Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101960408
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Entry
101960408 CDS
T10664
Symbol
Cacna1c
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti04010
MAPK signaling pathway
iti04020
Calcium signaling pathway
iti04022
cGMP-PKG signaling pathway
iti04024
cAMP signaling pathway
iti04260
Cardiac muscle contraction
iti04261
Adrenergic signaling in cardiomyocytes
iti04270
Vascular smooth muscle contraction
iti04713
Circadian entrainment
iti04720
Long-term potentiation
iti04723
Retrograde endocannabinoid signaling
iti04724
Glutamatergic synapse
iti04725
Cholinergic synapse
iti04726
Serotonergic synapse
iti04727
GABAergic synapse
iti04728
Dopaminergic synapse
iti04742
Taste transduction
iti04911
Insulin secretion
iti04912
GnRH signaling pathway
iti04921
Oxytocin signaling pathway
iti04924
Renin secretion
iti04925
Aldosterone synthesis and secretion
iti04927
Cortisol synthesis and secretion
iti04929
GnRH secretion
iti04930
Type II diabetes mellitus
iti04934
Cushing syndrome
iti04935
Growth hormone synthesis, secretion and action
iti05010
Alzheimer disease
iti05020
Prion disease
iti05022
Pathways of neurodegeneration - multiple diseases
iti05031
Amphetamine addiction
iti05207
Chemical carcinogenesis - receptor activation
iti05410
Hypertrophic cardiomyopathy
iti05412
Arrhythmogenic right ventricular cardiomyopathy
iti05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
101960408 (Cacna1c)
04020 Calcium signaling pathway
101960408 (Cacna1c)
04024 cAMP signaling pathway
101960408 (Cacna1c)
04022 cGMP-PKG signaling pathway
101960408 (Cacna1c)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
101960408 (Cacna1c)
04929 GnRH secretion
101960408 (Cacna1c)
04912 GnRH signaling pathway
101960408 (Cacna1c)
04921 Oxytocin signaling pathway
101960408 (Cacna1c)
04935 Growth hormone synthesis, secretion and action
101960408 (Cacna1c)
04924 Renin secretion
101960408 (Cacna1c)
04925 Aldosterone synthesis and secretion
101960408 (Cacna1c)
04927 Cortisol synthesis and secretion
101960408 (Cacna1c)
09153 Circulatory system
04260 Cardiac muscle contraction
101960408 (Cacna1c)
04261 Adrenergic signaling in cardiomyocytes
101960408 (Cacna1c)
04270 Vascular smooth muscle contraction
101960408 (Cacna1c)
09156 Nervous system
04724 Glutamatergic synapse
101960408 (Cacna1c)
04727 GABAergic synapse
101960408 (Cacna1c)
04725 Cholinergic synapse
101960408 (Cacna1c)
04728 Dopaminergic synapse
101960408 (Cacna1c)
04726 Serotonergic synapse
101960408 (Cacna1c)
04720 Long-term potentiation
101960408 (Cacna1c)
04723 Retrograde endocannabinoid signaling
101960408 (Cacna1c)
09157 Sensory system
04742 Taste transduction
101960408 (Cacna1c)
09159 Environmental adaptation
04713 Circadian entrainment
101960408 (Cacna1c)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
101960408 (Cacna1c)
09164 Neurodegenerative disease
05010 Alzheimer disease
101960408 (Cacna1c)
05020 Prion disease
101960408 (Cacna1c)
05022 Pathways of neurodegeneration - multiple diseases
101960408 (Cacna1c)
09165 Substance dependence
05031 Amphetamine addiction
101960408 (Cacna1c)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
101960408 (Cacna1c)
