KEGG   Kitasatospora aureofaciens: B6264_21000
Entry
B6264_21000       CDS       T05021                                 
Name
(GenBank) methionine synthase
  KO
K00548  5-methyltetrahydrofolate--homocysteine methyltransferase [EC:2.1.1.13]
Organism
kau  Kitasatospora aureofaciens
Pathway
kau00270  Cysteine and methionine metabolism
kau00450  Selenocompound metabolism
kau00670  One carbon pool by folate
kau01100  Metabolic pathways
kau01110  Biosynthesis of secondary metabolites
kau01230  Biosynthesis of amino acids
kau04980  Cobalamin transport and metabolism
kau04981  Folate transport and metabolism
Module
kau_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:kau00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    B6264_21000
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    B6264_21000
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    B6264_21000
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    B6264_21000
   04980 Cobalamin transport and metabolism
    B6264_21000
Enzymes [BR:kau01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     B6264_21000
SSDB
Motif
Pfam: S-methyl_trans Pterin_bind Met_synt_B12 B12-binding_2 B12-binding CdhD
Other DBs
NCBI-ProteinID: ARF81051
UniProt: A0A1E7N566
LinkDB
Position
4732258..4735767
AA seq 1169 aa
MATAADPSITQQSRANALREALATRVVVADGAMGTMLQAQDPTLEDFQDLEGCNEVLNIT
RPDIVRSVHEAYFAVGVDCVETNTFGANFAALGEYDISERIFELSEAGARIAREVADAHA
ADGRTRWVLGSIGPGTKLPTLGHAPYETLRDGFQQNAAGLIAGGADALLVETSQDLLQTK
AAILGSKRALAEAGLDLPVLVQVTVETTGTMLLGSEIGAALTALEPLGVDFIGLNCATGP
AEMSEHLRYLAKNARIGLSCMPNAGLPVLGKDGAHYPLSPAELAEAHDVFTREYGLSLVG
GCCGTTPEHLRQVVEKVQGRPIARRDPQPEPSAASLYQAVPFRQDTSYLAIGERTNANGS
KKFRESMLAGDWQACVEIARDQIRDGSHLLDLCVDYVGRDGVADMKEIAGRLATASTLPI
VLDSTEPPVLQAGLEALGGRAVLNSVNYEDGNAPDSRFGRIASLAREHGAGLIALTIDEQ
GQARTAEKKVEIAERLIAELTSDYGIDEGSILVDCLTFTLATGQEESRRDGIETIEAIRE
LKRRHPGVQTTLGLSNISFGLNPAARVVLNSVFLHECVEAGLDSAIVHASKILPISRIPE
DQREAALDLVYDRRRDGYDPLQRLLELFENVSTASVKASKAQELAALPLEERLQRRIIDG
ERGGLEADLDEALGERPALEIINDTLLSGMKVVGELFGSGQMQLPFVLQSAEVMKTAVAH
LEPHMEKSESEGKGTIVLATVKGDVHDIGKNLVDIILSNNGYNVVNLGIKQPVSAILDAA
QEHNADVIGMSGLLVKSTVIMKENLEELNQRKLAASYPVILGGAALTRAYVEQDLHEIYE
GEVRYARDAFEGLRLMDALIAVKRGVPGATLPELKQRRHARVEVEEPEPEVNLGQIRSDV
ALDNALPTPPFWGDRIVKGIPFADYASWLDEDALFKGQWGLKAARNGDGPSYEELVETEG
RPRLRAWLDRLQTEGWLEAAVVYGYYPANSKGDDLIVFHEDGTERTRFTFPRQRRGRRLC
LADFFRPEESGERDVVGLQVVTMGNRISEAANELFAGNSYRDYLELHGLSVQLAEALAEF
WHARVRYELGFSGEDPQDVKDMFALKYRGARFSLGYGACPELEDRAKIAELLKPERIGVV
LSEEFQLHPEQSTDAIVIHHPEAKYFNAR
NT seq 3510 nt   +upstreamnt  +downstreamnt
atggccactgcagccgacccgtccatcactcagcagagccgcgcgaacgcgctgcgcgaa
gcactcgccacccgggtggtggtcgccgacggtgcgatgggcaccatgctccaggcgcag
gacccgacgctggaggacttccaggacctcgagggctgcaacgaggtcctcaacatcacc
cggccggacatcgtccgctccgtgcacgaggcctacttcgcggtgggcgtggactgcgtc
gagaccaacaccttcggcgccaacttcgccgcgctgggcgagtacgacatctccgagcgg
atcttcgagctctccgaggccggcgcccggatcgcccgcgaggtggccgacgcccacgcc
gccgacggccgcacccgctgggtgctcggctcgatcggccccggcaccaagctgccgacc
ctcggccacgccccgtacgagacgctgcgcgacggcttccagcagaacgcggccggcctg
atcgccggtggcgccgacgcgctgctggtggagaccagccaggacctgctgcagaccaag
