Homo sapiens (human): 3849
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Entry
3849 CDS
T01001
Symbol
KRT2, CK-2e, K2e, KRT2A, KRT2E, KRTE
Name
(RefSeq) keratin 2
KO
K07605
type II keratin, basic
Organism
hsa
Homo sapiens (human)
Pathway
hsa04382
Cornified envelope formation
Network
nt06545
Cornified envelope formation
Element
N01930
Processing of profilaggrin to filaggrin and binding to keratin filaments
Disease
H00693
Ichthyosis bullosa of Siemens
Brite
KEGG Orthology (KO) [BR:
hsa00001
]
09150 Organismal Systems
09158 Development and regeneration
04382 Cornified envelope formation
3849 (KRT2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
hsa04812
]
3849 (KRT2)
04147 Exosome [BR:
hsa04147
]
3849 (KRT2)
Cytoskeleton proteins [BR:
hsa04812
]
Eukaryotic cytoskeleton proteins
Intermediate filaments
Intermediate filaments
Types I and II: Acidic and basic keratins
3849 (KRT2)
Exosome [BR:
hsa04147
]
Exosomal proteins
Exosomal proteins of epithelial cells
3849 (KRT2)
Exosomal proteins of other body fluids (saliva and urine)
3849 (KRT2)
Exosomal proteins of colorectal cancer cells
3849 (KRT2)
Exosomal proteins of bladder cancer cells
3849 (KRT2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Filament
Keratin_2_head
TPR_MLP1_2
FlgN
Nuf2_DHR10-like
SlyX
CENP-F_leu_zip
Alanine_zipper
DUF745
DUF948
COG6_N
Mce4_CUP1
DUF1192
Motif
Other DBs
NCBI-GeneID:
3849
NCBI-ProteinID:
NP_000414
OMIM:
600194
HGNC:
6439
Ensembl:
ENSG00000172867
UniProt:
P35908
LinkDB
All DBs
Position
12:complement(52644558..52652211)
Genome browser
AA seq
639 aa
AA seq
DB search
MSCQISCKSRGRGGGGGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGS
RSLVGLGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGG
GRFGGFGGPGGVGGLGGPGGFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQERE
QIKTLNNKFASFIDKVRFLEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYL
DGLTAERTSQNSELNNMQDLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQ
SKVDLLNQEIEFLKVLYDAEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIA
QRSKEEAEALYHSKYEELQVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNV
QDAIADAEQRGEHALKDARNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATY
RKLLEGEECRMSGDLSSNVTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYG
SGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGG
GSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFSFR
NT seq
1920 nt
NT seq
+upstream
nt +downstream
nt
atgagttgtcagatctcttgcaaatctcgaggaagaggaggaggtggaggaggattccgg
ggcttcagcagcggctcagctgtggtgtctggtggaagccggagatcaacttccagcttc
tcctgcttgagccgccatggtggtggtggcgggggcttcggtggaggcggctttggcagt
cggagtcttgttggccttggagggaccaagagcatctccattagtgtggctggaggaggt
ggtggctttggcgccgctggtggatttggtggcagaggaggtggttttggaggcggcagc
agctttggaggtggcagcggcttcagtggtggtggtttcggtggaggcggctttggtgga
ggccgctttggaggttttgggggccctggtggtgttggaggtttagggggtcctggtggc
tttgggcctggaggataccctggtggcatccacgaagtctctgtcaaccagagcctcctg
cagcctctcaacgtgaaagttgacccagagatccagaatgtgaaggcccaagagcgtgag
cagatcaaaactctcaacaacaaatttgcctccttcattgacaaggtgcggttcttggag
cagcagaaccaggtgttacagaccaaatgggagctgctacaacaaatgaatgttggcacc
cgccccatcaacctggagcccatcttccaggggtatatcgacagcctcaagagatatctg
gatgggctcactgcagaaagaacatcacagaattcagagctgaataacatgcaggatctt
gtggaggattataagaagaagtatgaggatgaaatcaataagcgcacagctgctgagaat
gattttgtgacgcttaaaaaggacgtggacaatgcctacatgataaaggtggagttgcag
tccaaggtggacctgctgaaccaggaaattgagtttctgaaagttctctatgatgcggag
atatcccagatacatcagagtgtcactgacaccaacgtcatcctctccatggacaacagc
cgcaacctggacttggatagcatcatcgccgaggtcaaggcccagtatgaggagatcgcc
cagaggagcaaggaagaagcggaggccctgtaccacagcaagtatgaggagctccaggtg
actgtcgggagacatggagacagcctgaaagagatcaagatagagatcagcgagctgaac
cgcgtgatccagaggctgcagggggagatcgcacatgtgaagaagcagtgtaagaatgtg
caagatgccatcgcagatgccgagcagcgtggggagcatgccctcaaggatgccaggaac
aagttgaatgacctggaggaggccctgcagcaggccaaggaggacttggcgcggctgctg
cgtgactaccaggagctgatgaacgtgaagctggccctagatgtggagatcgccacctac
cgcaaactgctggagggcgaggagtgcaggatgtctggagacctcagcagcaatgtgact
gtgtctgtgacaagcagcaccatttcatcaaatgtggcatccaaggctgcctttggaggt
tctggaggtagagggtccagttccggaggaggatacagctctggaagcagcagttatggc
tctggaggccgacagtctggctccagaggcggtagtggaggaggaggttctatctctgga
ggaggatatggctctggcggtggttctggaggaagatacggatctggtggtggctctaag
ggagggtccatctctggaggaggatatggctctggaggtggaaaacacagctctggaggt
ggctctagaggaggctccagctctggaggaggatatggctctggaggtgggggttctagc
tctgtaaagggtagctcaggtgaagcttttggttccagcgtgaccttctcttttagataa
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integrated database retrieval system
