Homo sapiens (human): 4703 Help Entry 4703              CDS       T01001                                  Symbol NEB, AMC6, NEB177D, NEM2 Name (RefSeq) nebulin   KO K18267   nebulin Organism hsa  Homo sapiens (human) Pathway hsa04820   Cytoskeleton in muscle cells Network nt06539  Cytoskeleton in muscle cells   Element N01819   Actin thin filament, length regulation Disease H00698   Nemaline myopathy H02299   Arthrogryposis multiplex congenita Brite KEGG Orthology (KO) [BR:hsa00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     4703 (NEB)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:hsa04147]     4703 (NEB) Exosome [BR:hsa04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)     4703 (NEB) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Nebulin Peptidase_M24 SH3_9 SH3_1 SH3_2 Motif Other DBs NCBI-GeneID:  4703 NCBI-ProteinID:  NP_001157979 OMIM:  161650 HGNC:  7720 Ensembl:  ENSG00000183091 UniProt:  P20929 Structure PDBPDBj LinkDB All DBs Position 2:complement(151485339..151734476) Genome browser AA seq 8525 aa AA seqDB search MADDEDYEEVVEYYTEEVVYEEVPGETITKIYETTTTRTSDYEQSETSKPALAQPALAQP ASAKPVERRKVIRKKVDPSKFMTPYIAHSQKMQDLFSPNKYKEKFEKTKGQPYASTTDTP ELRRIKKVQDQLSEVKYRMDGDVAKTICHVDEKAKDIEHAKKVSQQVSKVLYKQNWEDTK DKYLLPPDAPELVQAVKNTAMFSKKLYTEDWEADKSLFYPYNDSPELRRVAQAQKALSDV AYKKGLAEQQAQFTPLADPPDIEFAKKVTNQVSKQKYKEDYENKIKGKWSETPCFEVANA RMNADNISTRKYQEDFENMKDQIYFMQTETPEYKMNKKAGVAASKVKYKEDYEKNKGKAD YNVLPASENPQLRQLKAAGDALSDKLYKENYEKTKAKSINYCETPKFKLDTVLQNFSSDK KYKDSYLKDILGHYVGSFEDPYHSHCMKVTAQNSDKNYKAEYEEDRGKGFFPQTITQEYE AIKKLDQCKDHTYKVHPDKTKFTQVTDSPVLLQAQVNSKQLSDLNYKAKHESEKFKCHIP PDTPAFIQHKVNAYNLSDNLYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTSDVMYKKD YEKNKGKMIGVLSINDDPKMLHSLKVAKNQSDRLYKENYEKTKAKSMNYCETPKYQLDTQ LKNFSEARYKDLYVKDVLGHYVGSMEDPYHTHCMKVAAQNSDKSYKAEYEEDKGKCYFPQ TITQEYEAIKKLDQCKDHTYKVHPDKTKFTAVTDSPVLLQAQLNTKQLSDLNYKAKHEGE KFKCHIPADAPQFIQHRVNAYNLSDNVYKQDWEKSKAKKFDIKVDAIPLLAAKANTKNTS DVMYKKDYEKSKGKMIGALSINDDPKMLHSLKTAKNQSDREYRKDYEKSKTIYTAPLDML QVTQAKKSQAIASDVDYKHILHSYSYPPDSINVDLAKKAYALQSDVEYKADYNSWMKGCG WVPFGSLEMEKAKRASDILNEKKYRQHPDTLKFTSIEDAPITVQSKINQAQRSDIAYKAK GEEIIHKYNLPPDLPQFIQAKVNAYNISENMYKADLKDLSKKGYDLRTDAIPIRAAKAAR QAASDVQYKKDYEKAKGKMVGFQSLQDDPKLVHYMNVAKIQSDREYKKDYEKTKSKYNTP HDMFNVVAAKKAQDVVSNVNYKHSLHHYTYLPDAMDLELSKNMMQIQSDNVYKEDYNNWM KGIGWIPIGSLDVEKVKKAGDALNEKKYRQHPDTLKFTSIVDSPVMVQAKQNTKQVSDIL YKAKGEDVKHKYTMSPDLPQFLQAKCNAYNISDVCYKRDWYDLIAKGNNVLGDAIPITAA KASRNIASDYKYKEAYEKSKGKHVGFRSLQDDPKLVHYMNVAKLQSDREYKKNYENTKTS YHTPGDMVSITAAKMAQDVATNVNYKQPLHHYTYLPDAMSLEHTRNVNQIQSDNVYKDEY NSFLKGIGWIPIGSLEVEKVKKAGDALNERKYRQHPDTVKFTSVPDSMGMVLAQHNTKQL SDLNYKVEGEKLKHKYTIDPELPQFIQAKVNALNMSDAHYKADWKKTIAKGYDLRPDAIP IVAAKSSRNIASDCKYKEAYEKAKGKQVGFLSLQDDPKLVHYMNVAKIQSDREYKKGYEA SKTKYHTPLDMVSVTAAKKSQEVATNANYRQSYHHYTLLPDALNVEHSRNAMQIQSDNLY KSDFTNWMKGIGWVPIESLEVEKAKKAGEILSEKKYRQHPEKLKFTYAMDTMEQALNKSN KLNMDKRLYTEKWNKDKTTIHVMPDTPDILLSRVNQITMSDKLYKAGWEEEKKKGYDLRP DAIAIKAARASRDIASDYKYKKAYEQAKGKHIGFRSLEDDPKLVHFMQVAKMQSDREYKK GYEKSKTSFHTPVDMLSVVAAKKSQEVATNANYRNVIHTYNMLPDAMSFELAKNMMQIQS DNQYKADYADFMKGIGWLPLGSLEAEKNKKAMEIISEKKYRQHPDTLKYSTLMDSMNMVL AQNNAKIMNEHLYKQAWEADKTKVHIMPDIPQIILAKANAINMSDKLYKLSLEESKKKGY DLRPDAIPIKAAKASRDIASDYKYKYNYEKGKGKMVGFRSLEDDPKLVHSMQVAKMQSDR EYKKNYENTKTSYHTPADMLSVTAAKDAQANITNTNYKHLIHKYILLPDAMNIELTRNMN RIQSDNEYKQDYNEWYKGLGWSPAGSLEVEKAKKATEYASDQKYRQHPSNFQFKKLTDSM DMVLAKQNAHTMNKHLYTIDWNKDKTKIHVMPDTPDILQAKQNQTLYSQKLYKLGWEEAL