| Entry |
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| Symbol |
PIEZO1, DHS, ER, FAM38A, LMPH3, LMPHM6, Mib
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| Name |
(RefSeq) piezo type mechanosensitive ion channel component 1 (Er blood group)
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| KO |
| K22128 | piezo-type mechanosensitive ion channel component 1/2 |
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| Organism |
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| Disease |
| H00232 | Hereditary stomatocytosis |
| H01978 | Dehydrated hereditary stomatocytosis |
| H02001 | Familial pseudohyperkalemia |
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| Brite |
KEGG Orthology (KO) [BR:hsa00001]
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:hsa04131]
9780 (PIEZO1)
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:hsa04040]
9780 (PIEZO1)
Membrane trafficking [BR:hsa04131]
Endoplasmic reticulum (ER) - Golgi transport
Others
Others
9780 (PIEZO1)
Ion channels [BR:hsa04040]
Other channels
Mechanosensitive channel (Piezo)
9780 (PIEZO1)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
16:complement(88715338..88785220)
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| AA seq |
2521 aa
MEPHVLGAVLYWLLLPCALLAACLLRFSGLSLVYLLFLLLLPWFPGPTRCGLQGHTGRLL
RALLGLSLLFLVAHLALQICLHIVPRLDQLLGPSCSRWETLSRHIGVTRLDLKDIPNAIR
LVAPDLGILVVSSVCLGICGRLARNTRQSPHPRELDDDERDVDASPTAGLQEAATLAPTR
RSRLAARFRVTAHWLLVAAGRVLAVTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPI
STRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGPTNCSSPH
ALVLNTGLDWPVYASPGVLLLLCYATASLRKLRAYRPSGQRKEAAKGYEARELELAELDQ
WPQERESDQHVVPTAPDTEADNCIVHELTGQSSVLRRPVRPKRAEPREASPLHSLGHLIM
DQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCL
RYVWAMDLRPELPTTLGPVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLK
WAESPAALTEVTVADTEPTRTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGRLVVY
KIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLT
GFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTR
LPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQATQVPEGAAK
WGLVAERLLELAAGFSDVLSRVQVFLRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVL
WAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTE
ISQSLLYRGPVDPANWFGVRKGFPNLGYIQNHLQVLLLLVFEAIVYRRQEHYRRQHQLAP
LPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGC
WLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSA
LIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRG
EPNPVPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFG
TALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFSLVCTV
KGYYDPKEMMDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALL
ASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDRSRPQDTLGP
KDPGLEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEAVPEDPRPSA
QSAFQLAYQAWVTNAQAVLRRRQQEQEQARQEQAGQLPTGGGPSQEVEPAEGPEEAAAGR
SHVVQRVLSTAQFLWMLGQALVDELTRWLQEFTRHHGTMSDVLRAERYLLTQELLQGGEV
