KEGG   Ilyobacter polytropus: Ilyop_2427
Entry
Ilyop_2427        CDS       T01337                                 
Name
(GenBank) methionine synthase (B12-dependent)
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
ipo  Ilyobacter polytropus
Pathway
ipo00270  Cysteine and methionine metabolism
ipo00450  Selenocompound metabolism
ipo00670  One carbon pool by folate
ipo01100  Metabolic pathways
ipo01110  Biosynthesis of secondary metabolites
ipo01230  Biosynthesis of amino acids
ipo04980  Cobalamin transport and metabolism
ipo04981  Folate transport and metabolism
Module
ipo_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:ipo00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    Ilyop_2427
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    Ilyop_2427
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    Ilyop_2427
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    Ilyop_2427
   04980 Cobalamin transport and metabolism
    Ilyop_2427
Enzymes [BR:ipo01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     Ilyop_2427
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding B12-binding_2
Other DBs
NCBI-ProteinID: ADO84186
UniProt: E3HDK0
LinkDB
Position
pILYOP01:537222..540647
AA seq 1141 aa
MRELLKEKILILDGAMGTAIQNYSLEESDFRGELFSHIKGSLRGCNELLNLTKPEVLEEI
HLSYLEAGADIIETNTFNSNRISMREYGLEEKSYDLSKAGAELAVKAARKYEYDNKKRIF
VAGSMGPTSKSASIPTGGDPFGREVSYSELKAAYKEQALGLFDGGVDAFLIETIFDGLNA
KAAVIAIEEVLEEKGEKLPIMISGTVDVNGKLLSGQSIESLIVAIDRDSIISYGLNCSFG
AKELIPLIKKLGKLTKKNISLYPNAGLPNEKGEYDETPHMTGSYVKELIENKDINILGGC
CGTTPEHIKVMAELAQGKSPRKTSMENLAGIVSGNDTVSLHEEFLVVGERNNVSGSRKFA
RLIREESYDEALDIARTQVEKGAKILDINLDDALLDSVEEMEKFIRLLQNDMILSKLPIM
IDSSNFDVIEKGLENLAGKGIVNSISLKDGEHEFLRKAAVVRKFGAALVVMAFDEKGQAV
SSERKKEICKRAYELLTSNNFPAEDIIFDPNVLTVGTGTEEDRMHGVDFIDSVKWIKENL
PGAGVSGGVSNLSFAFRGNNILRHTIHKIFLEEGEKAGMTMAIVNPGEDPGNITPEVRKA
VENLLAGDKNAVDEILNLSFEKSAKKTAEIKPVTVEERLKDYLLKGRSQGIEDDIKTALE
KYSPLQVIQEVLMEGMEEVGALFEKGELFLPQILRSAAVMEKAVEFLTPLIEAGGKEKNV
KGKVLMATVEGDVHDIGKNIVGTVLKCNGFDVVDLGVMVPKDQILEAILRHDVDMVTLSG
LITPSLMEMEKVAEMMAEQNMDIPLLIGGAAASELSTAVRIEPKYSGRVIHVTDASGTLP
VVSSLMSEKKSDFLDERKKKAEYLRDAYLKNKNKKEMHSLEEARKRRKKLDNAIEYPKEI
GKQFIEIALEDLEPLIDWDMLLHALKSKGNTQEKKVLDESKEILSKMKDMNIKAKCAFGI
FNLFKDEDTLIVSGEKDYELPMVRSQIGNETISMADFFSKEDHIGAFVISVPEIAGSDDY
ESIIYQLLGTRLAEAASEWMEKYVNDNIWRVNIRPAIGYPSVPDHSMKKEIFKLVDGAET
GAKLSSNYAMTPLSSVCGLYVSNPNSFYFDPGKISYDQLKELANLRGLSVDDMNALLGGI
V
NT seq 3426 nt   +upstreamnt  +downstreamnt
atgagagaattactaaaagaaaaaatacttatactggatggagctatgggtacggctatt
cagaattattctcttgaagaatctgactttagaggagaactcttttctcatattaaagga
agcctaaggggctgcaatgaacttctaaaccttactaaaccagaggttttagaggaaata
cacctttcatacttagaagccggagctgatataatagagacaaacacttttaacagcaat
agaatatcaatgagagaatacggactggaggaaaaatcctacgatctttcaaaagccggt
gctgagctagcagttaaagctgctagaaagtatgaatatgataacaaaaaaagaatattt
gtagctggttccatggggcctactagtaagagtgcctctataccaacagggggagatccc
ttcggaagagaggtatcctattcagaactaaaagctgcctataaagagcaggcacttggc
ttatttgacggcggtgtagatgcctttcttatagagacaatatttgacggtctcaatgca
