KEGG   Homo sapiens (human): 8916
Entry
8916              CDS       T01001                                 
Symbol
HERC3
Name
(RefSeq) HECT and RLD domain containing E3 ubiquitin protein ligase 3
  KO
K10614  E3 ubiquitin-protein ligase HERC3 [EC:2.3.2.26]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04120  Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    8916 (HERC3)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:hsa04121]
    8916 (HERC3)
Enzymes [BR:hsa01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.26  HECT-type E3 ubiquitin transferase
     8916 (HERC3)
Ubiquitin system [BR:hsa04121]
 Ubiquitin ligases (E3)
  HECT type E3
   8916 (HERC3)
SSDB
Motif
Pfam: RCC1 HECT RCC1_2
Other DBs
NCBI-GeneID: 8916
NCBI-ProteinID: NP_055421
OMIM: 605200
HGNC: 4876
Ensembl: ENSG00000138641
Pharos: Q15034(Tdark)
UniProt: Q15034
LinkDB
Position
4:88523843..88708539
AA seq 1050 aa
MLCWGYWSLGQPGISTNLQGIVAEPQVCGFISDRSVKEVACGGNHSVFLLEDGEVYTCGL
NTKGQLGHEREGNKPEQIGALADQHIIHVACGESHSLALSDRGQLFSWGAGSDGQLGLMT
TEDSVAVPRLIQKLNQQTILQVSCGNWHCLALAADGQFFTWGKNSHGQLGLGKEFPSQAS
PQRVRSLEGIPLAQVAAGGAHSFALSLSGAVFGWGMNNAGQLGLSDEKDRESPCHVKLLR
TQKVVYISCGEEHTAVLTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIA
CGRQHTLAFVPSSGLIYAFGCGARGQLGTGHTCNVKCPSPVKGYWAAHSGQLSARADRFK
YHIVKQIFSGGDQTFVLCSKYENYSPAVDFRTMNQAHYTSLINDETIAVWRQKLSEHNNA
NTINGVVQILSSAACWNGSFLEKKIDEHFKTSPKIPGIDLNSTRVLFEKLMNSQHSMILE
QILNSFESCLIPQLSSSPPDVEAMRIYLILPEFPLLQDSKYYITLTIPLAMAILRLDTNP
SKVLDNWWSQVCPKYFMKLVNLYKGAVLYLLRGRKTFLIPVLFNNYITAALKLLEKLYKV
NLKVKHVEYDTFYIPEISNLVDIQEDYLMWFLHQAGMKARPSIIQDTVTLCSYPFIFDAQ
AKTKMLQTDAELQMQVAVNGANLQNVFMLLTLEPLLARSPFLVLHVRRNNLVGDALRELS
IHSDIDLKKPLKVIFDGEEAVDAGGVTKEFFLLLLKELLNPIYGMFTYYQDSNLLWFSDT
CFVEHNWFHLIGITCGLAIYNSTVVDLHFPLALYKKLLNVKPGLEDLKELSPTEGRSLQE
LLDYPGEDVEETFCLNFTICRESYGVIEQKKLIPGGDNVTVCKDNRQEFVDAYVNYVFQI
SVHEWYTAFSSGFLKVCGGKVLELFQPSELRAMMVGNSNYNWEELEETAIYKGDYSATHP
TVKLFWETFHEFPLEKKKKFLLFLTGSDRIPIYGMASLQIVIQSTASGEEYLPVAHTCYN
LLDLPKYSSKEILSARLTQALDNYEGFSLA
NT seq 3153 nt   +upstreamnt  +downstreamnt
atgttatgttggggatattggtctctgggccaacctggtatcagcaccaacctgcaggga
attgtggctgagccccaggtgtgtgggttcatatctgacagaagtgtcaaggaagtggcc
tgtgggggaaaccactctgtgttcctgctggaagatggggaagtttacacatgtggtttg
aacaccaaggggcaactgggccatgagagggaaggaaacaagccagaacaaattggagct
ctggcagatcagcatatcattcatgtggcatgtggcgagtcccacagtctggccctcagt
gaccgaggccagctgttttcttggggtgcagggagtgatggtcagctaggactcatgact
actgaggattctgtggcagtgcccaggttaatacaaaagctgaaccagcaaacaatatta
caagtttcctgtggcaactggcattgcttggctcttgcggctgatggccagttcttcacc
tggggaaagaacagccatgggcagcttggcttagggaaggagttcccctcccaagccagc
ccacagagggtgaggtccctggaggggatcccactggctcaggtggctgccggaggggct
