KEGG   Candidatus Kaiserbacteria bacterium NC_groundwater_79_Ag_B-0.1um_58_26: HYS26_01590
Entry
HYS26_01590       CDS       T09896                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
kbn  Candidatus Kaiserbacteria bacterium NC_groundwater_79_Ag_B-0.1um_58_26
Pathway
kbn03030  DNA replication
kbn03410  Base excision repair
kbn03420  Nucleotide excision repair
kbn03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:kbn00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    HYS26_01590 (ligA)
   03410 Base excision repair
    HYS26_01590 (ligA)
   03420 Nucleotide excision repair
    HYS26_01590 (ligA)
   03430 Mismatch repair
    HYS26_01590 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:kbn03032]
    HYS26_01590 (ligA)
   03400 DNA repair and recombination proteins [BR:kbn03400]
    HYS26_01590 (ligA)
Enzymes [BR:kbn01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     HYS26_01590 (ligA)
DNA replication proteins [BR:kbn03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     HYS26_01590 (ligA)
DNA repair and recombination proteins [BR:kbn03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     HYS26_01590 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     HYS26_01590 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     HYS26_01590 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      HYS26_01590 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 PTCB-BRCT HHH HHH_3 DNA_ligase_ZBD HHH_8 Nlig-Ia 5_3_exonuc
Other DBs
NCBI-ProteinID: QQG38229
UniProt: A0A7T5R6B3
LinkDB
Position
275422..277440
AA seq 672 aa
MSEIPAETRGRYEKLKSTINRYRTLYHVYDKEGISQAALDSLKHELTEIETRYPKIIAPD
SPSQRVAGKPLPQFKKVRHSVPQWSFNDAFTEEEIREFDARTKRFLRAKFGDTAPTYVCE
LKIDGLKVVLTYEKGLLKTAATRGDGVVGEDVTHNIKTIESVPLSLPRQIDAVVEGEVWM
SAASLETLNRVRRKAGQPLFANPRNAAAGSIRQLDPKIAAERNLDVFIYDVAQSSEKIPQ
TQEEELVYLQELGFKVNHHKKTFKTVDGVIDFWNEWQKKGRHQQYWVDGIVVKVNERDFQ
EALGYTGKAPRFAIAFKFPAEQVTTVLEDIVLQVGRTGVLTPVAHLKPVQVAGTIVSRAT
LHNEDEITRLDVRVGDTVILQKAGDVIPDIVQVVKELRPKGAKPYAWPTHVPECGGDGRI
ERVPGTAAWRCVNKNSFAVIRRRFHNFVGKHALDIEGLGKERVDQLLEEGLVQHYDEIFS
LKEGDLLRLEGYAPVSAKKLVDAIQKARSVDLARLLTGLSIPQVGEETATLLAKHYRTID
EIAKASAEDLEHIEGVGPIVAREITEWFALKRHHTLLKNLKDVLTISNTLHAHKSAGKLS
GKTYVLTGTLSSMSRDEAKEKLRLLGADVSGSVSKKTTAVIAGENAGSKLDKAKELGVPV
LTEEAFVRMIGR
NT seq 2019 nt   +upstreamnt  +downstreamnt
atgtcagagattccggccgagactcgcgggcgctacgagaaactgaagtcgacgatcaac
cgctaccgtaccctctaccacgtctacgataaagaggggatttcgcaggctgcgctggat
tccctgaagcacgagctcacggagattgagacgcggtatccaaaaataatcgcgcccgat
tctccctcgcagcgggtggccgggaagcccttgccgcaattcaagaaggttcggcacagc
gtgccgcagtggtcgttcaacgacgcctttaccgaggaagagatacgggagttcgacgcg
cgcacgaaacgattcctccgggcgaaatttggcgacacggcaccgacgtacgtgtgcgag
ctgaaaatcgacggcctcaaggtggtgctcacgtacgaaaagggtcttttgaaaacagcg
gcgacccgcggcgacggagtcgtgggggaggacgtgacgcacaacataaagacgatcgaa
tccgtgccgctctcactgccgaggcagatcgatgcggtggtggagggcgaggtgtggatg
agcgcggcatcgctcgaaacactgaatcgcgtgcgaagaaaggcggggcagccgctcttt
gcgaatccgcgcaacgcggcggccggctcgatccggcagctcgatccgaaaattgctgcc
gagcgtaatctcgatgttttcatctacgacgtcgcccaaagttcggagaagataccgcag
acgcaggaagaagagctcgtttacttgcaggagcttggcttcaaagtgaatcaccacaaa
aaaacctttaaaacggtcgacggcgtgatcgacttttggaatgagtggcaaaaaaagggg
cggcaccagcagtattgggtcgacgggatcgtcgtgaaggtcaacgagcgtgatttccag
gaagcgctcgggtacaccggaaaagccccgcgttttgcgatcgctttcaagtttccggcg
gagcaggtgaccaccgtgctcgaagacatcgtgctccaggtggggcgcacgggcgtcctc
acgccggtcgcgcacttgaaaccggtgcaggtggccgggacgatcgtgagccgtgccacg
ctgcacaacgaagatgagatcacgcggctcgacgtgcgtgtcggcgatacggtgattttg
cagaaggcgggtgatgtgattcccgacatcgtgcaggttgtgaaggagttgcgccccaag
ggcgcaaagccttacgcgtggcccacacacgtgccggagtgcggcggcgacggccgcatc
gagcgcgtccccggcaccgccgcgtggcgctgcgtcaataaaaattcgtttgcggtgatt
cgccgccgcttccacaattttgtggggaagcacgcactcgacatcgaagggctcgggaaa
gagcgggtcgatcagctgctcgaagaggggctggtgcagcactatgacgaaatcttttcg
ctgaaggaaggcgatctcttgcggctcgaagggtatgctccggtctcggccaaaaagctt
gtcgacgcgattcaaaaagcgcgcagcgtggatctcgcgcgcctccttaccggtctttcg
ataccgcaggtgggggaggaaacggcgactctgctcgcgaagcactaccgcacgatcgac
gagatcgcgaaagcctctgccgaggatctcgaacacatagaaggagtcgggccgatcgtc
gcccgcgagattaccgagtggtttgcgctgaagcggcatcacacgctcctgaagaatctg
aaagacgtccttaccatttccaacacactgcacgcacacaagtccgcagggaaactgtcc
ggcaaaacgtacgtactcaccggcactcttagctcgatgtcgcgcgatgaggccaaggag
aagctgcgcctcctcggggccgatgtctccgggtcggtctccaaaaaaacgaccgcagtc
atcgcaggcgaaaacgccggctccaagcttgataaagcaaaggagctgggagtccctgtg
ctgacagaggaagcgtttgtgcgtatgataggccgatga

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