Homo sapiens (human): 8527
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Entry
8527 CDS
T01001
Symbol
DGKD, DGK-delta, DGKdelta, dgkd-2
Name
(RefSeq) diacylglycerol kinase delta
KO
K00901
diacylglycerol kinase (ATP) [EC:
2.7.1.107
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00561
Glycerolipid metabolism
hsa00564
Glycerophospholipid metabolism
hsa01100
Metabolic pathways
hsa04070
Phosphatidylinositol signaling system
hsa04072
Phospholipase D signaling pathway
hsa05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09103 Lipid metabolism
00561 Glycerolipid metabolism
8527 (DGKD)
00564 Glycerophospholipid metabolism
8527 (DGKD)
09130 Environmental Information Processing
09132 Signal transduction
04070 Phosphatidylinositol signaling system
8527 (DGKD)
04072 Phospholipase D signaling pathway
8527 (DGKD)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
8527 (DGKD)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.107 diacylglycerol kinase (ATP)
8527 (DGKD)
BRITE hierarchy
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
DAGK_acc
DGKD_4H
DAGK_cat
SAM_2
C1_1
SAM_1
PH
PH_3
PH_8
C1_2
PH_11
SBE2_N
Motif
Other DBs
NCBI-GeneID:
8527
NCBI-ProteinID:
NP_690618
OMIM:
601826
HGNC:
2851
Ensembl:
ENSG00000077044
UniProt:
Q16760
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:233354494..233472098
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AA seq
1214 aa
AA seq
DB search
MAAAAGAPPPGPPQPPPPPPPEESSDSEPEAEPGSPQKLIRKVSTSGQIRQKTIIKEGML
TKQNNSFQRSKRRYFKLRGRTLYYAKTAKSIIFDEVDLTDASVAESSTKNVNNSFTVITP
CRKLILCADNRKEMEDWIAALKTVQNREHFEPTQYSMDHFSGMHNWYACSHARPTYCNVC
REALSGVTSHGLSCEVCKFKAHKRCAVRATNNCKWTTLASIGKDIIEDADGIAMPHQWLE
GNLPVSAKCTVCDKTCGSVLRLQDWRCLWCKAMVHTSCKESLLTKCPLGLCKVSVIPPTA
LNSIDSDGFWKASCPPSCTSPLLVFVNSKSGDNQGVKFLRRFKQLLNPAQVFDLMNGGPH
LGLRLFQKFDTFRILVCGGDGSVGWVLSEIDSLNLHKQCQLGVLPLGTGNDLARVLGWGS
ACDDDTQLPQILEKLERASTKMLDRWSVMAYEAKLPRQASSSTVTEDFSEDSEVQQILFY
EDSVAAHLSKILTSDQHSVVISSAKVLCETVKDFVARVGKAYEKTTESSEESEVMAKKCS
VLKEKLDSLLKTLDDESQASSSLPNPPPTIAEEAEDGDGSGSICGSTGDRLVASACPARP
QIFRPREQLMLRANSLKKAIRQIIEHTEKAVDEQNAQTQEQEGFVLGLSESEEKMDHRVC
PPLSHSESFGVPKGRSQRKVSKSPCEKLISKGSLSLGSSASLPPQPGSRDGLPALNTKIL
YPNVRAGMSGSLPGGSVISRLLINADPFNSEPETLEYYTEKCVMNNYFGIGLDAKISLDF
NNKRDEHPEKCRSRTKNMMWYGVLGTKELLHRTYKNLEQKVLLECDGRPIPLPSLQGIAV
LNIPSYAGGTNFWGGTKEDDTFAAPSFDDKILEVVAVFGSMQMAVSRVIRLQHHRIAQCR
TVKISILGDEGVPVQVDGEAWVQPPGYIRIVHKNRAQTLTRDRAFESTLKSWEDKQKCEL
PRPPSCSLHPEMLSEEEATQMDQFGQAAGVLIHSIREIAQSHRDMEQELAHAVNASSKSM
DRVYGKPRTTEGLNCSFVLEMVNNFRALRSETELLLSGKMALQLDPPQKEQLGSALAEMD
RQLRRLADTPWLCQSAEPGDEESVMLDLAKRSRSGKFRLVTKFKKEKNNKNKEAHSSLGA
PVHLWGTEEVAAWLEHLSLCEYKDIFTRHDIRGSELLHLERRDLKDLGVTKVGHMKRILC
GIKELSRSAPAVEA
NT seq
3645 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcgggcgcccctccgccgggtcccccgcaaccgcctccgccgccgccg
cccgaggagtcgtccgacagcgagcccgaggcggagcccggctccccacagaagctcatc
cgcaaggtgtccacgtcgggtcagatccgacagaagaccatcatcaaagaggggatgctg
accaaacagaacaattcattccagcgatcaaaaaggagatactttaagcttcgagggcga
acgctttactatgccaaaacggcaaagtcaatcatatttgatgaggtggatctgacagat
gccagcgtagctgaatccagtaccaaaaacgtcaacaacagttttacggtcataactcca
tgcaggaagctcatcttgtgtgctgataacagaaaagaaatggaagattggattgcagca
ttaaagactgtgcagaacagggagcactttgagcccacccagtacagcatggaccacttc
tcagggatgcacaattggtacgcctgttcccacgcgaggccgacctactgcaatgtgtgc
