KEGG   Hydrogenovibrio thermophilus: EPV75_01190
Entry
EPV75_01190       CDS       T05808                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
htr  Hydrogenovibrio thermophilus
Pathway
htr00270  Cysteine and methionine metabolism
htr00450  Selenocompound metabolism
htr00670  One carbon pool by folate
htr01100  Metabolic pathways
htr01110  Biosynthesis of secondary metabolites
htr01230  Biosynthesis of amino acids
htr04981  Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:htr00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    EPV75_01190
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    EPV75_01190
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EPV75_01190
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    EPV75_01190
   04980 Cobalamin transport and metabolism
    EPV75_01190
Enzymes [BR:htr01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     EPV75_01190
SSDB
Motif
Pfam: Met_synt_B12 S-methyl_trans Pterin_bind B12-binding_2 B12-binding
Other DBs
NCBI-ProteinID: QAB14383
UniProt: A0A451G4I3
LinkDB
Position
complement(269317..273027)
AA seq 1236 aa
MTDRATRISQLKSLLAERIVILDGAMGTMVQSLQLSEDDFRGERFADYHMDIKGNNDILA
MTQPHLIRDIHLSFLNRGVDIVETNSFNATTIAQADYDMQDIVTELNIAAAQVAREACDL
AEQKDGQPRFVAGVLGPTNRTASISPDVNDPGKRNTDFDELVTAYTQATHGLLEGGADVI
LIETIFDTLNAKAAIFAVKEVEAAVGYEVPIMLSGTITDASGRTLSGQTTEAFYNAVAHA
QPLSVGLNCALGPEELRPYVAELSRVCETYVSVHPNAGLPNEFGEYDETPEQMAAEIAVW
AEKGWINIIGGCCGTTPDHVKAMADVALRHATRALPEIAPACRLSGLEPLNIDEDSLFVN
VGERNNVTGSAKFKRLIIEENYGEAIDIAVKQVEDGAQIIDVNMDEGMLDAKACMVKFLN
LLASEPEASRVPIMIDSSKWEVIEAGLKCIQGKGVVNSISLKEGEDAFIRQAKLVKQYGA
AAIVMAFDETGQADTLERKIEICKRSYEVLTQKVGFPPQDIIFDPNIFAVATGIEEHNNY
GLDFINAVTWIKANLPHAKISGGVSNVSFSFRGNNPVREAIHSVFLYYAIKEGMDMGIVN
AGQMAIYDDLPEKLRQAVEDVILNKDPEAGERLLEVAEEFRGDGQAASKVADTAWREQSV
EKRLEHALVKGITDYIEADTEEAYQKLGSGLHVIEGPLMDGMNVVGDLFGSGKMFLPQVV
KSARVMKRAVAYLDPYLLAAKTEGQQQGKIVMATVKGDVHDIGKNIVGVVLQCNNFEVID
LGVMVPAEKILDTAVEQGANVIGLSGLITPSLEEMVNVAKLMKERGMDLPLLIGGATTSK
AHTAVKIEPQYDHPVVYVKDASRAVGVAQSLISNDLKVDFAAKIRAEYEQVREERKARAQ
QVKRIPIKQARTNPALTDQAWQEFTPVRPKFLGTKVLDNFPLEKLVERFDWSPFFQAWEL
HGKYPRILDDKVVGEEARKVFADAQTMLKQIIDEKWLTAKAVYGFYPANRVGDDIEVYAD
ESRNQVLYTFHHLRQQAEKKRGGANNCLSDFIASKESRVPDYIGFFAVTAGIGIDEHVER
FEKDHDDYHAIMLKALADRFAEAFAETLHEIVRKDDWGYAPDENLDNEDLIKERYQGIRP
AAGYPACPDHTEKGTLWELLKPDETIGLDITESFAMTPTAAVSGTYFAHPESRYFGVGSL
GRDQVEDYAHRKGWSIEETEKWLAPNLGYDPEDFAN
NT seq 3711 nt   +upstreamnt  +downstreamnt
atgacggatcgcgcaactcggatttcacaactcaaatcgcttttggcggaacgcattgtc
atcctcgacggtgccatggggacaatggtgcaatccttgcagctcagtgaagacgacttc
cgtggcgaacgttttgccgattaccacatggacatcaaaggcaacaacgacattctggcc
atgacccagccgcacctgattcgtgacatccacttgtcgttcctcaatcgcggcgtcgat
atcgtcgaaaccaattccttcaacgccaccaccatcgcgcaggccgattacgacatgcag
gacatcgtcaccgagctgaacatcgccgccgcgcaagtggcgcgcgaagcctgcgacctg
gccgaacagaaagacggccagccgcgttttgtcgccggtgtcttggggccaaccaaccgc
actgcttcgatctcgccggacgtcaacgaccccggcaaacgcaacaccgatttcgacgaa
ctggtcaccgcttacacacaagccacgcacggcctgttggaaggcggcgcggacgttatt
ctgattgaaaccattttcgataccttgaacgccaaggccgccattttcgcggtgaaagaa
gtggaagccgctgtcggttacgaagtgccgattatgctgtccggcaccatcaccgatgct
tcaggccgaaccctttccggccagacgaccgaagccttctataacgccgttgctcacgca