gccgcgatcctgggctccaagcgcgccctggccgaggccgggctggacctcccggtgctg
gtgcaggtgacggtggagaccaccggcaccatgctgctcggctccgagatcggcgccgcg
ctcaccgcgctggagccgctcggcgtcgacttcatcggcctcaactgcgccaccggcccg
gccgagatgagcgagcacctgcgctacctggccaagaacgcgaggatcggcctgtcctgc
atgccgaacgcgggcctgccggtgctcggcaaggacggtgcccactacccgctctccccg
gccgaactggccgaggcgcacgacgtgttcacccgcgagtacgggctctcgctggtcggc
ggctgctgcggcaccacgcccgagcacctgcgccaggtggtggagaaggtccagggccgc
ccgatcgcccggcgcgatccccagccggagccctcggccgcctcgctctaccaggcggtg
ccgttccgccaggacacctcgtacctggcgatcggcgagcgcaccaacgccaacggctcg
aagaagttccgcgagtcgatgctggccggcgactggcaggcctgcgtggagatcgcccgg
gaccagatccgggacggctcgcacctgctggacctgtgcgtggactacgtcggccgcgac
ggcgtcgccgacatgaaggagatcgccggccggctggccaccgcctccaccctgccgatc
gtgctggactccaccgagccgccggtgctgcaggccggcctggaggcgctcggcggccgc
gcggtgctcaactcggtcaactacgaggacggcaacgcccccgactcgcgcttcggccgg
atcgcgtcgctggcccgcgagcacggcgccggcctgatcgcgctgaccatcgacgagcag
ggccaggcccgtacggccgagaagaaggtggagatcgccgagcggctgatcgccgagctg
acctccgactacggcatcgacgagggctcgatcctggtcgactgcctcaccttcaccctg
gccaccggccaggaggagtcccgccgggacggcatcgagacgatcgaggcgatccgcgag
ctcaagcgccgccacccgggggtgcagaccaccctcggcctgtcgaacatctccttcggc
ctcaacccggccgcccgcgtggtgctcaactcggtcttcctgcacgagtgcgtggaggcc
ggcctggactcggcgatcgtgcacgcctccaagatcctgccgatctcccggatccccgag
gaccagcgcgaggccgccctcgacctggtgtacgaccgccgccgggacggctacgacccg
ctgcagcgcctgctggagctgttcgagaacgtctccaccgcctcggtcaaggcctccaag
gcgcaggagctggccgcgctcccgctggaggagaggctgcagcgccggatcatcgacggc
gagcggggcggcctggaggccgacctggacgaggccctgggcgagcgccccgcgctggag
atcatcaacgacacgctgctgtccggcatgaaggtggtcggcgagctcttcggctccggc
cagatgcagctgccgttcgtgctccagtccgccgaggtgatgaagaccgcggtggcccac
ctggagccgcacatggagaagtccgagagcgagggcaagggcaccatcgtgctggccacc
gtcaagggcgacgtccacgacatcggcaagaacctggtcgacatcatcctgtccaacaac
ggctacaacgtggtcaacctgggcatcaagcagccggtctcggcgatcctggacgccgcg
caggagcacaacgcggacgtcatcggcatgtcaggcctgctggtgaagtccaccgtgatc
atgaaggagaacctggaggagctgaaccagcgcaagctggccgccagctacccggtgatc
ctcggcggcgccgccctgacccgcgcctacgtcgagcaggacctgcacgagatctacgag
ggcgaggtccgctacgcccgggacgccttcgagggcctgcggctgatggacgccctgatc
gcggtcaagcgcggcgtgcccggcgcgaccctgccggagctcaagcagcgtcggcacgcc
cgggtcgaggtggaggagccggagcccgaggtcaacctcggccagatccgctccgacgtg
gcgctggacaacgcgctgcccaccccgccgttctggggcgaccggatcgtcaagggcatc
ccgttcgccgactacgcctcctggctggacgaggacgcgctgttcaagggccagtggggc
ctgaaggccgcacgcaacggcgacggcccgtcctacgaggagctggtggagaccgagggc
cggccgcggctgcgggcctggctggaccggctgcagaccgagggctggctggaggcggcc
gtggtctacggctactacccggccaactccaagggcgacgacctgatcgtcttccacgag
gacggcaccgagcggacccgcttcaccttcccccgccagcggcgcggccgccggctctgc
ctggcggacttcttccgcccggaggagtccggcgagcgggacgtggtcggcctgcaggtg
gtcaccatgggcaaccggatctccgaggcggccaacgagctgttcgccgggaactcctac
cgcgactacctggagctgcacggcctgtcggtgcagctggccgaggcgctcgccgagttc
tggcacgcccgggtccgctacgagctgggcttctccggcgaggacccgcaggacgtcaag
gacatgttcgcgctcaagtaccggggcgcccgcttctcgctcggctacggagcctgcccc
gagctggaggaccgcgccaagatcgccgagctgctgaagcccgagcggatcggcgtggtg
ctctccgaggagttccagctgcacccggagcagtccaccgacgcgatcgtgatccaccac
ccggaggcgaagtacttcaacgcccggtaa

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