KKGYDLPVDAISVQLAKASRDIASDYKYKQGYRKQLGHHVGFRSLQDDPKLVLSMNVAKM QSEREYKKDFEKWKTKFSSPVDMLGVVLAKKCQELVSDVDYKNYLHQWTCLPDQNDVVQA KKVYELQSENLYKSDLEWLRGIGWSPLGSLEAEKNKRASEIISEKKYRQPPDRNKFTSIP DAMDIVLAKTNAKNRSDRLYREAWDKDKTQIHIMPDTPDIVLAKANLINTSDKLYRMGYE ELKRKGYDLPVDAIPIKAAKASREIASEYKYKEGFRKQLGHHIGARNIEDDPKMMWSMHV AKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQSDV IHARQAYDLQSDNLYKSDLQWLKGIGWMTSGSLEDEKNKRATQILSDHVYRQHPDQFKFS SLMDSIPMVLAKNNAITMNHRLYTEAWDKDKTTVHIMPDTPEVLLAKQNKVNYSEKLYKL GLEEAKRKGYDMRVDAIPIKAAKASRDIASEFKYKEGYRKQLGHHIGARAIRDDPKMMWS MHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHQWTCLPDQ SDVIHARQAYDLQSDNMYKSDLQWMRGIGWVSIGSLDVEKCKRATEILSDKIYRQPPDRF KFTSVTDSLEQVLAKNNAITMNKRLYTEAWDKDKTQIHIMPDTPEIMLARMNKINYSESL YKLANEEAKKKGYDLRSDAIPIVAAKASRDIISDYKYKDGYCKQLGHHIGARNIEDDPKM MWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEWTCL PDQSDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRATEILSDNIYRQPP DKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQIHIMPDTPEIMLARQNKINYS ETLYKLANEEAKKKGYDLRSDAIPIVAAKASRDVISDYKYKDGYRKQLGHHIGARNIEDD PKMMWSMHVAKIQSDREYKKDFEKWKTKFSSPVDMLGVVLAKKCQTLVSDVDYKNYLHEW TCLPDQNDVIHARQAYDLQSDNIYKSDLQWLRGIGWVPIGSMDVVKCKRAAEILSDNIYR QPPDKLKFTSVTDSLEQVLAKNNALNMNKRLYTEAWDKDKTQVHIMPDTPEIMLARQNKI NYSESLYRQAMEEAKKEGYDLRSDAIPIVAAKASRDIASDYKYKEAYRKQLGHHIGARAV HDDPKIMWSLHIAKVQSDREYKKDFEKYKTRYSSPVDMLGIVLAKKCQTLVSDVDYKHPL HEWICLPDQNDIIHARKAYDLQSDNLYKSDLEWMKGIGWVPIDSLEVVRAKRAGELLSDT IYRQRPETLKFTSITDTPEQVLAKNNALNMNKRLYTEAWDNDKKTIHVMPDTPEIMLAKL NRINYSDKLYKLALEESKKEGYDLRLDAIPIQAAKASRDIASDYKYKEGYRKQLGHHIGA RNIKDDPKMMWSIHVAKIQSDREYKKEFEKWKTKFSSPVDMLGVVLAKKCQILVSDIDYK HPLHEWTCLPDQNDVIQARKAYDLQSDAIYKSDLEWLRGIGWVPIGSVEVEKVKRAGEIL SDRKYRQPADQLKFTCITDTPEIVLAKNNALTMSKHLYTEAWDADKTSIHVMPDTPDILL AKSNSANISQKLYTKGWDESKMKDYDLRADAISIKSAKASRDIASDYKYKEAYEKQKGHH IGAQSIEDDPKIMCAIHAGKIQSEREYKKEFQKWKTKFSSPVDMLSILLAKKCQTLVTDI DYRNYLHEWTCMPDQNDIIQAKKAYDLQSDSVYKADLEWLRGIGWMPEGSVEMNRVKVAQ DLVNERLYRTRPEALSFTSIVDTPEVVLAKANSLQISEKLYQEAWNKDKSNITIPSDTPE MLQAHINALQISNKLYQKDWNDAKQKGYDIRADAIEIKHAKASREIASEYKYKEGYRKQL GHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAKKCQVLV SDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSVEVMRVK NAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRDAWEKEKANVNVPAD TPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYLYKTAYE KQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSISAAKEGQ ALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDSVYKADLEWLRGIGWMPEGSVEMN RVKVAQDLVNERLYRTRPEALSFTSIVDTPEVVLAKANSLQISEKLYQEAWNKDKSNITI PSDTPEMLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIASEYKYKE GYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMMSIVQAK KCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGWLPEGSV EVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRNAWEKEKAN VNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRDIASDYL YKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPVDMVSIS AAKEGQALASDVDYRHYLHHWSCFPDQNDVIQARKAYDLQSDSVYKADLEWLRGIGWMPE GSVEMNRVKVAQDLVNERLYRTRPEALSFTSIVDTPEVVLAKANSLQISEKLYQEAWNKD KSNITIPSDTPEMLQAHINALQISNKLYQKDWNDTKQKGYDIRADAIEIKHAKASREIAS EYKYKEGYRKQLGHHMGFRTLQDDPKSVWAIHAAKIQSDREYKKAYEKSKGIHNTPLDMM SIVQAKKCQVLVSDIDYRNYLHQWTCLPDQNDVIQAKKAYDLQSDNLYKSDLEWLKGIGW LPEGSVEVMRVKNAQNLLNERLYRIKPEALKFTSIVDTPEVIQAKINAVQISEPLYRDAW EKEKANVNVPADTPLMLQSKINALQISNKRYQQAWEDVKMTGYDLRADAIGIQHAKASRD IASDYLYKTAYEKQKGHYIGCRSAKEDPKLVWAANVLKMQNDRLYKKAYNDHKAKISIPV DMVSISAAKEGQALASDVDYRHYLHRWSCFPDQNDVIQARKAYDLQSDALYKADLEWLRG