05412 Arrhythmogenic right ventricular cardiomyopathy
101960408 (Cacna1c)
05414 Dilated cardiomyopathy
101960408 (Cacna1c)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
101960408 (Cacna1c)
04934 Cushing syndrome
101960408 (Cacna1c)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
iti04040
]
101960408 (Cacna1c)
Ion channels [BR:
iti04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
101960408 (Cacna1c)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
CAC1F_C
PKD_channel
Etmic-2
DUF4834
Motif
Other DBs
NCBI-GeneID:
101960408
NCBI-ProteinID:
XP_040137050
LinkDB
All DBs
Position
Unknown
AA seq
2199 aa
AA seq
DB search
MVNENTRMYIPEENHQGSNYGSPRSANMNANAAAGLAPEHIPTPGAALSWQAAIDAARQA
KLMGSAGNATISTVSSTQRKRQQYGKPKKQSGTTATRPPRALLCLTLKNPIRRACISIVE
WKPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLKVIAYG
LLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALRAFRVL
RPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKTCYNQE
GIADVPAEEDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVFQCITM
EGWTDVLYWMQDAMGYELPWVYFVSLVIFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQ
KLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNRGTPAGLLDQKKGKFAWFS
HSTETHVSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKC
RAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKMYS
LGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKITRYWNSL
SNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLL
TVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLA
DAESLTSAQKEEEEEKERKKLARPARTASPEKKQEVVEKPAVEETKEEKIELKSITADGE
SPPTTKINMDDLQPNENEDKSSYPNPEAAGEEDEEEPEMPVGPRPRPLSELHLKEKAVPM
PEASAFFIFSPNNRFRLQCHRIVNHTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILG
NADYVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVV
KILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGK
LYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTF
EGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGE
QEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTI
CLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALIVVGS
IVDIAITEVNPRPRIPGIFVGDSLQLISVCLSLKPAEHTQCSPSMNAEENSRISITFFRL
FRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDT
TEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSS
FAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKG
RIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTAL
RIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRK
FKKRKEQGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAA
SEDDIFRRAGGLLVNHVNYYQSDSRGAFPQTFTTQRPLHINKAGNNQGDTESPSHEKLVD
STFTPSSYSSTGSNANINNANNTALGRFPRPSGYPSTVSTVEGHGPPLSPAIRVQEAAWK
LNSRRTHCYEILGRCSSRDSQLAMVCQEDGSREETYDVKMSEEAEYCSEPSLLSTEMLSY
QDDENRQLTPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLP
LHLVHHQALAVAGLSPLLQRSHSPTTFPRPCATPPATPGTRAWPPQPIPTLRLEGAESIE
KLNSSFPSIHCSSWSEETASCSGGSNTIRRARPVSLTVPTQAAAPGRQFHGSASSLVEAV
LISEGLGQFAQDPKFIEVTTQELADACDMTIEEMENAADSILSGGAQQSPNGTLLPFVNC
RDPGQDRAGGEEDGSCARALGRGRSEEELQDSRVYVSSL
NT seq
6600 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgaaaatacgaggatgtacattccagaggaaaaccaccaaggttccaactat
gggagcccgcgctcagccaacatgaatgccaacgcagctgcagggctcgcccctgagcac
atccccaccccaggggcagccctgtcttggcaagcagccatcgatgcagcccggcaggcc
aagctgatgggcagtgctggcaatgcgaccatctccacagtcagctccacgcagcggaaa
