Ictidomys tridecemlineatus (thirteen-lined ground squirrel): 101973091
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Entry
101973091 CDS
T10664
Symbol
Ptk2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
iti Ictidomys tridecemlineatus (thirteen-lined ground squirrel)
Pathway
iti01522
Endocrine resistance
iti04012
ErbB signaling pathway
iti04062
Chemokine signaling pathway
iti04148
Efferocytosis
iti04151
PI3K-Akt signaling pathway
iti04360
Axon guidance
iti04370
VEGF signaling pathway
iti04510
Focal adhesion
iti04670
Leukocyte transendothelial migration
iti04810
Regulation of actin cytoskeleton
iti04935
Growth hormone synthesis, secretion and action
iti05100
Bacterial invasion of epithelial cells
iti05135
Yersinia infection
iti05146
Amoebiasis
iti05163
Human cytomegalovirus infection
iti05165
Human papillomavirus infection
iti05170
Human immunodeficiency virus 1 infection
iti05200
Pathways in cancer
iti05202
Transcriptional misregulation in cancer
iti05205
Proteoglycans in cancer
iti05208
Chemical carcinogenesis - reactive oxygen species
iti05222
Small cell lung cancer
iti05417
Lipid and atherosclerosis
iti05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
iti00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
101973091 (Ptk2)
04370 VEGF signaling pathway
101973091 (Ptk2)
04151 PI3K-Akt signaling pathway
101973091 (Ptk2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
101973091 (Ptk2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
101973091 (Ptk2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
101973091 (Ptk2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
101973091 (Ptk2)
04062 Chemokine signaling pathway
101973091 (Ptk2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
101973091 (Ptk2)
09158 Development and regeneration
04360 Axon guidance
101973091 (Ptk2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
101973091 (Ptk2)
05202 Transcriptional misregulation in cancer
101973091 (Ptk2)
05205 Proteoglycans in cancer
101973091 (Ptk2)
05208 Chemical carcinogenesis - reactive oxygen species
101973091 (Ptk2)
09162 Cancer: specific types
05222 Small cell lung cancer
101973091 (Ptk2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
101973091 (Ptk2)
05163 Human cytomegalovirus infection
101973091 (Ptk2)
05165 Human papillomavirus infection
101973091 (Ptk2)
09171 Infectious disease: bacterial
05135 Yersinia infection
101973091 (Ptk2)
05100 Bacterial invasion of epithelial cells
101973091 (Ptk2)
09174 Infectious disease: parasitic
05146 Amoebiasis
101973091 (Ptk2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
101973091 (Ptk2)
05418 Fluid shear stress and atherosclerosis
101973091 (Ptk2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
101973091 (Ptk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
iti01001
]
101973091 (Ptk2)
01009 Protein phosphatases and associated proteins [BR:
iti01009
]
101973091 (Ptk2)
Enzymes [BR:
iti01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
101973091 (Ptk2)
Protein kinases [BR:
iti01001
]
Non-receptor tyrosine kinases
FAK family
101973091 (Ptk2)
Protein phosphatases and associated proteins [BR:
iti01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
101973091 (Ptk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
101973091
NCBI-ProteinID:
XP_021579563
LinkDB
All DBs
Position
Unknown
AA seq
1140 aa
AA seq
DB search
MLLQLAGQEALKPAGAICMEKSGCSPFPMCWAKEYDRYLASSKIMAAAYLDPNLNHTPHS
SAKTHLGPGMERSPGAMERVLKVFHYFESNSEPTTWASIIRHGDATDVRGIIQKIVDSHR
VKHVACYGFRLSHLRSEEVHWLHVDMGVSSVREKYELAHPPEEWKYELRIRYLPKGFLNQ
FTEDKPTLNFFYQQVKSDYMLEIADQVDQEIALKLGCLEIRRSYWEMRGNALEKKSNYEV
LEKDVGLKRFFPKSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKE
CFKCALGSSWIISVELAIGPEEGISYLTDKGCNPTHLADFNQVQTIQYSNSEDKDRKGML
QLKIAGAPEPLTVTAPSLSIAENMADLIDGYCRLVSGATQSFIIRPQREGERALPSIPKL
ANSEKQGVRTHAVSVSGVSHCQHKVKKARRFLPLVFCSHEPSPADEISGDETDDYAEIID
EEDTYTMPSKNYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAIKT
CKNCTSDSVREKFLQEALTMRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRK
YSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMEDST
YYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIGRI
ENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKAQQEERMRMES
RRQATVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQSNHYQVSGYPGPHGLTA
MAGSIYPGPASLLDQSESWNHRPQEIPLWQPNMEDSTSLDLRGMGQVLPAHLMEERLIRQ
QQEMEEDQRWLEKEERFLKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPAAPPKK
PPRPGAPGHLGSLASLSSPGDSYNEGVKPWRLQPQEISPPPTANLDRSNDKVYENVTGLV
KAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETIPVLPASTHREIEMAQKLLNS
DLGELISKMRLAQQCAMTSLQQEYKKQMLTAAHALAVDAKNLLDAIDQARLKMLGQARPH
NT seq
3423 nt
NT seq
+upstream
nt +downstream
nt
atgttgttgcaactggcaggccaggaggccctgaaaccagcaggtgccatctgtatggag
aaaagcggctgtagtccatttccaatgtgttgggctaaagaatatgatagatacctagca
tccagcaaaataatggcagctgcttaccttgatcccaacttgaaccacacgccacactca
agtgctaagacccacctgggtcctggcatggaacgttcccctggtgccatggagcgagta
ttgaaggtctttcattattttgaaagcaatagtgagccaaccacctgggccagtattatc
aggcatggagatgctactgatgtcaggggcatcatccagaagatagtggacagccacaga
gtgaagcacgtggcttgctacgggttccgcctcagccacctgcggtcggaggaggttcac
tggctgcatgtggacatgggtgtctccagcgtgagggagaagtatgagcttgcccatcct
ccggaggagtggaaatatgaattaaggattcgttacttgccaaaaggatttctgaaccag
tttactgaagacaagccaactctgaatttcttctaccaacaggtaaagagcgactacatg
ctagagatagcagaccaagtggaccaggaaattgctttgaagttgggttgtctagaaata
cggcgatcatactgggagatgcgcggcaatgcactggaaaagaagtctaactatgaagtg
ttagaaaaagatgttggtttaaagcgattttttcctaagagtttactggattctgtcaag
gccaaaactttaagaaaactgatccaacaaacatttagacagtttgccaaccttaataga
gaagaaagtattctgaaattctttgagatcctctctccagtgtacagatttgataaagaa
tgcttcaagtgtgccctggggtcaagctggattatttcagtggaactggcaatcggcccc
gaagaagggatcagttacctaacagacaagggctgcaatcccacacatctggctgacttc
aaccaagtgcagaccattcagtattccaacagtgaagacaaagacagaaaaggaatgcta
cagctcaaaatcgcaggtgcacccgagcctctgacagtgacagccccatccctgagcatc
gccgagaacatggcggacctaatagacgggtactgccggctggtgagcggagccacgcag
tccttcatcatcagacctcagagagaaggtgaacgggcattgccatcaatacccaagttg
gccaacagtgagaagcaaggcgtacggacacatgcggtctctgtgtcaggagtcagtcac
tgccaacataaagttaagaaagctaggcgctttctccctttggtcttctgttcccatgaa
ccttctcctgccgatgaaattagtggggacgagacggacgactatgccgagataatcgat
gaagaagatacttacaccatgccctcaaaaaactatggaatagatgaagccagggactat
gagattcaaagagaaagaatagaactcggacgctgtattggagaaggccagtttggagat
gtgcatcaaggcgtgtacatgagtccagagaatccagctttggctgtcgcaattaaaaca
tgtaaaaactgtacttcggacagcgtgagagagaaattccttcaagaagccttaacaatg
cgtcagtttgaccatcctcacattgtgaagttgattggcgtcatcacagagaaccccgtg
tggataatcatggagctgtgcacactgggagagctgaggtcatttttgcaagtaaggaaa
tacagcttggatctggcatctctgatcctatatgcctatcagctcagtactgcactggcg
tatctggagagcaaaagatttgtacacagggacattgctgctcgaaatgtcctggtatcc
tcaaatgattgtgtaaaattaggagacttcggattatctcggtacatggaagacagtact
tactacaaagcttccaaaggaaaattgcctattaaatggatggctccagagtcaatcaat
tttcgacgttttacctcagctagtgacgtgtggatgtttggtgtatgtatgtgggagatt
ctgatgcatggtgtgaagccttttcaaggagtgaagaacaatgatgtgatcggtcgaatt
gaaaatggggaaagattaccaatgcctccaaattgtcctcctaccctctacagccttatg
acgaaatgctgggcctatgaccccagcaggcggcccaggtttactgaacttaaagcgcag
ctcagcacgatcctggaggaagagaaggctcaacaggaagaacggatgaggatggagtcc
agaagacaggccaccgtgtcttgggactctggagggtccgacgaagcaccacccaagccc
agcagacctggttaccctagtcctcgctccagtgaaggattttaccccagtccacagcac
atggtgcagagcaatcattatcaggtgtctggctaccctggtccacatggactcacagcc
atggctggcagcatctaccccggcccagcatctctcttggaccaatcagaatcgtggaat
cataggccccaggagatacccctatggcagcccaacatggaggactcgacatcactggac
ctgagaggaatggggcaggtgttgcccgcccacctgatggaagagcgactgatccgacag
cagcaggaaatggaagaagatcagcgctggctggagaaagaggagagatttctgaaacct
gatgtgaggctatctcgaggcagcattgacagggaggacgggagtcttcagggtccgact
ggaaaccaacacatctatcagcctgtgggcaaaccagatcctgcagctccaccaaagaaa
cctccacgccccggagcccctggccacctgggcagcctcgccagcctcagcagccctggg
gacagctacaacgagggggtcaagccatggaggcttcaaccccaggaaatcagtccccct
cccactgccaacctggaccggtccaatgacaaggtgtatgagaacgtgacgggcctggtg
aaagctgtcatcgagatgtccagtaaaatccagccagccccacccgaggagtacgtccct
atggtgaaggaagttggcttggccctgcggacactattggctaccgtggatgagaccatt
cctgtcctcccagccagcacacaccgagagatcgagatggcacagaagctgctcaactct
gacctgggagagctcatcagcaagatgcggctggcccagcagtgcgccatgaccagcctg
cagcaggagtacaagaagcaaatgctgactgccgcccacgccctcgcagtggatgccaag
aacctgctggatgccattgaccaggcgagactgaagatgcttgggcaggcaaggccgcat
tga
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