Homo sapiens (human): 2243
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Entry
2243 CDS
T01001
Symbol
FGA, AMYLD2, Fib2
Name
(RefSeq) fibrinogen alpha chain
KO
K03903
fibrinogen alpha chain
Organism
hsa
Homo sapiens (human)
Pathway
hsa04610
Complement and coagulation cascades
hsa04611
Platelet activation
hsa04613
Neutrophil extracellular trap formation
hsa05171
Coronavirus disease - COVID-19
Network
nt06171
SARS coronavirus 2 (SARS-CoV-2)
nt06514
Coagulation cascade
Element
N01502
Lectin pathway of coagulation cascade, fibrinogen to fibrin
N01513
Common pathway of coagulation cascade, fibrinogen to fibrin
Disease
H00222
Congenital fibrinogen deficiency
H00223
Inherited thrombophilia
H00845
Familial amyloidosis
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
2243 (FGA)
04611 Platelet activation
2243 (FGA)
04613 Neutrophil extracellular trap formation
2243 (FGA)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
2243 (FGA)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
hsa04147
]
2243 (FGA)
00536 Glycosaminoglycan binding proteins [BR:
hsa00536
]
2243 (FGA)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
2243 (FGA)
Glycosaminoglycan binding proteins [BR:
hsa00536
]
Heparan sulfate / Heparin
Extracellular matrix molecules
2243 (FGA)
Hyaluronan
Extracellular matrix or blood plasma proteins
2243 (FGA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Fibrinogen_C
Fib_alpha
Fibrinogen_aC
Motif
Other DBs
NCBI-GeneID:
2243
NCBI-ProteinID:
NP_000499
OMIM:
134820
HGNC:
3661
Ensembl:
ENSG00000171560
CPD:
C00290
C00952
UniProt:
P02671
Structure
PDB
PDBj
LinkDB
All DBs
Position
4:complement(154583126..154590742)
Genome browser
AA seq
866 aa
AA seq
DB search
MFSMRIVCLVLSVVGTAWTADSGEGDFLAEGGGVRGPRVVERHQSACKDSDWPFCSDEDW
NYKCPSGCRMKGLIDEVNQDFTNRINKLKNSLFEYQKNNKDSHSLTTNIMEILRGDFSSA
NNRDNTYNRVSEDLRSRIEVLKRKVIEKVQHIQLLQKNVRAQLVDMKRLEVDIDIKIRSC
RGSCSRALAREVDLKDYEDQQKQLEQVIAKDLLPSRDRQHLPLIKMKPVPDLVPGNFKSQ
LQKVPPEWKALTDMPQMRMELERPGGNEITRGGSTSYGTGSETESPRNPSSAGSWNSGSS
GPGSTGNRNPGSSGTGGTATWKPGSSGPGSTGSWNSGSSGTGSTGNQNPGSPRPGSTGTW
NPGSSERGSAGHWTSESSVSGSTGQWHSESGSFRPDSPGSGNARPNNPDWGTFEEVSGNV
SPGTRREYHTEKLVTSKGDKELRTGKEKVTSGSTTTTRRSCSKTVTKTVIGPDGHKEVTK
EVVTSEDGSDCPEAMDLGTLSGIGTLDGFRHRHPDEAAFFDTASTGKTFPGFFSPMLGEF
VSETESRGSESGIFTNTKESSSHHPGIAEFPSRGKSSSYSKQFTSSTSYNRGDSTFESKS
YKMADEAGSEADHEGTHSTKRGHAKSRPVRDCDDVLQTHPSGTQSGIFNIKLPGSSKIFS
VYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYKRGFGSLNDEGEGEFWLGNDYLHLLTQR
GSVLRVELEDWAGNEAYAEYHFRVGSEAEGYALQVSSYEGTAGDALIEGSVEEGAEYTSH
NNMQFSTFDRDADQWEENCAEVYGGGWWYNNCQAANLNGIYYPGGSYDPRNNSPYEIENG
VVWVSFRGADYSLRAVRMKIRPLVTQ
NT seq
2601 nt
NT seq
+upstream
nt +downstream
nt
atgttttccatgaggatcgtctgcctggtcctaagtgtggtgggcacagcatggactgca
