Homo sapiens (human): 9578
Help
Entry
9578 CDS
T01001
Symbol
CDC42BPB, CHOCNS, MRCKB
Name
(RefSeq) CDC42 binding protein kinase beta
KO
K16307
serine/threonine-protein kinase MRCK [EC:
2.7.11.1
]
Organism
hsa
Homo sapiens (human)
Disease
H02666
Chilton-Okur-Chung neurodevelopmental syndrome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
hsa01001
]
9578 (CDC42BPB)
Enzymes [BR:
hsa01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
9578 (CDC42BPB)
Protein kinases [BR:
hsa01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
9578 (CDC42BPB)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CNH
Pkinase
PH_MRCK
KELK
PK_Tyr_Ser-Thr
DMPK_coil
C1_1
Pkinase_C
DUF3450
PBD
PH
C1_2
Motif
Other DBs
NCBI-GeneID:
9578
NCBI-ProteinID:
NP_006026
OMIM:
614062
HGNC:
1738
Ensembl:
ENSG00000198752
UniProt:
Q9Y5S2
Q86XZ8
Structure
PDB
PDBj
LinkDB
All DBs
Position
14:complement(102932380..103057549)
Genome browser
AA seq
1711 aa
AA seq
DB search
MSAKVRLKKLEQLLLDGPWRNESALSVETLLDVLVCLYTECSHSALRRDKYVAEFLEWAK
PFTQLVKEMQLHREDFEIIKVIGRGAFGEVAVVKMKNTERIYAMKILNKWEMLKRAETAC
FREERDVLVNGDCQWITALHYAFQDENHLYLVMDYYVGGDLLTLLSKFEDKLPEDMARFY
IGEMVLAIDSIHQLHYVHRDIKPDNVLLDVNGHIRLADFGSCLKMNDDGTVQSSVAVGTP
DYISPEILQAMEDGMGKYGPECDWWSLGVCMYEMLYGETPFYAESLVETYGKIMNHEERF
QFPSHVTDVSEEAKDLIQRLICSRERRLGQNGIEDFKKHAFFEGLNWENIRNLEAPYIPD
VSSPSDTSNFDVDDDVLRNTEILPPGSHTGFSGLHLPFIGFTFTTESCFSDRGSLKSIMQ
SNTLTKDEDVQRDLEHSLQMEAYERRIRRLEQEKLELSRKLQESTQTVQSLHGSSRALSN
SNRDKEIKKLNEEIERLKNKIADSNRLERQLEDTVALRQEREDSTQRLRGLEKQHRVVRQ
EKEELHKQLVEASERLKSQAKELKDAHQQRKLALQEFSELNERMAELRAQKQKVSRQLRD
KEEEMEVATQKVDAMRQEMRRAEKLRKELEAQLDDAVAEASKERKLREHSENFCKQMESE
LEALKVKQGGRGAGATLEHQQEISKIKSELEKKVLFYEEELVRREASHVLEVKNVKKEVH
DSESHQLALQKEILMLKDKLEKSKRERHNEMEEAVGTIKDKYERERAMLFDENKKLTAEN
EKLCSFVDKLTAQNRQLEDELQDLAAKKESVAHWEAQIAEIIQWVSDEKDARGYLQALAS
KMTEELEALRSSSLGSRTLDPLWKVRRSQKLDMSARLELQSALEAEIRAKQLVQEELRKV
KDANLTLESKLKDSEAKNRELLEEMEILKKKMEEKFRADTGLKLPDFQDSIFEYFNTAPL
AHDLTFRTSSASEQETQAPKPEASPSMSVAASEQQEDMARPPQRPSAVPLPTTQALALAG
PKPKAHQFSIKSFSSPTQCSHCTSLMVGLIRQGYACEVCSFACHVSCKDGAPQVCPIPPE
QSKRPLGVDVQRGIGTAYKGHVKVPKPTGVKKGWQRAYAVVCDCKLFLYDLPEGKSTQPG
VIASQVLDLRDDEFSVSSVLASDVIHATRRDIPCIFRVTASLLGAPSKTSSLLILTENEN
EKRKWVGILEGLQSILHKNRLRNQVVHVPLEAYDSSLPLIKAILTAAIVDADRIAVGLEE
GLYVIEVTRDVIVRAADCKKVHQIELAPREKIVILLCGRNHHVHLYPWSSLDGAEGSFDI
KLPETKGCQLMATATLKRNSGTCLFVAVKRLILCYEIQRTKPFHRKFNEIVAPGSVQCLA
VLRDRLCVGYPSGFCLLSIQGDGQPLNLVNPNDPSLAFLSQQSFDALCAVELESEEYLLC
FSHMGLYVDPQGRRARAQELMWPAAPVACSCSPTHVTVYSEYGVDVFDVRTMEWVQTIGL
RRIRPLNSEGTLNLLNCEPPRLIYFKSKFSGAVLNVPDTSDNSKKQMLRTRSKRRFVFKV
PEEERLQQRREMLRDPELRSKMISNPTNFNHVAHMGPGDGMQVLMDLPLSAVPPSQEERP
GPAPTNLARQPPSRNKPYISWPSSGGSEPSVTVPLRSMSDPDQDFDKEPDSDSTKHSTPS
