Homo sapiens (human): 9846
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Entry
9846 CDS
T01001
Symbol
GAB2
Name
(RefSeq) GRB2 associated binding protein 2
KO
K08091
GRB2-associated-binding protein 2
Organism
hsa
Homo sapiens (human)
Pathway
hsa04014
Ras signaling pathway
hsa04071
Sphingolipid signaling pathway
hsa04072
Phospholipase D signaling pathway
hsa04380
Osteoclast differentiation
hsa04664
Fc epsilon RI signaling pathway
hsa04666
Fc gamma R-mediated phagocytosis
hsa05220
Chronic myeloid leukemia
Network
nt06526
MAPK signaling
Element
N01595
Regulation of GF-RTK-RAS-ERK signaling pathway, adaptor proteins
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
9846 (GAB2)
04072 Phospholipase D signaling pathway
9846 (GAB2)
04071 Sphingolipid signaling pathway
9846 (GAB2)
09150 Organismal Systems
09151 Immune system
04664 Fc epsilon RI signaling pathway
9846 (GAB2)
04666 Fc gamma R-mediated phagocytosis
9846 (GAB2)
09158 Development and regeneration
04380 Osteoclast differentiation
9846 (GAB2)
09160 Human Diseases
09162 Cancer: specific types
05220 Chronic myeloid leukemia
9846 (GAB2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04990 Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
9846 (GAB2)
Domain-containing proteins not elsewhere classified [BR:
hsa04990
]
Pleckstrin homology (PH) domain-containing proteins
Grb-2 associated binder (Gab) family proteins
9846 (GAB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PH
PH_11
PH_9
PH_2
PH_3
PH_8
Motif
Other DBs
NCBI-GeneID:
9846
NCBI-ProteinID:
NP_536739
OMIM:
606203
HGNC:
14458
Ensembl:
ENSG00000033327
UniProt:
Q9UQC2
Structure
PDB
LinkDB
All DBs
Position
11:complement(78215293..78417820)
Genome browser
AA seq
676 aa
AA seq
DB search
MSGGGDVVCTGWLRKSPPEKKLRRYAWKKRWFILRSGRMSGDPDVLEYYKNDHSKKPLRI
INLNFCEQVDAGLTFNKKELQDSFVFDIKTSERTFYLVAETEEDMNKWVQSICQICGFNQ
AEESTDSLRNVSSAGHGPRSSPAELSSSSQHLLRERKSSAPSHSSQPTLFTFEPPVSNHM
QPTLSTSAPQEYLYLHQCISRRAENARSASFSQGTRASFLMRSDTAVQKLAQGNGHCVNG
ISGQVHGFYSLPKPSRHNTEFRDSTYDLPRSLASHGHTKGSLTGSETDNEDVYTFKTPSN
TLCREFGDLLVDNMDVPATPLSAYQIPRTFTLDKNHNAMTVATPGDSAIAPPPRPPKPSQ
AETPRWGSPQQRPPISENSRSVAATIPRRNTLPAMDNSRLHRASSCETYEYPQRGGESAG
RSAESMSDGVGSFLPGKMIVGRSDSTNSEDNYVPMNPGSSTLLAMERAGDNSQSVYIPMS
PGAHHFDSLGYPSTTLPVHRGPSRGSEIQPPPVNRNLKPDRKAKPTPLDLRNNTVIDELP
FKSPITKSWSRANHTFNSSSSQYCRPISTQSITSTDSGDSEENYVPMQNPVSASPVPSGT
NSPAPKKSTGSVDYLALDFQPSSPSPHRKPSTSSVTSDEKVDYVQVDKEKTQALQNTMQE
WTDVRQSSEPSKGAKL
NT seq
2031 nt
NT seq
+upstream
nt +downstream
nt
atgagcggcggcggcgacgtggtgtgcaccggctggctgaggaaatcgcctcccgagaag
aagttgaggcgctatgcctggaagaaacgctggtttatcctgcggagtggccggatgagc
ggtgacccagatgttctggaatactacaagaacgatcactccaagaagcctctgcggatc
atcaacctgaacttctgtgagcaggtagatgcaggcctgacctttaacaagaaggagctg
caggatagttttgtgtttgacatcaagaccagtgaacgcaccttttacctggtggctgag
acagaagaggacatgaataagtgggtccagagcatctgccagatctgtggcttcaatcag
gctgaggagagcacagactccctgagaaatgtttcctcagccggtcatggcccccgctct
tctccagctgagctcagcagctctagccagcaccttctccgagagcgcaagtcctcagcc
ccatcacactccagccagccaactctgttcacgtttgaaccccctgtgtcaaaccacatg
cagcccaccttgtccaccagcgcacctcaggagtatctctacttgcaccagtgcataagc
cgaagagcagaaaatgcaaggagtgccagcttctctcagggcaccagagcctcttttctc
atgaggagtgacacagctgtacaaaaacttgcccagggcaatggacactgtgtcaacggg
atcagtggtcaagtccatggcttctatagccttcccaagccgagccggcacaatacagaa
ttcagagacagtacctacgacctcccccgcagcctggcctcccatggccacaccaagggc
agcctcacaggctccgagacagataatgaggatgtgtacaccttcaagacgcccagcaac
accctgtgcagggagttcggggacctcctggtagacaatatggatgttccggccacccca
ctctcagcctaccagatccctaggacattcactctggacaaaaaccacaatgccatgaca
gtggccactcctggggactcagccatagctcccccaccccgcccccccaagccaagtcag
gcagaaacacctcgatggggcagtcctcagcagagaccgccaatcagtgaaaatagcaga
tctgtcgctgccaccatccccagacgcaacaccctccctgcaatggacaacagccgactt
caccgagcttcttcctgtgagacctacgagtacccacagcgtggtggagagagtgcaggc
cggtctgctgaatccatgagtgatggagttggctctttcctgccagggaaaatgattgtg
ggccgatcggacagcaccaattctgaagacaactatgtgcccatgaatccaggttcttcc
accctgttggccatggaacgagcaggtgataattcccagagcgtctacatcccaatgagc
ccaggggcccatcactttgactcacttggctacccatcaacaacccttcctgtgcaccga
ggccccagcagaggaagtgagattcagccaccccctgtcaaccgcaacctcaaacctgat
cggaaagcaaagccaacaccacttgacctgaggaacaacaccgtcatcgatgaactcccc
ttcaagtcacctatcaccaagtcttggtctagggccaaccacaccttcaactccagctcc
tcccagtactgccgccccatctccacccagagcatcaccagcacagactcaggagacagc
gaagagaactatgtccctatgcaaaacccagtgtctgcatctcccgttcccagtggcacg
aacagtcctgcccctaagaagagcaccggcagcgttgattatctggccctggacttccag
ccgagctccccaagcccccaccgcaagccatctacttcatccgtcacctctgatgagaag
gtggactacgttcaggtggacaaggagaagacccaggccctgcagaacaccatgcaggag
tggacagacgtgcggcagtcctcagagccttccaagggtgccaagctgtga
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