Homo sapiens (human): 9320
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Entry
9320 CDS
T01001
Symbol
TRIP12, MRD49, TRIP-12, TRIPC, ULF
Name
(RefSeq) thyroid hormone receptor interactor 12
KO
K10590
E3 ubiquitin-protein ligase TRIP12 [EC:
2.3.2.26
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa04120
Ubiquitin mediated proteolysis
Disease
H00773
Autosomal dominant intellectual developmental disorder
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
9320 (TRIP12)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
hsa04121
]
9320 (TRIP12)
Enzymes [BR:
hsa01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
9320 (TRIP12)
Ubiquitin system [BR:
hsa04121
]
Ubiquitin ligases (E3)
HECT type E3
9320 (TRIP12)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WWE
HEAT_2
UNC45-central
Maestro_HEAT
Motif
Other DBs
NCBI-GeneID:
9320
NCBI-ProteinID:
NP_004229
OMIM:
604506
HGNC:
12306
Ensembl:
ENSG00000153827
Pharos:
Q14669
(Tbio)
UniProt:
Q14669
Structure
PDB
LinkDB
All DBs
Position
2:complement(229763837..229923186)
Genome browser
AA seq
1992 aa
AA seq
DB search
MSNRPNNNPGGSLRRSQRNTAGAQPQDDSIGGRSCSSSSAVIVPQPEDPDRANTSERQKT
GQVPKKDNSRGVKRSASPDYNRTNSPSSAKKPKALQHTESPSETNKPHSKSKKRHLDQEQ
QLKSAQSPSTSKAHTRKSGATGGSRSQKRKRTESSCVKSGSGSESTGAEERSAKPTKLAS
KSATSAKAGCSTITDSSSAASTSSSSSAVASASSTVPPGARVKQGKDQNKARRSRSASSP
SPRRSSREKEQSKTGGSSKFDWAARFSPKVSLPKTKLSLPGSSKSETSKPGPSGLQAKLA
SLRKSTKKRSESPPAELPSLRRSTRQKTTGSCASTSRRGSGLGKRGAAEARRQEKMADPE
SNQEAVNSSAARTDEAPQGAAGAVGMTTSGESESDDSEMGRLQALLEARGLPPHLFGPLG
PRMSQLFHRTIGSGASSKAQQLLQGLQASDESQQLQAVIEMCQLLVMGNEETLGGFPVKS
VVPALITLLQMEHNFDIMNHACRALTYMMEALPRSSAVVVDAIPVFLEKLQVIQCIDVAE
QALTALEMLSRRHSKAILQAGGLADCLLYLEFFSINAQRNALAIAANCCQSITPDEFHFV
ADSLPLLTQRLTHQDKKSVESTCLCFARLVDNFQHEENLLQQVASKDLLTNVQQLLVVTP
PILSSGMFIMVVRMFSLMCSNCPTLAVQLMKQNIAETLHFLLCGASNGSCQEQIDLVPRS
PQELYELTSLICELMPCLPKEGIFAVDTMLKKGNAQNTDGAIWQWRDDRGLWHPYNRIDS
RIIEQINEDTGTARAIQRKPNPLANSNTSGYSESKKDDARAQLMKEDPELAKSFIKTLFG
VLYEVYSSSAGPAVRHKCLRAILRIIYFADAELLKDVLKNHAVSSHIASMLSSQDLKIVV
GALQMAEILMQKLPDIFSVYFRREGVMHQVKHLAESESLLTSPPKACTNGSGSMGSTTSV
SSGTATAATHAAADLGSPSLQHSRDDSLDLSPQGRLSDVLKRKRLPKRGPRRPKYSPPRD
DDKVDNQAKSPTTTQSPKSSFLASLNPKTWGRLSTQSNSNNIEPARTAGGSGLARAASKD
TISNNREKIKGWIKEQAHKFVERYFSSENMDGSNPALNVLQRLCAATEQLNLQVDGGAEC
LVEIRSIVSESDVSSFEIQHSGFVKQLLLYLTSKSEKDAVSREIRLKRFLHVFFSSPLPG
