Homo sapiens (human): 8546
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Entry
8546 CDS
T01001
Symbol
AP3B1, ADTB3, ADTB3A, HPS, HPS2, PE
Name
(RefSeq) AP-3 complex subunit beta-1 isoform 1
KO
K12397
AP-3 complex subunit beta
Organism
hsa
Homo sapiens (human)
Pathway
hsa04142
Lysosome biogenesis
Network
nt06550
Lysosome biogenesis
Element
N02018
LAMP1 transport from the endosome to the lysosome
N02019
CD63 or TYRP1 transport from the endosome to the lysosome-related organelles (LROs)
N02020
GCase transport from the ER to the lysosome
Disease
H00166
Hermansky-Pudlak syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome biogenesis
8546 (AP3B1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
8546 (AP3B1)
Membrane trafficking [BR:
hsa04131
]
Endosome - Lysosome transport
Others
AP-3 complex
8546 (AP3B1)
Endosome - Golgi transport
8546 (AP3B1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Adaptin_N
AP3B1_C
SEEEED
AP3B1_C_2
Cnd1
HEAT_2
INTS1_R4
HEAT_GCN1
Motif
Other DBs
NCBI-GeneID:
8546
NCBI-ProteinID:
NP_003655
OMIM:
603401
HGNC:
566
Ensembl:
ENSP00000255194.7
UniProt:
O00203
A0A0S2Z5J4
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:complement(78000522..78294698)
Genome browser
AA seq
1094 aa
AA seq
DB search
MSSNSFPYNEQSGGGEATELGQEATSTISPSGAFGLFSSDLKKNEDLKQMLESNKDSAKL
DAMKRIVGMIAKGKNASELFPAVVKNVASKNIEIKKLVYVYLVRYAEEQQDLALLSISTF
QRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASADLSPYVRKNAAHAIQKLYSL
DPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCPDRIDLIHKNYRKLCNLLVDVEEWG
QVVIIHMLTRYARTQFVSPWKEGDELEDNGKNFYESDDDQKEKTDKKKKPYTMDPDHRLL
IRNTKPLLQSRNAAVVMAVAQLYWHISPKSEAGIISKSLVRLLRSNREVQYIVLQNIATM
SIQRKGMFEPYLKSFYVRSTDPTMIKTLKLEILTNLANEANISTLLREFQTYVKSQDKQF
AAATIQTIGRCATNILEVTDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEII
KHMAKLLDSITVPVARASILWLIGENCERVPKIAPDVLRKMAKSFTSEDDLVKLQILNLG
AKLYLTNSKQTKLLTQYILNLGKYDQNYDIRDRTRFIRQLIVPNVKSGALSKYAKKIFLA
QKPAPLLESPFKDRDHFQLGTLSHTLNIKATGYLELSNWPEVAPDPSVRNVEVIELAKEW
TPAGKAKQENSAKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDS
SSEQDSESGRESGLENKRTAKRNSKAKGKSDSEDGEKENEKSKTSDSSNDESSSIEDSSS
DSESESEPESESESRRVTKEKEKKTKQDRTPLTKDVSLLDLDDFNPVSTPVALPTPALSP
SLMADLEGLHLSTSSSVISVSTPAFVPTKTHVLLHRMSGKGLAAHYFFPRQPCIFGDKMV
SIQITLNNTTDRKIENIHIGEKKLPIGMKMHVFNPIDSLEPEGSITVSMGIDFCDSTQTA
SFQLCTKDDCFNVNIQPPVGELLLPVAMSEKDFKKEQGVLTGMNETSAVIIAAPQNFTPS
VIFQKVVNVANVGAVPSGQDNIHRFAAKTVHSGSLMLVTVELKEGSTAQLIINTEKTVIG
SVLLRELKPVLSQG
NT seq
3285 nt
NT seq
+upstream
nt +downstream
nt
atgtccagcaatagttttccttacaatgagcagtccggaggaggggaggcgacggagctg
ggtcaggaggcgacctcaaccatttccccctcgggggccttcggcctctttagcagcgat
ttgaagaagaatgaagatctaaagcaaatgttagagagcaacaaagattctgctaaactg
gatgctatgaagcggattgttgggatgattgcaaaagggaaaaatgcatctgaactgttt
cctgctgttgtgaagaatgtggccagtaaaaatattgagatcaagaagttggtatatgtt
tacctggttcgatatgctgaagaacagcaggatcttgcactcctgtccataagcactttt
cagcgagctctgaaggacccaaaccaactaattcgtgcaagcgctttgagagttctgtca
