Homo sapiens (human): 9060
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Entry
9060 CDS
T01001
Symbol
PAPSS2, ATPSK2, BCYM4, SK2
Name
(RefSeq) 3'-phosphoadenosine 5'-phosphosulfate synthase 2
KO
K13811
3'-phosphoadenosine 5'-phosphosulfate synthase [EC:
2.7.7.4
2.7.1.25
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00230
Purine metabolism
hsa00450
Selenocompound metabolism
hsa00920
Sulfur metabolism
hsa01100
Metabolic pathways
hsa01320
Sulfur cycle
Disease
H00522
Brachyolmia
H00761
SEMD, Pakistani type
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09102 Energy metabolism
00920 Sulfur metabolism
9060 (PAPSS2)
09104 Nucleotide metabolism
00230 Purine metabolism
9060 (PAPSS2)
09106 Metabolism of other amino acids
00450 Selenocompound metabolism
9060 (PAPSS2)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
9060 (PAPSS2)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.25 adenylyl-sulfate kinase
9060 (PAPSS2)
2.7.7 Nucleotidyltransferases
2.7.7.4 sulfate adenylyltransferase
9060 (PAPSS2)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
APS_kinase
ATP-sulfurylase
PUA_2
AAA_33
AAA_18
PEPCK_ATP
RsgA_GTPase
DUF5474
Motif
Other DBs
NCBI-GeneID:
9060
NCBI-ProteinID:
NP_004661
OMIM:
603005
HGNC:
8604
Ensembl:
ENSG00000198682
UniProt:
O95340
Q5TB52
Structure
PDB
PDBj
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All DBs
Position
10:87659878..87747705
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AA seq
614 aa
AA seq
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MSGIKKQKTENQQKSTNVVYQAHHVSRNKRGQVVGTRGGFRGCTVWLTGLSGAGKTTISF
ALEEYLVSHAIPCYSLDGDNVRHGLNRNLGFSPGDREENIRRIAEVAKLFADAGLVCITS
FISPFAKDRENARKIHESAGLPFFEIFVDAPLNICESRDVKGLYKRARAGEIKGFTGIDS
DYEKPETPERVLKTNLSTVSDCVHQVVELLQEQNIVPYTIIKDIHELFVPENKLDHVRAE
AETLPSLSITKLDLQWVQVLSEGWATPLKGFMREKEYLQVMHFDTLLDDGVINMSIPIVL
PVSAEDKTRLEGCSKFVLAHGGRRVAILRDAEFYEHRKEERCSRVWGTTCTKHPHIKMVM
ESGDWLVGGDLQVLEKIRWNDGLDQYRLTPLELKQKCKEMNADAVFAFQLRNPVHNGHAL
LMQDTRRRLLERGYKHPVLLLHPLGGWTKDDDVPLDWRMKQHAAVLEEGVLDPKSTIVAI
FPSPMLYAGPTEVQWHCRSRMIAGANFYIVGRDPAGMPHPETKKDLYEPTHGGKVLSMAP
GLTSVEIIPFRVAAYNKAKKAMDFYDPARHNEFDFISGTRMRKLAREGENPPDGFMAPKA
WKVLTDYYRSLEKN
NT seq
1845 nt
NT seq
+upstream
nt +downstream
nt
atgtcggggatcaagaagcaaaagacggagaaccagcagaaatccaccaatgtagtctat
caggcccaccatgtgagcaggaataagagagggcaagtggttggaacaaggggtgggttc
cgaggatgtaccgtgtggctaacaggtctctctggtgctggaaaaacaacgataagtttt
gccctggaggagtaccttgtctcccatgccatcccttgttactccctggatggggacaat
gtccgtcatggccttaacagaaatctcggattctctcctggggacagagaggaaaatatc
cgccggattgctgaggtggctaagctgtttgctgatgctggtctggtctgcattaccagc
tttatttctccattcgcaaaggatcgtgagaatgcccgcaaaatacatgaatcagcaggg
ctgccattctttgaaatatttgtagatgcacctctaaatatttgtgaaagcagagacgta
aaaggcctctataaaagggccagagctggggagattaaaggatttacaggtattgattct
gattatgagaaacctgaaactcctgagcgtgtgcttaaaaccaatttgtccacagtgagt
gactgtgtccaccaggtagtggaacttctgcaagagcagaacattgtaccctatactata
atcaaagatatccacgaactctttgtgccggaaaacaaacttgaccacgtccgagctgag
gctgaaactctcccttcattatcaattactaagctggatctccagtgggtccaggttttg
agcgaaggctgggccactcccctcaaaggtttcatgcgggagaaggagtacttacaggtt
atgcactttgacaccctgctagatgatggcgtgatcaacatgagcatccccattgtactg
cccgtctctgcagaggataagacacggctggaagggtgcagcaagtttgtcctggcacat
ggtggacggagggtagctatcttacgagacgctgaattctatgaacacagaaaagaggaa
cgctgttcccgtgtttgggggacaacatgtacaaaacacccccatatcaaaatggtgatg
gaaagtggggactggctggttggtggagaccttcaggtgctggagaaaataagatggaat
gatgggctggaccaataccgtctgacacctctggagctcaaacagaaatgtaaagaaatg
aatgctgatgcggtgtttgcattccagttgcgcaatcctgtccacaatggccatgccctg
ttgatgcaggacactcgccgcaggctcctagagaggggctacaagcacccggtcctccta
ctacaccctctgggcggctggaccaaggatgacgatgtgcctctagactggcggatgaag
cagcacgcggctgtgctcgaggaaggggtcctggatcccaagtcaaccattgttgccatc
tttccgtctcccatgttatatgctggccccacagaggtccagtggcactgcaggtcccgg
atgattgcgggtgccaatttctacattgtggggagggaccctgcaggaatgccccatcct
gaaaccaagaaggatctgtatgaacccactcatgggggcaaggtcttgagcatggcccct
ggcctcacctctgtggaaatcattccattccgagtggctgcctacaacaaagccaaaaaa
gccatggacttctatgatccagcaaggcacaatgagtttgacttcatctcaggaactcga
atgaggaagctcgcccgggaaggagagaatcccccagatggcttcatggcccccaaagca
tggaaggtcctgacagattattacaggtccctggagaagaactaa
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