EEPIGRVEPVGNAPLLALVHKMNNCLSQMEQFPVKVHDFPSGNGTGGSFSLNRGSQALKF
FNTHQLKCQLQRHPDCANVKQWKGGPVKIDPLALVQAIERYLVVRGYGRVREDDEDSDDD
GSDEEIDESLAAQFLNSGNVRHRLQFYIGEHLLPYNMTVYQAVRQFSIQAEDERESTDDE
SNPLGRAGIWTKTHTIWYKPVREDEESNKDCVGGKRGRAQTAPTKTSPRNAKKHDELWHD
GVCPSVSNPLEVYLIPTPPENITFEDPSLDVILLLRVLHAISRYWYYLYDNAMCKEIIPT
SEFINSKLTAKANRQLQDPLVIMTGNIPTWLTELGKTCPFFFPFDTRQMLFYVTAFDRDR
AMQRLLDTNPEINQSDSQDSRVAPRLDRKKRTVNREELLKQAESVMQDLGSSRAMLEIQY
ENEVGTGLGPTLEFYALVSQELQRADLGLWRGEEVTLSNPKGSQEGTKYIQNLQGLFALP
FGRTAKPAHIAKVKMKFRFLGKLMAKAIMDFRLVDLPLGLPFYKWMLRQETSLTSHDLFD
IDPVVARSVYHLEDIVRQKKRLEQDKSQTKESLQYALETLTMNGCSVEDLGLDFTLPGFP
NIELKKGGKDIPVTIHNLEEYLRLVIFWALNEGVSRQFDSFRDGFESVFPLSHLQYFYPE
ELDQLLCGSKADTWDAKTLMECCRPDHGYTHDSRAVKFLFEILSSFDNEQQRLFLQFVTG
SPRLPVGGFRSLNPPLTIVRKTFESTENPDDFLPSVMTCVNYLKLPDYSSIEIMREKLLI
AAREGQQSFHLS
NT seq
5979 nt
NT seq
+upstream
nt +downstream
nt
atgtccaaccggcctaataacaatccaggggggtcactgcgacgttcacagaggaacact
gccggggcccaaccacaagacgactcaataggaggaagaagctgcagttcatcatctgct
gtgatagttccacaaccagaggatccagacagagccaatacttcagaaagacaaaaaacg
gggcaggtgcctaagaaagacaattctcgaggagtgaagcgcagtgctagtccagactac
aacaggaccaattctcctagctctgcaaaaaaaccaaaagcacttcagcatactgaatct
ccctcagaaacaaataagccacatagtaagtcaaagaagagacatttagaccaggagcaa
caactgaaatctgcacaatcaccatcaacaagcaaggctcataccaggaagagtggggcc
actggcggttcacggagtcagaaaagaaaaaggacagagagttcttgtgtaaagagtggc
tccgggtctgaatcaactggtgcagaagagagatctgcgaaacctaccaagctggcttca
aaatcagccacctcagccaaagctgggtgtagcaccatcactgattcttcttctgctgcc
tctacttcctcctcgtcttctgctgtagcctcggcctcctccactgtaccaccaggtgcc
agagtgaaacaaggaaaagatcagaacaaggccaggcgttcccgttcagcgtccagtccc
agccccagaagaagtagcagggaaaaggaacagagtaaaactggtggctcttcaaaattt
gattgggctgctcgtttcagccctaaagttagccttcctaaaacaaaactgtctcttcca
gggtcttctaagtcagagacatcaaaacctggaccttctggattacaggccaaattagca
agtttaagaaaatctacgaagaaacgcagtgagtctccacctgctgagctccccagtttg
aggcggagcacacgccaaaagaccacgggctcctgtgctagtaccagtcggcgaggctct
ggcctgggcaaaagaggagcagctgaagctcgtcgacaggagaaaatggcagaccctgaa
agcaaccaggaggcagtaaattcttcagctgctcggacagatgaagctccccaaggagct
gcaggggctgttggcatgaccacctctggggagagtgaatcagatgattccgagatggga
cgtttgcaagctttgttagaggcaaggggtcttccccctcacctatttggtcctcttggt
cctcggatgtcacagcttttccatagaacaattggaagtggagctagttctaaggcccag
cagctactacaaggattgcaagccagtgatgaaagtcaacagcttcaggcagttattgag
atgtgtcagttactggtcatgggaaatgaggagacactgggagggtttcctgtcaagagt
gttgttccagctttgattacgttacttcagatggagcacaattttgatattatgaaccat
