Homo sapiens (human): 9149
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Entry
9149 CDS
T01001
Symbol
DYRK1B, AOMS3, MIRK
Name
(RefSeq) dual specificity tyrosine phosphorylation regulated kinase 1B
KO
K08825
dual specificity tyrosine-phosphorylation-regulated kinase 1 [EC:
2.7.12.1
]
Organism
hsa
Homo sapiens (human)
Disease
H02384
Abdominal obesity-metabolic syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
9149 (DYRK1B)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
9149 (DYRK1B)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.1 dual-specificity kinase
9149 (DYRK1B)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: CMGC group
DYRK family [OT]
9149 (DYRK1B)
Membrane trafficking [BR:
hsa04131
]
Endocytosis
Clathrin-mediated endocytosis
Kinases
9149 (DYRK1B)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
APH
PTHB1_hp
Motif
Other DBs
NCBI-GeneID:
9149
NCBI-ProteinID:
NP_004705
OMIM:
604556
HGNC:
3092
Ensembl:
ENSG00000105204
UniProt:
Q9Y463
Structure
PDB
PDBj
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All DBs
Position
19:complement(39825350..39834162)
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AA seq
629 aa
AA seq
DB search
MAVPPGHGPFSGFPGPQEHTQVLPDVRLLPRRLPLAFRDATSAPLRKLSVDLIKTYKHIN
EVYYAKKKRRAQQAPPQDSSNKKEKKVLNHGYDDDNHDYIVRSGERWLERYEIDSLIGKG
SFGQVVKAYDHQTQELVAIKIIKNKKAFLNQAQIELRLLELMNQHDTEMKYYIVHLKRHF
MFRNHLCLVFELLSYNLYDLLRNTHFRGVSLNLTRKLAQQLCTALLFLATPELSIIHCDL
KPENILLCNPKRSAIKIVDFGSSCQLGQRIYQYIQSRFYRSPEVLLGTPYDLAIDMWSLG
CILVEMHTGEPLFSGSNEVDQMNRIVEVLGIPPAAMLDQAPKARKYFERLPGGGWTLRRT
KELRKDYQGPGTRRLQEVLGVQTGGPGGRRAGEPGHSPADYLRFQDLVLRMLEYEPAARI
SPLGALQHGFFRRTADEATNTGPAGSSASTSPAPLDTCPSSSTASSISSSGGSSGSSSDN
RTYRYSNRYCGGPGPPITDCEMNSPQVPPSQPLRPWAGGDVPHKTHQAPASASSLPGTGA
QLPPQPRYLGRPPSPTSPPPPELMDVSLVGGPADCSPPHPAPAPQHPAASALRTRMTGGR
PPLPPPDDPATLGPHLGLRGVPQSTAASS
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atggccgtcccaccgggccatggtcccttctctggcttcccagggccccaggagcacacg
caggtattgcctgatgtgcggctactgcctcggaggctgcccctggccttccgggatgca
acctcagccccgctgcgtaagctctctgtggacctcatcaagacctacaagcacatcaat
gaggtatactatgcgaagaagaagcggcgggcccagcaggcgccaccccaggattcgagc
aacaagaaggagaagaaggtcctgaaccatggttatgatgacgacaaccatgactacatc
gtgcgcagtggcgagcgctggctggagcgctacgaaattgactcgctcattggcaaaggc
tcctttggccaggtggtgaaagcctatgatcatcagacccaggagcttgtggccatcaag
atcatcaagaacaaaaaggctttcctgaaccaggcccagattgagctgcggctgctggag
ctgatgaaccagcatgacacggagatgaagtactatatagtacacctgaagcggcacttc
atgttccggaaccacctgtgcctggtatttgagctgctgtcctacaacctgtacgacctc
ctgcgcaacacccacttccgcggcgtctcgctgaacctgacccggaagctggcgcagcag
ctctgcacggcactgctctttctggccacgcctgagctcagcatcattcactgcgacctc
aagcccgaaaacatcttgctgtgcaaccccaagcgcagcgccatcaagattgtggacttc
ggcagctcctgccagcttggccagaggatctaccagtatatccagagccgcttctaccgc
tcacctgaggtgctcctgggcacaccctacgacctggccattgacatgtggtccctgggc
tgcatccttgtggagatgcacaccggagagcccctcttcagtggctccaatgaggtcgac
cagatgaaccgcattgtggaggtgctgggcatcccaccggccgccatgctggaccaggcg
cccaaggctcgcaagtactttgaacggctgcctgggggtggctggaccctacgaaggacg
aaagaactcaggaaggattaccagggccccgggacacggcggctgcaggaggtgctgggc
gtgcagacgggcgggcccgggggccggcgggcgggggagccgggccacagccccgccgac
tacctccgcttccaggacctggtgctgcgcatgctggagtatgagcccgccgcccgcatc
agccccctgggggctctgcagcacggcttcttccgccgcacggccgacgaggccaccaac
acgggcccggcaggcagcagtgcctccacctcgcccgcgcccctcgacacctgcccctct
tccagcaccgccagctccatctccagttctggaggctccagtggctcctccagtgacaac
cggacctaccgctacagcaaccgatattgtgggggccctgggccccctatcacagactgt
gagatgaacagcccccaggtcccaccctcccagccgctgcggccctgggcagggggtgat
gtgccccacaagacacatcaagcccctgcctctgcctcgtcactgcctgggaccggggcc
cagttacccccccagccccgataccttggtcgtcccccatcaccaacctcaccaccaccc
ccggagctgatggatgtgagcctggtgggcggccctgctgactgctccccacctcaccca
gcgcctgccccccagcacccggctgcctcagccctccggactcggatgactggaggtcgt
ccacccctcccgcctcctgatgaccctgccactctggggcctcacctgggcctccgtggt
gtaccccagagcacagcagccagctcgtga
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