agtattagagtgccaattattgtacctatcatgatgcttgctattaaggaagcttctgct
gacttatcaccatatgttaggaagaatgcagcccatgcaatacaaaaattatacagcctt
gatccagagcagaaggaaatgttaattgaagtaattgaaaaacttctgaaagataaaagc
acattggtagctggcagtgttgtgatggcttttgaagaagtatgcccggacagaatagat
ctgattcataaaaattaccgcaagctatgtaacttactagtggatgttgaagagtggggg
caggttgtcataatccacatgctaactcgatatgctcggacacagtttgtcagcccttgg
aaagagggtgatgaattagaagacaatggaaagaatttctacgaatctgatgatgatcag
aaggaaaagactgacaaaaagaagaagccgtatactatggatccagatcatagactctta
attagaaatacaaagcctttgcttcagagcaggaatgctgcggtggttatggcagttgct
cagctgtattggcacatatcaccaaaatctgaagctggcataatttctaaatcactagtg
cgtttacttcgtagcaatagggaggtgcagtatattgtcctacaaaatatagcaactatg
tcaattcaaagaaaggggatgtttgaaccttatctgaagagtttctatgttaggtcaact
gatccaactatgatcaagacactgaagcttgaaattttgacaaacttggcaaatgaagcc
aacatatcaactcttcttcgagaatttcagacctatgtgaaaagccaggataaacaattt
gcagcagccactattcagactataggcagatgtgcaaccaacatcttggaagtcactgac
acgtgcctcaatggcttggtctgtctgctgtccaacagggatgaaatagttgttgctgaa
agtgtggttgttataaagaaattactgcaaatgcaacctgcacaacatggtgaaattatt
aaacatatggccaaactcctggacagtatcactgttcctgttgctagagcaagtattctt
tggctaattggagaaaactgtgaacgagttcctaaaattgcccctgatgttttgaggaag
atggctaaaagcttcactagtgaagatgatctggtaaaactgcagatattaaatctggga
gcaaaattgtatttaaccaactccaaacagacaaaattgcttacccagtacatattaaat
ctcggcaagtatgatcaaaactacgacatcagagaccgtacaagatttattaggcagctt
attgttccgaatgtaaagagtggagctttaagtaaatatgccaaaaaaatattcctagca
caaaagcctgcaccactgcttgagtctccttttaaagatagagatcatttccagcttggc
accttatctcatactctcaacattaaagctactgggtacctggaattatctaattggcca
gaggtggcgcccgacccatcagttcgaaatgtagaagtaatagagttggcaaaagaatgg
accccagcaggaaaagcaaagcaagagaattctgctaagaagttttattctgaatctgag
gaagaggaggactcttctgatagtagcagtgacagtgagagtgaatctggaagtgaaagt
ggagaacaaggcgaaagtggggaggaaggagacagcaatgaggacagcagtgaggactcc
tccagtgagcaggacagtgagagtggacgggagtcaggcctagaaaacaaaagaacagcc
aagaggaactcaaaagccaaaggaaaaagtgattctgaagatggggagaaggaaaatgaa
aaatctaaaacttcagattcttcaaatgacgaatctagttcaatagaagacagttcttcc
gattctgaatcagagtcagaacctgaaagtgaatctgaatccagaagagtcactaaggag
aaagaaaagaaaacaaagcaagatagaactcctcttaccaaagatgtttcacttctagat
ctggatgattttaacccagtatccactccagttgcacttcccacaccagctctttctcca
agtttgatggctgatcttgaaggtttacacttgtcaacttcctcttcagtcatcagtgtc
agtactcctgcatttgtaccaacgaaaactcacgtgctgcttcatcgaatgagtggaaaa
ggactagctgcccattatttctttccaagacagccttgcatttttggtgataagatggtc
tctatacaaataacactgaataacactactgatcgaaagatagaaaatatccacataggg
gaaaaaaaacttcctataggcatgaaaatgcatgtttttaatccaatagactctcttgag
cctgagggatccattacagtttcaatgggtattgacttttgtgattctactcagactgcc
agtttccagttgtgtaccaaggatgattgcttcaatgttaatattcagccacctgttgga
gaactgcttttacctgtggccatgtcagagaaagattttaagaaagagcaaggagtgcta
acaggaatgaatgaaacttctgctgtaatcattgctgcaccacagaatttcactccctct
gtgatctttcagaaggttgtaaatgtagccaatgtaggtgcagtcccttctggccaggat
aatatacacaggtttgcagctaaaactgtgcacagtgggtcattgatgctagtcacagtg
gaactgaaggaaggctctacagcccagcttatcataaacactgagaaaactgtgattggc
tctgttctgctgcgggaactgaagcctgtcctgtctcaggggtaa
DBGET
integrated database retrieval system