cgtgaggctctgtctggggtcacgtcgcacgggctgtcctgcgaggtgtgcaaatttaag
gcccacaagcgctgtgctgtgcgtgcaaccaataactgcaagtggaccacactggcctcg
atcgggaaggacatcattgaagatgcagatgggattgcaatgccccaccagtggttggaa
ggaaacctacctgtgagcgccaagtgcactgtgtgcgacaagacctgtggcagtgtgctg
cgcctgcaggactggcgctgcctctggtgcaaggccatggttcacacatcgtgtaaagaa
tccttgctgaccaagtgcccacttggcctgtgcaaagtgtcagtcatcccacccacggct
ctcaacagcatcgactccgatgggttctggaaggccagctgtcctccttcttgcacaagc
ccactgttggtcttcgtcaattcaaaaagtggggacaaccagggtgtgaagttcctcaga
agattcaaacagctactaaaccccgcccaggtcttcgacctcatgaacggaggcccacac
ctcggcttacggttattccagaagtttgacacattccggattctggtttgtggcggggat
ggaagtgttggctgggtcctctccgaaatcgacagcctcaaccttcataaacagtgtcag
ctgggagtgctgccgctcggcacagggaacgacttggcccgagtactgggctggggctca
gcctgcgatgacgacacccagctcccccagatcttggagaagttggagagagccagcacc
aagatgctggacaggtggagcgtcatggcatacgaggccaagctcccccggcaggcctcc
tcctctaccgtcaccgaagacttcagcgaggattccgaggtacagcagattctcttctat
gaagactcggttgcagcccacctttctaaaatcctcacctcggaccagcactcggtggtc
atctcctcggccaaagtgctctgtgagacggtgaaggacttcgtggcacgggtggggaag
gcctatgagaagacgaccgagagctcggaggagtcagaggtcatggccaagaagtgctct
gtcctgaaagagaagctggattcccttctcaagaccttggacgatgagtcccaggcctcg
tcctctctgcccaacccgccccccaccattgccgaggaggctgaagatggagatgggtcg
ggcagcatctgcggttccaccggagaccgcttggtggcatcagcttgcccggcccggccg
cagatattccggcctcgagaacagctcatgctgagagccaacagcctgaagaaagcaatt
cgtcagatcatagaacacacagaaaaagctgtcgatgagcagaatgcccagacccaggag
caggagggcttcgtcctgggcctctctgagtcagaggagaagatggaccacagagtgtgc
ccaccactgtcccacagcgagagcttcggggtccccaaggggaggagccagcgcaaagtg
tcgaaatctccgtgtgaaaagctgatcagcaaagggagtctgtccctaggcagttctgct
tcccttccgccccagccgggaagccgggacggcctgcctgcgctcaacaccaagatcctg
tacccaaatgtccgggctggaatgtctggttccttacccggtggctcagtcatcagtcgc
ctgttaattaatgctgatcccttcaactctgaaccagaaaccctagagtattacacggag
aaatgtgtcatgaacaactattttggcattggcctggatgcgaagatatccctggacttt
aacaacaagcgcgatgagcacccagagaagtgcaggagccgaaccaagaacatgatgtgg
tatggagttcttggaaccaaagagttgctgcacagaacctacaagaacctggagcaaaag
gtcttgctggagtgtgacgggcgacccatcccactccccagtcttcagggaattgctgtc
cttaacattcccagctatgccggaggaaccaacttctgggggggtaccaaggaagatgat
actttcgcagctccatcattcgatgacaagattctggaggtggtcgccgtgttcggcagc
atgcagatggccgtctctcgagtcatcaggctacagcatcatcggatcgcccagtgtcgc
acggtgaagatctccatccttggggatgagggcgtgcctgtgcaggtggacggagaggcc
tgggtccagccgccagggtacattcggattgtccacaagaaccgggcacagacactgacc
agagacagggcatttgagagcaccctgaagtcctgggaagacaagcagaagtgcgagctg
ccccgccctccatcctgttccctgcacccggagatgctgtccgaggaggaggccacccag
atggaccagtttgggcaggcagcaggggtcctcattcacagtatccgagaaatagctcag
tctcaccgggacatggagcaggaactggcccacgccgtcaatgccagctccaagtccatg
gaccgtgtgtatggcaagcccagaaccacagaggggctcaactgcagcttcgtcctggaa
atggtgaataacttcagagctctgcgcagtgagacggagctgctgctgtctgggaagatg
gccctgcagctggatccgcctcagaaggagcagctggggagtgctcttgccgagatggac
cgacagctcaggaggctggcagacaccccgtggctctgccagtccgcagagcccggcgac
gaagagagtgtgatgctggatcttgccaagcgcagtcgcagtggtaaattccgcctcgtg
accaagtttaaaaaggagaaaaacaacaagaacaaagaagctcacagtagcctgggagcc
ccggttcacctctgggggacagaggaggttgctgcctggctggagcacctcagtctctgt
gagtataaggacatcttcacacggcacgacatccggggctctgagctcctgcacctggag
cggagggacctcaaggacctgggcgtgaccaaggtgggccacatgaagaggatcctgtgt
ggcatcaaggagctgagccgcagcgcccccgccgtcgaggcctag
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