Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101956834
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Entry
101956834 CDS
T10664
Symbol
Brca1
Name
(RefSeq) breast cancer type 1 susceptibility protein
KO
K10605
breast cancer type 1 susceptibility protein [EC:
2.3.2.27
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01524
Platinum drug resistance
iti03440
Homologous recombination
iti03460
Fanconi anemia pathway
iti04120
Ubiquitin mediated proteolysis
iti04151
PI3K-Akt signaling pathway
iti05206
MicroRNAs in cancer
iti05224
Breast cancer
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
101956834 (Brca1)
09124 Replication and repair
03440 Homologous recombination
101956834 (Brca1)
03460 Fanconi anemia pathway
101956834 (Brca1)
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
101956834 (Brca1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
101956834 (Brca1)
09162 Cancer: specific types
05224 Breast cancer
101956834 (Brca1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
101956834 (Brca1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
iti01009
]
101956834 (Brca1)
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
iti04121
]
101956834 (Brca1)
03036 Chromosome and associated proteins [BR:
iti03036
]
101956834 (Brca1)
03400 DNA repair and recombination proteins [BR:
iti03400
]
101956834 (Brca1)
Enzymes [BR:
iti01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
101956834 (Brca1)
Protein phosphatases and associated proteins [BR:
iti01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101956834 (Brca1)
Ubiquitin system [BR:
iti04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
Other single Ring-finger type E3
101956834 (Brca1)
Multi subunit type E3
BRCC complex
101956834 (Brca1)
Chromosome and associated proteins [BR:
iti03036
]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
101956834 (Brca1)
DNA repair and recombination proteins [BR:
iti03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
BRCA1-core complex
101956834 (Brca1)
BRCA1-A complex
101956834 (Brca1)
BRCA1-B complex
101956834 (Brca1)
BRCA1-C complex
101956834 (Brca1)
BRCA complex
101956834 (Brca1)
FA (Fanconi anemia) pathway
Downstream FA components
101956834 (Brca1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BRCT_assoc
BRCT
zf-C3HC4_4
zf-C3HC4_2
zf-RING_UBOX
BRCT_2
zf-C3HC4
zf-RING_2
zf-Nse
zf-RING_6
BRCT_3
zf-RING_5
RING_XB3-XBAT31
zf-C3HC4_3
Motif
Other DBs
NCBI-GeneID:
101956834
NCBI-ProteinID:
XP_040124893
LinkDB
All DBs
Position
Unknown
AA seq
1884 aa
AA seq
DB search
MLCSGSMEQKEMDLSAVRVEEVQNVLNAMQKILECPICLELIKEPVSTKCDHIFCKSLQE
