VARIANT: 3293v1
Help
Entry
3293v1 Variant
Name
HSD17B3 deficiency
Type
Loss of function
Gene
HSD17B3
hydroxysteroid 17-beta dehydrogenase 3 [KO:
K10207
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
mutations
OmimVar:
605573
Network
nt06019
Steroid hormone biosynthesis
Disease
H00608
46,XY disorder of sex development due to testosterone secretion defect
Reference
PMID:
8075637
Authors
Geissler WM, Davis DL, Wu L, Bradshaw KD, Patel S, Mendonca BB, Elliston KO, Wilson JD, Russell DW, Andersson S
Title
Male pseudohermaphroditism caused by mutations of testicular 17 beta-hydroxysteroid dehydrogenase 3.
Journal
Nat Genet 7:34-9 (1994)
DOI:
10.1038/ng0594-34
LinkDB
All DBs
DBGET
integrated database retrieval system