Hydrogenovibrio thermophilus: EPV75_05660
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Entry
EPV75_05660 CDS
T05808
Symbol
aceE
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring), homodimeric type
KO
K00163
pyruvate dehydrogenase E1 component [EC:
1.2.4.1
]
Organism
htr
Hydrogenovibrio thermophilus
Pathway
htr00010
Glycolysis / Gluconeogenesis
htr00020
Citrate cycle (TCA cycle)
htr00620
Pyruvate metabolism
htr00785
Lipoic acid metabolism
htr01100
Metabolic pathways
htr01110
Biosynthesis of secondary metabolites
htr01120
Microbial metabolism in diverse environments
htr01200
Carbon metabolism
htr01210
2-Oxocarboxylic acid metabolism
Module
htr_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
htr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EPV75_05660 (aceE)
00020 Citrate cycle (TCA cycle)
EPV75_05660 (aceE)
00620 Pyruvate metabolism
EPV75_05660 (aceE)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EPV75_05660 (aceE)
Enzymes [BR:
htr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EPV75_05660 (aceE)
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Gene cluster
GFIT
Motif
Pfam:
PDH_E1_M
Transketolase_C_1
Transketolase_N
Transketolase_C
Transket_pyr
Motif
Other DBs
NCBI-ProteinID:
QAB15188
UniProt:
A0A410H2M5
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All DBs
Position
1217339..1219999
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AA seq
886 aa
AA seq
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MNDKFVDQDPQETQEWIDALEAVVSFEGSDKAQHIIGSLIEKARVHGIDIPYSANTPYIN
TIAPEEQSNYPGDVGLERKLRALLRWNAMAMVTRANKTTSVGGHIASYASSCTLYEVGMN
HFFKGPKHEQGADMVFFQGHTAPGMYARSFMEGRLDVDQLHNFRQEVDGNGLSSYPHPWL
MQDYWQFPTVSMGLGPLMAIYQARFMKYMQARGLSETQGRKVWAFLGDGEMDEPESRGAL
QLAKREKLDNLIFVINCNLQRLDGPVRGNDKIIQELEGVFRGAGWNVIKVIWGSGWDRLL
AKDTTGKLIERMGEVVDGEYQAYKAKDGAFVREHFFGKYPETAELVKDMTDDEIFRLTRG
GHSPRKIYNAYKRATETQGQPTVILAKTIKGYGMGKYGEAANTAHQQKKLDLEGLKYFRD
RFSVPVSDEELEKDIPFHRPDENSDIIKYMKERREALGGELPARQDNAEPLLVPELSAFK
MLTEGTEDREMSTTMAFVRIISILLRDKKIGPRCVPIIPDEARTFGMEGLFRQVGIYDPA
GQLYEPMDSDQLMWYKEAANGQVFQEGINEAGAMSNWIAAATAYANYGVSMVPFYIYYSM
FGYQRIGDLAWAAGDSRARGFLMGGTAGRTTLEGEGLQHQDGHNLIQFDQVPNCISYDPT
FAYEMAVIIRDGIRRMFHDKEDVYYYITCMNENYSHPAMPEGSEEGILKGLYSFKKSDAK
HKNKVQLMGSGTIFREVIAAAEMLESEWDVAADIWAAPSFNLLRRDGIETARWNALHPTE
TQKLSYCEATLSGSEGPFIAATDYIRDYPNRIREYVPGEFYVLGTDGFGRSDTREQLRKF
FEVDRYYVVVESLKALADAGSIKPEVVQKAIEKYGIDSEKPYPVHA
NT seq
2661 nt
NT seq
+upstream
nt +downstream
nt
atgaacgataagttcgttgatcaagatccacaagaaacacaagagtggatcgatgcatta
gaggcggtcgtctctttcgaaggctccgacaaggcgcaacacattattggctccttgatc
gagaaagcccgtgtccacggaatcgacattccttattccgcaaacaccccttacatcaac