IGWMPQGSPEVLRVKNAQNIFCDSVYRTPVVNLKYTSIVDTPEVVLAKSNAENISIPKYR EVWDKDKTSIHIMPDTPEINLARANALNVSNKLYREGWDEMKAGCDVRLDAIPIQAAKAS REIASDYKYKLDHEKQKGHYVGTLTARDDNKIRWALIADKLQNEREYRLDWAKWKAKIQS PVDMLSILHSKNSQALVSDMDYRNYLHQWTCMPDQNDVIQAKKAYELQSDNVYKADLEWL RGIGWMPNDSVSVNHAKHAADIFSEKKYRTKIETLNFTPVDDRVDYVTAKQSGEILDDIK YRKDWNATKSKYTLTETPLLHTAQEAARILDQYLYKEGWERQKATGYILPPDAVPFVHAH HCNDVQSELKYKAEHVKQKGHYVGVPTMRDDPKLVWFEHAGQIQNERLYKEDYHKTKAKI NIPADMVSVLAAKQGQTLVSDIDYRNYLHQWMCHPDQNDVIQARKAYDLQSDNVYRADLE WLRGIGWIPLDSVDHVRVTKNQEMMSQIKYKKNALENYPNFRSVVDPPEIVLAKINSVNQ SDVKYKETFNKAKGKYTFSPDTPHISHSKDMGKLYSTILYKGAWEGTKAYGYTLDERYIP IVGAKHADLVNSELKYKETYEKQKGHYLAGKVIGEFPGVVHCLDFQKMRSALNYRKHYED TKANVHIPNDMMNHVLAKRCQYILSDLEYRHYFHQWTSLLEEPNVIRVRNAQEILSDNVY KDDLNWLKGIGCYVWDTPQILHAKKSYDLQSQLQYTAAGKENLQNYNLVTDTPLYVTAVQ SGINASEVKYKENYHQIKDKYTTVLETVDYDRTRNLKNLYSSNLYKEAWDRVKATSYILP SSTLSLTHAKNQKHLASHIKYREEYEKFKALYTLPRSVDDDPNTARCLRVGKLNIDRLYR SVYEKNKMKIHIVPDMVEMVTAKDSQKKVSEIDYRLRLHEWICHPDLQVNDHVRKVTDQI SDIVYKDDLNWLKGIGCYVWDTPEILHAKHAYDLRDDIKYKAHMLKTRNDYKLVTDTPVY VQAVKSGKQLSDAVYHYDYVHSVRGKVAPTTKTVDLDRALHAYKLQSSNLYKTSLRTLPT GYRLPGDTPHFKHIKDTRYMSSYFKYKEAYEHTKAYGYTLGPKDVPFVHVRRVNNVTSER LYRELYHKLKDKIHTTPDTPEIRQVKKTQEAVSELIYKSDFFKMQGHMISLPYTPQVIHC RYVGDITSDIKYKEDLQVLKGFGCFLYDTPDMVRSRHLRKLWSNYLYTDKARKMRDKYKV VLDTPEYRKVQELKTHLSELVYRAAGKKQKSIFTSVPDTPDLLRAKRGQKLQSQYLYVEL ATKERPHHHAGNQTTALKHAKDVKDMVSEKKYKIQYEKMKDKYTPVPDTPILIRAKRAYW NASDLRYKETFQKTKGKYHTVKDALDIVYHRKVTDDISKIKYKENYMSQLGIWRSIPDRP EHFHHRAVTDTVSDVKYKEDLTWLKGIGCYAYDTPDFTLAEKNKTLYSKYKYKEVFERTK SDFKYVADSPINRHFKYATQLMNEKKYRADYEQRKDKYHLVVDEPRHLLAKTAGDQISQI KYRKNYEKSKDKFTSIVDTPEHLRTTKVNKQISDILYKLEYNKAKPRGYTTIHDTPMLLH VRKVKDEVSDLKYKEVYQRNKSNCTIEPDAVHIKAAKDAYKVNTNLDYKKQYEANKAHWK WTPDRPDFLQAAKSSLQQSDFEYKLDREFLKGCKLSVTDDKNTVLALRNTLIESDLKYKE KHVKERGTCHAVPDTPQILLAKTVSNLVSENKYKDHVKKHLAQGSYTTLPETRDTVHVKE VTKHVSDTNYKKKFVKEKGKSNYSIMLEPPEVKHAMEVAKKQSDVAYRKDAKENLHYTTV ADRPDIKKATQAAKQASEVEYRAKHRKEGSHGLSMLGRPDIEMAKKAAKLSSQVKYRENF DKEKGKTPKYNPKDSQLYKVMKDANNLASEVKYKADLKKLHKPVTDMKESLIMNHVLNTS QLASSYQYKKKYEKSKGHYHTIPDNLEQLHLKEATELQSIVKYKEKYEKERGKPMLDFET PTYITAKESQQMQSGKEYRKDYEESIKGRNLTGLEVTPALLHVKYATKIASEKEYRKDLE ESIRGKGLTEMEDTPDMLRAKNATQILNEKEYKRDLELEVKGRGLNAMANETPDFMRARN ATDIASQIKYKQSAEMEKANFTSVVDTPEIIHAQQVKNLSSQKKYKEDAEKSMSYYETVL DTPEIQRVRENQKNFSLLQYQCDLKNSKGKITVVQDTPEILRVKENQKNFSSVLYKEDVS PGTAIGKTPEMMRVKQTQDHISSVKYKEAIGQGTPIPDLPEVKRVKETQKHISSVMYKEN LGTGIPTTVTPEIERVKRNQENFSSVLYKENLGKGIPTPITPEMERVKRNQENFSSILYK ENLSKGTPLPVTPEMERVKLNQENFSSVLYKENVGKGIPIPITPEMERVKHNQENFSSVL YKENLGTGIPIPITPEMQRVKHNQENLSSVLYKENMGKGTPLPVTPEMERVKHNQENISS VLYKENMGKGTPLPVTPEMERVKHNQENISSVLYKENMGKGTPLAVTPEMERVKHNQENI SSVLYKENVGKATATPVTPEMQRVKRNQENISSVLYKENLGKATPTPFTPEMERVKRNQE NFSSVLYKENMRKATPTPVTPEMERAKRNQENISSVLYSDSFRKQIQGKAAYVLDTPEMR RVRETQRHISTVKYHEDFEKHKGCFTPVVTDPITERVKKNMQDFSDINYRGIQRKVVEME QKRNDQDQETITGLRVWRTNPGSVFDYDPAEDNIQSRSLHMINVQAQRRSREQSRSASAL SISGGEEKSEHSEAPDHHLSTYSDGGVFAVSTAYKHAKTTELPQQRSSSVATQQTTVSSI PSHPSTAGKIFRAMYDYMAADADEVSFKDGDAIINVQAIDEGWMYGTVQRTGRTGMLPAN YVEAI NT seq 25578 nt NT seq  +upstreamnt  +downstreamnt atggcagatgacgaagactatgaggaggtggtggagtactacacagaagaagtggtttac gaagaggtgccgggagagacaataacaaaaatttatgagactacgacaacaaggacatct gactatgagcaatcagaaacttccaaaccagctctggcacagccagcactggcacagcca gcatcagcaaagccggtggagaggaggaaggtcatccggaagaaagtggatccttcaaag ttcatgaccccctacattgcacacagtcagaaaatgcaggatctttttagcccaaataaa tacaaggagaagtttgagaaaacaaaaggacagccatacgccagcacaacagatactcca