NSSNPSGPPSPNSPHRSQLPLEGLEQPACDT
NT seq
5136 nt
NT seq
+upstream
nt +downstream
nt
atgtcggccaaggtgcggctcaagaagctggagcagctgctcctggacgggccctggcgc
aacgagagcgccctgagcgtggaaacgctgctcgacgtgctcgtctgcctgtacaccgag
tgcagccactcggccctgcgccgcgacaagtacgtggccgagttcctcgagtgggctaaa
ccatttacacagctggtgaaagaaatgcagcttcatcgagaagactttgaaataattaaa
gtaattggaagaggtgcttttggtgaggttgctgttgtcaaaatgaagaatactgaacga
atttatgcaatgaaaatcctcaacaagtgggagatgctgaaaagagcagagaccgcgtgc
ttccgagaggagcgcgatgtgctggtgaacggcgactgccagtggatcaccgcgctgcac
tacgcctttcaggacgagaaccacctgtacttagtcatggattactatgtgggtggtgat
ttactgaccctgctcagcaaatttgaagacaagcttccggaagatatggcgaggttctac
attggtgaaatggtgctggccattgactccatccatcagcttcattacgtgcacagagac
attaaacctgacaatgtccttttggacgtgaatggtcatatccgcctggctgactttgga
tcatgtttgaagatgaatgatgatggcactgtgcagtcctccgtggccgtgggcacacct
gactacatctcgccggagatcctgcaggcgatggaggacggcatgggcaaatacgggcct
gagtgtgactggtggtctctgggtgtctgcatgtatgagatgctctatggagaaacgccg
ttttatgcggagtcactcgtggagacctatgggaagatcatgaaccatgaagagcgattc
cagttcccatcccatgtcacggatgtatctgaagaagcgaaggacctcatccagagactg
atctgcagtagagaacgccggctggggcagaatggaatagaggatttcaaaaagcatgcg
ttttttgaaggtctaaattgggaaaatatacgaaacctagaagcaccttatattcctgat
gtgagcagtccctctgacacatccaacttcgacgtggatgacgacgtgctgagaaacacg
gaaatattacctcctggttctcacacaggcttttctggattacatttgccattcattggt
tttacattcacaacggaaagctgtttttctgatcgaggctctctgaagagcataatgcag
tccaacacattaaccaaagatgaggatgtgcagcgggacctggagcacagcctgcagatg
gaagcttacgagaggaggattcggaggctggaacaggagaagctggagctgagcaggaag
ctgcaagagtccacccagaccgtgcagtccctccacggctcatctcgggccctcagcaat
tcaaaccgagataaagaaatcaaaaagctaaatgaagaaatcgaacgcttgaagaataaa
atagcagattcaaacaggctcgagcgacagcttgaggacacagtggcgcttcgccaagag
cgtgaggactccacgcagcggctgcgggggctggagaagcagcaccgcgtggtccggcag
gagaaggaggagctgcacaagcaactggttgaagcctcagagcggttgaaatcccaggcc
aaggaactcaaagatgcccatcagcagcgaaagctggccctgcaggagttctcggagctg
aacgagcgcatggcagagctccgtgcccagaagcagaaggtgtcccggcagctgcgagac
aaggaggaggagatggaggtggccacgcagaaggtggacgccatgcggcaggaaatgcgg
agagctgagaagctcaggaaagagctggaagctcagcttgatgatgctgttgctgaggcc
tccaaggagcgcaagcttcgtgagcacagcgagaacttctgcaagcaaatggaaagcgag
ctggaggccctcaaggtgaagcaaggaggccggggagcgggtgccaccttagagcaccag
caagagatttccaaaatcaaatccgagctggagaagaaagtcttattttatgaagaggaa
ttggtcagacgtgaggcctcccatgtgctagaagtgaaaaatgtgaagaaggaggtgcat
gattcagaaagccaccagctggccctgcagaaagaaatcttgatgttaaaagataagtta
gaaaagtcaaagcgagaacggcataacgagatggaggaggcagtaggtacaataaaagat
aaatacgaacgagaaagagcgatgctgtttgatgaaaacaagaagctaactgctgaaaat
gaaaagctctgttcctttgtggataaactcacagctcaaaatagacagctggaggatgag
ctgcaggatctggcagccaagaaggagtcagtggcccactgggaagctcagattgcggaa
atcattcagtgggtcagtgacgagaaagatgcccggggttaccttcaagctcttgcttcc
aagatgaccgaagagctcgaggctttgaggagttctagtctggggtcaagaacactggac
