KEGG ORTHOLOGY: K09348

ORTHOLOGY: K09348

Entry

K09348                      KO

Symbol

NKX3-1

Name

homeobox protein Nkx-3.1

Pathway

map05200

Pathways in cancer

map05215

Prostate cancer

Disease

H00024

Prostate cancer

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K09348  NKX3-1; homeobox protein Nkx-3.1
  09162 Cancer: specific types
   05215 Prostate cancer
    K09348  NKX3-1; homeobox protein Nkx-3.1
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors
    K09348  NKX3-1; homeobox protein Nkx-3.1
Transcription factors [BR:ko03000]
Eukaryotic type
  Helix-turn-helix
   Homeo domain ANTP: NKL
    K09348  NKX3-1; homeobox protein Nkx-3.1

Genes

HSA:	4824(NKX3-1)

PTR:	743612(NKX3-1)

PPS:	100967944(NKX3-1)

GGO:	101150004(NKX3-1)

PON:	100436271(NKX3-1)

PPYG:

129041945(NKX3-1)

NLE:	100605136(NKX3-1)

HMH:	116461941(NKX3-1)

SSYN:

129491411(NKX3-1)

MCC:	710591(NKX3-1)

MCF:	102142281(NKX3-1)

MTHB:

126960732

MNI:	105482055(NKX3-1)

CSAB:

103215487(NKX3-1)

CATY:

105579205(NKX3-1)

PANU:

101007449(NKX3-1)

TGE:	112630083(NKX3-1)

RRO:	104657287(NKX3-1)

RBB:	108537886(NKX3-1)

TFN:	117093523(NKX3-1)

PTEH:

111545709(NKX3-1)

CANG:

105526578(NKX3-1)

CJC:	100412294(NKX3-1)

SBQ:	101050593(NKX3-1)

CIMI:

108318581(NKX3-1)

ANAN:

105705446(NKX3-1)

MMUR:

105857172(NKX3-1)

LCAT:

123626349(NKX3-1)

PCOQ:

105825248(NKX3-1)

OGA:	100964897(NKX3-1)

MMU:	18095(Nkx3-1)

MCAL:

110309320(Nkx3-1)

MPAH:

110325998(Nkx3-1)

RNO:	305999(Nkx3-1)

MCOC:

116084616(Nkx3-1)

ANU:	117706349(Nkx3-1)

ASYL:

127690661(Nkx3-1)

MUN:	110554945(Nkx3-1)

CGE:	100752275(Nkx3-1)

MAUA:

101823636(Nkx3-1)

PROB:

127230225(Nkx3-1)

PLEU:

114702670(Nkx3-1)

MORG:

121455883(Nkx3-1)

MFOT:

126488403

AAMP:

119799737(Nkx3-1)

NGI:	103748169(Nkx3-1)

HGL:	101702066(Nkx3-1)

CPOC:

100730521(Nkx3-1)

CCAN:

109695389(Nkx3-1)

DORD:

105999400(Nkx3-1)

DSP:	122123529(Nkx3-1)

PLOP:

125339596(Nkx3-1)

NCAR:

124983244

MMMA:

107153831(Nkx3-1)

ITI:	101960786(Nkx3-1)

OCU:

100354093

OPI:	101521372(NKX3-1)

TUP:	102469057(NKX3-1)

GVR:	103592527(NKX3-1)

CFA:	486114(NKX3-1)

CLUD:

112669736(NKX3-1)

VVP:	112926744(NKX3-1)

VLG:	121497928(NKX3-1)

NPO:	129493819(NKX3-1)

AML:	105235627(NKX3-1)

UMR:	121101889(NKX3-1)

UAH:	113270069(NKX3-1)

UAR:	123777435(NKX3-1)

ELK:

111156657

LLV:

125092878

MPUF:

101691082(NKX3-1)

MNP:	132013390(NKX3-1)

MLK:	131833980(NKX3-1)

NVS:	122919221(NKX3-1)

ORO:	101364398(NKX3-1)

EJU:	114217508(NKX3-1)

ZCA:	113924751(NKX3-1)

MLX:	118022373(NKX3-1)

NSU:	110588605(NKX3-1)

LWW:	102740342(NKX3-1)

FCA:	105260486(NKX3-1)

PYU:	121039851(NKX3-1)

PCOO:

112869841(NKX3-1)

PBG:	122472180(NKX3-1)

PVIV:

125164941(NKX3-1)

LRUF:

124520457

LGF:	123587310(NKX3-1)

AJU:

106966563

PTG:	102950628(NKX3-1)

PPAD:

109277326

PUC:

125923350

PLEZ:

122217513(NKX3-1)

HHV:	120239483(NKX3-1)

BTA:	782252(NKX3-1)

BOM:	102276569(NKX3-1)

BIU:	109563136(NKX3-1)

BBUB:

102396019(NKX3-1)

BBIS:

104994593(NKX3-1)

CHX:	102181392(NKX3-1)

OAS:	101113199(NKX3-1)

BTAX:

128052801(NKX3-1)

CSUM:

138080634(NKX3-1)

ODA:	120865795(NKX3-1)

CCAD:

122431857(NKX3-1)

MREE:

136176626(NKX3-1)

OVR:	110133926(NKX3-1)

SSC:	100738625(NKX3-1)

CFR:	116660739(NKX3-1)

CBAI:

105069033(NKX3-1)

CDK:	116149897(NKX3-1)

VPC:	102539411(NKX3-1)

BACU:

103000404(NKX3-1)

BMUS:

118897072(NKX3-1)

LVE:	103091490(NKX3-1)

OOR:	101275595(NKX3-1)

LALB:

132523019(NKX3-1)

DLE:	111185331(NKX3-1)

PCAD:

102985475(NKX3-1)

PSIU:

116755619(NKX3-1)

NASI:

112401453(NKX3-1)

ECB:	100058172(NKX3-1)

EPZ:	103550759(NKX3-1)

EAI:	106843675(NKX3-1)

MYB:	102261950(NKX3-1)

MYD:	102769922(NKX3-1)

MMYO:

118657560(NKX3-1)

MLF:	102435750(NKX3-1)

MDT:	132234711(NKX3-1)

MYUM:

139009967(NKX3-1)

PKL:	118726038(NKX3-1)

EFUS:

103295060(NKX3-1)

MNA:	107536081(NKX3-1)

DRO:	112305233(NKX3-1)

SHON:

118975140(NKX3-1)

AJM:	119054773(NKX3-1)

PDIC:

114503322(NKX3-1)

PHAS:

123828171(NKX3-1)

MMF:	118616283(NKX3-1)

PPAM:

129074892(NKX3-1)

HAI:	109372326(NKX3-1)

RFQ:	117037465(NKX3-1)

PALE:

102880253(NKX3-1)

PGIG:

120606453(NKX3-1)

PVP:	105304705(NKX3-1)

RAY:	107509199(NKX3-1)

MJV:	118973595(NKX3-1)

TOD:	119233467(NKX3-1)

SARA:

101538807(NKX3-1)

SFUM:

130028091(NKX3-1)

SETR:

126003325(NKX3-1)

LAV:	100662288(NKX3-1)

TMU:

101341593

ETF:	101657224(NKX3-1)

DNM:	101439001(NKX3-1)

MDO:	100020925(NKX3-1)

GAS:	123234482(NKX3-1)

SHR:	100913737(NKX3-1)

AFZ:

127547346

PCW:	110218449(NKX3-1)

TVP:	118844286(NKX3-1)

PBRV:

138145228(NKX3-1)

OAA:	100075889(NKX2-6) 103169517(NKX3-1)

TACU:

119928829(NKX3-1)

GGA:	101747314(NKX3-1)

PCOC:

116238367(NKX3-1)

MGP:	104914216(NKX3-1)

CJO:	107323681(NKX3-1)

TPAI:

128090057(NKX3-1)

LMUT:

125685323(NKX3-1)

NMEL:

110387143(NKX3-1)

APLA:

119713552(NKX3-1)

ACYG:

125179726(NKX3-1)

CATA:

118256028(NKX3-1)

AFUL:

116499491(NKX3-1)

TGU:	115498082(NKX3-1)

SCAN:

115484422(NKX3-1)

PMOA:

120497180(NKX3-1)

OTC:	121346811(NKX3-1)

PRUF:

121366012(NKX3-1)

ATRC:

139603800(NKX3-1)

GFR:	102044871(NKX3-1)

FAB:	101814905(NKX3-1)

OMA:	130261934(NKX3-1)

PHI:	102102215(NKX3-1)

PMAJ:

107213802(NKX3-1)

CCAE:

111938810(NKX3-1)

CCW:	104694831(NKX3-1)

CBRC:

103614880(NKX3-1)

ACOE:

138121695(NKX3-1)

ETL:	114068767(NKX3-1)

ZLE:	135456845(NKX3-1)

ACHL:

103806560

MMEA:

130586855

HRT:	120764048(NKX3-1)

SATI:

136372483(NKX3-1)

CCIC:

134054773(NKX3-1)

FPG:	101918618(NKX3-1)

