Homo sapiens (human): 9651
Help
Entry
9651 CDS
T01001
Symbol
PLCH2, PLC-L4, PLC-eta2, PLCL4, PLCeta2
Name
(RefSeq) phospholipase C eta 2
KO
K19006
phosphatidylinositol phospholipase C, eta [EC:
3.1.4.11
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa00562
Inositol phosphate metabolism
hsa01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
9651 (PLCH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
hsa04131
]
9651 (PLCH2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
9651 (PLCH2)
Membrane trafficking [BR:
hsa04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
9651 (PLCH2)
Endocytosis
Macropinocytosis
Phospholipase C
9651 (PLCH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
C2
EF-hand_like
EF-hand_7
PH_12
EF-hand_1
EF-hand_6
EF-hand_10
PH
EF-hand_8
EF-hand_5
AIF-1
EH
ABC_tran_Xtn
Motif
Other DBs
NCBI-GeneID:
9651
NCBI-ProteinID:
NP_055453
OMIM:
612836
HGNC:
29037
Ensembl:
ENSG00000149527
UniProt:
O75038
LinkDB
All DBs
Position
1:2415943..2505532
Genome browser
AA seq
1416 aa
AA seq
DB search
MSGPWPSPDSRTKGTVAWLAEVLLWVGGSVVLSSEWQLGPLVERCMGAMQEGMQMVKLRG
GSKGLVRFYYLDEHRSCIRWRPSRKNEKAKISIDSIQEVSEGRQSEVFQRYPDGSFDPNC
CFSIYHGSHRESLDLVSTSSEVARTWVTGLRYLMAGISDEDSLARRQRTRDQWLKQTFDE
ADKNGDGSLSIGEVLQLLHKLNVNLPRQRVKQMFREADTDDHQGTLGFEEFCAFYKMMST
RRDLYLLMLTYSNHKDHLDAASLQRFLQVEQKMAGVTLESCQDIIEQFEPCPENKSKGLL
GIDGFTNYTRSPAGDIFNPEHHHVHQDMTQPLSHYFITSSHNTYLVGDQLMSQSRVDMYA
WVLQAGCRCVEVDCWDGPDGEPIVHHGYTLTSKILFKDVIETINKYAFIKNEYPVILSIE
NHCSVIQQKKMAQYLTDILGDKLDLSSVSSEDATTLPSPQMLKGKILVKGKKLPANISED
AEEGEVSDEDSADEIDDDCKLLNGDASTNRKRVENTAKRKLDSLIKESKIRDCEDPNNFS
VSTLSPSGKLGRKSKAEEDVESGEDAGASRRNGRLVVGSFSRRKKKGSKLKKAASVEEGD
EGQDSPGGQSRGATRQKKTMKLSRALSDLVKYTKSVATHDIEMEAASSWQVSSFSETKAH
QILQQKPAQYLRFNQQQLSRIYPSSYRVDSSNYNPQPFWNAGCQMVALNYQSEGRMLQLN
RAKFSANGGCGYVLKPGCMCQGVFNPNSEDPLPGQLKKQLVLRIISGQQLPKPRDSMLGD
RGEIIDPFVEVEIIGLPVDCSREQTRVVDDNGFNPTWEETLVFMVHMPEIALVRFLVWDH
DPIGRDFIGQRTLAFSSMMPGYRHVYLEGMEEASIFVHVAVSDISGKVKQALGLKGLFLR
GPKPGSLDSHAAGRPPARPSVSQRILRRTASAPTKSQKPGRRGFPELVLGTRDTGSKGVA
DDVVPPGPGPAPEAPAQEGPGSGSPRDTRPLSTQRPLPPLCSLETIAEEPAPGPGPPPPA
AVPTSSSQGRPPYPTGPGANVASPLEDTEEPRDSRPRPCNGEGAGGAYERAPGSQTDGRS
QPRTLGHLPVIRRVKSEGQVPTEPLGGWRPLAAPFPAPAVYSDATGSDPLWQRLEPCGHR
DSVSSSSSMSSSDTVIDLSLPSLGLGRSRENLAGAHMGRLPPRPHSASAARPDLPPVTKS
KSNPNLRATGQRPPIPDELQPRSLAPRMAGLPFRPPWGCLSLVGVQDCPVAAKSKSLGDL