accattgcaccggaagagcaaagcaactacccgggtgacgttggcctggaacgtaaactc
cgcgccttattgcgctggaatgccatggcaatggtgacgcgtgcgaacaaaaccaccagt
gtcggggggcatatcgcgtcttatgcatccagctgtactttgtatgaagtcgggatgaac
cacttcttcaaagggccaaaacacgaacaaggtgccgatatggtgttcttccaagggcac
accgcaccggggatgtacgcacgttcctttatggaagggcgtctggatgtggatcaactg
cataacttccgtcaggaagtcgacggcaacggcttatcgtcttaccctcacccttggttg
atgcaggattactggcagttcccaaccgtttccatgggcttggggcctttgatggccatt
taccaagcgcgtttcatgaaatacatgcaagcacgcggcttgtccgaaacccaaggtcgt
aaagtctgggcgttcctgggcgacggtgaaatggatgaaccggaatcccgtggtgctttg
cagttggccaagcgtgagaagctggacaacttaattttcgtcatcaactgtaacctacag
cgtttggatggcccggttcgtggtaatgacaaaatcattcaggaactagaaggcgttttc
cgtggcgccggttggaacgtcatcaaagtgatttggggctccggctgggatcgtttgctg
gcaaaagacaccaccggtaaactgatcgagcgtatgggcgaagtcgtggacggtgagtac
caggcttacaaagccaaagatggtgctttcgtgcgcgaacacttcttcggtaaatatccg
gaaaccgccgaactggtcaaagacatgaccgacgacgaaatcttccgtctgacgcgcggt
ggtcattcgccacgtaagatttacaacgcttacaagcgcgccaccgaaacacaaggacaa
ccaacggtcatcctggcgaaaaccatcaaaggttacgggatgggcaaatacggtgaagcg
gccaacaccgctcaccaacagaaaaaactggatttggaagggctgaaatacttccgtgac
cgtttctcggtgccggtttccgacgaagaactggaaaaagacattccgttccaccgtccg
gacgaaaactccgacatcatcaaatacatgaaagaacgccgtgaagccttaggcggtgaa
ttgccagcgcgtcaagacaatgccgagcctttactggttccggaattgtcggcgttcaaa
atgctgaccgaaggcaccgaagatcgtgaaatgtccacgaccatggcgtttgttcgtatc
atctccatcctgttgcgtgacaagaaaatcgggccacgttgtgtgccgattattccggat
gaagcacgtactttcgggatggaaggtctgttccgtcaagtcggtatctacgatccggca
gggcagctttacgagccaatggattccgaccaattgatgtggtacaaggaagccgccaac
gggcaagtgttccaagaagggattaacgaagccggcgccatgtccaactggattgcggca
gccaccgcttatgccaactacggtgtgagcatggtgcctttctacatttattattccatg
ttcggttatcagcgtatcggtgacttggcttgggccgccggggattcccgtgcacgtggt
ttcttgatgggcggcaccgccggtcgtaccacgctggaaggcgaaggcttgcagcaccag
gacggtcataacctgattcaattcgaccaagtgccgaactgtatttcttacgatccgaca
ttcgcttacgaaatggcggtcatcatccgtgacggtattcgtcgtatgttccacgataag
gaagacgtttactactacatcacgtgcatgaacgaaaactactcgcacccggccatgccg
gaaggatcggaagaaggcatcctgaaagggttgtactccttcaagaaatccgatgcgaag
cacaaaaacaaagtacaacttatgggctccggtaccatcttccgcgaagtcatcgcggcg
gcggaaatgctggaatccgaatgggatgtcgcggcggatatctgggcggctccaagtttc
aacctgttgcgtcgcgacggtattgaaaccgcacgctggaatgcgttgcacccgaccgag
acacaaaaactgtcttactgtgaagccactttatctggttcggaaggaccatttattgcg
gcaaccgactatattcgcgattacccgaaccgtattcgtgaatatgttccaggtgagttc
tatgtattagggaccgacggcttcggacgttccgatacacgtgaacaactgcgtaagttc
ttcgaagtggatcgctactacgttgtcgtggaatctttgaaagcgttggccgatgctggc
agcatcaagccggaagttgttcagaaagcaattgagaaatacgggattgatagtgaaaaa
ccttacccggttcatgcttga
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