STRFSQLVEELLKIIHAFELDTGLQFANSYNFPKKENNSPEHLKEEISIIQSMGYRNRAK
RLRESEPENPTLQETSLSVQLSNLGIMKSLRTKQQIQPQNKSVYIELGSDSSEDTVNKAN
YCSVRDQELLQTTTQGARAETSVDSANKAACEFSEKDIANIEHHQSSNKDLNIIEKHATE
RHPEKYQGISVSNLHVEPCGTNTRASSLQHENSSLLLTKDRMNVEKAEFCNKSKQPGLAR
SQQSRWAKSKETCNDRQTLSTGKKVDLNVDPLYEKKEPSKQKPPCSENSRDTQDVPWITR
NSSIRKVNEWFSRSDEMLTSDDSHDGGSESNAKVAGVLEIPNEVDGFSGSSEKIDLLATD
PHNALIFKRERICSKAVESNIEDKIFGKTYRRKASLPNLSHVTENLIIGAFAAEPQITQE
CTLTNKLKRKRRTTSCLHPEDFIKKADLAVVQKTPEKINQGTDQMEQNDQVMNITNSDQE
NETKVDYVQKEKNANTIESLEKESAFRTKAEPISSSISNMELELNIHNSKAPTKNRLRRK
SSTKHIHALELAVNRNTSPPHHIELQIDSFTSSEEIKTGNSNQMPVRHGKKLQLMEDAEP
AIEVKKRNQPNEQIIKRDTNDVFPGSKLTGISGLFTNCSSSSKVKEFVDPNLQKEGTEEN
IEIIQRSNNTKDPKDVLSGERGLQTERSAESTSISLVPDTDYGTQDSISLLEANTFGKAR
TTSNQHVTQYVAIENPKEFIHGHPKDTRNDTGGFKNSLRHDVNHIQEINVEMEESELDTQ
YLENTFQVSKRQSFALFSNPGNQEKECAAVYVPSQTLQKQSTEVNLECEQKDKNWGNKES
KIPNVQAINATMGFPVVCQKNKPGDDAKCNITEVSRICPSFLFRGSETKLITAYKHGILQ
NPYHMPSVSPIRSSVNTKCKKIEIIQRSNNTKDPKDVLSGERGLQTERSTESTLLGEKFE
KHSGSPEKIVGYKRIIQSTVSTISQNNIRESAFKEANSGSINEVGASTNEVGSSINEVGS
SGENIQTELGRNRGPKLNAVLRLGLMQPEAYKQNLSLINCKYPEIKRRGDDEVIQVVNTD
FSPCLISDNLEQPMRISPVTQVCSETPDDLLDDDDDEIKENTSFTEGGIKEKSAVFSKNV
QRGEFSRSPSPLAHTSLAQSHQKGARKLESSEENTCSEDEELPSFQHLLFGKVTKTPQST
KHSTIVTDCLSKKTEENLVSFRTGVNDCNNEVILEKASQEHDFSEEAKNSGSLFSSQCSV
LEDLTTNTNSQDPFLMFDPPSKQMKHQSENQEVVLSDNKLVSNDEERETGLEEDNHQEEQ
SVDSDLGEAASGYESETILSEDCSGVSSQSDILTTQQRDTMQDNLIKLQQEMAQLEAVLE
QHGSQSSDNSPSLVADSCAPEDLPDLEQNLSGEVLTSQKSNEYPVSLNPKKLSPDKFWVS
PNRSISKNKELEIKRSSPTSKSQLVDNRWSAHSHTTSLQNRNCPSQEDLIKIVDVEEQEL
KKSEPPDLMEQSYLPRQDLEGTPYLESGISLFSKDPDSDPPEDKDPEAVHVCNVPASTSA
LKLCQFQVGQSANSPAVAHTTSTAGYNAREESMSREKPEFTSPTERTKQRISMVVSGLTP
KELMLVHKFAKKHHIILSNLITEETTHVVMKTDAEFVCERTLKYFLGIAGGKWVVSYFWV
TQSIKERKILDEHDFEVRGDVVNGRNHQGPKRARESQGRKIFRGLKICCYGPFTNMPTDQ
LEWMVQLCGASVVKEIASLTLDTGAQPIVVIQPDAWTEDNGFHAIEQMCKAPVVTREWVL
DSVALYQCQELDTYLIPQISPSHC
NT seq
5655 nt
NT seq
+upstream
nt +downstream
nt
atgctttgctctggttcaatggaacagaaagaaatggatttatctgcagttcgtgttgaa
gaagtacaaaatgtccttaatgctatgcagaaaatcttagagtgtccaatttgtctggaa
ttgatcaaagaacctgtatccacaaagtgtgaccacatattttgcaaaagcctacaagaa
agtacaagatttagtcaacttgttgaagagctattgaaaatcattcatgcttttgagctt
gacacaggattgcagtttgccaacagttataactttccaaaaaaggaaaataactctcct
gaacatttaaaggaagagatttctatcatccaaagtatgggctaccgaaaccgtgccaaa
agacttcgagaaagtgaacctgaaaatcctaccttgcaggaaaccagtcttagtgtccaa
ctctctaaccttggaatcatgaaatctctgaggacaaagcagcagatacaacctcaaaat
aaatctgtctacattgaattgggatctgattcttctgaagatacagttaataaggcaaat
tattgcagtgtgagagaccaggaattgttgcaaaccaccactcaaggagccagggctgaa
accagtgtggattctgcaaataaggctgcttgtgagttttctgagaaggacatagcaaat