gaacttcgcagaatcaaaaaagtacaagatcaactcagtgaggttaagtatcgaatggat ggtgatgttgctaagactatatgtcacgtagatgaaaaagcaaaggatattgaacatgca aagaaagtgtcgcagcaagtcagtaaggttttatacaagcagaactgggaagacaccaag gataagtacctgcttcctcctgatgcccctgaacttgtccaggccgttaagaacaccgcc atgttcagcaagaaactgtacactgaagactgggaagcagacaaaagtttgttttacccc tataatgatagcccggaactgaggagagttgcccaggcccagaaagctctcagtgatgtt gcctacaaaaaaggtctcgctgaacagcaagctcaattcacgcctctggctgatcctcca gatatagaatttgccaagaaagtaaccaatcaagtgagcaagcaaaaatacaaagaagac tatgaaaataaaatcaaaggcaaatggagtgagacaccttgctttgaagttgcaaatgcc agaatgaatgctgataacattagcacaaggaaataccaggaagattttgaaaacatgaaa gaccagatctacttcatgcagaccgaaacaccagagtataaaatgaataaaaaagctggt gtggcagctagcaaggtaaaatacaaagaagactatgaaaagaataaaggaaaagcagat tataatgtgcttcctgcttcagagaacccacagcttaggcagctgaaggcagcaggagat gccctaagtgacaaactatacaaggaaaactatgaaaagacaaaagcaaagagcataaat tactgcgagacccccaaattcaagctcgatactgttctgcagaacttcagtagtgataaa aaatataaagattcctacttaaaagatattttgggacattatgtaggcagcttcgaggat ccataccattcacactgcatgaaagtcacagctcaaaacagtgataaaaactacaaagca gaatacgaagaagacagaggcaaaggcttcttccctcagaccataactcaagaatatgaa gcaattaagaaactagatcagtgtaaagaccacacctacaaagtccatccagataagaca aaattcacccaagttacagactctcctgttctgctacaagcccaagtcaattccaaacaa ctgagtgacttaaattacaaagcaaaacatgaaagtgaaaagttcaagtgccatatcccc cctgatactcctgcttttatccagcacaaagtcaatgcctataacttgagtgataatctt tataagcaagactgggagaagagcaaagccaaaaagtttgacattaaagtggatgccatt cccctgctggcagccaaagccaacaccaagaacaccagcgatgtgatgtacaagaaagac tatgaaaaaaacaaagggaaaatgattggagtcctcagcattaatgacgatcccaagatg ctgcactccttgaaggtggccaaaaaccagagtgatagattatacaaggaaaactatgag aagacaaaggcaaagagtatgaattactgtgagaccccaaaatatcaacttgatactcag ctgaagaacttcagtgaggctagatataaagacttatatgtaaaggatgttttgggacat tatgtaggcagcatggaggacccatatcacacacactgcatgaaagttgcagctcaaaac agtgataaaagttacaaagcagaatatgaagaagataaaggaaaatgctatttccctcag acaataacacaagaatatgaagcaatcaagaagctggaccagtgtaaagatcatacctac aaagttcatccagataagaccaaattcacggcagtcactgattctcctgtactgttgcaa gcccagctcaacacgaaacagcttagtgatctgaattacaaagcaaaacatgaaggtgag aagttcaagtgccatataccagcagatgctccacagtttatccaacacagagtcaatgcc tataatctgagtgataatgtttataagcaagactgggagaagagcaaagccaagaagttt gacattaaagtggacgccattcccctgttggcagccaaagccaacaccaagaacaccagc gatgtgatgtacaagaaagactatgaaaagagcaaagggaaaatgattggagccctcagc attaatgacgatccaaagatgctgcactccttgaagacagccaaaaaccagagtgatcgc gaatatcgaaaagattatgaaaagtcaaaaactatctacacggcacctcttgatatgctc caagtcactcaagctaagaaatctcaggcaattgccagcgacgttgattataagcacatc ttacacagttacagctacccccctgatagcatcaatgtggaccttgccaagaaggcatat gcgctgcagagcgatgttgaatacaaagctgactacaatagctggatgaaaggttgtggc tgggtgccttttgggtccttagaaatggaaaaggcaaagcgagcttcagacatcctcaat gagaaaaaatatcgccaacatccagacaccctcaagtttacctcgattgaagatgctcca attacagtacagtctaaaattaaccaggcccagaggagtgatatcgcttacaaagccaaa ggagaggaaattattcacaaatacaacctgccaccagacctgccccagttcatccaggct aaagttaatgcctacaatatcagtgagaatatgtacaaagcagacttgaaagacttgagc aagaagggatatgacctgagaactgatgcgattcccatcagagctgccaaagctgccagg caggcggcgagtgacgttcagtacaaaaaagactatgaaaaggctaaagggaaaatggtt ggcttccaaagtcttcaagatgaccctaaactggttcattatatgaacgtggccaagata caatcagatcgggagtataaaaaagactatgagaagacaaagtccaaatacaacacgccc catgatatgttcaatgtcgtggcggctaagaaagcccaggatgtggtcagcaatgtcaac tataagcattctctccatcattacacctacttgcctgacgccatggacctggagctgtct aagaacatgatgcagatacagagtgataacgtctacaaggaagactacaacaactggatg aaaggcattggctggattcctattggcagtctcgacgtcgaaaaagttaaaaaggccggt gatgctctgaatgaaaagaagtacaggcaacatccagacaccctcaaatttaccagcatt