Homo sapiens (human): 9879
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Entry
9879 CDS
T01001
Symbol
DDX46, PRPF5, Prp5
Name
(RefSeq) DEAD-box helicase 46
KO
K12811
ATP-dependent RNA helicase DDX46/PRP5 [EC:
5.6.2.7
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03040
Spliceosome
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09121 Transcription
03040 Spliceosome
9879 (DDX46)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03041 Spliceosome [BR:
hsa03041
]
9879 (DDX46)
Enzymes [BR:
hsa01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.7 DEAD-box RNA helicase
9879 (DDX46)
Spliceosome [BR:
hsa03041
]
Complex A
U2 snRNP components
U2 related factors
9879 (DDX46)
Complex B
9879 (DDX46)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DEAD
Helicase_C
KH_12
KH-I_KHDC4-BBP
CdAMP_rec
Motif
Other DBs
NCBI-GeneID:
9879
NCBI-ProteinID:
NP_055644
OMIM:
617848
HGNC:
18681
Ensembl:
ENSG00000145833
UniProt:
Q7L014
Structure
PDB
PDBj
LinkDB
All DBs
Position
5:134758779..134831121
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AA seq
1031 aa
AA seq
DB search
MGRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRS
RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS
KEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME
NIGELKKEIEEMKQGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVK
KFNMRSVKGGGGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDAMEYSSEEEE
VDLQTALTGYQTKQRKLLEPVDHGKIEYEPFRKNFYVEVPELAKMSQEEVNVFRLEMEGI
TVKGKGCPKPIKSWVQCGISMKILNSLKKHGYEKPTPIQTQAIPAIMSGRDLIGIAKTGS
GKTIAFLLPMFRHIMDQRSLEEGEGPIAVIMTPTRELALQITKECKKFSKTLGLRVVCVY
GGTGISEQIAELKRGAEIIVCTPGRMIDMLAANSGRVTNLRRVTYVVLDEADRMFDMGFE
PQVMRIVDNVRPDRQTVMFSATFPRAMEALARRILSKPIEVQVGGRSVVCSDVEQQVIVI
EEEKKFLKLLELLGHYQESGSVIIFVDKQEHADGLLKDLMRASYPCMSLHGGIDQYDRDS
IINDFKNGTCKLLVATSVAARGLDVKHLILVVNYSCPNHYEDYVHRAGRTGRAGNKGYAY
TFITEDQARYAGDIIKALELSGTAVPPDLEKLWSDFKDQQKAEGKIIKKSSGFSGKGFKF
DETEQALANERKKLQKAALGLQDSDDEDAAVDIDEQIESMFNSKKRVKDMAAPGTSSVPA
PTAGNAEKLEIAKRLALRINAQKNLGIESQDVMQQATNAILRGGTILAPTVSAKTIAEQL
AEKINAKLNYVPLEKQEEERQDGGQNESFKRYEEELEINDFPQTARWKVTSKEALQRISE
YSEAAITIRGTYFPPGKEPKEGERKIYLAIESANELAVQKAKAEITRLIKEELIRLQNSY
QPTNKGRYKVL
NT seq
3096 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggagtcacgccactatcgaaaacgatcggcatcccggggtcgctctggaagt
cggtctagaagtcgctcaccctcagacaaaagaagtaaacgtggagatgacagacggtct
agaagtagagatagagataggaggagagagaggtctcgtagcagggataaaagaagatct
cggtcaagggacaggaagcgtctgagacgttccagaagtagagagagagacagaagccga
gagcgaagaagatctcgaagtagagacaggagacgctcaaggagtagaagccggggccgg
cgatcccgatcctccagtcctggaaataaaagcaagaaaactgagaatagatctaggtcc
aaagagaaaactgatggtggggaaagttctaaagagaagaaaaaagacaaagatgacaag
gaggatgaaaaagaaaaagatgctggcaactttgaccagaataagctggaagaagaaatg
