Homo sapiens (human): 8798
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Entry
8798 CDS
T01001
Symbol
DYRK4
Name
(RefSeq) dual specificity tyrosine phosphorylation regulated kinase 4
KO
K18669
dual specificity tyrosine-phosphorylation-regulated kinase 2/3/4 [EC:
2.7.12.1
]
Organism
hsa
Homo sapiens (human)
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
8798 (DYRK4)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.1 dual-specificity kinase
8798 (DYRK4)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CMGC group
DYRK family [OT]
8798 (DYRK4)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ABC1
Kinase-like
APH
DUF4606
Motif
Other DBs
NCBI-GeneID:
8798
NCBI-ProteinID:
NP_003836
OMIM:
609181
HGNC:
3095
Ensembl:
ENSG00000010219
UniProt:
Q9NR20
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All DBs
Position
12:4562208..4613875
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AA seq
520 aa
AA seq
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MPASELKASEIPFHPSIKTQDPKAEEKSPKKQKVTLTAAEALKLFKNQLSPYEQSEILGY
AELWFLGLEAKKLDTAPEKFSKTSFDDEHGFYLKVLHDHIAYRYEVLETIGKGSFGQVAK
CLDHKNNELVALKIIRNKKRFHQQALMELKILEALRKKDKDNTYNVVHMKDFFYFRNHFC
ITFELLGINLYELMKNNNFQGFSLSIVRRFTLSVLKCLQMLSVEKIIHCDLKPENIVLYQ
KGQASVKVIDFGSSCYEHQKVYTYIQSRFYRSPEVILGHPYDVAIDMWSLGCITAELYTG
YPLFPGENEVEQLACIMEVLGLPPAGFIQTASRRQTFFDSKGFPKNITNNRGKKRYPDSK
DLTMVLKTYDTSFLDFLRRCLVWEPSLRMTPDQALKHAWIHQSRNLKPQPRPQTLRKSNS
FFPSETRKDKVQGCHHSSRKADEITKETTEKTKDSPTKHVQHSGDQQDCLQHGADTVQLP
QLVDAPKKSEAAVGAEVSMTSPGQSKNFSLKNTNVLPPIV
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgccggcctcagagctcaaggcttcagaaatacctttccaccctagcattaaaacccag
gatcccaaggcagaggagaagtcaccaaagaagcaaaaggtgactctgacagcggcagag
gccctaaagctttttaagaaccagctgtctccatatgaacaaagtgaaatcctgggctac
gcggagctgtggttcctgggtcttgaagccaagaagctcgacacggctcctgagaaattt
agcaagacgagttttgatgatgagcatggcttctatctgaaggtcctgcatgatcacatt
gcctaccgctatgaagttctggagacaatcgggaaggggtcctttggacaggtggccaag
tgcttggatcacaaaaacaatgagctggtggccctgaaaatcatcaggaacaagaagagg
tttcaccagcaggccctgatggagctgaagatcctggaagctctcagaaagaaggacaaa
gacaacacctacaatgtggtgcatatgaaggactttttctactttcgcaatcacttctgc
atcacctttgagctcctgggaatcaacttgtatgagttgatgaagaataacaactttcaa
ggcttcagtctgtccatagttcggcgcttcactctctctgttttgaagtgcttgcagatg
ctttcggtagagaaaatcattcactgtgatctcaagcccgaaaatatagtgctataccaa
aagggccaagcctctgttaaagtcattgactttggatcaagctgttatgaacaccagaaa
gtatacacgtacatccaaagccggttctaccgatccccagaagtgatcctgggccacccc
tacgacgtggccattgacatgtggagcctgggctgcatcacggcggagttgtacacgggc
taccccctgttccccggggagaatgaggtggagcagctggcctgcatcatggaggtgctg
ggtctgccgccagccggcttcattcagacagcctccaggagacagacattctttgattcc
aaaggttttcctaaaaatataaccaacaacagggggaaaaaaagatacccagattccaag
gacctcacgatggtgctgaaaacctatgacaccagcttcctggactttctcagaaggtgt
ttggtatgggaaccttctcttcgcatgaccccggaccaggccctcaagcatgcttggatt
catcagtctcggaacctcaagccacagcccaggccccagaccctgaggaaatccaattcc
tttttcccctctgagacaaggaaggacaaggttcaaggctgtcatcactcgagcagaaaa
gcagatgagatcaccaaagagactacagagaaaacaaaagatagccccacgaagcatgtt
cagcattcaggtgatcagcaggactgtctccagcacggagctgacactgttcagctgcct
caactggtagacgctcccaagaagtcagaggcagctgtcggggcggaggtgtccatgacc
tccccaggacagagcaaaaacttctccctcaagaacacaaacgttttaccccctattgta
tga
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