gtggactccccagttatggtccaggcaaaacagaacacgaagcaagtcagtgatatctta tacaaggctaaaggagaagatgtgaaacataaatacaccatgagtcctgatcttcctcag tttctccaggccaagtgcaatgcttacaatataagtgacgtctgttataaacgggattgg tatgacttaatagccaagggcaacaatgtgctgggcgatgctattcccatcactgcagcc aaggcatcgagaaacattgccagtgattataaatacaaggaagcttatgagaagtcaaag ggaaagcatgtgggtttcagaagcctccaggatgatcccaagctggtccactatatgaat gtggcaaagctgcagtctgatcgtgaatacaagaagaactatgagaacaccaaaaccagc taccatacccctggggacatggttagcatcacagctgcaaagatggcccaggatgtcgct accaatgtcaactacaaacagccattgcatcattacacatacctacctgacgccatgagt cttgagcatacgaggaatgtcaatcaaattcagagtgataatgtgtataaagacgagtat aacagcttcttgaagggcatcggatggatccctattggttccctggaggtggagaaggtc aagaaagcaggcgatgcattaaatgagaggaagtatcgacagcacccagataccgtcaag ttcacaagtgtgcctgattccatgggcatggtgttggctcagcataacacaaagcagcta agtgatttgaactacaaggtagagggagagaaactgaagcacaagtatactattgaccct gaattgcctcagtttattcaagccaaagtcaacgccctcaacatgagtgatgctcattat aaagcagattggaagaaaaccattgccaagggctatgatttgagaccagatgccatccca attgttgctgcaaaaagttcaaggaatattgctagtgattgcaaatataaggaggcctac gagaaagccaaaggcaagcaagttggatttctcagtcttcaggatgatcctaaactggtt cactacatgaatgtggccaaaatccagtctgatcgtgagtacaaaaagggctatgaagcc agcaagaccaagtaccacacacctctggatatggtcagtgtgacagctgcaaagaaatct caggaggttgccaccaacgccaactacagacagtcataccaccactacactctcctgccc gatgccttgaatgtggagcactccaggaatgccatgcagattcagagtgataatctgtac aaatctgacttcaccaattggatgaaagggatcggctgggtgcccatagagtccctggag gtggagaaggcaaagaaagcaggagagattcttagtgagaagaagtatcgccagcacccc gagaagctgaagttcacttacgccatggacacaatggaacaggcacttaacaagagtaac aaactgaacatggacaagaggctctacactgaaaaatggaacaaggacaagaccaccatt catgtcatgcctgacacaccggatattttactctccagagtaaaccaaatcaccatgagt gataaactgtacaaagctggctgggaagaggaaaagaagaaaggatatgacctgaggcct gatgccattgcaataaaggctgcaagagcctctagagacattgccagtgattacaaatac aagaaagcctatgaacaagccaaagggaaacacattggcttccggagcctggaagatgac cccaagctggtgcacttcatgcaagtggccaagatgcagtcagaccgggaatacaagaag ggatatgagaaatccaagacctccttccacaccccggtggacatgctcagtgtggtggca 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gacagggagtacaagaaggagtttgagaagtggaagaccaagttcagcagcccagtggac atgctgggggtggtgctggccaagaagtgtcagatccttgtaagcgacatagactacaag catcccctgcatgaatggacctgcctgcctgatcagaatgacgtcattcaggctcggaag gcctatgacctgcagagtgatgctatttacaaatctgatcttgagtggctgagaggcata ggatgggttcccattggctctgtagaggtcgagaaagtgaagagagctggagaaatcctg agtgacaggaagtatcgccagcctgcagaccagctcaaattcacatgcattaccgacact ccggaaattgtcctagcaaagaataatgccctgacaatgagcaagcatttatacacagaa gcttgggatgctgacaaaacctccatccacgtgatgccagacaccccagatatcctgctg gccaagagtaattctgccaatatcagccaaaaactttacaccaagggatgggatgaatca aagatgaaggactatgatctgagagcagatgctatttccatcaaaagtgccaaggcctcc agggacatcgccagtgactacaaatacaaggaagcctatgagaaacagaaaggccaccac attggagcccagagcattgaagatgatcccaagattatgtgtgccatacatgcaggaaaa attcaaagtgaaagggagtacaagaaggaattccaaaagtggaaaaccaagttctctagc ccagtggacatgttaagcatcttgctggccaagaaatgtcagactttggtcactgacatt gattatcgcaattacctgcatgaatggacatgcatgccggatcaaaacgacattatccaa gcaaaaaaggcctatgacctgcagagtgatagtgtgtataaggcagacctggagtggctg cgtggcatcggctggatgccagaaggctcagtggaaatgaacagagtgaaggttgctcaa gacctcgtgaatgaaagactctataggacacgtccagaagctttgtcattcaccagcatt gtcgacactccagaagttgtcttggcaaaagccaattctctgcaaataagtgagaaactg tatcaggaagcctggaataaagataaaagcaacatcaccattccttctgatactccggag atgctgcaggcccacatcaatgccttgcaaatcagcaataaactctaccaaaaagactgg aatgacgccaagcagaaaggctatgacataagggcagatgccattgaaatcaagcacgcc aaggcctccagagaaattgccagtgagtacaaatacaaagaaggttaccgtaagcaactg