TADDFAPSFEGGSRRLSHSLGLPGGTRRVSGPGVRRDTLTEQLRWLTVFQQAGDITSPTS
LGPAGEGVAGGPGFVRRSSSRSHSRVRAIASRARQAQERQQRLQGLGRQGPPEEERGTPE
GACSVGHEGSVDAPAPSKGALGPASAAAENLVLLRL
NT seq
4251 nt
NT seq
+upstream
nt +downstream
nt
atgtctggtccatggccctcccccgacagccggaccaagggaacggtggcctggctggcg
gaggtactcctctgggttggagggagtgtggtgctgtcttcagagtggcagctcggcccc
ctggtggagcggtgcatgggtgccatgcaagaggggatgcagatggtgaagctgcgtggc
ggctccaagggcctggtccgcttctactacctggacgagcaccgctcctgcatccgctgg
aggccctcacgcaagaacgagaaggccaagatctccatcgactccatccaggaggtgagt
gaggggcggcagtcggaggtcttccagcgctaccctgacggcagcttcgaccccaactgc
tgcttcagcatctaccacggcagccaccgcgagtcgctggacctggtctccaccagcagc
gaggtggcgcgcacctgggtcactggcctgcgctacctcatggccggcatcagcgacgag
gacagcctggctcgccgccagcgcaccagggaccagtggctgaagcagacgtttgacgag
gccgacaagaacggggatggcagcctgagcattggcgaggtcctgcagctgctgcacaag
ctcaacgtgaacctgccccggcagagggtgaagcagatgttcagggaagcggacacggat
gaccaccaagggacgctgggttttgaagagttctgtgccttctacaagatgatgtccacc
cgccgggacctctacctgctcatgctgacctacagcaaccacaaggaccacctggatgcc
gccagcctgcagcgcttcctgcaggtggagcagaagatggcgggtgtgaccctcgagagc
tgccaggacatcatcgagcagtttgagccatgcccagaaaacaagagtaaggggctgctg
ggcattgatggcttcaccaactacaccaggagccctgctggtgacatcttcaaccctgag
caccaccatgtgcaccaggacatgacgcagccgctgagccactacttcatcacctcgtcc
cacaacacctacctcgtgggtgaccagctcatgtcccagtcacgggtggacatgtatgct
tgggtcctgcaggctggctgccgctgcgtggaggtggactgctgggatgggcccgacggg
gagcccattgtgcaccatggctacactctgacttccaagatcctcttcaaagacgtcatt
gaaaccatcaacaaatatgccttcatcaagaatgagtacccagtgatcctgtccatcgaa
aaccactgcagtgtcatccagcagaagaaaatggcccagtatctgactgacatccttggg
gacaagctggacctgtcatcagtgagcagtgaagatgccaccacactcccctctccacag
atgctcaagggcaagatcctcgtgaaggggaagaagctcccagccaacatcagcgaggat
gcggaggaaggcgaggtgtctgatgaggacagtgctgatgagattgacgatgactgcaag
ctcctcaatggggatgcatccaccaatcgaaagcgtgtagaaaacactgctaagaggaaa
ctggattccctcatcaaagagtcgaagattcgggactgtgaggaccccaacaacttctcc
gtctccacactgtccccatctggaaagctcggacgcaagagcaaggctgaagaggacgtg
gagtctggggaggatgccggggccagcagacgcaatggccgcctcgtcgtgggaagcttc
tccaggcgcaagaagaagggcagcaagctgaagaaggcggccagcgtggaggagggagat
gagggtcaggactccccgggaggccagagccgaggggcgacccggcagaagaagaccatg
aagctgtcccgggccctctctgacctggtgaagtacaccaagtccgtggccacccacgac
atagagatggaggcggcgtccagctggcaggtgtcgtccttcagcgagaccaaggcccac
cagattctgcagcagaagccggcgcagtacctacgcttcaaccagcagcagctctcccgc
