VARIANT: 4193v1
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Entry
4193v1 Variant
Name
MDM2 amplification
Gene
MDM2
MDM2 proto-oncogene [KO:
K06643
]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
amplification
ClinVar:
268075
150740
dbVar:
nsv917029
Network
nt06230
Cell cycle (cancer)
nt06273
Glioma
Disease
H00042
Glioma
Reference
PMID:
16434325
Authors
Bello MJ, Rey JA
Title
The p53/Mdm2/p14ARF cell cycle control pathway genes may be inactivated by genetic and epigenetic mechanisms in gliomas.
Journal
Cancer Genet Cytogenet 164:172-3 (2006)
DOI:
10.1016/j.cancergencyto.2005.07.002
Reference
PMID:
16319692
Authors
Arjona D, Bello MJ, Alonso ME, Isla A, De Campos JM, Vaquero J, Sarasa JL, Gutierrez M, Rey JA
Title
Real-time quantitative PCR analysis of regions involved in gene amplification reveals gene overdose in low-grade astrocytic gliomas.
Journal
Diagn Mol Pathol 14:224-9 (2005)
DOI:
10.1097/01.pas.0000177799.58336.1a
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