aaggctgcagtcattgccatagaagaagtcctagaagaaaagggagagaaacttcctata
atgatatcagggacagtagacgtcaacggaaaacttctctctggtcagagtatagagtcc
ctcatcgtggcaatcgacagagattctattatttcctatggattaaactgctcttttggt
gccaaggagcttattccactaataaagaaacttggaaaacttacaaaaaaaaatatatca
ctttacccaaatgccggtctgccaaatgaaaaaggtgaatatgacgagacacctcacatg
acagggtcatatgtaaaggaactcatagaaaataaagatataaatatcctagggggatgc
tgcggaacaacgccagagcatataaaagtcatggcagaacttgctcaaggcaaatcccca
agaaaaacttctatggaaaacctggcaggtattgtatctggaaatgatactgtaagtctg
catgaagagtttcttgtagtaggagagagaaataacgtctcagggtctagaaaatttgct
agattgattagagaagaaagctatgatgaggctctagacatagctagaactcaggtagaa
aaaggagctaaaattttagatataaatctagatgatgcccttcttgattctgtagaagag
atggaaaaatttataagacttttgcaaaatgatatgattttatcaaaactccctataatg
atagactcttcaaactttgatgtaatagaaaaaggtcttgaaaatctcgcaggaaaaggt
attgtaaactctatcagtttaaaagatggagagcatgaatttctgagaaaagcagcagtt
gtgagaaagtttggtgcagcccttgtggttatggcctttgatgaaaaaggacaggctgta
agctcagagagaaaaaaagaaatctgtaaaagagcttatgagcttttgacttcaaataat
ttcccggccgaggatattatctttgatccaaatgtcctcactgtaggaacaggaacagag
gaagacagaatgcacggggtagactttatagatagtgttaaatggataaaagaaaacctt
cccggtgcaggagtcagcggaggggttagtaatctttcctttgcttttagaggtaataat
atcctaagacatactattcataagatcttcctagaagagggagaaaaggccggcatgacc
atggctatagtaaatccgggagaagatccaggaaacataactcctgaggttagaaaagct
gtggaaaaccttcttgctggagataaaaatgcagtagatgaaattctgaatctctcattt
gagaagtcggcaaagaaaaccgcagaaataaagcctgtaactgtagaggaaaggctcaag
gattatctccttaagggaagaagccagggtatagaggacgatatcaagactgctctcgaa
aaatactcacctcttcaagttatacaggaagttctgatggagggaatggaagaggtagga
gctctttttgaaaagggtgaacttttccttccacagatacttaggtcagcagcagttatg
gaaaaagctgtggagttcctaactcctcttatagaggcaggaggaaaagaaaaaaatgta
aagggaaaagtccttatggcaacagtagaaggagatgttcatgatatagggaaaaatatc
gttggtactgtattaaagtgtaatggctttgatgttgtggaccttggtgttatggttcct
aaggatcagatattagaagctattctaaggcatgatgtagatatggttacattgagtggt
cttattaccccttctcttatggagatggaaaaagtggcagaaatgatggctgaacaaaat
atggatataccccttctaataggaggtgcggcggcttcagaactaagtactgcagtaaga
atcgaacctaagtattctggtagagtaatacatgtaacagatgcctcagggacacttcca
gtggtatcatcattgatgtctgaaaaaaaatcagattttcttgatgaaagaaaaaagaaa
gcagagtatctcagagatgcttatttgaaaaataaaaacaagaaagagatgcactcttta
gaagaagccagaaaaagaagaaaaaaattagacaatgccatagagtatcctaaagagatt
ggaaaacaatttatagagatagcgttagaagacttagagccactgatagactgggatatg
ctcttacatgcactaaagtctaagggaaatactcaggagaaaaaagtattggatgaatct
aaagaaattctctcaaaaatgaaagatatgaacataaaggcaaaatgtgcctttggtata
tttaaccttttcaaagatgaggatacccttatagtcagtggagagaaagattacgaactg
cctatggtcagaagtcagattggaaatgagacaatttccatggctgatttcttctcaaaa
gaggatcatataggggcctttgtaatatctgtgcctgagatagctggtagtgatgattat
gaatcaattatatatcagcttttagggactaggcttgcagaagcggcatcagagtggatg
gaaaaatatgtaaatgacaatatatggagggtgaatataagaccagccataggttatcca
tcggttccagatcattctatgaaaaaagagatatttaaacttgtagatggtgcggaaact
ggtgctaagctctcgagtaattatgccatgactcctttgtcatctgtatgcggattatat
gtatctaatccaaatagtttttattttgatccaggaaaaataagttatgaccagctaaaa
gagttggcaaatctaaggggtctgtctgtagacgatatgaatgccctcttaggtggcata
gtataa

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