atctacccctcctcctaccgtgtggactccagcaactacaacccgcagcccttctggaac
gccggctgccaaatggttgccctgaactaccagtcagaggggcggatgctgcagctgaac
cgagccaagttcagcgccaacggtggctgcggctacgtactcaagcctgggtgcatgtgc
cagggcgtgttcaaccccaactcggaggaccccctgcccgggcagctcaagaagcagctg
gtgctccggatcatcagtggccagcagcttcccaagccgcgcgactccatgctgggggac
cgtggggagatcatcgacccctttgtggaggtggagatcattgggctccctgtggactgc
agcagggagcagacccgcgtggtggacgacaacgggttcaaccccacctgggaggagacc
ctggttttcatggtgcacatgccggagatcgcgctggtccgcttcctcgtctgggaccac
gatcccatcgggcgtgacttcattggccagaggacgctggccttcagcagcatgatgcca
ggctacagacacgtgtacctagaagggatggaagaggcctccatcttcgtgcatgtggct
gtcagtgacatcagcggtaaggtcaagcaggctctgggcctaaaaggcctcttcctccga
ggcccaaagcccggctcgctggacagtcatgctgctgggcggcccccggcccggccctcc
gttagccagcggatcctgcggcgcacggccagcgccccgaccaagagccagaagccgggc
cgcaggggcttcccggagctggtcctgggtacacgggacacaggctccaagggggtggca
gacgatgtggtgccccccgggcccggacctgctccggaagccccagcccaggaggggccc
ggcagcggcagcccccgagacacccgccccctctccacgcagcggccactccccccactg
tgcagcctggaaaccatcgctgaggagcccgccccaggccctggtcccccgccaccagcg
gctgtccccaccagctcttctcagggacggcccccataccccacaggacccggagccaat
gtggcaagccccctagaggacactgaggagccccgagacagcaggcctcggccgtgcaac
ggcgagggcgccggcggggcatacgagagggcccccggcagccagacggacggcaggagc
cagccccggaccctgggccacctgcccgtgattagaagggtgaagagtgaggggcaggtg
cccacggagcccctgggagggtggcggcccctggccgctccctttccagctcctgccgtg
tactccgatgccacgggcagtgacccgctgtggcagcggctggagccatgtggccaccga
gacagcgtttcctcctcctccagcatgtcatccagcgacactgtcattgacctctccctg
cccagcctgggcctgggccgcagccgtgagaacctcgctggagcccacatgggacgcctg
ccccccaggccccactcggcttcggctgcccgcccagacctgccacctgtgaccaagagc
aaatccaaccccaaccttcgggctacaggccagcggcctcccatacctgacgaactgcag
cccaggtccctggccccaaggatggctggcctccccttccggcctccctggggctgcctt
tccctggtgggcgtgcaggactgccccgtggctgccaagtccaagagcctgggcgacctc
actgctgatgactttgcccctagctttgagggcggctcccgcagactgagccacagcctg
ggcctcccgggagggacacggcgggtgtcggggccaggggtgagacgggacaccctgaca
gagcagctgcgctggctcactgtcttccagcaggcaggagacatcacgtcacccaccagc
ctgggcccggctggggagggggtggcagggggccctggttttgtgcggcgctcctcctcc
cgcagccacagccgcgtgcgtgccattgccagccgggcccgccaggcccaggagcggcag
cagagactgcagggcctgggccggcagggacccccagaagaggagcggggcacccccgag
ggcgcctgctccgtgggccacgagggcagtgtggatgcaccagcaccctccaagggagcc
ctcgggccagcatccgcggctgctgaaaacctggtcctgctccgcctctga
DBGET
integrated database retrieval system
