KEGG   VARIANT: 999v1
Entry
999v1                      Variant                                 
Name
CDH1 reduced expression
Gene
CDH1  cadherin 1 [KO:K05689]
Organism
hsa_var Human gene variants (Homo sapiens)
Variation
reduced expression
Network
nt06215  WNT signaling
nt06274  Thyroid cancer
  Element
N00061  CDH1-reduced expression to beta-catenin signaling pathway
Reference
  Authors
Kato N, Tsuchiya T, Tamura G, Motoyama T
  Title
E-cadherin expression in follicular carcinoma of the thyroid.
  Journal
Pathol Int 52:13-8 (2002)
DOI:10.1046/j.1440-1827.2002.01310.x
Reference
  Authors
Rocha AS, Soares P, Fonseca E, Cameselle-Teijeiro J, Oliveira MC, Sobrinho-Simoes M
  Title
E-cadherin loss rather than beta-catenin alterations is a common feature of poorly differentiated thyroid carcinomas.
  Journal
Histopathology 42:580-7 (2003)
DOI:10.1046/j.1365-2559.2003.01642.x
Reference
  Authors
Rocha AS, Soares P, Seruca R, Maximo V, Matias-Guiu X, Cameselle-Teijeiro J, Sobrinho-Simoes M
  Title
Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant.
  Journal
J Pathol 194:358-66 (2001)
DOI:10.1002/path.905
Reference
PMID:8985087
  Authors
Soares P, Berx G, van Roy F, Sobrinho-Simoes M
  Title
E-cadherin gene alterations are rare events in thyroid tumors.
  Journal
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