attgaacatcatcaatccagtaataaagatttgaacatcattgagaagcatgcaactgag
aggcatccagaaaagtatcagggtatttctgtttcaaacttgcatgtggagccatgtggc
acaaatactcgtgccagctcattacagcatgagaacagcagtttattactcactaaagac
agaatgaatgtagaaaaggctgaattctgtaataaaagcaaacagcctggcttagcaagg
agccaacagagcagatgggctaaaagtaaggaaacctgtaacgataggcaaactctcagc
acagggaaaaaggtagatctgaatgttgatcccctatatgagaaaaaagaaccaagtaag
cagaaacctccatgctctgagaattctagagatacccaagatgttccttggataacacga
aatagcagcattcggaaagttaatgagtggttttccagaagtgacgaaatgttaacttct
gatgactcacatgatgggggttctgagtcaaatgctaaagtagctggtgtattagaaatt
ccaaatgaagtagatggattttctggttcttcagagaaaatagacttgttggccactgac
ccgcataatgctttaatttttaaacgtgaaagaatctgctccaaagcagttgagagtaat
attgaagataaaatatttgggaaaacctatcggaggaaggcgagcctccctaacttgagc
catgtaactgaaaatctaattataggagcatttgccgcagaaccacaaataacacaagag
tgtaccctcacaaataaattaaagcgtaaaaggagaactacatcatgccttcatcctgag
gattttatcaagaaagcagatttggcagttgttcaaaagactcctgaaaaaataaatcag
ggaactgaccaaatggaacagaatgatcaagtaatgaatattactaatagtgaccaagag
aatgaaacaaaagttgattatgttcagaaagagaaaaatgctaacacaatagaatcattg
gaaaaagagtctgctttcagaactaaagctgaacctataagcagcagtataagcaatatg
gaactagaattaaatatccacaattcaaaagcacctacgaaaaataggctgaggaggaag
tcctctactaagcatattcatgcgcttgaactagcagtaaatagaaatacaagtccacct
catcacattgaattacaaattgatagttttactagcagtgaagaaataaagacaggaaat
tccaaccaaatgccagtcaggcatggcaaaaagcttcaactcatggaagatgcagaacct
gcaattgaagtcaagaagaggaaccagccaaatgaacaaataattaagagagataccaat
gatgttttcccaggatcaaagttaacaggcatatctggtctttttactaactgctcaagt
tctagtaaagttaaagaatttgttgatcctaaccttcagaaagaaggaacagaagagaac
atagaaataattcaaaggtctaataataccaaagaccccaaagatgtgctaagtggagaa
aggggtttgcaaactgaaagatctgcagaaagtaccagtatttcattggtacctgatact
gattatggcactcaggacagtatctcattactggaagctaacacttttggaaaagcaaga
acaacatcaaatcaacatgttactcagtatgtggcaatcgaaaaccccaaggaatttatc
catggtcatcctaaagatactagaaatgacacagggggtttcaagaattcattgagacac
gatgttaaccacattcaggagataaatgtagaaatggaagaaagtgaacttgatactcag
tatttagagaatacattccaagtttcaaagcgtcagtcatttgctctgttttcaaatcca
ggaaatcaagaaaaggaatgtgcagctgtctatgttccctctcagaccttacagaaacaa
agcacagaagtcaatcttgaatgtgagcaaaaagacaaaaattggggaaataaagagtct
aaaattccgaatgtccaggcaattaatgccactatgggcttccctgtggtttgtcagaaa
aataagccaggtgatgatgccaaatgtaatattacagaagtctctagaatttgtccttca
tttctgttcagaggcagtgaaactaaacttattactgcatataaacatggaattttacaa
aacccatatcatatgccatcagtttctcccatcaggtcatctgttaacactaaatgtaag
aaaatagaaataattcaaaggtctaataataccaaagaccccaaagatgtgctaagtgga
gaaaggggtttgcaaactgaaagatctacagaaagtaccctattaggggaaaagtttgag
aaacattcagggtcacctgaaaaaatagtgggatataagagaatcattcaaagtacagtg
agcacaattagccaaaataacattagagaaagtgcttttaaagaagccaactcaggcagt
