KEGG   Ktedonosporobacter rubrisoli: EPA93_00395
Entry
EPA93_00395       CDS       T05969                                 
Name
(GenBank) bifunctional homocysteine S-methyltransferase/methylenetetrahydrofolate reductase
  KO
K24042  methionine synthase / methylenetetrahydrofolate reductase (NADH) [EC:2.1.1.13 1.5.1.54]
Organism
kbs  Ktedonosporobacter rubrisoli
Pathway
kbs00270  Cysteine and methionine metabolism
kbs00450  Selenocompound metabolism
kbs00670  One carbon pool by folate
kbs01100  Metabolic pathways
kbs01110  Biosynthesis of secondary metabolites
kbs01120  Microbial metabolism in diverse environments
kbs01230  Biosynthesis of amino acids
Module
kbs_M00017  Methionine biosynthesis, aspartate => homoserine => methionine
Brite
KEGG Orthology (KO) [BR:kbs00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00270 Cysteine and methionine metabolism
    EPA93_00395
  09106 Metabolism of other amino acids
   00450 Selenocompound metabolism
    EPA93_00395
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    EPA93_00395
Enzymes [BR:kbs01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.54  methylenetetrahydrofolate reductase (NADH)
     EPA93_00395
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.13  methionine synthase
     EPA93_00395
SSDB
Motif
Pfam: S-methyl_trans MTHFR
Other DBs
NCBI-ProteinID: QBD74533
UniProt: A0A4P6JHW7
LinkDB
Position
complement(75139..77055)
AA seq 638 aa
MNTTSPFLTHLRHGPLLCDGGMGTELHARGVPYEHCFEQLNLSSPELIKGIHLDYIAAGA
QIIETNTFGANRYRLAEHGLAHAVREINRAGAKIAREARELSDLPIFLAGNIGPLGSPLA
PLGSIKETEAYAAFLEQAEALLQAGVDLFLLETFSDITEMRAALSAVRNITDLPIVALMT
FTDDGRVASGEDPQVVARTLQEQGADIVGVNCALGPSSMFDVVAAMCHTTSEQLFIAAQP
NAGLPKRVGNRFMYIATPDYFATYARRFLDLGVRLIGGCCGTTPQHIAAMRKVLDESVPQ
EGRAQNVKIEPVPEALQEHKVHPPENDPGIVQTTHLADLLLKENFVVSVEMRPPRSVKYT
RFLQNAALLRDGGADIINIPDNAMARVRMNNIAAARLIQQYVGLETIVHFTPRDRNLMAV
QSDVIGAHATGIRNILAITGDPPGHGDFPHATGIWDVDSIGLIAMMHNLNQGLDAKGRRL
AAQSSFYIGCAANPTATDVALDLERLQQKIESGAMYVMTQPIFDANALLDYLEQYTQRYG
ALRMPLIVGLQPLHSYQQAEKFHNEVPGIVIPDHIRARLYQAGEAASRVGIEQTMEVFDA
LAPIVQGVYIMPLDRFELIHELLPYIRSRKAACAKSTV
NT seq 1917 nt   +upstreamnt  +downstreamnt
atgaatacgacgagtccattcctaacccatctacggcacggtcctcttctctgtgacggt
ggaatgggaacagagctgcacgcgcggggtgtgccttatgagcattgctttgaacaactc
aatctcagctcccccgaattgattaagggcatccaccttgattacatcgcagccggggca
cagatcatcgagaccaacacttttggcgcaaatcgctatcggctcgccgaacatgggctg
gcacacgcagtgcgcgaaatcaatcgggctggagcaaaaatagctcgtgaagcgcgcgaa
ctcagcgatttgcccatattcctggccggcaatattggtcccctgggcagtcctttagca
ccacttgggagtatcaaagaaactgaggcttatgccgctttccttgaacaggccgaagct
cttttgcaagctggcgttgatctcttcctgctggaaactttctcagatattacggaaatg
cgcgcagcattaagcgccgtgcgcaatataacggacctacccatagtcgccttgatgact
tttaccgatgatgggcgcgtagccagcggcgaagatccccaggtagtggcaaggaccctg
caggagcaaggcgcagacattgtaggcgttaactgcgcgctggggccgtccagcatgttc
gatgttgtcgccgcaatgtgccatacgactagtgagcaattatttatcgcagctcagccc
aatgccggcctccctaaacgcgtgggcaatcgctttatgtacattgccactcccgattac
tttgcgacatatgctcggcgctttctggatcttggcgtgcgcttgattggtggctgttgt
gggacaactcctcagcatatcgccgcgatgcgcaaggtgcttgatgagtccgtgccacaa
gagggacgggcacagaatgtgaagattgagcctgttcccgaagcactgcaagaacacaaa
gtccatcctcctgagaacgatcccggcatagttcagactacccacctggcggacttgctg
ctgaaggaaaattttgtagtcagcgtagaaatgaggccaccacgcagcgtcaaatacacg
cgctttctgcaaaatgctgctctgctgcgcgatgggggcgcagacattattaatatccct
gataatgctatggctcgcgtgcggatgaacaacattgcagcagcccgcttgattcaacaa
tatgttgggctagagaccattgtccactttacaccacgcgaccgcaaccttatggccgtg
cagagcgatgttattggcgctcacgcgacaggtatacgcaatatcctggcgattactggt
gatccgcccggacatggagattttccgcatgcgacaggcatttgggatgttgacagtatc
gggctcattgccatgatgcacaatttaaatcagggcctggatgccaaaggacgcaggctg
gcagctcagagctcattctatattggctgtgccgctaatccgaccgcaactgatgtagcc
ctggatcttgaacggctccaacagaagattgaaagcggagcaatgtatgtgatgacgcag
ccgatattcgatgcaaacgccttgcttgactaccttgagcaatatacacaacgctatgga
gccctacgcatgccacttattgtgggtctgcagccgctacattcgtatcagcaggctgaa
aagttccataatgaggtgcctggaatagttattccagaccatattcgggcgcgtttatat
caggcaggagaagcagcgagtagagttggtatagagcagaccatggaagtctttgacgct
ctggcgcctattgttcaaggcgtctatattatgccgcttgatcgtttcgaattgatacac
gagctgcttccctatattcgcagccgaaaagccgcctgcgctaagtccacagtttga

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