Hippoglossus stenolepis (Pacific halibut): 118119640
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Entry
118119640 CDS
T08308
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
hsp
Hippoglossus stenolepis (Pacific halibut)
Pathway
hsp00140
Steroid hormone biosynthesis
hsp01100
Metabolic pathways
Module
hsp_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
hsp_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
hsp_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
hsp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
118119640
Enzymes [BR:
hsp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
118119640
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
118119640
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Motif
Pfam:
3Beta_HSD
Epimerase
GDP_Man_Dehyd
NAD_binding_4
Polysacc_synt_2
NAD_binding_10
RmlD_sub_bind
KR
adh_short
NmrA
Motif
Other DBs
NCBI-GeneID:
118119640
NCBI-ProteinID:
XP_035029643
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Position
13:complement(21269962..21273150)
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AA seq
374 aa
AA seq
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MSLGGDVCVVTGACGFLGRRLVKLLLEEETMAEIRMLDKHVQPQVLQTLEDCRGSTQLSV
FEGDIRDSDFVRKACRGASVIFHTASIIDVNGSVEYSEMYGVNVKGTQVLLEACVQENVV
SLIYTSSIEVMGPNPKGEPIINGSEDTIYDSTLRFSYSKTKNEAEQRTLLAHGEVLQNGG
RLATCALRPMYIFGEGCRFLLGHMDDGIRNEDVLLRMSLPEARVNPVYVGNVAAAHLQAA
RGLKDPQKRNVIGGKFFFISDDTPPVSYSDFNHVLMAPLGFNIQEKLRLPLYLLYALCFI
LEILCTMIRPLIRVALPLNRQLLTMLNTPFTFSYQKAKRDLGYEPKYSWEEARKHTIEWL
ASELPKERERITAK
NT seq
1125 nt
NT seq
+upstream
nt +downstream
nt
atgtctctgggaggtgatgtgtgtgtggtgacgggagcctgtggattcctgggaaggagg
ctggtgaagctgctgctggaggaagagacgatggcggagattcggatgttggacaaacac
gtacaacctcaagttttacagactctggaggattgtagaggcagcacacagctgagtgtg
ttcgagggagacatcagggacagtgattttgtgaggaaagcctgtcgaggtgcgtcagtc
atcttccacacggcctccatcatcgacgtcaatggatcagtggagtacagtgaaatgtat
ggggtcaatgtcaaaggaacgcaggttcttctggaggcctgtgttcaggagaacgtggtg
tccttaatctacaccagctccatcgaggtgatgggaccaaaccccaaaggtgaacccata
atcaacggcagcgaggacacaatttatgacagtaccttgaggttttcctacagcaagacc
aaaaatgaggcagagcagagaaccctgctggcccacggagaggtgcttcagaacggaggc
cgactggccacctgtgccctcagacctatgtacatctttggcgaagggtgtcgcttcctg
ctgggccacatggacgacgggatacgaaacgaggacgttctgttgagaatgtctctacca
gaggctcgagtgaatcctgtctacgtgggaaacgtagccgcggctcatctccaagcagct
cgcggcctcaaagatccacaaaagagaaatgtgataggaggaaagtttttctttatttct
gatgacacgccgccggtgagctactcagacttcaaccacgtcctgatggcgcctctgggc
ttcaacattcaagagaaactccggctgccgctctacctcctctacgcgctctgtttcatt
ttggagatcctgtgcacgatgatccgacctctcatacgtgtcgccctgccgctgaaccgg
cagctcctcaccatgttgaacacgccgttcaccttctcctatcagaaagccaagagggat
ctaggatacgagcccaagtacagctgggaggaagcacgcaaacacaccattgaatggctc
gcctcagagctgcctaaagagagggaacgaattacagctaaatga
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