FCH:	102053866(NKX3-1)

CCRI:

104158699(NKX3-1)

NNT:

104407961

SHAB:

115618564(NKX3-1)

ACUN:

113488119(NKX3-1)

TALA:

104364814(NKX3-1)

ACHC:

115350002(NKX3-1)

HALD:

104316256

HLE:	104828846(NKX3-1)

AGEN:

126051787

HHAR:

128150098(NKX3-1)

GCL:

127025269

CSTI:

104554082(NKX3-1)

DPUB:

104297818(NKX3-1)

PPUS:

135192433(NKX3-1)

AVIT:

104276725

EGZ:	104123539(NKX3-1)

NNI:	104019536(NKX3-1)

PCAO:

104050900

PADL:

103913106(NKX3-1)

AFOR:

103893821(NKX3-1)

FGA:

104078848

GSTE:

104258803

CBOY:

140643987(NKX3-1)

CLV:	110355415(NKX3-1)

MUI:	104547275(NKX3-1)

PGUU:

104463919

PLET:

104626651

EHS:	104510522(NKX3-1)

CMAC:

104485215(NKX3-1)

CUCA:

104068603(NKX3-1)

BREG:

104642211(NKX3-1)

ACAR:

104531847(NKX3-1)

CPEA:

104397218(NKX3-1)

CVF:	104285671(NKX3-1)

RTD:	128900099(NKX3-1)

CRID:

134526674(NKX3-1)

AROW:

112973624(NKX3-1)

NPD:	112950193(NKX3-1)

ASN:	102383716(NKX3-1)

AMJ:	102563056(NKX3-1)

PSS:	102443627(NKX3-1)

CMY:	102931933(NKX3-1)

CCAY:

125626324(NKX3-1)

DCC:	119848756(NKX3-1)

CPIC:

101948638(NKX3-1)

TST:	117872952(NKX3-1)

CABI:

116826019(NKX3-1)

MRV:	120397600(NKX3-1)

ACS:	100563371(nkx3-1)

ASAO:

132782506(NKX3-1)

PVT:	110072236(NKX3-1)

SUND:

121935058(NKX3-1)

PBI:	103058450(NKX3-1)

PMUR:

107293146(NKX3-1)

CTIG:

120312900(NKX3-1)

TSR:	106541391(NKX3-1)

PGUT:

117676952 132712358(NKX3-1)

APRI:

131203870(NKX3-1)

PTEX:

113445641 113445687

NSS:	113420977(NKX3-1)

VKO:	123027035(NKX3-1)

PMUA:

114585526(NKX3-1)

PRAF:

128403179(NKX3-1)

ZVI:	118096800(NKX3-1)

HCG:	128333501(NKX3-1)

STOW:

125442067(NKX3-1)

EMC:	129341815(NKX3-1)

XLA:	373737(nkx3-1.S) 379899(nkx3-1.L)

XTR:	100038192(nkx3-1)

NPR:	108799268(NKX3-1)

RTEM:

120933085(NKX3-1)

BBUF:

120986154(NKX3-1)

BGAR:

122925655(NKX3-1)

PWL:	138265934(NKX3-1)

MUO:	115468090(NKX3-1)

GSH:	117362040(NKX3-1)

DRE:	555375(nkx3-1)

SRX:	107710828 107757886

SANH:

107665190 107678393

SGH:

107559446

CCAR:

109088774 109112448

CAUA:

113040653 113106759(nkx3-1)

CGIB:

127962844 128019204

PTET:

122350117(nkx3-1)

LROH:

127170057(nkx3-1)

OMC:	131545856(nkx3-1)

PPRM:

120481354(nkx3-1)

RKG:	130081830(nkx3-1)

MAMB:

125279853(nkx3-1)

CIDE:

127517518

CERY:

137026657(nkx3-1)

MASI:

127415490 127423982

TROS:

130568438(nkx3-1)

TDW:	130407022(nkx3-1)

MANU:

129413768(nkx3-1)

PDAB:

135730121(nkx3-1)

IPU:

108266005

IFU:	128607227(nkx3-1)

PHYP:

113533251(nkx3-1)

SMEO:

124400170(nkx3-1)

TFD:	113646485(nkx3-1)

TVC:	132853595(nkx3-1)

CGAR:

128530595(nkx3-1)

NGRA:

132892424(nkx3-1)

TRN:	134317481(nkx3-1)

AMEX:

103038181(nkx3-1)

CMAO:

118812889(nkx3-1)

EEE:

113578175

CHAR:

122130946(nkx3-1)

SPIL:

134088562(nkx3-1)