HRGVLDQLYTSQAEATLPGPTEAPNAPSTVSSGLGAEEPLSSMTDDMGSPLSTGYHTRSG
SEEAVTDPGEREAGASLYQGLMRTASELLLDRRLRIPELEEAELFAEGQGRALRLLRAVY
QCVAAHSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIA
VVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQL
LCYGLWDHEEDSPSKEHDKSGEEEQGAEEGPGVPAATTEDHIQVEARVGPTDGTPEPQVE
LRPRDTRRISLRFRRRKKEGPARKGAAAIEAEDREEEEGEEEKEAPTGREKRPSRSGGRV
RAAGRRLQGFCLSLAQGTYRPLRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFW
AFGKHSAATDITSSLSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLA
IHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNH
LNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYP
QPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYE
PLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRI
SPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLAS
LLEGTSDQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGF
LEWWVIELQECRTDCNLLPMVIFSDKVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFS
EISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREK
E |
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| NT seq |
7566 nt +upstreamnt +downstreamnt
atggagccgcacgtgctcggcgcggtcctgtactggctgctgctgccctgcgcgctgctg
gctgcctgcctgctccgcttcagcggactctcgctggtctacctgctcttcctgctgctg
ctgccctggttccccggccccacccgatgcggcctccaaggtcacacaggccgcctcctg
cgggcattgctgggcctcagcctgctcttcctggtggcccatctcgccctccagatctgc
ctgcatattgtgccccgcctggaccagctcctgggacccagctgcagccgctgggagacc
ctctcgcgacacataggggtcacaaggctggacctgaaggacatccccaacgccatccgg
ctggtggcccctgacctgggcatcttggtggtctcctctgtctgcctcggcatctgcggg
cgccttgcaaggaacacccggcagagcccacatccacgggagctggatgatgatgagagg
gatgtggatgccagcccgacggcagggctgcaggaagcagcaacgctggcccctacacgg
aggtcacggctggccgctcgtttccgagtcacggcccactggctgctggtggcggctggg
cgggtcctggccgtaacactgcttgcactggcaggcatcgcccacccctcggccctctcc
agtgtctacctgctgctcttcctggccctctgcacctggtgggcctgccactttcccatc
agcactcggggcttcagcagactctgcgtcgcggtggggtgcttcggcgccggccatctc
atctgcctctactgctaccagatgcccttggcacaggctctgctcccgcctgccggcatc
tgggctagggtgctgggtctcaaggacttcgtgggtcccaccaactgctccagcccccac
gcgctggtcctcaacaccggcctggactggcctgtgtatgccagccccggcgtcctcctg
ctgctgtgctacgccacggcctctctgcgcaagctccgcgcgtaccgcccctccggccag
aggaaggaggcggcaaaggggtatgaggctcgggagctggagctagcagagctggaccag
tggccccaggaacgggagtctgaccagcacgtggtgcccacagcacccgacaccgaggct
gataactgcatcgtgcacgagctgaccggccagagctccgtcctgcggcggcctgtgcgg
cccaagcgggctgagcccagggaggcgtctccgctccacagcctgggccacctcatcatg
gaccagagctatgtgtgcgcgctcattgccatgatggtatggagcatcacctaccacagc
tggctgaccttcgtactgctgctctgggcctgcctcatctggacggtgcgcagccgccac
caactggccatgctgtgctcgccctgcatcctgctgtatgggatgacgctgtgctgccta
cgctacgtgtgggccatggacctgcgccctgagctgcccaccaccctgggccccgtcagc
ctgcgccagctggggctggagcacacccgctacccctgtctggaccttggtgccatgttg
ctctacaccctgaccttctggctcctgctgcgccagtttgtgaaagagaagctgctgaag
tgggcagagtctccagctgcgctgacggaggtcaccgtggcagacacagagcccacgcgg
acgcagacgctgttgcagagcctgggggagctggtgaagggcgtgtacgccaagtactgg
atctatgtgtgtgctggcatgttcatcgtggtcagcttcgccggccgcctcgtggtctac
