KEGG   VARIANT: 4193v1
Entry
4193v1                      Variant                                
Name
MDM2 amplification
Gene
MDM2  MDM2 proto-oncogene [KO:K06643]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
amplification
ClinVar: 268075 150740
dbVar: nsv917029
Network
nt06230  Cell cycle (cancer)
nt06273  Glioma
Disease
H00042  Glioma
Reference
PMID:16434325
  Authors
Bello MJ, Rey JA
  Title
The p53/Mdm2/p14ARF cell cycle control pathway genes may be inactivated by genetic and epigenetic mechanisms in gliomas.
  Journal
Cancer Genet Cytogenet 164:172-3 (2006)
DOI:10.1016/j.cancergencyto.2005.07.002
Reference
PMID:16319692
  Authors
Arjona D, Bello MJ, Alonso ME, Isla A, De Campos JM, Vaquero J, Sarasa JL, Gutierrez M, Rey JA
  Title
Real-time quantitative PCR analysis of regions involved in gene amplification reveals gene overdose in low-grade astrocytic gliomas.
  Journal
Diagn Mol Pathol 14:224-9 (2005)
DOI:10.1097/01.pas.0000177799.58336.1a
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