Klebsiella africana: LGL98_06035
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Entry
LGL98_06035 CDS
T07696
Symbol
tyrA
Name
(GenBank) bifunctional chorismate mutase/prephenate dehydrogenase
KO
K14187
chorismate mutase / prephenate dehydrogenase [EC:
5.4.99.5
1.3.1.12
]
Organism
kar
Klebsiella africana
Pathway
kar00400
Phenylalanine, tyrosine and tryptophan biosynthesis
kar00401
Novobiocin biosynthesis
kar01100
Metabolic pathways
kar01110
Biosynthesis of secondary metabolites
kar01230
Biosynthesis of amino acids
Module
kar_M00024
Phenylalanine biosynthesis, chorismate => phenylpyruvate => phenylalanine
kar_M00025
Tyrosine biosynthesis, chorismate => HPP => tyrosine
Brite
KEGG Orthology (KO) [BR:
kar00001
]
09100 Metabolism
09105 Amino acid metabolism
00400 Phenylalanine, tyrosine and tryptophan biosynthesis
LGL98_06035 (tyrA)
09110 Biosynthesis of other secondary metabolites
00401 Novobiocin biosynthesis
LGL98_06035 (tyrA)
Enzymes [BR:
kar01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.12 prephenate dehydrogenase
LGL98_06035 (tyrA)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.5 chorismate mutase
LGL98_06035 (tyrA)
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Motif
Pfam:
CM_2
PDH_C
PDH_N
F420_oxidored
NmrA
RS_preATP-grasp-like
DUF3151
SDR
Motif
Other DBs
NCBI-ProteinID:
UDD41498
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Position
1227559..1228680
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AA seq
373 aa
AA seq
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MVAELTALRDQIDEVDKALLSLLAKRLELVAEVGEVKSQYGLPIYVPEREAAMLASRREE
AAALGVPPDLIEDVLRRVMRESYSSENDKGFKTLQPNLRPVVIVGGGGQMGRLFEKMLML
SGYQVRILEKDDWARAAEIVADAGMVIVSVPIHTTVETIGRLPPLPADCILVDLASVKAE
PLQAMLAAHQGPVLGLHPMFGPDSGSLAKQVVVYCDGRQPEAYQWFLEQIQVWGARLHRI
SAVEHDQNMAFIQALRHFATFAYGLHLAEENVRLEQLLALSSPIYRLELAMVGRLFAQDP
QLYADIIMSSENNLALIKRYYQRFGEAIGLLEQGDKQAFIDSFRKVEHWFGDYAQRFQSE
SRTLLRQANDNRQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atggttgctgaactgaccgcgttacgcgatcaaattgatgaagtggataaagcgttgctt
agcctgctggctaagcgtctggaactggtggccgaagtcggcgaggtaaagagccagtat
ggcctgccgatttacgtcccggaacgcgaggcggcgatgcttgcctcccggcgtgaagag
gcggcagcgctcggcgtaccgccggatctgatcgaggatgttctgcgtcgcgtaatgcgg
gaatcctattccagcgaaaacgacaaaggcttcaaaaccctgcagccgaatctgcggccg
gtggtgatcgtcggcggcggcgggcagatgggacgtctgtttgagaagatgttaatgctg
tccggctaccaggtgcgtattctggaaaaagacgattgggcgcgggcggcggaaatcgtc
gccgatgccggcatggtcatcgtcagcgtaccgattcacaccaccgtggagacgattggc
aggctgccgcccctgccggcggattgcatcctggtcgatctcgcctcggtgaaagcggag
ccgctgcaggcgatgctggcggcgcatcagggcccggttcttggcctgcatccgatgttt
ggtccggacagcggcagcctggcgaaacaggtggtggtctattgcgatggccggcagccg
gaggcctatcagtggtttctcgaacaaattcaggtctggggagcgcggctgcatcgcatc
agcgccgtagagcacgaccagaatatggccttcattcaggcgctgcgccactttgccacc
tttgcctatgggctgcacctggcggaagagaatgtgcgtcttgagcaactgctggcgctt
tcgtcacctatttaccgtctggaactggcgatggtaggccgtctgtttgcccaggatccg
cagctatacgccgacattattatgtcatcggaaaacaacctggcgctgattaagcgctat
taccagcgttttggcgaagcgattggcctgctggagcagggcgataagcaggcgtttatc
gacagcttccgtaaagttgaacactggtttggcgattacgcccagcgtttccagagcgag
agccgcacgctactgcgtcaggcgaatgataatcggcagtaa
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