caaccgctgtcggtcggcttgaactgcgccttggggccggaagagctgcgcccttacgtg
gccgaactcagccgcgtgtgcgagacctacgtgtccgttcaccccaacgccggtctgccg
aacgaattcggcgaatacgacgaaaccccggaacaaatggcggcggaaatcgccgtctgg
gcggaaaaaggttggattaatatcatcggcggttgctgcggcaccacgccggaccacgtc
aaagccatggccgatgtcgccttgcgccacgccacccgcgccttgccggaaatcgccccg
gcctgccgtttgtccggcctggaaccgctgaacatcgacgaagactctctgttcgtcaat
gtcggcgaacgtaacaacgtcaccggttccgccaaattcaaacgcctgattatcgaagaa
aactacggcgaagccatcgacattgccgtcaaacaagtggaagacggcgcgcagattatc
gacgtcaatatggacgaaggcatgctggacgccaaagcctgcatggtcaaattcctcaac
ttgctggcctccgagccggaagcctcccgcgtgccgatcatgatcgactcctccaaatgg
gaggtcatcgaagccggcttgaagtgcattcagggcaaaggcgtggtcaactccatttcc
ctgaaagaaggtgaagacgcttttatccgccaggccaaactggtcaagcagtacggcgcg
gcggcgattgtcatggcctttgacgaaaccggccaagccgacaccttggaacgcaaaatc
gaaatctgtaaacgctcctacgaggtcctgacccaaaaagtcggcttcccgccgcaggac
attattttcgacccgaacattttcgccgtcgccaccggtatcgaggaacacaacaattac
ggcctcgatttcatcaacgccgtcacctggattaaagccaacctgccacacgccaagatt
tccggcggggtgtccaacgtctccttctccttccgcggcaacaaccccgtgcgcgaagcc
atccactccgtgttcctctattacgccatcaaagaaggcatggacatgggcatcgtcaac
gccgggcaaatggcgatttacgacgacctgccggaaaaactccgtcaagccgtggaagac
gtcatcctcaataaagacccggaagccggcgaacgtttattggaagtggccgaagaattc
cgtggcgacggccaagccgccagcaaagtcgccgacaccgcctggcgcgaacaaagcgtg
gaaaaacgtctggaacacgcgctggtcaaaggcattaccgactacatcgaagccgacacc
gaagaagcttaccaaaaactcggctccggcctgcacgtcatcgaaggcccgctgatggac
ggcatgaacgtggtcggcgacctgttcggctccggcaaaatgttcctgccgcaagtggtc
aaatccgcccgcgtcatgaaacgcgccgtcgcctatctggatccatacctgctggccgcc
aagaccgaaggtcagcaacagggcaaaatcgtcatggccacggtcaaaggcgacgttcac
gacatcggcaaaaacatcgtcggcgtggtgttgcagtgtaataatttcgaagtgattgat
ttgggtgtcatggtgcccgctgagaaaattctcgacaccgccgtcgaacaaggggccaat
gtcatcgggctgtccggcctgattacgccatcactggaagaaatggtcaatgtcgccaaa
ctgatgaaagaacgcggcatggacttgccgttgctcatcggcggcgccaccacctccaaa
gcgcacaccgccgtgaaaatcgaaccgcaatacgaccatccggtggtgtacgtcaaagac
gcctcccgtgccgtcggcgtggcgcaaagcctcatttccaacgacctgaaagtcgatttc
gccgccaaaatccgcgccgaatacgaacaggttcgggaagaacgcaaagcccgcgcccag
caggtcaagcgcatcccaatcaaacaagcgcgcaccaatcccgccttaaccgaccaagcc
tggcaggaattcactccggtgcgtcccaaattcctcggcactaaagtgctggacaacttc
ccgctggaaaaactggtcgaacgctttgactggtcgcctttcttccaggcctgggaatta
cacggaaaatacccgcgcattctcgacgacaaagtcgtcggcgaagaagcccgcaaagtg
tttgccgacgcccaaaccatgctcaagcaaatcatcgacgaaaaatggctcaccgccaaa
gccgtgtacggtttctatccggccaaccgcgtcggcgacgacattgaagtctatgccgac
gaaagccgaaaccaagtgctgtacactttccatcacctgcgccagcaggccgagaaaaag
cgtggcggcgccaacaactgcctgtcggacttcatcgccagcaaagaaagccgcgtaccg
gactacatcggcttcttcgccgtcaccgccggcatcggcattgacgaacacgtggaacgc
tttgaaaaagaccacgacgactatcacgccattatgctcaaagccctggccgaccgcttt
gccgaagcctttgccgaaaccctgcatgaaatcgtgcgtaaggacgattggggctacgcg
ccggacgaaaacctcgacaacgaagacctgattaaagaacgttaccaaggcattcgcccc
gccgccggttacccggcctgcccggaccacaccgaaaaaggcaccctttgggaactgctg
aaaccggacgaaaccatcgggctggacattaccgaaagctttgccatgacgccaacggcc
gccgtttccggcacctacttcgcgcacccggaaagccgctacttcggcgtcggctcactc
ggccgcgaccaagtagaagactacgcccaccgcaaaggctggagcatcgaagaaacggaa
aaatggttggccccgaatttggggtatgaccccgaggattttgcgaattaa

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