aagattgtctacatgttcctcttcctgctctgcctcaccctcttccaggtctactacagc
ctgtggcggaagctgctcaaggccttctggtggctcgtggtggcctacaccatgctggtc
ctcatcgccgtctacaccttccagttccaggacttccctgcctactggcgcaacctcact
ggcttcaccgacgagcagctgggggacctgggcctggagcagttcagcgtgtccgagctc
ttctccagcatcctggtgcccggcttcttcctcctggcctgcatcctgcagctgcactac
ttccacaggcccttcatgcagctcaccgacatggagcacgtgtccctgcctggcacgcgc
ctcccgcgctgggctcacaggcaggatgcagtgagtgggaccccactgctgcgggaggag
cagcaggagcatcagcagcagcagcaggaggaggaggaggaggaggaggactccagggac
gaggggctgggcgtggccactccccaccaggccacgcaggtgcctgaaggggcagccaag
tggggcctggtggctgagcggctgctggagctggcagccggcttctcggacgtcctctca
cgcgtgcaggtgttcctgcggcggctgctggagcttcacgttttcaagctggtggccctg
tacaccgtctgggtggccctgaaggaggtgtcggtgatgaacctgctgctggtggtgctg
tgggccttcgccctgccctacccacgcttccggcccatggcctcctgcctgtccaccgtg
tggacctgcgtcatcatcgtgtgtaagatgctgtaccagctcaaggttgtcaacccccag
gagtattccagcaactgcaccgagcccttccccaacagcaccaacttgctgcccacggag
atcagccagtccctgctgtaccgggggcccgtggaccctgccaactggtttggggtgcgg
aaagggttccccaacctgggctacatccagaaccacctgcaagtgctgctgctgctggta
ttcgaggccatcgtgtaccggcgccaggagcactaccgccggcagcaccagctggccccg
ctgcctgcccaggccgtgtttgccagcggcacccgccagcagctggaccaggatctgctc
ggctgcctcaagtacttcatcaacttcttcttctacaaattcgggctggagatctgcttc
ctgatggccgtgaacgtgatcgggcagcgcatgaactttctggtgaccctgcacggttgc
tggctggtggccatcctcacccgcaggcaccgccaggccattgcccgcctctggcccaac
tactgcctcttcctggcgctgttcctgctgtaccagtacctgctgtgcctggggatgccc
ccggccctgtgcattgattatccctggcgctggagccgggccgtccccatgaactccgca
ctcatcaagtggctgtacctgcctgatttcttccgggcccccaactccaccaacctcatc
agcgactttctcctgctgctgtgcgcctcccagcagtggcaggtgttctcagctgagcgc
acagaggagtggcagcgcatggctggcgtcaacaccgaccgcctggagccgctgcggggg
gagcccaaccccgtgcccaactttatccactgcaggtcctaccttgacatgctgaaggtg
gccgtcttccgatacctgttctggctggtgctggtggtggtgtttgtcacgggggccacc
cgcatcagcatcttcgggctgggctacctgctggcctgcttctacctgctgctcttcggc
acggccctgctgcagagggacacacgggcccgcctcgtgctgtgggactgcctcattctg
tacaacgtcaccgtcatcatctccaagaacatgctgtcgctcctggcctgcgtcttcgtg
gagcagatgcagaccggcttctgctgggtcatccagctcttcagccttgtatgcaccgtc
aagggctactatgaccccaaggagatgatggacagagaccaggactgcctgctgcctgtg
gaggaggctggcatcatctgggacagcgtctgcttcttcttcctgctgctgcagcgccgc
gtcttccttagccattactacctgcacgtcagggccgacctccaggccaccgccctgcta
gcctccaggggcttcgccctctacaacgctgccaacctcaagagcattgactttcaccgc
aggatagaggagaagtccctggcccagctgaaaagacagatggagcgtatccgtgccaag
caggagaagcacaggcagggccgggtggaccgcagtcgcccccaggacaccctgggcccc
aaggaccccggcctggagccagggcccgacagtccagggggctcctccccgccacggagg
cagtggtggcggccctggctggaccacgccacagtcatccactccggggactacttcctg
tttgagtccgacagtgaggaagaggaggaggctgttcctgaagacccgaggccgtcggca
cagagtgccttccagctggcgtaccaggcatgggtgaccaacgcccaggcggtgctgagg
cggcggcagcaggagcaggagcaggcaaggcaggaacaggcaggacagctacccacagga
ggtggtcccagccaggaggtggagccagcagagggccccgaggaggcagcggcaggccgg
agccatgtggtgcagagggtgctgagcacggcgcagttcctgtggatgctggggcaggcg
ctagtggatgagctgacacgctggctgcaggagttcacccggcaccacggcaccatgagc
gacgtgctgcgggcagagcgctacctcctcacacaggagctcctgcagggcggcgaagtg
cacaggggcgtgctggatcagctgtacacaagccaggccgaggccacgctgccaggcccc