attaatgaagtaggcgctagtactaatgaagtaggctccagtattaatgaagtaggttcc
agtggtgaaaacattcaaacagaactaggtagaaacagaggacccaaattaaatgctgtg
cttagattaggtcttatgcaacctgaagcctataaacaaaatctttctcttattaattgt
aaataccctgaaataaaaagacgaggagatgatgaagtgattcaagttgttaatacagat
ttctctccatgtctaatttcagataatttagaacaacctatgagaattagtcctgtcact
caggtttgttctgagactccagatgacctgttagatgatgatgatgatgaaataaaggaa
aataccagctttactgaaggtggcattaaggaaaaatctgctgtttttagtaagaatgtc
cagaggggagaatttagcaggagcccaagccctttagcccatacatctttggctcagagt
caccaaaagggggccaggaaattagagtcctcagaagagaacacctgtagtgaggatgaa
gaacttccctccttccaacacttactatttggtaaagtaaccaaaacacctcagtctacc
aaacacagcactattgtgacagactgtctgtctaagaaaacagaggagaacctggtatca
tttaggactggtgtaaatgactgcaataatgaggtgatactcgaaaaggcctcccaggaa
catgactttagtgaggaagcgaaaaactctggtagcttgttttcttcccagtgcagtgta
ttagaagacttgacaacaaatacaaactcccaggaccccttcttgatgtttgatcctcct
tccaaacaaatgaaacatcagtctgaaaaccaggaagttgtgctgagtgacaacaaattg
gtttcaaatgatgaagaaagggaaactggcctagaagaagataatcaccaagaagagcag
agtgtggattcagacttaggtgaagcagcatctggctatgaaagtgaaacaatcctctct
gaagattgctcaggggtgtcttcgcagagtgatattttaaccactcagcagagggatacc
atgcaagataacctgataaagctccagcaggaaatggctcaactggaagcagtgctggaa
cagcatgggagccagtcttctgacaactccccttccctggtagctgactcttgtgcccct
gaggatctgccagatctggaacaaaacctatcaggtgaagtgttaacgtcacagaaaagt
aatgaatatcctgtaagtctgaatcctaaaaagctttctcctgacaagttctgggtatct
ccaaatagatccattagtaaaaacaaagaattggaaataaaaaggtcttctcccacttct
aaatcccagttggtagataataggtggtctgcacatagtcacactacgagtcttcaaaac
agaaactgtccctctcaagaggatctcattaagattgttgatgtggaagagcaagaactg
aaaaagtctgagccacctgatttaatggaacaatcttacttgccaaggcaagatctagag
ggaaccccttacctggaatctggaatcagcctcttctctaaggatcctgattctgatccc
cctgaagacaaagacccagaggcagttcatgtttgcaatgtaccagcttcaacctctgca
ttgaaattatgccaatttcaagttggacaatctgccaacagtccagctgttgctcacact
actagtactgctgggtataacgcacgggaagaaagtatgagcagggagaagccagaattc
acatctccaacagaaaggaccaagcagagaatatccatggtggtatcgggcttgaccccc
aaagaacttatgcttgtacacaagtttgccaaaaaacaccatatcattttaagtaatcta
attactgaagagactactcacgtcgttatgaaaacagatgctgagtttgtgtgtgaacgg
acactgaaatattttctcggaattgcaggaggaaaatgggtagttagctatttctgggtg
acccagtctattaaagaaagaaagatcctagatgagcatgattttgaagtcagaggagat
gtagtcaatggaagaaaccaccaaggtccaaagcgagcaagagaatcccagggcagaaag
atcttcaggggcctaaaaatctgttgctatgggccttttaccaacatgcccacagatcaa
ctggaatggatggtgcaactgtgtggagcttctgtggtaaaggaaattgcgtcactcacc
cttgacacgggtgctcagccaattgtggttatacaaccagatgcctggacagaagacaat
ggcttccatgcaattgaacagatgtgtaaggcacctgtggtgaccagagagtgggtgttg
gacagtgtagccctctaccaatgccaggagctggacacctacctgataccacagatctca
cccagccactgctga
DBGET
integrated database retrieval system
