Homo sapiens (human): 9924
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Entry
9924 CDS
T01001
Symbol
PAN2, USP52
Name
(RefSeq) PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform 1
KO
K12571
PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:
3.1.13.4
]
Organism
hsa
Homo sapiens (human)
Pathway
hsa03018
RNA degradation
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
03018 RNA degradation
9924 (PAN2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
hsa03019
]
9924 (PAN2)
Enzymes [BR:
hsa01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.13 Exoribonucleases producing 5'-phosphomonoesters
3.1.13.4 poly(A)-specific ribonuclease
9924 (PAN2)
Messenger RNA biogenesis [BR:
hsa03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
P-body specific factors
9924 (PAN2)
mRNA degradation factors
3'-5' decay
Pan complex
9924 (PAN2)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PAN2_N
UCH_1
RNase_T
UCH
WD40_like
WD40_CDC20-Fz
Beta-prop_THOC3
Beta-prop_NOL10_N
Motif
Other DBs
NCBI-GeneID:
9924
NCBI-ProteinID:
NP_001120932
OMIM:
617447
HGNC:
20074
UniProt:
Q504Q3
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(56316936..56334000)
Genome browser
AA seq
1202 aa
AA seq
DB search
MNFEGLDPGLAEYAPAMHSALDPVLDAHLNPSLLQNVELDPEGVALEALPVQESVHIMEG
VYSELHSVVAEVGVPVSVSHFDLHEEMLWVGSHGGHATSFFGPALERYSSFQVNGSDDIR
QIQSLENGILFLTKNNLKYMARGGLIIFDYLLDENEDMHSLLLTDSSTLLVGGLQNHIIE
IDLNTVQETQKYAVETPGVTIMRQTNRFFFCGHTSGKVSLRDLRTFKVEHEFDAFSGSLS
DFDVHGNLLAACGFSSRLTGLACDRFLKVYDLRMMRAITPLQVHVDPAFLRFIPTYTSRL
AIISQSGQCQFCEPTGLANPADIFHVNPVGPLLMTFDVSASKQALAFGDSEGCVHLWTDS
PEPSFNPYSRETEFALPCLVDSLPPLDWSQDLLPLSLIPVPLTTDTLLSDWPAANSAPAP
RRAPPVDAEILRTMKKVGFIGYAPNPRTRLRNQIPYRLKESDSEFDSFSQVTESPVGREE
EPHLHMVSKKYRKVTIKYSKLGLEDFDFKHYNKTLFAGLEPHIPNAYCNCMIQVLYFLEP
VRCLIQNHLCQKEFCLACELGFLFHMLDLSRGDPCQGNNFLRAFRTIPEASALGLILADS
DEASGKGNLARLIQRWNRFILTQLHQDMQELEIPQAYRGAGGSSFCSSGDSVIGQLFSCE
MENCSLCRCGSETVRASSTLLFTLSYPDGSKSDKTGKNYDFAQVLKRSICLDQNTQAWCD
TCEKYQPTIQTRNIRHLPDILVINCEVNSSKEADFWRMQAEVAFKMAVKKHGGEISKNKE
FALADWKELGSPEGVLVCPSIEELKNVWLPFSIRMKMTKNKGLDVCNWTDGDEMQWGPAR
AEEEHGVYVYDLMATVVHILDSRTGGSLVAHIKVGETYHQRKEGVTHQQWYLFNDFLIEP
IDKHEAVQFDMNWKVPAILYYVKRNLNSRYNLNIKNPIEASVLLAEASLARKQRKTHTTF
IPLMLNEMPQIGDLVGLDAEFVTLNEEEAELRSDGTKSTIKPSQMSVARITCVRGQGPNE
GIPFIDDYISTQEQVVDYLTQYSGIKPGDLDAKISSKHLTTLKSTYLKLRFLIDIGVKFV
GHGLQKDFRVINLMVPKDQVLDTVYLFHMPRKRMISLRFLAWYFLDLKIQGETHDSIEDA
RTALQLYRKYLELSKNGTEPESFHKVLKGLYEKGRKMDWKVPEPEGQTSPKNAAVFSSVL
AL
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgaactttgagggtctggaccctggactggcagaatatgccccagccatgcattctgcc
ctggaccctgtcttggatgcccacctgaacccaagtctgctacagaatgtggagctggac
ccagagggagtggccttggaggctcttcccgtccaggaatcagtgcacataatggaaggt
gtctactctgaattgcacagcgtggtggctgaagtgggtgtacctgtttccgtctcccac
tttgacttgcacgaggagatgctgtgggtggggagccacgggggccatgccacttcattt
tttggcccagccttggagcgctactcatcctttcaagtcaatggcagtgatgatattcgg
cagatccagagcctggagaatggtatcctttttctcaccaagaacaacctcaagtatatg
gcccgtgggggcctcattatatttgattacctgctggatgagaatgaggatatgcacagt
ctcctactgactgacagcagcactctactcgttggtgggctgcagaatcacataatagag
attgatcttaacactgtccaggagactcagaagtatgcagtagagacgcctggagtcacc