ggccaccacatgggtttccgcaccctacaagatgaccccaagtcagtatgggctatacat gctgccaagatccagagtgacagagaatataagaaagcttatgagaagtctaaaggaatt cacaacacaccgttggacatgatgtcaattgttcaagccaagaaatgccaggtcctggtt agcgacattgattatcgcaattatctgcaccagtggacgtgtctgccagatcagaacgat gtgatccaggccaagaaagcctacgacctgcagagcgataacttgtacaagtcagacctg gaatggctgaagggtattggatggctgccagagggttctgtggaagtgatgagagtgaag aatgcccagaatctcttgaatgaaaggctgtatcgtataaagcctgaggccctcaaattc accagcattgttgacaccccggaagtaatccaggcaaagatcaatgctgtacagatcagt gagccattgtatcgcgatgcctgggagaaagagaaggctaatgtgaacgtgccagctgac 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agcgacagtgtgtataaggcagacctggagtggctgcgtggcatcggctggatgccagaa ggctcagtggaaatgaacagagtgaaggttgctcaagacctcgtgaatgaaagactctat aggacacgtccagaagctttgtcattcaccagcattgtcgacactccagaagttgtcttg gcaaaagccaattctctgcaaataagtgagaaactgtatcaggaagcctggaataaagat aaaagcaacatcaccattccttctgatactccggagatgctgcaggcccacatcaatgcc ttgcaaatcagcaataaactctaccaaaaagactggaatgacaccaagcagaaaggctat gacataagggcagatgccattgaaatcaagcacgccaaggcctccagagaaattgccagt gagtacaaatacaaagaaggttaccgtaagcaactgggccaccacatgggtttccgcacc ctacaagatgaccccaagtcagtatgggctatacatgctgccaagatccagagtgacaga gaatataagaaagcttatgagaagtctaaaggaattcacaacacaccgttggacatgatg tcaattgttcaagccaagaaatgccaggtcctggttagcgacattgattatcgcaattat ctgcaccagtggacgtgtctgccagatcagaacgatgtgatccaggccaagaaagcctac gacctgcagagcgataacttgtacaagtcagacctggaatggctgaagggtattggatgg ttgccagagggttctgtggaagtgatgagagtgaagaatgcccagaatctcttgaatgaa aggctgtatcgtataaagcctgaggccctcaaattcaccagcattgttgacaccccggaa gtaatccaggcaaagatcaatgctgtacagatcagtgagccattgtatcgcgatgcctgg gagaaagagaaggctaatgtgaacgtgccagctgacactcccctgatgctgcaatccaaa atcaatgccctgcagatcagcaataaacgctatcagcaagcttgggaagatgtcaagatg actggttatgacctgcgagcagatgccattgggatccagcatgccaaggcttccagggat attgccagtgactatctgtacaaaactgcttatgagaaacagaaaggccattacattggc tgtcgcagcgccaaggaagaccctaaactggtttgggcagcaaatgtgttgaagatgcag aatgacaggctgtacaaaaaggcctacaacgaccacaaagccaagatctccatccctgtg gacatggtgtccatcagcgctgccaaagaaggtcaggcactggcaagtgatgtggactat cgccattacctgcaccgctggtcttgctttcccgaccagaatgatgtgatccaagccagg aaagcctacgacctacagagcgacgccctctacaaggctgacttggagtggttgcgtggc attggctggatgccccaagggtctcctgaagtgttgagagtcaaaaacgcccagaatatc ttttgtgacagtgtctatcggacgcctgtggtgaaccttaagtacacaagcattgttgac acacctgaagtggtccttgctaaatcaaatgctgaaaatattagtattccaaagtacaga gaggtttgggacaaggataaaacttcaatacacataatgccagatactccagaaattaat ctcgctagagcaaatgctcttaatgtgagcaataaactttaccgtgagggctgggatgaa atgaaggcgggctgtgatgtccggctggatgccatccccatccaggctgccaaggcctcc agggagattgccagtgactataaatataagcttgaccatgagaagcagaagggacactac 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attcaggcaagaaaggcctatgacctacagagtgataatgtctacagagctgacctggag tggctccgaggcattggctggatcccactggattctgtggaccatgtaagggttactaag aaccaggaaatgatgagtcagatcaaatataagaaaaatgcccttgaaaactatcctaac tttagaagtgtggtggatcctccagagattgttttagccaagattaattctgtcaatcaa agtgatgtaaaatataaagaaacatttaataaagcaaagggcaaatatacgttttcacca gatacaccacatatctcccactccaaagacatgggaaaactctacagtactatactgtat aaaggggcgtgggagggcaccaaggcctatggctacaccctggatgagcgctacattccc attgttggagccaagcatgctgatctggtgaacagtgagcttaaatacaaagagacatat gagaagcagaaaggtcactacctggctggaaaagtgatcggtgaattccctggtgtggtt cactgtctggatttccaaaagatgaggagtgcgttgaactacagaaaacattatgaggat accaaagcaaatgttcatatccccaatgacatgatgaatcacgtgctggctaaaaggtgc cagtacatcctcagtgacctggagtatcgacactatttccaccagtggacgtctcttctg gaagaacccaatgttatacgcgtccgaaacgcccaggagatcttgagtgataatgtgtat