Homo sapiens (human): 8726
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Entry
8726 CDS
T01001
Symbol
EED, COGIS, HEED, WAIT1
Name
(RefSeq) embryonic ectoderm development
KO
K11462
polycomb protein EED
Organism
hsa
Homo sapiens (human)
Pathway
hsa03083
Polycomb repressive complex
Network
nt06523
Epigenetic regulation by Polycomb complexes
Element
N01577
Gene silencing by methylation of H3K27 and ubiquitination of H2AK119
N01586
Activation of PRC2.2 by ubiquitination of H2AK119
N01614
Activation of PRC2.2 by ubiquitination of H2AK119 in germline genes
Disease
H02477
Cohen-Gibson syndrome
Drug target
Pociredir:
D12782
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
8726 (EED)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
hsa03036
]
8726 (EED)
Chromosome and associated proteins [BR:
hsa03036
]
Eukaryotic type
Histone modification proteins
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
8726 (EED)
PRC2.2
8726 (EED)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
WD40
Nup160
NBCH_WD40
Motif
Other DBs
NCBI-GeneID:
8726
NCBI-ProteinID:
NP_003788
OMIM:
605984
HGNC:
3188
Ensembl:
ENSG00000074266
UniProt:
O75530
Structure
PDB
LinkDB
All DBs
Position
11:86244753..86287615
Genome browser
AA seq
441 aa
AA seq
DB search
MSEREVSTAPAGTDMPAAKKQKLSSDENSNPDLSGDENDDAVSIESGTNTERPDTPTNTP
NAPGRKSWGKGKWKSKKCKYSFKCVNSLKEDHNQPLFGVQFNWHSKEGDPLVFATVGSNR
VTLYECHSQGEIRLLQSYVDADADENFYTCAWTYDSNTSHPLLAVAGSRGIIRIINPITM
QCIKHYVGHGNAINELKFHPRDPNLLLSVSKDHALRLWNIQTDTLVAIFGGVEGHRDEVL
SADYDLLGEKIMSCGMDHSLKLWRINSKRMMNAIKESYDYNPNKTNRPFISQKIHFPDFS
TRDIHRNYVDCVRWLGDLILSKSCENAIVCWKPGKMEDDIDKIKPSESNVTILGRFDYSQ
CDIWYMRFSMDFWQKMLALGNQVGKLYVWDLEVEDPHKAKCTTLTHHKCGAAIRQTSFSR
DSSILIAVCDDASIWRWDRLR
NT seq
1326 nt
NT seq
+upstream
nt +downstream
nt
atgtccgagagggaagtgtcgactgcgccggcgggaacagacatgcctgcggccaagaag
cagaagctgagcagtgacgagaacagcaatccagacctctctggagacgagaatgatgac
gctgtcagtatagaaagtggtacaaacactgaacgccctgatacacctacaaacacgcca
aatgcacctggaaggaaaagttggggaaagggaaaatggaagtcaaagaaatgcaaatat
tctttcaaatgtgtaaatagtctcaaggaagatcataaccaaccattgtttggagttcag
tttaactggcacagtaaagaaggagatccattagtgtttgcaactgtaggaagcaacaga
gttaccttgtatgaatgtcattcacaaggagaaatccggttgttgcaatcttacgtggat
gctgatgctgatgaaaacttttacacttgtgcatggacctatgatagcaatacgagccat
cctctgctggctgtagctggatctagaggcataattaggataataaatcctataacaatg
cagtgtataaagcactatgttggccatggaaatgctatcaatgagctgaaattccatcca
agagatccaaatcttctcctgtcagtaagtaaagatcatgctttacgattatggaatatc
cagacggacactctggtggcaatatttggaggcgtagaagggcacagagatgaagttcta
agtgctgattatgatcttttgggtgaaaaaataatgtcctgtggtatggatcattctctt
aaactttggaggatcaattcaaagagaatgatgaatgcaattaaggaatcttatgattat
aatccaaataaaactaacaggccatttatttctcagaaaatccattttcctgatttttct
accagagacatacataggaattatgttgattgtgtgcgatggttaggcgatttgatactt
tctaagtcttgtgaaaatgccattgtgtgctggaaacctggcaagatggaagatgatata
gataaaattaaacccagtgaatctaatgtgactattcttgggcgatttgattacagccag
tgtgacatttggtacatgaggttttctatggatttctggcaaaagatgcttgcattgggc
aatcaagttggcaaactttatgtttgggatttagaagtagaagatcctcataaagccaaa
tgtacaacactgactcatcataaatgtggtgctgctattcgacaaaccagttttagcagg
gatagcagcattcttatagctgtttgtgatgatgccagtatttggcgctgggatcgactt
cgataa
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