accgaggcccccaatgccccaagcaccgtgtccagtgggctgggcgcggaggagccactc
agcagcatgacagacgacatgggcagccccctgagcaccggctaccacacgcgcagtggc
agtgaggaggcagtcaccgaccccggggagcgtgaggctggtgcctctctgtaccaggga
ctgatgcggacggccagcgagctgctcctggacaggcgcctgcgcatcccagagctggag
gaggcagagctgtttgcggaggggcagggccgggcgctgcggctgctgcgggccgtgtac
cagtgtgtggccgcccactcggagctgctctgctacttcatcatcatcctcaaccacatg
gtcacggcctccgccggctcgctggtgctgcccgtgctcgtcttcctgtgggccatgctg
tcgatcccgaggcccagcaagcgcttctggatgacggccatcgtcttcaccgagatcgcg
gtggtcgtcaagtacctgttccagtttgggttcttcccctggaacagccacgtggtgctg
cggcgctacgagaacaagccctacttcccgccccgcatcctgggcctggagaagactgac
ggctacatcaagtacgacctggtgcagctcatggcccttttcttccaccgctcccagctg
ctgtgctatggcctctgggaccatgaggaggactcaccatccaaggagcatgacaagagc
ggcgaggaggagcagggagccgaggaggggccaggggtgcctgcggccaccaccgaagac
cacattcaggtggaagccagggtcggacccacggacgggaccccagaaccccaagtggag
ctcaggccccgtgatacgaggcgcatcagtctacgttttagaagaaggaagaaggagggc
ccagcacggaaaggagcggcagccatcgaagctgaggacagggaggaagaagagggggag
gaagagaaagaggcccccacggggagagagaagaggccaagccgctctggaggaagagta
agggcggccgggcggcggctgcagggcttctgcctgtccctggcccagggcacatatcgg
ccgctacggcgcttcttccacgacatcctgcacaccaagtaccgcgcagccaccgacgtc
tatgccctcatgttcctggctgatgttgtcgacttcatcatcatcatttttggcttctgg
gcctttgggaagcactcggcggccacagacatcacgtcctccctatcagacgaccaggta
cccgaggctttcctggtcatgctgctgatccagttcagtaccatggtggttgaccgcgcc
ctctacctgcgcaagaccgtgctgggcaagctggccttccaggtggcgctggtgctggcc
atccacctatggatgttcttcatcctgcccgccgtcactgagaggatgttcaaccagaat
gtggtggcccagctctggtacttcgtgaagtgcatctacttcgccctgtccgcctaccag
atccgctgcggctaccccacccgcatcctcggcaacttcctcaccaagaagtacaatcat
ctcaacctcttcctcttccaggggttccggctggtgccgttcctggtggagctgcgggca
gtgatggactgggtgtggacggacaccacgctgtccctgtccagctggatgtgtgtggag
gacatctatgccaacatcttcatcatcaaatgcagccgagagacagagaagaaatacccg
cagcccaaagggcagaagaagaagaagatcgtcaagtacggcatgggtggcctcatcatc
ctcttcctcatcgccatcatctggttcccactgctcttcatgtcgctggtgcgctccgtg
gttggggttgtcaaccagcccatcgatgtcaccgtcaccctgaagctgggcggctatgag
ccgctgttcaccatgagcgcccagcagccgtccatcatccccttcacggcccaggcctat
gaggagctgtcccggcagtttgacccccagccgctggccatgcagttcatcagccagtac
agccctgaggacatcgtcacggcgcagattgagggcagctccggggcgctgtggcgcatc
agtccccccagccgtgcccagatgaagcgggagctctacaacggcacggccgacatcacc
ctgcgcttcacctggaacttccagagggacctggcgaagggaggcactgtggagtatgcc
aacgagaagcacatgctggccctggcccccaacagcactgcacggcggcagctggccagc
ctgctcgagggcacctcggaccagtctgtggtcatccctaatctcttccccaagtacatc
cgtgcccccaacgggcccgaagccaaccctgtgaagcagctgcagcccaatgaggaggcc
gactacctcggcgtgcgtatccagctgcggagggagcagggtgcgggggccaccggcttc
ctcgaatggtgggtcatcgagctgcaggagtgccggaccgactgcaacctgctgcccatg
gtcattttcagtgacaaggtcagcccaccgagcctcggcttcctggctggctacggcatc
atggggctgtacgtgtccatcgtgctggtcatcggcaagttcgtgcgcggattcttcagc
gagatctcgcactccattatgttcgaggagctgccgtgcgtggaccgcatcctcaagctc
tgccaggacatcttcctggtgcgggagactcgggagctggagctggaggaggagttgtac
gccaagctcatcttcctctaccgctcaccggagaccatgatcaagtggactcgtgagaag
gagtag |
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