KEGG   Homo sapiens (human): 9748
Entry
9748              CDS       T01001                                 
Symbol
SLK, LOSK, STK2, bA16H23.1, se20-9
Name
(RefSeq) STE20 like kinase
  KO
K08836  STE20-like kinase [EC:2.7.11.1]
Organism
hsa  Homo sapiens (human)
Pathway
hsa04114  Oocyte meiosis
Brite
KEGG Orthology (KO) [BR:hsa00001]
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    9748 (SLK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:hsa01001]
    9748 (SLK)
Enzymes [BR:hsa01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     9748 (SLK)
Protein kinases [BR:hsa01001]
 Serine/threonine kinases: STE group
  STE20 family
   9748 (SLK)
SSDB
Motif
Pfam: PKK Pkinase PK_Tyr_Ser-Thr
Other DBs
NCBI-GeneID: 9748
NCBI-ProteinID: NP_055535
OMIM: 616563
HGNC: 11088
Ensembl: ENSG00000065613
Pharos: Q9H2G2(Tchem)
UniProt: Q9H2G2
Structure
LinkDB
Position
10:103967140..104029233
AA seq 1235 aa
MSFFNFRKIFKLGSEKKKKQYEHVKRDLNPEDFWEIIGELGDGAFGKVYKAQNKETSVLA
AAKVIDTKSEEELEDYMVEIDILASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVM
LELERPLTESQIQVVCKQTLDALNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKN
TRTIQRRDSFIGTPYWMAPEVVMCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNP
MRVLLKIAKSEPPTLAQPSRWSSNFKDFLKKCLEKNVDARWTTSQLLQHPFVTVDSNKPI
RELIAEAKAEVTEEVEDGKEEDEEEETENSLPIPASKRASSDLSIASSEEDKLSQNACIL
ESVSEKTERSNSEDKLNSKILNEKPTTDEPEKAVEDINEHITDAQLEAMTELHDRTAVIK
ENEREKRPKLENLPDTEDQETVDINSVSEGKENNIMITLETNIEHNLKSEEEKDQEKQQM
FENKLIKSEEIKDTILQTVDLVSQETGEKEANIQAVDSEVGLTKEDTQEKLGEDDKTQKD
VISNTSDVIGTCEAADVAQKVDEDSAEDTQSNDGKEVVEVGQKLINKPMVGPEAGGTKEV
PIKEIVEMNEIEEGKNKEQAINSSENIMDINEEPGTTEGEEITESSSTEEMEVRSVVADT
DQKALGSEVQDASKVTTQIDKEKKEIPVSIKKEPEVTVVSQPTEPQPVLIPSININSDSG
ENKEEIGSLSKTETILPPESENPKENDNDSGTGSTADTSSIDLNLSISSFLSKTKDSGSI
SLQETRRQKKTLKKTRKFIVDGVEVSVTTSKIVTDSDSKTEELRFLRRQELRELRFLQKE
EQRAQQQLNSKLQQQREQIFRRFEQEMMSKKRQYDQEIENLEKQQKQTIERLEQEHTNRL
RDEAKRIKGEQEKELSKFQNMLKNRKKEVINEVEKAPKELRKELMKRRKEELAQSQHAQE
QEFVQKQQQELDGSLKKIIQQQKAELANIERECLNNKQQLMRAREAAIWELEERHLQEKH
QLLKQQLKDQYFMQRHQLLKRHEKETEQMQRYNQRLIEELKNRQTQERARLPKIQRSEAK
TRMAMFKKSLRINSTATPDQDRDKIKQFAAQEEKRQKNERMAQHQKHENQMRDLQLQCEA
NVRELHQLQNEKCHLLVEHETQKLKELDEEHSQELKEWREKLRPRKKTLEEEFARKLQEQ
EVFFKMTGESECLNPSTQSRISKFYPIPSLHSTGS
NT seq 3708 nt   +upstreamnt  +downstreamnt
atgtccttcttcaatttccgtaagatcttcaagttggggagcgagaagaagaagaagcag
tacgaacacgtgaagagggacctgaaccccgaagacttttgggagattataggagaactg
ggcgacggagcctttgggaaagtgtacaaggcccagaataaagagaccagtgttttagct
gctgcaaaagtgattgacactaaatctgaagaagaacttgaagattacatggtagagatt
gacatattagcatcttgtgatcacccaaatatagtcaagcttctagatgccttctattat
gagaacaatctttggatcctcattgaattttgtgcaggtggagcagtagatgctgtgatg
cttgaacttgagagaccattaactgagtcccaaatacaagtagtttgcaagcagacttta
gatgcattgaactacttacatgataataagatcatccacagagatctgaaggctggcaac
attctctttaccttagatggagatatcaaattggcggattttggagtatcagctaaaaac
acgaggacaattcaaagaagagattcctttattggtacaccatattggatggctcctgaa
gtagtcatgtgtgaaacatctaaggacagaccctatgactacaaagctgatgtttggtcc
ctgggtatcactttaatagaaatggctgagatagaaccacctcatcatgaattaaatcca
atgcgagtgctgctaaaaatagcaaaatctgagccacctacattagcacagccatccaga
