIQSFLWYLNPRQVFDLSQGGPKEALEMYRKVHNLRILACGGDGTVGWI
LSTLDQLRLKPPPPVAILPLGTGNDLARTLNWGGGYTDEPVSKILSHVEEGNVVQLDRWD
LHAEPNPEAGPEDRDEGATDRLPLDVFNNYFSLGFDAHVTLEFHESREANPEKFNSRFRN
KMFYAGTAFSDFLMGSSKDLAKHIRVVCDGMDLTPKIQDLKPQCVVFLNIPRYCAGTMPW
GHPGEHHDFEPQRHDDGYLEVIGFTMTSLAALQVGGHGERLTQCREVVLTTSKAIPVQVD
GEPCKLAASRIRIALRNQATMVQKAKRRSAAPLHSDQQPVPEQLRIQVSRVSMHDYEALH
YDKEQLKEASVPLGTVVVPGDSDLELCRAHIERLQQEPDGAGAKSPTCQKLSPKWCFLDA
TTASRFYRIDRAQEHLNYVTEIAQDEIYILDPELLGASARPDLPTPTSPLPTSPCSPTPR
SLQGDAAPPQGEELIEAAKRNDFCKLQELHRAGGDLMHRDEQSRTLLHHAVSTGSKDVVR
YLLDHAPPEILDAVEENGETCLHQAAALGQRTICHYIVEAGASLMKTDQQGDTPRQRAEK
AQDTELAAYLENRQHYQMIQREDQETAV
NT seq 2787 nt   +upstreamnt  +downstreamnt
atggagccgcgggacggtagccccgaggcccggagcagcgactccgagtcggcttccgcc
tcgtccagcggctccgagcgcgacgccggtcccgagccggacaaggcgccgcggcgactc
aacaagcggcgcttcccggggctgcggctcttcgggcacaggaaagccatcaccaagtcg
ggcctccagcacctggccccccctccgcccacccctggggccccgtgcagcgagtcagag
cggcagatccggagtacagtggactggagcgagtcagcgacatatggggagcacatctgg
ttcgagaccaacgtgtccggggacttctgctacgttggggagcagtactgtgtagccagg
atgctgaagtcagtgtctcgaagaaagtgcgcagcctgcaagattgtggtgcacacgccc
tgcatcgagcagctggagaagataaatttccgctgtaagccgtccttccgtgaatcaggc
tccaggaatgtccgcgagccaacctttgtacggcaccactgggtacacagacgacgccag
gacggcaagtgtcggcactgtgggaagggattccagcagaagttcaccttccacagcaag
gagattgtggccatcagctgctcgtggtgcaagcaggcataccacagcaaggtgtcctgc
ttcatgctgcagcagatcgaggagccgtgctcgctgggggtccacgcagccgtggtcatc
ccgcccacctggatcctccgcgcccggaggccccagaatactctgaaagcaagcaagaag
aagaagagggcatccttcaagaggaagtccagcaagaaagggcctgaggagggccgctgg
agacccttcatcatcaggcccaccccctccccgctcatgaagcccctgctggtgtttgtg
aaccccaagagtgggggcaaccagggtgcaaagatcatccagtctttcctctggtatctc
aatccccgacaagtcttcgacctgagccagggagggcccaaggaggcgctggagatgtac
cgcaaagtgcacaacctgcggatcctggcgtgcgggggcgacggcacggtgggctggatc
ctctccaccctggaccagctacgcctgaagccgccaccccctgttgccatcctgcccctg
ggtactggcaacgacttggcccgaaccctcaactggggtgggggctacacagatgagcct
gtgtccaagatcctctcccacgtggaggaggggaacgtggtacagctggaccgctgggac
ctccacgctgagcccaaccccgaggcagggcctgaggaccgagatgaaggcgccaccgac
cggttgcccctggatgtcttcaacaactacttcagcctgggctttgacgcccacgtcacc
ctggagttccacgagtctcgagaggccaacccagagaaattcaacagccgctttcggaat
aagatgttctacgccgggacagctttctctgacttcctgatgggcagctccaaggacctg
gccaagcacatccgagtggtgtgtgatggaatggacttgactcccaagatccaggacctg
aaaccccagtgtgttgttttcctgaacatccccaggtactgtgcgggcaccatgccctgg
ggccaccctggggagcaccacgactttgagccccagcggcatgacgacggctacctcgag
gtcattggcttcaccatgacgtcgttggccgcgctgcaggtgggcggacacggcgagcgg
ctgacgcagtgtcgcgaggtggtgctcaccacatccaaggccatcccggtgcaggtggat
ggcgagccctgcaagcttgcagcctcacgcatccgcatcgccctgcgcaaccaggccacc
atggtgcagaaggccaagcggcggagcgccgcccccctgcacagcgaccagcagccggtg
ccagagcagttgcgcatccaggtgagtcgcgtcagcatgcacgactatgaggccctgcac
tacgacaaggagcagctcaaggaggcctctgtgccgctgggcactgtggtggtcccagga
gacagtgacctagagctctgccgtgcccacattgagagactccagcaggagcccgatggt
gctggagccaagtccccgacatgccagaaactgtcccccaagtggtgcttcctggacgcc
accactgccagccgcttctacaggatcgaccgagcccaggagcacctcaactatgtgact
gagatcgcacaggatgagatttatatcctggaccctgagctgctgggggcatcggcccgg
cctgacctcccaacccccacttcccctctccccacctcaccctgctcacccacgccccgg
tcactgcaaggggatgctgcaccccctcaaggtgaagagctgattgaggctgccaagagg
aacgacttctgtaagctccaggagctgcaccgagctgggggcgacctcatgcaccgagac
gagcagagtcgcacgctcctgcaccacgcagtcagcactggcagcaaggatgtggtccgc
tacctgctggaccacgcccccccagagatccttgatgcggtggaggaaaacggggagacc
tgtttgcaccaagcagcggccctgggccagcgcaccatctgccactacatcgtggaggcc
ggggcctcgctcatgaagacagaccagcagggcgacactccccggcagcgggctgagaag
gctcaggacaccgagctggccgcctacctggagaaccggcagcactaccagatgatccag
cgggaggaccaggagacggctgtgtag

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