gcttgtcgagccttaacatacatgatggaagcacttcctcgatcttctgctgttgtagta
gatgctattcctgtctttttagaaaagctgcaagttattcagtgtattgatgtggcagag
caggccttgactgccttggagatgttgtcacggagacatagtaaagccattctacaggcg
ggtggtttggcagactgcttgctgtacctagaattcttcagcataaatgcccaaagaaat
gcattagcaattgcagctaattgctgccagagtatcacgccagatgaatttcattttgtg
gcagattcactcccattgctaacccaaaggctaacacatcaggataaaaagtcagtagaa
agcacttgcctttgttttgcacgcctagtggacaacttccagcatgaggagaatttactc
cagcaggttgcttccaaagatctgcttacaaatgttcaacagctgttggtagtgactcca
cccattttaagttctgggatgtttataatggtggttcgcatgttttctctgatgtgttcc
aactgtccaactttagctgttcaacttatgaaacaaaacattgcagaaacgcttcacttt
ctcctgtgtggtgcctccaatggaagttgtcaggaacagattgatcttgttccacgaagc
cctcaagagttgtatgaactgacatctctgatttgtgaacttatgccatgtttaccaaaa
gaaggcatttttgcagttgataccatgttgaagaagggaaatgcacagaacacagatggt
gcgatatggcagtggcgtgatgatcggggcctctggcatccatataacaggattgacagc
cggatcattgagcaaatcaatgaggacacgggaacagcacgtgccattcagagaaaacct
aacccgttagccaatagtaacactagtggatattcagagtcaaagaaggatgatgctcga
gcacagcttatgaaagaggatccggaactggctaagtcttttattaagacattatttggt
gttctttatgaagtgtatagttcctcagcaggacctgcggtcagacataagtgccttaga
gcaattcttaggataatttattttgcggatgctgaacttctgaaggatgttctgaaaaat
catgctgtttcaagtcacattgcttccatgctgtcaagccaagacctgaagatagtagtg
ggagcacttcagatggcagaaattttaatgcagaagttacctgatatttttagtgtttac
ttcagaagagaaggtgtaatgcatcaagtaaaacacttagcagaatcagagtctttgttg
acaagtccaccaaaggcatgtacgaatggatcgggatccatgggatccacaacttcagtc
agcagtgggacagccacagctgccactcatgctgcagctgacttgggatcacccagcttg
cagcacagcagggatgattctttagatctcagccctcaaggtcgattaagtgatgttcta
aagagaaaacgactgccaaaacgagggccaagaaggccaaagtactcacctccaagagat
gatgacaaagtagacaatcaagctaaaagccccaccactactcagtcacctaaatcttct
ttcctggcaagcttgaatccaaaaacatggggaaggttaagtacacagtccaacagcaac
aacattgagccagcacggactgcgggaggtagtggccttgccagggctgcctcaaaggat
accatctccaataatagagaaaaaattaaaggttggattaaggagcaggcacataaattt
gtagaacgttatttcagttctgagaatatggatggaagcaaccctgcattgaatgtcctt
cagagactttgtgctgcaaccgaacaactcaacctccaggtggatggtggagctgagtgc
cttgtagaaatccgtagcatagtctcagagtcagatgtttcatcatttgaaatccaacat
agtggatttgtgaagcagctgttgctttatttgacatctaaaagtgaaaaggatgctgtg
agcagagagatcagattaaagcgatttcttcatgtatttttttcttctccacttcctgga
gaagagcccattggaagagtggaaccagtgggtaatgcacctttgttggcattagttcac
aagatgaacaactgcctcagccagatggaacaatttccagtcaaagtacatgatttccct
agtggaaatgggacaggaggcagcttttctctcaacagaggatcacaggctttaaaattt