ccgctgtggaaggtgcgccgcagccagaagctggacatgtccgcgcggctggagctgcag
tcggccctggaggcggagatccgggccaagcagcttgtccaggaggagctcaggaaggtc
aaggacgccaacctcaccttggaaagcaaactaaaggattccgaagccaaaaacagagaa
ttattagaagaaatggaaattttgaagaaaaagatggaagaaaaattcagagcagatact
gggctcaaacttccagattttcaggattccatttttgagtatttcaacactgctcctctt
gcacatgacctgacatttagaaccagctcagctagtgagcaagaaacacaagctccgaag
ccagaagcgtccccgtcgatgtctgtggctgcatcagagcagcaggaggacatggctcgg
cccccgcagaggccatccgctgtgccgttgcccaccacgcaggccctggctctggctgga
ccgaagccaaaagctcaccagttcagcatcaagtccttctccagccctactcagtgcagc
cactgcacctccctgatggttgggctgatccggcagggctacgcctgcgaggtgtgttcc
tttgcttgccacgtgtcctgcaaagacggtgccccccaggtgtgcccaatacctcccgag
cagtccaagaggcctctgggcgtggacgtgcagcgaggcatcggaacagcctacaaaggc
catgtcaaggtcccaaagcccacgggggtgaagaagggatggcagcgcgcatatgcagtc
gtctgtgactgcaagctcttcctgtatgatctgcctgaaggaaaatccacccagcctggt
gtcattgcgagccaagtcttggatctcagagatgacgagttttccgtgagctcagtcctg
gcctcagatgtcattcatgctacacgccgagatattccatgtatattcagggtgacggcc
tctctcttaggtgcaccttctaagaccagctcgctgctcattctgacagaaaatgagaat
gaaaagaggaagtgggttgggattctagaaggactccagtccatccttcataaaaaccgg
ctgaggaatcaggtcgtgcatgttcccttggaagcctacgacagctcgctgcctctcatc
aaggccatcctgacagctgccatcgtggatgcagacaggattgcagtcggcctagaagaa
gggctctatgtcatagaggtcacccgagatgtgatcgtccgtgccgctgactgtaagaag
gtacaccagatcgagcttgctcccagggagaagatcgtaatcctcctctgtggccggaac
caccatgtgcacctctatccgtggtcgtcccttgatggagcggaaggcagctttgacatc
aagcttccggaaaccaaaggctgccagctcatggccacggccacactcaagaggaactct
ggcacctgcctgtttgtggccgtgaaacggctgatcctttgctatgagatccagagaacg
aagccattccacagaaagttcaatgagattgtggctcccggcagcgtgcagtgcctggcg
gtgctcagggacaggctctgtgtgggctacccttctgggttctgcctgctgagcatccag
ggggacgggcagcctctaaacctggtaaatcccaatgacccctcgcttgcgttcctctca
caacagtcttttgatgccctttgtgctgtggagctcgaaagcgaggagtacctgctttgc
ttcagccacatgggactgtacgtggacccgcaaggccggagggcacgcgcgcaggagctc
atgtggcctgcggctcctgtcgcctgtagttgcagccccacccacgtcacggtgtacagc
gagtatggcgtggacgtctttgatgtgcgcaccatggagtgggtgcagaccatcggcctg
cggaggataaggcccctgaactctgaaggcaccctcaacctcctcaactgcgagcctcca
cgcttgatctacttcaagagcaagttctcgggagcggttctcaacgtgccggacacctcc
gacaacagcaagaagcagatgctgcgcaccaggagcaaaaggcggttcgtcttcaaggtc
ccagaggaagagagactgcagcagaggcgagagatgcttagagacccagaattgagatcc
aaaatgatatccaacccaaccaacttcaaccacgtggcccacatgggcccaggcgacggc
atgcaggtgctcatggacctgcctctgagtgctgtgcccccctcccaggaggaaaggccg
ggccccgctcccaccaacctggctcgccagcctccatccaggaacaagccctacatctcg
tggccctcatcaggtggatcggagcctagcgtgactgtgcctctgagaagtatgtctgat
ccagaccaggactttgacaaagagcctgattcggactccaccaaacactcaactccatcg
aatagctccaaccccagcggcccaccgagccccaactccccccacaggagccagctcccc
ctcgaaggcctggagcagccggcctgtgacacctga
DBGET
integrated database retrieval system