gatagtggtgaaggtgactttctagctgaaggaggaggcgtgcgtggcccaagggttgtg
gaaagacatcaatctgcctgcaaagattcagactggcccttctgctctgatgaagactgg
aactacaaatgcccttctggctgcaggatgaaagggttgattgatgaagtcaatcaagat
tttacaaacagaataaataagctcaaaaattcactatttgaatatcagaagaacaataag
gattctcattcgttgaccactaatataatggaaattttgagaggcgatttttcctcagcc
aataaccgtgataatacctacaaccgagtgtcagaggatctgagaagcagaattgaagtc
ctgaagcgcaaagtcatagaaaaagtacagcatatccagcttctgcagaaaaatgttaga
gctcagttggttgatatgaaacgactggaggtggacattgatattaagatccgatcttgt
cgagggtcatgcagtagggctttagctcgtgaagtagatctgaaggactatgaagatcag
cagaagcaacttgaacaggtcattgccaaagacttacttccctctagagataggcaacac
ttaccactgataaaaatgaaaccagttccagacttggttcccggaaattttaagagccag
cttcagaaggtacccccagagtggaaggcattaacagacatgccgcagatgagaatggag
ttagagagacctggtggaaatgagattactcgaggaggctccacctcttatggaaccgga
tcagagacggaaagccccaggaaccctagcagtgctggaagctggaactctgggagctct
ggacctggaagtactggaaaccgaaaccctgggagctctgggactggagggactgcaacc
tggaaacctgggagctctggacctggaagtactggaagctggaactctgggagctctgga
actggaagtactggaaaccaaaaccctgggagccctagacctggtagtaccggaacctgg
aatcctggcagctctgaacgcggaagtgctgggcactggacctctgagagctctgtatct
ggtagtactggacaatggcactctgaatctggaagttttaggccagatagcccaggctct
gggaacgcgaggcctaacaacccagactggggcacatttgaagaggtgtcaggaaatgta
agtccagggacaaggagagagtaccacacagaaaaactggtcacttctaaaggagataaa
gagctcaggactggtaaagagaaggtcacctctggtagcacaaccaccacgcgtcgttca
tgctctaaaaccgttactaagactgttattggtcctgatggtcacaaagaagttaccaaa
gaagtggtgacctccgaagatggttctgactgtcccgaggcaatggatttaggcacattg
tctggcataggtactctggatgggttccgccataggcaccctgatgaagctgccttcttc
gacactgcctcaactggaaaaacattcccaggtttcttctcacctatgttaggagagttt
gtcagtgagactgagtctaggggctcagaatctggcatcttcacaaatacaaaggaatcc
agttctcatcaccctgggatagctgaattcccttcccgtggtaaatcttcaagttacagc
aaacaatttactagtagcacgagttacaacagaggagactccacatttgaaagcaagagc
tataaaatggcagatgaggccggaagtgaagccgatcatgaaggaacacatagcaccaag
agaggccatgctaaatctcgccctgtcagagactgtgatgatgtcctccaaacacatcct
tcaggtacccaaagtggcattttcaatatcaagctaccgggatccagtaagattttttct
gtttattgcgatcaagagaccagtttgggaggatggcttttgatccagcaaagaatggat
ggatcactgaattttaaccggacctggcaagactacaagagaggtttcggcagcctgaat
gacgagggggaaggagaattctggctaggcaatgactacctccacttactaacccaaagg
ggctctgttcttagggttgaattagaggactgggctgggaatgaagcttatgcagaatat
cacttccgggtaggctctgaggctgaaggctatgccctccaagtctcctcctatgaaggc
actgcgggtgatgctctgattgagggttccgtagaggaaggggcagagtacacctctcac
aacaacatgcagttcagcacctttgacagggatgcagaccagtgggaagagaactgtgca
gaagtctatgggggaggctggtggtataataactgccaagcagccaatctcaatggaatc
tactaccctgggggctcctatgacccaaggaataacagtccttatgagattgagaatgga
gtggtctgggtttcctttagaggggcagattattccctcagggctgttcgcatgaaaatt
aggccccttgtgacccaatag
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integrated database retrieval system