ttcaacacacatcaattaaaatgccagttacaaaggcatccagactgtgcaaatgtgaag
cagtggaagggtggacctgtcaagattgaccctctggctttggtacaagccatcgagaga
taccttgtagttagagggtatggaagagtaagagaagatgatgaagacagcgatgacgat
ggatcagatgaggaaatagatgagtctctggctgctcagttcctaaattcaggaaatgta
agacacaggctgcagttttatattggagaacatttgctgccgtataacatgactgtgtat
caggcagtacggcagtttagtatacaggctgaagatgaaagagaatccacagatgatgag
agcaatcctctaggcagagctggtatttggacaaagactcatacaatatggtataaacct
gtgagagaggatgaagaaagtaataaagattgtgttggtggtaaaagaggaagagcccaa
acagctccaacgaaaacttcccctagaaatgcaaaaaagcatgatgagttatggcacgat
ggagtgtgcccatcagtatcaaatcctttagaagtttacctcattcccacaccacctgaa
aatataacatttgaagacccgtcattagatgtgatccttcttttaagagttttacatgct
atcagtcgatactggtattacttgtatgataatgcaatgtgcaaggaaattattccaact
agtgaatttattaacagtaagttaacagcaaaagcaaataggcaacttcaagatccttta
gtaatcatgacaggaaacatcccaacatggcttactgagctaggaaaaacctgcccattt
ttctttccttttgatacccggcaaatgcttttttatgtaactgcatttgatcgggaccga
gcaatgcaaagattacttgataccaacccagaaatcaaccagtctgattctcaagatagc
agagttgcacctagattggatagaaaaaaacgtactgtgaaccgagaggagctgctgaaa
caggcggagtctgtgatgcaggacctcggcagctcacgggccatgttagaaatccagtat
gaaaatgaggttggtacaggtcttgggcctacactggagttttatgcgcttgtatctcag
gaactacagagagctgacttgggtctttggagaggtgaagaagtaactcttagcaatcca
aaagggagccaagaagggaccaagtatattcaaaacctccagggcctgtttgcgcttccc
tttggtaggacagcaaagccagctcatatcgcaaaggttaagatgaagtttcgcttctta
ggaaaattaatggccaaggctatcatggatttcagattggtggaccttccccttggctta
cccttttataaatggatgctacggcaagaaacttcactgacatcacacgatttgtttgac
atcgacccagttgtagccagatcagtttatcacctagaagacattgtcagacagaagaaa
agacttgaacaagataaatcccagaccaaagagagtctacagtatgcattagaaaccttg
actatgaatggctgctcagttgaagatctaggactggatttcactctgccagggtttccc
aatatcgaactgaagaaaggagggaaggatataccagtcactatccacaatttagaggag
tatctaagactggttatattctgggcactaaatgaaggcgtttctaggcaatttgattcg
ttcagagatggatttgaatcagtcttcccactcagtcatcttcagtacttctacccggag
gaactggatcagctcctttgtggcagtaaagcagacacttgggatgcaaagacactgatg
gaatgctgtaggcctgatcatggttatactcatgacagtcgggctgtgaagtttttgttt
gagattctcagtagttttgataatgagcagcagaggttatttctccagtttgtgactggt
agcccaagattgcctgttggaggattccggagtttgaatccacctttgacaattgtccga
aagacgtttgaatcaacagaaaacccagatgacttcttgccctctgtaatgacttgtgtg
aactatcttaagttgccggactattcaagcattgagataatgcgtgaaaaactgttgata
gcagcaagagaagggcagcagtcgttccatctttcctga
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integrated database retrieval system
