KEGG   VARIANT: 4824v1
Entry
4824v1                      Variant                                
Name
NKX3-1 loss
Gene
NKX3-1  NK3 homeobox 1 [KO:K09348]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
Allelic loss on 8p
Network
nt06214  PI3K signaling (cancer)
nt06272  Prostate cancer
Disease
H00024  Prostate cancer
Reference
PMID:20588175
  Authors
Gurel B, Ali TZ, Montgomery EA, Begum S, Hicks J, Goggins M, Eberhart CG, Clark DP, Bieberich CJ, Epstein JI, De Marzo AM
  Title
NKX3.1 as a marker of prostatic origin in metastatic tumors.
  Journal
Am J Surg Pathol 34:1097-105 (2010)
DOI:10.1097/PAS.0b013e3181e6cbf3
Reference
PMID:16061659
  Authors
Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C
  Title
Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis.
  Journal
Cancer Res 65:6773-9 (2005)
DOI:10.1158/0008-5472.CAN-05-1948
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