cggcagcagtatgggaaacccaaaaaacagagtggcacaactgccacgcggccaccccgt
gccctgctctgtctgaccctgaagaaccccatccggagagcatgtataagcatcgtcgaa
tggaaaccatttgaaataattattttactgactatttttgccaattgtgtggccttagca
atctatattccctttccagaagatgattccaatgccaccaattccaacctggaacgagtg
gaatatctctttctcataatttttactgtggaagcatttttaaaagtaatcgcctatggt
cttctctttcaccccaacgcttacctccgcaacggttggaatttactagattttataatt
gtggttgtagggctttttagtgcaattttagaacaagcaaccaaagcagatggggccaat
gctctcggagggaaaggggctggatttgacgtgaaggcgctgcgggctttccgtgtgctg
cgtcccctgaggctggtgtctggagtcccaagtctgcaggtggtcctgaactccatcatc
aaggccatggtgcccttgctgcacattgccctgctcgtgctgtttgtcatcatcatctac
gccatcatcggcctggagctcttcatggggaagatgcataagacgtgctataaccaggag
ggcatagcagatgttccagcagaagaggatccttccccctgtgctttagagacaggccat
gggcggcagtgtcagaacggcactgtgtgcaagcccgggtgggatggtcccaagcacggc
atcaccaacttcgacaatttcgcctttgccatgttgacagtgttccagtgcatcaccatg
gagggctggacggacgtgctgtattggatgcaggacgctatgggctatgagttaccctgg
gtgtattttgtcagtctggtcatctttggatcctttttcgttctaaatctggttctcggt
gtgttgagcggagagttttccaaagagagggagaaggccaaggctcggggagacttccag
aagctaagagagaaacagcagctggaagaagacctcaaaggctacctggactggatcacc
caggcggaagacatcgaccctgagaacgaggacgaaggcatggatgaggagaagccccga
aacagaggcactccagcgggcttgcttgatcagaagaaagggaagtttgcttggtttagt
cactccacagaaacccatgtgagtatgcccacaagtgagaccgagtccgtcaacaccgaa
aatgtggctggaggtgacatcgaaggagaaaactgcggggccaggctggcccaccggatc
tccaaatcaaagttcagccgctactggcgcagatggaatcggttctgcaggagaaagtgc
cgggccgcagtcaagtctaatgtcttctattggctcgtgatcttcctggtgttcctcaac
acgctcaccatcgcctcggaacattacaaccagccccactggctcaccgaagtgcaagac
acagccaacaaggccctactggcccttttcactgcagagatgctcctgaagatgtacagc
ctgggcctgcaggcctacttcgtgtccctcttcaatcgctttgactgcttcatcgtgtgt
gggggcatcctggagaccatcctagtggagaccaagatcatgtctcccttgggcatctct
gtgctgagatgcgtccggctgctgaggatatttaaaatcacaaggtactggaactcccta
agcaacctggtggcgtccttactgaactctgtgcggtccatcgcctccctgcttctgctt
ctcttcctctttatcatcatcttctccctcctggggatgcagctctttggaggaaagttc
aactttgatgagatgcagactcggaggagcacatttgataacttcccccagtccctcctc
actgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaattatatcctactgaatgtattcttggccattgctgtggacaacctggct
gatgctgagagtctcacctctgcccaaaaggaagaggaagaagagaaagagagaaagaag
ctggccagaccggccaggactgccagcccagagaagaaacaagaggtggtggagaagcca
gcagtggaggaaaccaaggaggagaaaattgagctgaaatccattactgctgatggagag
tctccccccaccaccaagatcaacatggacgacctccaacccaatgagaatgaggataaa
agttcctacccgaacccagaggctgcaggagaagaggatgaggaggagcccgagatgcct
gttgggccccgcccacgaccactgtctgagctgcaccttaaggaaaaggcagtgcccatg
ccagaagccagtgcgtttttcatcttcagccccaacaacaggtttcgccttcagtgtcac
cgcattgtcaatcacacgatcttcaccaatctgatcctcttcttcattctgctcagcagc
atttccctggctgctgaggaccccgtccagcacacctccttcaggaaccatatcctaggc
aatgcagactatgtcttcactagtatctttacattagaaattatccttaagatgactgct
tacggggctttcctacacaagggctctttctgccggaactacttcaacatcttagacctg
ctggtggtcagcgtgtccctcatctcctttggcattcagtctagtgcaatcaatgttgtg
aagatcttgcgagtcctgcgagtacttagacccctgagggccatcaacagggccaagggg
ctaaagcatgtagtccagtgtgtgtttgttgccatccggaccatcgggaacatcgtgatt
gtcaccacactgctgcagttcatgtttgcctgcatcggggtccagctcttcaagggaaag
ctctatacctgctcagatagttccaaacagactgaggcagaatgcaagggtaactatatc
acatacaaagacggagaggttgaccaccccatcatccagccccgcagctgggagaacagc
aagtttgacttcgacaatgttctggcagccatgatggctctcttcaccgtctcaaccttt
gaggggtggccagagctgctgtaccgctccatcgactcccacacggaagacaagggcccc