cacagctttgccctgtctctctcaggagctgtttttggctgggggatgaataatgccggg
cagctagggctcagtgatgaaaaagatcgagaatctccatgccatgtaaaactcttacgc
acgcaaaaagttgtctatattagttgtggagaagaacacacagcagttctcacaaagagt
ggaggtgtgtttacctttggcgctggttcctgtgggcaacttggacacgactccatgaat
gatgaggttaaccctagaagagttctagagctgatgggtagtgaagtaactcaaattgct
tgtggcagacaacataccctagccttcgtgccttcttctggactcatctatgcatttggt
tgtggagcaagaggtcaattaggaactgggcacacttgtaatgttaagtgcccatctcct
gtcaagggttactgggctgcccacagtggccagctttcagcccgagctgatcgctttaaa
tatcatatcgttaagcagatcttctctggaggagaccagacttttgtactttgctccaaa
tacgagaattattctcctgctgttgacttcaggactatgaaccaagcacattataccagt
ttaataaatgatgaaaccatagcagtttggagacaaaaactctcagaacacaacaatgca
aatacaatcaatggtgttgttcagatattatcttctgcagcctgttggaatggaagtttt
cttgaaaaaaaaattgatgaacattttaaaacgagtcccaaaatccctgggattgacctg
aactcaactagggtgttatttgagaagttaatgaactctcagcactccatgattctagaa
cagattttgaacagttttgaaagttgtctgattccccagttgtcaagctcaccaccagat
gttgaagccatgagaatctatttaatactacctgagtttcccctactccaggattccaag
tattatataacattgactattcccttggctatggccattcttcggctggatacaaacccc
agcaaagtactagataactggtggtctcaggtatgcccgaaatatttcatgaagctggta
aacctctataaaggtgcagtcctttatctactgaggggaagaaagacattcttaattccc
gtactgtttaacaattatatcacagcagctctcaaactcttggagaagttatataaggta
aatcttaaagtgaagcatgtggaatatgatacattttacattcctgagatttccaatctc
gtggacattcaggaagactacctcatgtggttcttgcatcaagcagggatgaaggctaga
ccatcaataatacaggatactgtaacactttgttcctaccctttcatctttgatgcccaa
gccaagaccaaaatgttacagacagatgctgaactacagatgcaggtggcagtcaatgga
gccaacctgcagaatgtcttcatgcttctcaccctggagcctctgctggccagaagcccc
ttcctggtccttcacgttcgcaggaacaaccttgttggagatgccctaagagagctgagc
attcattctgatattgatttgaaaaagcctctcaaagtaatctttgatggtgaagaagca
gtggatgccggtggtgttacaaaggaattttttcttttgctgttaaaagaacttttgaat
cccatctatggaatgtttacctactatcaagattcaaatctcttgtggttttcagacacg
tgttttgtagagcacaactggtttcacttgattggtataacctgtggactagctatctac
aactccactgtggtcgatctccacttcccattggctctctacaagaagttactcaatgta
aagcctggcttggaagacttaaaggagttgtcacccactgaaggaaggagtctccaagag
cttttagattaccccggggaggatgtggaggagactttctgcctcaacttcacgatctgc
cgagaaagctatggagtgattgaacagaagaagctgatacctgggggagataatgtaact
gtgtgcaaggataacaggcaggaatttgtggatgcttatgtgaattatgtcttccaaatc
tcagttcatgaatggtacacagccttctctagtggcttcctaaaggtgtgtggtggcaaa
gtacttgagctcttccagccttcagaactgagggctatgatggtggggaacagcaactac
aactgggaagaactggaagagactgccatctacaagggagattactcggccacacatccc
actgtaaaactattttgggaaacatttcatgagtttccattggaaaagaagaagaagttt
ctcttgttcctgacaggcagcgatcggattcccatctacggcatggccagtctgcagatt
gtcatccagtccacagccagcggggaggagtacttgccggtggcccacacttgctacaac
cttcttgacctccccaagtacagcagcaaagagattctgagtgcccggctgacccaggcc
cttgacaactatgaagggtttagtttggcctga

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