agaaagcgaaaagaaagagtagaaaaatggcgagaagagcaacgtaaaaaggctatggaa
aacataggagaactgaaaaaggaaatcgaagagatgaaacaagggaaaaagtggagttta
gaggacgatgatgatgacgaagatgatcctgcagaagctgaaaaggagggaaatgaaatg
gagggtgaggagttagatccattagatgcttacatggaagaagtgaaagaggaagtaaaa
aaatttaacatgagaagtgtaaaaggtggtgggggaaatgaaaagaagtctgggccaacg
gtcacaaaagttgtcactgttgtgacaaccaaaaaagcagttgtggattctgataagaag
aaaggtgagctgatggagaatgaccaggatgccatggagtattcttcagaggaggaagaa
gttgatcttcagacagcccttacagggtatcaaacaaaacagcgaaagcttctagaacca
gttgatcatggaaaaattgagtatgagccatttaggaaaaacttctatgttgaagttcca
gaactagcaaaaatgtctcaagaagaggtaaatgtgtttcgattggaaatggagggcatt
acagttaaaggaaaaggttgccccaaaccaattaaatcctgggtccagtgtggaatttcc
atgaagatcttaaattccctcaagaagcatggctatgaaaagcccacgcccatccaaacc
caagctattcctgctataatgtctggacgagatttgattggcattgccaaaacaggaagt
ggaaagaccattgcttttctgttgcccatgtttagacacatcatggatcagaggtcatta
gaggaaggagaggggccaatagctgtcatcatgactccaactcgagaactggctttacag
attactaaagagtgtaagaagttttccaagactttgggacttagagtggtctgtgtttac
ggaggaacaggaatcagtgagcagattgctgagctgaaaagaggtgctgaaattattgtt
tgcacacctggtcgaatgattgacatgttagccgctaacagtggtcgggtcacaaatctt
cgaagagtgacatatgttgttttagatgaagcagacagaatgtttgacatgggttttgaa
ccccaggtcatgcgcatcgtggataatgttcgtcctgatcgacagacggttatgttttca
gctactttccccagagctatggaggctttggctcgcaggatcctcagtaaacctattgaa
gtacaagttggaggcaggagtgtggtttgctcagatgtggagcaacaagtgattgtgatt
gaagaagaaaagaaattcttgaagttacttgagcttctaggccattatcaagagtcagga
tctgtcattatatttgtggataagcaggaacatgctgatggtcttcttaaggatttaatg
agagcatcttatccttgcatgtctcttcatggaggcattgatcaatatgacagagatagc
atcataaatgactttaagaatgggacctgcaaacttcttgtggctacctctgttgctgcc
cgaggtctagatgtgaaacatctgattcttgtagtaaattatagctgccccaaccattat
gaggattatgtacacagagcagggcggactggaagagcaggaaacaagggttatgcttat
acttttatcacagaggatcaagctcgctatgctggtgacataattaaagctcttgaattg
tcagggactgcagtacctcctgatttagagaaactgtggagtgatttcaaagatcagcag
aaagctgaggggaaaataattaaaaagagtagtgggttctctggtaagggattcaagttt
gatgaaacagaacaagctttggctaatgagaggaagaagttacaaaaagcagctcttggt
ctacaagattcagatgatgaggatgctgcagttgatattgatgagcaaattgaaagcatg
tttaattcaaagaagagagtaaaggatatggctgctcctggaacatcaagtgttcctgct
ccaactgcaggaaatgctgagaaattagaaattgctaagagattggctcttagaatcaat
gcccagaagaatttgggcatcgagtctcaggatgtgatgcagcaggccaccaatgcaatt
cttaggggtggcaccattctggctcccactgtttctgcaaaaaccattgcagaacaactt
gctgaaaagatcaatgccaagctcaattatgtgccgttagagaaacaagaagaagagaga
caggatggtggacagaatgaatcttttaagagatatgaagaagaattagagatcaatgac
ttcccacagactgctaggtggaaagttacctctaaggaagctctgcagagaatcagtgaa
tactctgaagccgcaattacaatcagaggaacctacttccctcctggcaaagaacccaag
gaaggcgagcggaagatttacttggcaattgaaagtgccaatgaactggctgtgcagaaa
gcaaaggcagaaatcaccaggctcataaaagaagagctgatccggctgcaaaattcatac
caaccaacaaataaaggaagatacaaagtcttatag
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