Hydrogenophilus thermoluteolus: HPTL_1127
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Entry
HPTL_1127 CDS
T05630
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
htl
Hydrogenophilus thermoluteolus
Pathway
htl00010
Glycolysis / Gluconeogenesis
htl00020
Citrate cycle (TCA cycle)
htl00620
Pyruvate metabolism
htl00785
Lipoic acid metabolism
htl01100
Metabolic pathways
htl01110
Biosynthesis of secondary metabolites
htl01120
Microbial metabolism in diverse environments
htl01200
Carbon metabolism
htl01210
2-Oxocarboxylic acid metabolism
Module
htl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
htl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
HPTL_1127 (pdhA)
00020 Citrate cycle (TCA cycle)
HPTL_1127 (pdhA)
00620 Pyruvate metabolism
HPTL_1127 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
HPTL_1127 (pdhA)
Enzymes [BR:
htl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
HPTL_1127 (pdhA)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
DUF3135
PriCT_1
Motif
Other DBs
NCBI-ProteinID:
BBD77391
UniProt:
A0A2Z6DY22
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All DBs
Position
1200465..1203161
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AA seq
898 aa
AA seq
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MAERHRQIILQNDPDPEETQEWLEALDGVIEHEGPERAHYLIESLISEAREHGADIPYSA
NTAYVNTIPADKQPPYPGDPDLEIKIHSYIRWNAMAMVVRANRDSNVGGHIASFASAAVL
YDVGFNHFFHAPTEDHGGDLVYFQGHSAPGIYARAFLLGRLTEEQMINFRREVDGKGLSS
YPHPWLMPQFWQFPTVSMGLGPIQAIYQARFIKYLITRGLVDPAKHEQRKVWCFIGDGET
DEVETLGAIGMAAREKLDNLIFVINCNLQRLDGPVRGNGKIIQELEAEFRGAGWNVIKVI
WGTHWDALFARDKTGALRRRMMELCDGDYQTFKAKDGAYVREHFFNTPELKALVADWTDE
EIWQLNRGGHDIFKVFAAYKAAVEHKGQPTVILAKTIKGYGMGQAGEAMNIAHQAKKMDH
DAIRRFRDRFQLPVPDDKLDELPFLTFAPDSAEYRYMQERRQALGGYLPQRRTKSEITLP
VPPLDAFKSFFAGTGPGREISTTMALVRIMIQLMRDKQLGKHIVPIVPDESRTFGMEGMF
RQFGIWSQEGQKYVPEDHDQLMFYKESRDGQILQEGINEAGAVCDFIAAGTSYSVHGVPM
IPFYIFYSMFGFQRTMDLIWAAADQRTRGFLIGGTSGRTTLNGEGLQHEDGHSHLLSAAV
PNCVSYDPTFQYEVAVIVQEGLRRMVAEQEDVFYYITVLNENYEHPPMPESETVREDILK
GMYLFQAAPDNLDGPRVQLMGSGAILREAIAAAELLARDWNVAADVWSCPSFTELARDGH
DCVRWNLLHPLEAPRKSHVEQKLENHPGPVVAATDYVRLFAEQIRPFVKRTYLTLGTDGF
GRSDTREKLRHFFEVDRHWITIAALKALADDGEIDRKLVAAALVKYGIDPEKPNPRLV
NT seq
2697 nt
NT seq
+upstream
nt +downstream
nt
atggctgaacgtcatcgtcaaatcattctgcaaaacgatcccgatcctgaagagacccaa
gaatggttggaagcgctcgatggcgtgatcgagcacgaagggccggagcgcgcgcactat
ctgatcgaatcgctgatcagtgaagcgcgcgaacacggtgccgacatcccctattccgcc
aatacggcatacgtcaacacgatccctgccgataaacaacccccgtacccgggtgacccg
gatctcgaaatcaaaatccattcctacatccgatggaatgcgatggcgatggttgttcgc