aaagatgacctgaattggttgaaaggcattggttgctacgtttgggatacaccccaaatc ctccatgccaagaaatcatacgaccttcagagtcagctacaatatacagcagcaggtaaa gaaaatctacaaaactataatctggtcacagacacgcccctctatgtgactgctgttcag agtggcattaatgccagtgaggtaaaatataaagaaaattatcatcagattaaggacaaa tacacaacagttctagaaacagtggattatgacagaaccagaaacctgaagaatctttac agcagtaacctgtacaaggaggcctgggatagagtgaaagccaccagctacatcctgcct tccagcaccttgtccctgacacacgccaagaaccagaagcatctggccagccatatcaaa tatcgggaagaatatgaaaagttcaaagctctttatacgttaccaagaagtgttgacgat gatccgaacacagcacggtgcctccgagttggcaagcttaacatcgatcgcctgtacaga tcagtttatgaaaagaacaagatgaaaatccacatcgtgcccgacatggtagagatggtt actgccaaggattcccagaagaaagtcagtgagattgattaccgcctgcgcctccacgaa tggatttgccaccccgacttgcaagtcaatgatcacgtcaggaaagtcacagatcagatc agcgatattgtatacaaggatgacctcaactggctgaaaggcattggttgctacgtctgg gacactcctgaaatcctccatgccaagcatgcttatgatctacgtgatgatatcaagtat aaagctcacatgttgaaaacaaggaatgactacaagcttgtcacagatacaccagtctac gtgcaggctgtcaaaagtgggaaacagctaagtgacgctgtctaccactatgactatgtg cacagtgtcagaggcaaagtggctccaactaccaaaaccgtggatctggaccgggccctt catgcatacaagctccagagttcgaatctatacaaaaccagcctgcgcaccctgcccact ggatatagacttccaggtgacactcctcacttcaaacacatcaaggacacccgttacatg agcagttatttcaagtacaaagaagcctatgaacacaccaaggcatatgggtatacactt ggccccaaagatgttccatttgtccacgtccggagagtcaacaatgttaccagcgagaga ctgtatcgggaattgtaccacaaactgaaagacaagatccatacaactcccgatacccct gagatccgccaagtcaagaagacacaagaggctgtcagtgagttgatctacaaatcagac ttcttcaagatgcagggccacatgatctctctgccatacacaccccaagtgatccattgc cgctatgtgggagacatcaccagtgatattaaatacaaagaggacttgcaggtcctgaag ggatttggctgcttcctgtatgacactcctgacatggtccgctcccggcacctgcggaag ctctggtctaattacctatacactgataaggcaaggaagatgcgagacaaatacaaagtg gtgcttgacactccagaatacagaaaagtgcaagaactgaagacacatctgagtgagctg gtctacagagctgcaggcaagaagcagaagtcaatctttacttcagttcctgatactcct gatcttttaagagccaagcgagggcagaagcttcagagtcagtatctgtatgttgaactt gccaccaaagagagaccccatcatcacgctggaaaccagaccacagccttgaagcatgct aaagacgtgaaggacatggtcagtgagaaaaagtacaagattcaatatgaaaagatgaaa gacaagtacactccggttccagatacgccaatcctcatcagagccaagagggcttactgg aatgccagtgatctacgctacaaagaaacatttcaaaagaccaaagggaaataccacacg gtgaaagatgccctagacattgtctatcatcgcaaagtcacagatgacatcagtaaaata aaatacaaggagaactacatgagccagttgggtatctggaggtccattcctgatcgtcca gagcatttccaccaccgagcagtcactgacacagtcagtgatgtaaaatataaagaagac ttgacttggcttaaaggcattggttgctatgcctatgatacccctgatttcactctggct gaaaagaacaagactctctacagcaagtataagtataaagaagtatttgaaaggacaaag tcagatttcaagtatgttgccgactctccgatcaataggcatttcaagtatgcaactcaa ttgatgaatgagaaaaaatacagagctgattatgagcagcggaaagataaataccacctg gtagtcgatgagcctagacatctgctggctaagaccgcaggcgaccagatcagtcagatc aaatacaggaaaaactatgaaaaatcaaaggacaaatttacctcaattgtggatactcca gaacacctgcgtactacaaaagtcaacaaacaaatcagcgatatcctttataaattggaa tacaacaaggccaaacccagaggctacaccacaatccacgacacacccatgttgctgcat gtccgcaaggttaaagatgaagtcagtgatctgaaatacaaagaagtataccaaagaaat aaatccaactgcaccattgagccagatgctgttcatatcaaagcagccaaggacgcctac aaagtcaacaccaatctggactataagaaacagtacgaagccaacaaagcccactggaag tggactcctgaccgaccggacttcctccaggctgccaagtcatccctgcagcaaagcgat tttgaatataagctggaccgggagttcctcaagggttgcaagctttctgtcactgatgac aaaaacacggtgctcgccctcaggaatactttaatagaaagtgatctgaaatacaaagag aaacatgtcaaggaaagaggaacctgccatgccgtacctgacacgcctcagatcctgctg gcgaagactgtcagcaacctggtgtctgagaacaagtacaaggaccatgtcaagaagcac ttggcacagggctcatacacaacactaccagagacccgggacactgttcacgtcaaggaa gtgaccaagcatgtcagtgatacaaattacaaaaagaagtttgtcaaggagaaaggaaaa tccaactactccatcatgctggagccaccagaggtgaaacatgctatggaagtggccaag