atctacaactaccgcgtggagatctccatctttttcatcatctacatcatcatcattgcc
ttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggagcagggagag
caagagtacaagaactgtgagctggacaaaaaccagcgacagtgtgtggaatatgccctc
aaggcccggcccctgcggaggtacatccccaagaaccagcaccaatacaaagtgtggtac
gtggtcaactctacctactttgagtacctgatgttcgtcctcatcctgctcaacaccatc
tgcttggccatgcagcactatggccagagctgcctgttcaagatcgccatgaacatcctc
aacatgctcttcactggcctcttcactgtggagatgatcctgaagctcatcgccttcaaa
cccaagcactatttctgtgatgcatggaatacatttgacgccttgattgttgtgggtagc
attgttgatatagcaatcaccgaggtaaacccaagacctagaataccgggcatcttcgtt
ggagactcattacagcttatctctgtctgcctttctttaaagccagctgaacatacccaa
tgctctccctctatgaatgcagaggagaactcccgcatctccatcaccttcttccgcctc
ttccgggtcatgcgcctggtcaagctgctgagccgtggggagggtatccggaccctgctg
tggaccttcatcaaatccttccaggccctgccctacgtggcccttctgatagtgatgctg
ttcttcatctatgcagtcattgggatgcaggtatttggaaaaattgccctgaatgatacc
acagagatcaaccggaacaacaattttcagaccttcccccaagctgtgctgctgctcttc
aggtgtgccacgggggaggcctggcaggacattatgctggcctgcatgccaggcaagaag
tgtgccccagaatccgagcccagtaacagcacagagggagagacgccctgtggcagcagc
ttcgccgtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctc
tttgtagctgtcatcatggacaactttgactacctgacaagggactggtcaatcctgggt
ccccaccacctggatgaatttaagaggatctgggcagagtatgaccctgaggccaagggt
cgcatcaaacacctagacgtggtgaccctcctccggcgtattcagccccccctggggttt
gggaagctgtgtcctcatcgtgtggcctgcaaacgtctggtctccatgaacatgcctctg
aacagcgatgggacagtcatgttcaatgccaccctgtttgccctggtcaggacagccctg
aggatcaagacagaagggaacctggagcaagccaatgaggagctgcgggccatcatcaag
aagatctggaaaaggaccagcatgaagctgctggaccaagtggtgcctcctgcaggtgat
gacgaggttacagttggcaaattttatgccactttcctgatccaagaatacttccggaaa
ttcaagaagcgtaaagagcaagggcttgtgggaaagccctcccagaggaacgccctgtca
ctgcaggctggcttgcgtacactgcacgacatcgggcctgagatccgaagggccatctct
ggagatctgactgccgaggaagagctggacaaggccatgaaggaggctgtgtctgctgcc
tccgaagacgacatcttcaggagggccgggggcctgctggtcaaccatgtcaactactac
caaagcgacagccggggcgccttcccacagaccttcaccacccagcgcccgctgcacatc
aacaaggcgggtaacaaccaaggcgacactgaatcgccctcccacgagaaactagtggac
tccactttcacccccagcagctactcatccaccggctccaacgccaacatcaacaatgcc
aacaacaccgccctaggccgcttcccccgccccagcggctaccccagcacagtcagcacc
gtggagggccatgggccccccttgtctcctgccatccgggtgcaggaggctgcctggaag
ctcaactccaggaggacacactgctatgagatactgggacggtgctcctcccgggacagc
cagttagccatggtgtgtcaagaggacgggtctcgagaggagacctacgacgtgaagatg
agcgaagaggccgagtactgcagcgagcccagccttctctccacagagatgctctcctac
caggatgatgaaaatcgacagttgacgcctccagaggaggacaagagggacatccggcaa
tctccaaagaggggtttcctccgctctgcctcactaggtcgaagggcctccttccaccta
gagtgtctgaagcgacagaagaatcaagggggagacatctctcagaagacagtcctaccc
ttgcatctggtccatcatcaggcattggcagtggcgggcctgagccctctcctccagaga
agccattcccccaccacgttccccaggccatgtgccacaccccctgccacacctggtacc
cgagcctggcccccacagcccatccccaccctaaggctggaaggagccgagtccatcgaa
aaactcaacagcagcttcccgtccatccactgtagttcctggtctgaggagaccgcctcc
tgcagtgggggcagcaacaccatcaggagagcccggccggtctccctcacggtgcccact
caggctgcggccccagggaggcagttccatggcagtgccagcagcctggtagaagcggtc
ttgatttcagaaggactggggcagtttgctcaagatcccaagttcatcgaggtcacgacc
caggagttggcggacgcctgcgacatgaccatagaggagatggagaacgcggccgacagc
atcctcagtgggggcgcgcagcagagccccaatggcaccctactaccttttgtgaactgc
agggacccggggcaggacagggcgggcggcgaggaggacgggagctgtgcgcgcgccctg
gggcgaggccggagcgaggaggagctccaggacagcagggtctacgtcagcagcctgtag
DBGET
integrated database retrieval system