atcatgagacagacaaatcgcttcttcttctgcggccacacgtctggcaaggtttccctg
agagacctccgtacttttaaggtggaacatgagtttgatgccttctcaggaagtctgtca
gactttgatgtgcatggcaacctgctagctgcctgtggcttctccagccgcctcactggc
ctggcctgcgaccgtttcctcaaggtgtatgatttgcgcatgatgcgtgccatcacacca
cttcaagtacatgtggatcctgccttcttgcgcttcattcctacatatacttctcgtctt
gctatcatctctcagtcagggcagtgccaattctgtgaacccacaggcctggccaaccca
gccgatatctttcatgtgaatcctgtggggcctctgctaatgacatttgatgtgtcagcc
agcaagcaggctctggcctttggggattctgagggctgtgtgcacctctggactgattcc
ccggagccttccttcaacccctactcccgtgagactgagtttgctttgccgtgtctcgtg
gactcactgcctcctctggactggagccaggacctgctgcctctttccctcatccctgtc
ccactcaccactgacacacttctctctgattggcctgctgccaactctgctccagctccc
aggcgagcaccacccgtggatgcagagattctgcgcaccatgaagaaggtgggcttcatt
ggctatgcgcccaatccccgcaccaggctgcgcaatcagataccctacagactcaaggag
tcagacagtgaatttgacagcttcagccaggtcactgagtcaccagtaggacgagaagag
gaaccacatctccacatggtttctaagaaataccgcaaggtgaccatcaaatattccaag
ctagggctggaggactttgacttcaaacactacaataagaccttgtttgctggattagag
ccccacattcccaacgcctactgtaactgcatgatccaggtgctctatttcctggagcct
gtacgctgtctaattcaaaaccacctttgccagaaggagttctgtctggcatgtgagctg
ggcttcctgtttcacatgttggacctctctcgtggtgacccttgccagggcaataatttt
cttcgggcattccgtactattcctgaggcctcagccctcggtctaatcctggctgactca
gatgaggcctcaggcaagggcaatctggccaggctcattcagaggtggaatcgcttcatt
ctcactcaactgcatcaagatatgcaggagctggaaataccacaggcttatcgaggtgct
ggaggcagcagcttttgctcatcgggggactctgttattgggcagctcttcagctgtgag
atggagaactgcagcctctgccgctgtggcagtgagaccgtgcgagcctcatccactctg
cttttcacactctcctaccctgatggtagcaaaagtgataaaactgggaagaactatgac
tttgctcaggtgctgaagcgaagcatctgcctggaccagaatacacaggcctggtgtgac
acctgtgaaaagtaccagcccacgattcagacccgcaacatccgccatctgccagatatt
cttgtcatcaattgtgaggtgaacagctcaaaagaggctgatttctggagaatgcaggct
gaggttgccttcaagatggcagtaaagaaacacggtggggaaatctccaagaacaaggaa
tttgctttggctgattggaaggaactagggagtccagagggtgtgctggtgtgtccctcc
attgaggagttgaagaacgtctggcttcctttctccattcgcatgaagatgaccaaaaac
aaagggctggatgtttgcaattggactgatggggatgagatgcagtggggcccagccagg
gcagaggaggagcatggtgtctatgtgtatgacctgatggctactgtggtacacatcctg
gactcacgcacagggggcagcctggtggctcacatcaaagttggagagacctaccaccag
cgcaaggagggcgttactcaccagcagtggtatctgttcaatgactttcttattgaacct
attgataagcatgaagctgtgcagtttgacatgaattggaaagtacctgcaatcctttat
tatgtcaaacggaatctcaattccagatacaacctgaacatcaagaaccctattgaggca
agtgtcttgctggctgaagcctcgctggcacggaagcagcggaaaacacatactaccttt
attccactgatgctgaatgagatgccacagattggggacctggtgggtctggatgctgag
tttgtcacccttaatgaggaggaagcagagttacgcagtgatggtaccaagtctaccatt
aaaccaagccagatgtcagtagccaggattacctgtgttcggggccagggacccaatgag
ggtatccccttcattgatgactacatctctacccaggagcaggtggtggattacttgact
caatactcgggtataaagcctggtgacctcgatgccaaaatttcctccaagcacctaaca
actctcaagtctacctacttaaagcttcgttttctcattgacattggagtcaagtttgtg
ggtcatggcctgcagaaggacttccgggtcatcaacctgatggtgcccaaggaccaagtc
cttgacactgtctacctgttccatatgccccgaaaacgaatgatttccctgcgattcctt
gcttggtactttctggacctgaagattcaaggggaaacccatgacagtattgaggatgcc
cgcacagcccttcagctgtaccgaaagtatctggagctaagcaaaaatggcactgagcct
gagtctttccacaaggtgctcaagggtctttatgagaagggcagaaagatggactggaag
gtgcctgagcctgagggccaaacaagtcccaagaatgcagctgtcttctcctcagtgctg
gcgctctga
DBGET
integrated database retrieval system