TFS:	130525940(nkx3-1)

TNG:	GSTEN00020437G001

LCO:

104934620

TBEN:

117496838(nkx3-1)

CGOB:

115013841(nkx3-1)

PGEO:

117453102(nkx3-1)

GACU:

117561126(nkx3-1)

EMAC:

134873094(nkx3-1)

ELY:	117253145(nkx3-1)

EFO:	125890325(nkx3-1)

PLEP:

121945049(nkx3-1)

SLUC:

116053918(nkx3-1)

ECRA:

117945059(nkx3-1)

ESP:

116690217

PFLV:

114556298

GAT:	120830112(nkx3-1)

PPUG:

119224603(nkx3-1)

AFB:	129101758(nkx3-1)

CLUM:

117736527(nkx3-1)

PSWI:

130196175(nkx3-1)

CANA:

137779201(nkx3-1) 137793381

CVE:	137867460(nkx3-1)

MSAM:

119891176(nkx3-1)

SCHU:

122876978(nkx3-1)

CUD:	121510463(nkx3-1)

SPUL:

138610925(nkx3-1)

LMIX:

132974975(nkx3-1)

ALAT:

119019783(nkx3-1)

ASTR:

137593070(nkx3-1)

MZE:

101473587

ONL:

100692555

OAU:	116310248(nkx3-1)

OLA:

101167461

OML:	112148633(nkx3-1)

CSAI:

133451020(nkx3-1)

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122827994(nkx3-1)

PPRL:

129372191(nkx3-1)

CVG:

107093866

CTUL:

119783977(nkx3-1)

GMU:	124878472(nkx3-1)

NFU:

107393769

KMR:	108236589(nkx3-1)

ALIM:

106520416

NWH:	119413464(nkx3-1)

AOCE:

111578666(nkx3-1)

EJA:	138191599(nkx3-1)

BFRE:

138621527(nkx3-1)

MCEP:

125012422(nkx3-1)

CSEM:

103398266(nkx3-1)

POV:

109633693

SSEN:

122769099(nkx3-1)

SSOE:

131464294(nkx3-1)

HHIP:

117768456(nkx3-1)

HSP:	118115330(nkx3-1)

PPLT:

128438212(nkx3-1)

SMAU:

118314556(nkx3-1)

LCF:

108878096

SDU:

111230725

SLAL:

111663963

XGL:	120805680(nkx3-1)

HCQ:

109525219

SSCV:

125994374(nkx3-1)

SBIA:

133499555(nkx3-1)

PEE:	133400031(nkx3-1)

PTAO:

133475865(nkx3-1)

BPEC:

110169949

ENY:	140346927(nkx3-1)

MALB:

109956869(nkx3-1)

BSPL:

114862455(nkx3-1)

SJO:	128365151(nkx3-1)

SSCO:

133979613(nkx3-1)

GMH:	115545693(nkx3-1)

SASA:

100196037(nkx3-1) 100196040(nkx31)

STRU:

115164547 115200099

OTW:	112249684 112263994(nkx3-1)

OMY:	110525021 110536005(nkx3-1)

OGO:	124033317 124035209

ONE:	115111034 115140574(nkx3-1)

OKI:	109871954 109895113

OKE:	118357928 118394228

OMM:	135513540(nkx3-1) 135550749

OCLA:

139390029 139412012

SALP:

111957894 111974709

SNH:	120054647 120062740

CCLU:

121584167 121587343

ELS:	105014031(nkx3-1)

OEP:	134011941(nkx3-1)

SFM:	108929504(nkx3-1)

PKI:	111857510(nkx3-1)

AANG:

118237255(nkx3-1)

AROT:

135261273(nkx3-1)

CCOG:

133141196(nkx3-1)

LOC:	102692325(nkx3-1)

PSPA:

121302464 121303206

ARUT:

117397975(nkx3-1) 117971681

PSEX:

120539808(nkx3-1)

LCM:	102364860(NKX3-1)

RTP:

109911592

CPLA:

122543045(nkx3-1)

HOC:

LERI:

BBEL:

TPAL:

HRF:

HCRA:

MCAZ:

MFOO:

137983890 137983891 137984530

RES:

135687431

» show all

Reference

PMID:12036903

Authors

Kim MJ, Bhatia-Gaur R, Banach-Petrosky WA, Desai N, Wang Y, Hayward SW, Cunha GR, Cardiff RD, Shen MM, Abate-Shen C

Title

Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis.

Journal

Cancer Res 62:2999-3004 (2002)

Sequence

[mmu:18095]

LinkDB

DBGET integrated database retrieval system