aagcaaagtgatgtcgcttacagaaaagatgccaaagagaacctgcattacaccacagtg gctgatcgaccagacatcaagaaggccacacaggcagccaaacaggccagtgaggtggag tacagagccaagcaccgcaaggaaggcagccatggcttaagcatgctcggtcgcccagac atagaaatggccaagaaggcagccaagctgagcagccaggttaaataccgagaaaatttc gataaagaaaagggcaagacaccaaaatacaatccaaaagacagccagctctacaaagtc atgaaagatgctaataatcttgcaagtgaggttaaatacaaggctgacctgaagaaactt cacaaacccgtgactgacatgaaggagtctctgatcatgaatcatgtcctgaatacaagc caacttgccagttcttaccagtacaagaagaagtatgagaagagtaaaggccactaccac accatacccgataatctggagcagcttcacctaaaagaggccacagaattacagagtata gtgaaatacaaagaaaagtatgaaaaggaacgaggaaaacccatgctggactttgaaaca ccaacgtacatcactgccaaagagtctcagcagatgcagagtgggaaagaatataggaaa gattatgaagagtccattaaaggcagaaacctgactggcctggaggtcacgccagctttg ttacatgtcaaatatgcaactaaaatagcaagcgagaaagagtacaggaaagatctagag gaaagcatccgtgggaagggcctcactgaaatggaagatacacctgacatgctaagagca aagaatgccactcaaatcctcaatgagaaagaatataagcgagacctggaactggaagtc aaaggaagaggcctgaatgccatggccaatgaaactccggattttatgagggccaggaat gctactgatattgccagtcagattaagtataagcaatcagcagaaatggagaaagccaat ttcacttctgtggttgatactccagagatcattcatgcccaacaagtcaagaatctttca agccagaaaaagtacaaggaagatgctgagaagtccatgtcgtattatgagactgttttg gacaccccagagatacagagagtccgggagaaccaaaagaacttcagccttctccaatac cagtgtgaccttaaaaacagtaaaggaaaaattacagttgttcaagacacgccagaaata ctgcgtgtaaaagaaaatcagaagaatttcagctcggttttatataaagaggatgtctca ccaggaacggctatcggaaagacacctgagatgatgagagtgaaacaaacacaggaccac attagctcggtgaagtataaggaagcaataggacaaggaactccaatccctgacctgcct gaagtgaaacgtgtgaaggagacgcagaagcacattagctcggttatgtacaaagaaaac ttgggaacaggcattccaaccactgtgactccagagattgagagagtcaaacgcaatcaa gagaactttagctcggttttgtacaaagaaaatttggggaaaggaatcccaacacctatc actccagagatggagagagtcaaacgcaatcaagagaactttagctcgatattgtacaaa gagaacttgagcaaggggactcccctacctgtcactcctgagatggagcgagtcaaactc aatcaagaaaactttagctcggtgttgtataaagaaaacgttggaaaagggattccaatc cccatcactccagagatggagagagtcaaacacaatcaagaaaactttagttcggtgcta tacaaagaaaacctggggacaggaattccaatccccatcactcctgagatgcagagagtc aaacacaatcaagaaaaccttagctcggtgttatacaaagaaaacatgggcaagggaacc cctttacctgtcactcccgagatggaaagagtcaaacacaatcaagaaaatattagctcg gtgttatacaaagaaaacatgggcaagggaacccctctacctgtcactcctgagatggag agagtcaaacacaatcaagaaaatattagctcggtgttatacaaagaaaacatgggcaag ggaactcctttagctgtcactcccgagatggagcgagtcaaacacaatcaagaaaatatt agctcggttttgtacaaagaaaatgtggggaaagccaccgcaacccctgtcactcctgag atgcagagagtcaaacgcaatcaagaaaacattagctcggtgttatacaaagagaacctg gggaaagcaacccccacaccctttactcctgagatggaaagagtgaaacgcaatcaagaa aactttagctcggtattgtacaaagagaacatgagaaaagcaactccgacacctgttact ccagagatggagagagctaagcgcaaccaagaaaacattagctcggttctttattctgat agtttccggaaacaaatacaaggcaaagctgcctatgtattggatacccccgagatgaga cgggtgagggagacccaacggcacatctcaacggtgaaatatcatgaagactttgagaaa cacaagggttgcttcacaccagtggtgacagatcctatcactgaacgagtaaagaagaac atgcaggacttcagtgacattaactaccgaggtattcagaggaaagtggtagaaatggaa caaaaacggaatgaccaagatcaggagactattacaggtttacgtgtctggcgtactaat cctggttcggtttttgactatgatccagcagaagacaacatccagtcccgaagcttacac atgattaatgtccaagctcagcgccggagccgggagcagtcacgatctgccagtgcacta agcatcagtgggggtgaggagaagtctgagcattcagaagcaccagaccaccacctttcg acttacagcgacgggggtgtctttgcagtctcaacagcttacaaacatgcaaaaaccaca gagctcccacaacaacgatcatcttcagttgctacccaacagacaacggtatcttccatc ccatctcatccatctactgctggaaaaatcttccgtgccatgtatgactatatggctgct gatgcagatgaggtgtccttcaaggatggagatgccatcataaatgttcaagcaattgat gaaggctggatgtatggcactgtgcagaggactggcaggaccggaatgctcccagccaac tacgttgaagctatttag

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