Homo sapiens (human): 9039
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Entry
9039 CDS
T01001
Symbol
UBA3, NAE2, UBE1C, hUBA3
Name
(RefSeq) ubiquitin like modifier activating enzyme 3
KO
K10686
NEDD8-activating enzyme E1 [EC:
6.2.1.64
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
9039 (UBA3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
9039 (UBA3)
Enzymes [BR:
hsa01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.64 E1 NEDD8-activating enzyme
9039 (UBA3)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin-activating enzymes (E1)
UBL-activating enzymes
9039 (UBA3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ThiF
E2_bind
UAE_UbL
Shikimate_DH
Motif
Other DBs
NCBI-GeneID:
9039
NCBI-ProteinID:
NP_003959
OMIM:
603172
HGNC:
12470
Ensembl:
ENSG00000144744
UniProt:
Q8TBC4
Structure
PDB
LinkDB
All DBs
Position
3:complement(69054730..69080373)
Genome browser
AA seq
463 aa
AA seq
DB search
MADGEEPEKKRRRIEELLAEKMAVDGGCGDTGDWEGRWNHVKKFLERSGPFTHPDFEPST
ESLQFLLDTCKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQFLFRPKDI
GRPKAEVAAEFLNDRVPNCNVVPHFNKIQDFNDTFYRQFHIIVCGLDSIIARRWINGMLI
SLLNYEDGVLDPSSIVPLIDGGTEGFKGNARVILPGMTACIECTLELYPPQVNFPMCTIA
SMPRLPEHCIEYVRMLQWPKEQPFGEGVPLDGDDPEHIQWIFQKSLERASQYNIRGVTYR
LTQGVVKRIIPAVASTNAVIAAVCATEVFKIATSAYIPLNNYLVFNDVDGLYTYTFEAER
KENCPACSQLPQNIQFSPSAKLQEVLDYLTNSASLQMKSPAITATLEGKNRTLYLQSVTS
IEERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLHFTS
NT seq
1392 nt
NT seq
+upstream
nt +downstream
nt
atggcggatggcgaggagccggagaagaaaagaaggagaatagaggagctgctggctgag
aaaatggctgttgatggtgggtgtggggacactggagactgggaaggtcgctggaaccat
gtaaagaagttcctcgagcgatctggacccttcacacaccctgatttcgaaccgagcact
gaatctctccagttcttgttagatacatgtaaagttctagtcattggagctggcggctta
ggatgtgagctcctgaaaaatctggccttgtctggttttagacagattcatgttatagat
atggacactatagatgtttccaatctaaataggcagtttttatttaggcctaaagatatt
ggaagacctaaggctgaagttgctgcagaatttctaaatgacagagttcctaattgcaat
gtagttccacatttcaacaagattcaagattttaacgacactttctatcgacaatttcat
attattgtatgtggactggactctatcatcgccagaagatggataaatggcatgctgata
tctcttctaaattatgaagatggtgtcttagatccaagctccattgtccctttgatagat
ggggggacagaaggttttaaaggaaatgcccgggtgattctgcctggaatgactgcttgt
atcgaatgcacgctggaactttatccaccacaggttaattttcccatgtgcaccattgca
tctatgcccaggctaccagaacactgtattgagtatgtaaggatgttgcagtggcctaag
gagcagccttttggagaaggggttccattagatggagatgatcctgaacatatacaatgg
attttccaaaaatccctagagagagcatcacaatataatattaggggtgttacgtatagg
ctcactcaaggggtagtaaaaagaatcattcctgcagtagcttccacaaatgcagtcatt
gcagctgtgtgtgccactgaggtttttaaaatagccacaagtgcatacattcccttgaat
aattacttggtgtttaatgatgtagatgggctgtatacatacacatttgaagcagaaaga
aaggaaaactgcccagcttgtagccagcttcctcaaaatattcagttttctccatcagct
aaactacaggaggttttggattatctaaccaatagtgcttctctgcaaatgaaatctcca
gccatcacagccaccctagagggaaaaaatagaacactttacttacagtcggtaacctct
attgaagaacgaacaaggccaaatctctccaaaacattgaaagaattggggcttgttgat
ggacaagaactggcggttgctgatgtcaccaccccacagactgtactattcaaacttcat
tttacttcttaa
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