Homo sapiens (human): 9775
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Entry
9775 CDS
T01001
Symbol
EIF4A3, DDX48, Fal1, MUK34, NMP265, NUK34, RCPS, eIF-4A-III, eIF4A-III, eIF4AIII
Name
(RefSeq) eukaryotic translation initiation factor 4A3
KO
K13025
ATP-dependent RNA helicase [EC:
5.6.2.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03013
Nucleocytoplasmic transport
hsa03015
mRNA surveillance pathway
hsa03040
Spliceosome
Disease
H02503
Richieri-Costa-Pereira syndrome
Drug target
Zotatifin:
D11837
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
9775 (EIF4A3)
09122 Translation
03013 Nucleocytoplasmic transport
9775 (EIF4A3)
03015 mRNA surveillance pathway
9775 (EIF4A3)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
9775 (EIF4A3)
03041 Spliceosome [BR:
hsa03041
]
9775 (EIF4A3)
03009 Ribosome biogenesis [BR:
hsa03009
]
9775 (EIF4A3)
03012 Translation factors [BR:
hsa03012
]
9775 (EIF4A3)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.7 DEAD-box RNA helicase
9775 (EIF4A3)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
Transport factors
EJC complex
9775 (EIF4A3)
mRNA cycle factors
Stress granule specific factors
9775 (EIF4A3)
Spliceosome [BR:
hsa03041
]
Complex C
Other components
EJC/TREX
9775 (EIF4A3)
Ribosome biogenesis [BR:
hsa03009
]
Eukaryotic type
90S particles
Helicases
9775 (EIF4A3)
Translation factors [BR:
hsa03012
]
Eukaryotic type
Initiation factors
eIF-4
9775 (EIF4A3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DEAD
Helicase_C
ResIII
AAA_19
Cas3-like_C_2
AAA_30
AAA_22
Flavi_DEAD
Motif
Other DBs
NCBI-GeneID:
9775
NCBI-ProteinID:
NP_055555
OMIM:
608546
HGNC:
18683
Ensembl:
ENSG00000141543
UniProt:
P38919
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(80134369..80147128)
Genome browser
AA seq
411 aa
AA seq
DB search
MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK
PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV
QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA
IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL
VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA
NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL
YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
NT seq
1236 nt
NT seq
+upstream
nt +downstream
nt
atggcgaccacggccacgatggcgacctcgggctcggcgcgaaagcggctgctcaaagag
gaagacatgactaaagtggaattcgagaccagcgaggaggtggatgtgacccccacgttc
gacaccatgggcctgcgggaggacctgctgcggggcatctacgcttacggttttgaaaaa
ccatcagcaatccagcaacgagcaatcaagcagatcatcaaagggagagatgtcatcgca
cagtctcagtccggcacaggaaaaacagccaccttcagtatctcagtcctccagtgtttg
gatattcaggttcgtgaaactcaagctttgatcttggctcccacaagagagttggctgtg
cagatccagaaggggctgcttgctctcggtgactacatgaatgtccagtgccatgcctgc
attggaggcaccaatgttggcgaggacatcaggaagctggattacggacagcatgttgtc
gcgggcactccagggcgtgtttttgatatgattcgtcgcagaagcctaaggacacgtgct
atcaaaatgttggttttggatgaagctgatgaaatgttgaataaaggtttcaaagagcag
atttacgatgtatacaggtacctgcctccagccacacaggtggttctcatcagtgccacg
ctgccacacgagattctggagatgaccaacaagttcatgaccgacccaatccgcatcttg
gtgaaacgtgatgaattgactctggaaggcatcaagcaatttttcgtggcagtggagagg
gaagagtggaaatttgacactctgtgtgacctctacgacacactgaccatcactcaggcg
gtcatcttctgcaacaccaaaagaaaggtggactggctgacggagaaaatgagggaagcc
aacttcactgtatcctcaatgcatggagacatgccccagaaagagcgggagtccatcatg
aaggagttccggtcgggcgccagccgagtgcttatttctacagatgtctgggccaggggg
ttggatgtccctcaggtgtccctcatcattaactatgatctccctaataacagagaattg
tacatacacagaattgggagatcaggtcgatacggccggaagggtgtggccattaacttt
gtaaagaatgacgacatccgcatcctcagagatatcgagcagtactattccactcagatt
gatgagatgccgatgaacgttgctgatcttatctga
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integrated database retrieval system