tggtcttcaaattttaaggactttctaaagaaatgcttagaaaagaatgtggatgccagg
tggactacatctcagctgctgcagcatccctttgttactgttgattccaacaaacccatc
cgagaattgattgcagaggcgaaggctgaagtaacagaagaagttgaagatggcaaagag
gaagatgaagaggaggaaacagaaaattctctgccaatacctgcaagtaagcgtgcatct
tctgaccttagtatcgccagctctgaagaagataaactttcacaaaatgcttgtattttg
gagtctgtctcagaaaaaacagaacgtagtaactctgaagataaactcaacagcaaaatt
cttaatgaaaaacccaccactgatgaacctgaaaaggctgtggaggatattaatgaacat
attaccgatgctcagttagaagcaatgactgaactccatgacagaacagcagtaatcaag
gagaatgaaagagagaagaggcccaagcttgaaaatctgcctgacacagaagaccaagaa
actgtggacattaattcagtcagtgaaggaaaagagaataatataatgataaccttagaa
acaaatattgaacataatctaaaatctgaggaagaaaaggatcaggaaaagcaacagatg
tttgaaaataagcttataaaatctgaagaaattaaagatactattttgcaaacagtagat
ttagtttctcaagagactggagaaaaagaggcaaatattcaggcagttgatagtgaagtt
gggcttacaaaggaagacacccaagagaaattgggggaagacgacaaaactcaaaaagat
gtgatcagcaatacaagtgatgtgataggaacatgtgaggcagcagatgtggctcagaaa
gtggatgaagacagtgctgaggatacgcagagtaatgatgggaaagaagtggtcgaagta
ggccagaaattaattaataagcccatggtgggtcctgaggctggtggtactaaggaagtt
cctattaaagaaatagttgaaatgaatgaaatagaagaaggtaaaaataaggaacaagca
ataaacagttcagagaacataatggacatcaatgaggaaccaggaacaactgaaggtgaa
gaaatcactgagtcaagtagcactgaagaaatggaggtcagaagtgtggtggctgatact
gaccaaaaggctttaggaagtgaagttcaggatgcttctaaagtcactactcagatagat
aaagagaaaaaagaaattccagtgtcaattaaaaaagagcctgaagttactgtagtttca
cagcccactgaacctcagcctgttctaatacccagtattaatatcaactctgacagtgga
gaaaataaagaagaaataggttctttatcaaaaactgaaactattctgccaccagaatct
gagaatccaaaggaaaatgataatgattcaggcactggttccactgctgatactagcagt
attgacttgaatttatccatctctagctttctaagtaaaactaaagacagtggatcgata
tctttacaagaaacaagaagacaaaagaaaacattgaagaaaacacgcaaatttattgtt
gatggtgtagaagtgagtgtaacaacatcaaagatagttacagatagtgattccaaaact
gaagaattgcggtttcttagacgtcaggaacttcgggaattaagatttcttcagaaagaa
gagcaaagagcccaacaacagctcaatagcaaactacagcaacaacgagaacaaattttc
cggcgctttgagcaggaaatgatgagtaaaaagcgacaatatgaccaggaaattgagaat
ctagaaaaacagcagaaacagactatcgaacgcctggaacaagagcacacaaatcgcttg
cgagatgaagccaaacgcatcaaaggagaacaagagaaagagttgtccaaatttcagaat
atgctgaagaaccgaaagaaggaggttataaatgaagtggagaaagcacccaaagagctg
agaaaagagctcatgaaacgcaggaaagaggagcttgcacaaagccagcatgctcaggaa
caagagtttgttcagaaacaacagcaagaattagatggctctctgaaaaagatcatccag
cagcagaaggcagagttagctaatattgagagagagtgcctgaataacaagcaacagctc
atgagagctcgagaagctgcaatttgggagctcgaagaacgacacttacaagaaaaacac
cagctgctcaaacagcagcttaaagatcagtatttcatgcaaagacatcagctacttaag
cgccacgagaaggaaacagagcaaatgcagcgttacaatcaaagacttattgaggaattg
aaaaacagacagactcaagaaagagcaagactgcccaagattcagcgcagtgaagccaag
actcgaatggccatgtttaagaagagtttgagaattaactcaacagccacaccagatcag
gaccgtgataaaattaaacagtttgctgcacaagaagaaaagaggcagaaaaatgagaga
atggctcagcatcagaaacatgagaatcaaatgcgagatcttcagttgcagtgtgaagcc
aatgtccgcgaactgcatcagctgcagaatgaaaaatgccacttgttggttgagcatgag
actcagaaactgaaggagttagatgaggaacatagccaagaattaaaggagtggagagag
aaattgagacctaggaaaaagacactggaagaagagtttgccaggaaactacaggaacag
gaagtattctttaaaatgactggggagtctgaatgccttaacccatcaacacagagccgg
atttccaaattttatcctattcccagcttgcattccaccggatcataa

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