gccaatcgcgacagcaacgtgggtggccacatcgcctcgtttgcttcggcagcggtgctc
tacgacgttggcttcaaccacttcttccacgcgccaaccgaagaccacggcggcgacctc
gtctacttccaagggcactcggccccgggaatctatgcacgtgcttttctgcttgggcga
ttgaccgaagagcagatgatcaacttccggcgcgaagtcgacgggaaagggctctcttcc
tatccgcacccctggctgatgcctcagttctggcagtttcccacggtttcgatggggctg
ggcccgatccaagccatctaccaagcccgtttcatcaaatatctgatcacccgtggcctg
gtcgatccggcaaaacacgaacagcgcaaagtgtggtgcttcatcggggatggggaaacc
gacgaagtcgaaacccttggcgcgatcggaatggcagcacgggaaaagctcgacaacctg
attttcgtgatcaattgcaatttgcaacggctcgacgggccggtgcgcggcaacggaaag
atcatccaggagctcgaagcggaattccggggtgcgggttggaacgtgatcaaagtgatc
tggggtacccattgggacgcgctctttgctcgcgacaaaaccggtgccctccgacggcgg
atgatggagctctgcgacggggactaccagacgttcaaagcgaaagacggtgcgtacgtc
cgggagcacttcttcaatacccccgaactgaaagcgctcgttgccgactggaccgacgaa
gagatctggcagctcaaccgcggcggtcatgacattttcaaagtctttgccgcgtacaaa
gctgcggtcgaacataaagggcaacccaccgtgatccttgcgaagacaatcaaaggatac
ggaatgggacaagcgggcgaagcgatgaacatcgcccaccaggcaaagaagatggatcac
gacgcgatccgccgcttccgcgatcgtttccaactgcctgtgcccgacgacaaactcgat
gaactgccgttcctgacctttgcacccgactcggctgaataccgctacatgcaggagcgg
cggcaagcgcttgggggctatctcccgcagcgtcgaacgaaatccgaaatcaccttgccg
gttcccccgctcgatgcattcaaaagtttctttgccggaacgggaccggggcgggaaatc
tccacgacgatggcactcgtgcgcatcatgatccaactgatgcgcgacaaacagctcggc
aaacacattgtccccatcgtacccgacgaatcgcggacgttcgggatggaagggatgttc
cgtcagttcgggatctggagccaagaggggcaaaaatacgttcccgaagaccacgaccag
ttgatgttctacaaagagtcacgcgacggccaaatccttcaagaagggatcaacgaagcg
ggagccgtctgcgacttcatcgccgctggaacgagctacagcgtccatggcgtgccgatg
atcccgttctacatcttctattcgatgttcggcttccagcgcaccatggacctcatttgg
gccgcagcggatcagcgcacccgcgggttcctgatcggcggcacctcgggtcgaaccacg
ttgaacggtgaagggctgcagcacgaagacggccacagccatctgctctctgccgctgtc
cccaattgtgtaagctacgaccccaccttccaatacgaagtcgccgtgatcgttcaagaa
gggttgcggcgcatggtcgcagaacaagaggatgttttctattacatcacggtgctcaac
gaaaactacgaacatccgccgatgccggaaagcgagacggtccgtgaggatatcctcaaa
gggatgtatctcttccaggccgcgccggacaacctcgacggtccgcgtgtccagctcatg
gggtcgggggcgatcctacgcgaagcgatcgctgccgcagagttgctcgcgcgtgactgg
aacgtagccgcagacgtctggagctgcccaagtttcaccgaattggcgcgcgatggccac
gactgtgtccgctggaacctcctccacccgttggaagcgccccgcaagtcccacgtcgag
cagaagctcgagaaccatccggggccggtcgtagcggcaaccgactacgtccgtctcttt
gccgaacagattcggcctttcgtcaaacgaacgtatctcacactgggtaccgacgggttt
gggcgttccgatacccgcgagaagttgcgccacttcttcgaagtggatcgacactggatc
acgatcgccgcattgaaagcgcttgccgacgatggggagatcgatcgcaagctggttgcc
gcagcactcgtcaaatacggcatcgatcctgaaaaacccaacccccgcctggtgtaa
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