Streptomyces sp. NL15-2K: Q4V64_47120
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Entry
Q4V64_47120 CDS
T09250
Symbol
shc
Name
(GenBank) squalene--hopene cyclase
KO
K06045
squalene-hopene/tetraprenyl-beta-curcumene cyclase [EC:
5.4.99.17
4.2.1.129
]
Organism
kbu
Streptomyces sp. NL15-2K
Pathway
kbu00909
Sesquiterpenoid and triterpenoid biosynthesis
kbu01110
Biosynthesis of secondary metabolites
Brite
KEGG Orthology (KO) [BR:
kbu00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
00909 Sesquiterpenoid and triterpenoid biosynthesis
Q4V64_47120 (shc)
Enzymes [BR:
kbu01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.129 squalene---hopanol cyclase
Q4V64_47120 (shc)
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.17 squalene---hopene cyclase
Q4V64_47120 (shc)
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
TED_complement
Prenyltrans
Motif
Other DBs
NCBI-ProteinID:
WKX14674
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All DBs
Position
10782045..10784033
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AA seq
662 aa
AA seq
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MTATTDGSTGALPPRAAAASESDSTPVAAGVHDAAVRAVKRATDFLLARQDAQGWWKGDL
ETNVTMDAEDLLLRQFLGIRDEKTTQAAALFIRGEQREDGPWATFYGGPGELSATIEAYV
ALRLAGDAPDAPHMAKASAWIRGQGGIAASRVFTRIWLALFGWWKWEDLPELPPELIYFP
TWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFPLDELHTDPNRPNPPKPLAPVASWD
GALQRLDKALHALRKVAPRKLRGAAMNSAARWIIERQENDGCWGGIQPPAVYSVIALHLL
GYDLEHPVMRAGLQSLDRFAVWREDGARMIEACQSPVWDTCLAAIALADAGVPADHPQLV
RAADWMLGEQIVRPGDWSVRRPQLPPGGWAFEFHNDNYPDIDDTAEVVLALRRIKHHAPE
RVEKAIGRGVRWNLGMQSKNGAWGAFDVDNTSPFPNRLPFCDFGEVIDPPSADVTAHVVE
MLAVEGLSHDPRTRRGIEWLLAEQEPDGSWFGRWGVNYVYGTGSVVPALTAAGIPGSHPA
IRRAVAWLESVQNDDGGWGEDLRSYKYVKEWSGRGASTASQTAWALMALLAAGEKDSPAV
ERGIEWLASTQREDGSWDEPYFTGTGFPWDFSINYHLYRQVFPLTALGRYVHGEPFSGAK
GG
NT seq
1989 nt
NT seq
+upstream
nt +downstream
nt
atgacagcgacgaccgacggaagcaccggggccctgccgccccgcgctgccgcggccagc
gaatccgacagcacacccgtggcggccggggtgcacgacgccgccgtacgcgccgtgaag
cgcgccaccgacttcctgctggcgaggcaggatgcccaaggctggtggaagggcgacctc
gagaccaacgtcacgatggacgccgaggacctgctgctgcgtcagttcctgggtatccgc
gacgagaagaccacacaggccgccgccctcttcatccgcggcgagcagcgcgaggacggc
ccctgggccaccttctacggcgggccgggcgaactctccgccaccatcgaggcctacgtc
gcgctccgcctggccggcgacgccccggacgcgccgcacatggcgaaggcatccgcctgg
atccgtgggcagggcgggatcgccgcctcccgtgtgttcacccggatctggctggctctg
ttcggctggtggaagtgggaggacctgcccgaactcccgccggagctcatctacttcccg
acatgggtgccgctcaacatctacgacttcgggtgctgggcccggcagaccatcgtcccg
ttgacgatcgtctccgccaaacgaccggtgcggcccgcgcccttcccgctcgacgaactg
cacactgatccgaaccggccgaacccgcccaagcccctcgcgcccgtggcgagttgggac
ggcgccttacagcgtctggacaaggccctgcacgcgctgcgcaaggtcgcgccgcgcaag
ctgcgcggagccgcgatgaacagcgccgcccgctggatcatcgagcgccaggagaacgac
ggctgctggggaggcatccagccgccggccgtgtactcggtcatcgccctgcatctgctc
ggctacgacctcgagcatcccgtgatgcgtgcgggccttcagtcgctggaccgtttcgcc
gtgtggcgcgaggacggggcccggatgatcgaggcctgtcagtcgccggtctgggacacc
tgcctggcggccatcgcgctcgccgacgcgggggtgcccgccgaccatccccaactggtc
agggccgccgactggatgctcggcgagcagatcgtgcggcccggcgactggtcggtccgc
agaccccaactgccgcccggcggctgggcgttcgagttccacaacgacaactaccccgac
atcgacgacaccgccgaggtcgtcctcgcgctgcgccggatcaagcaccacgccccggag
cgggtggagaaggcgatcgggcgcggggtgcgctggaacctcggcatgcagtccaagaac
ggggcgtggggcgccttcgacgtcgacaacaccagcccgttccccaaccggctgccgttc
tgcgacttcggcgaggtcatcgacccgccgtcggcggacgtcaccgcgcacgtcgtcgag
atgctcgcggtggagggcctctcgcacgacccgcgcaccaggcgcggcatcgagtggctg
ctcgccgaacaggagccggacggctcgtggttcggacgctggggcgtcaactacgtctac
ggcaccggatccgtcgtacccgccctgaccgccgccgggatccccggctcgcaccccgcg
atccggcgggccgtggcctggctggagtcggtgcagaacgacgacggcggctggggcgag
gatctgcgctcctacaagtacgtcaaggaatggagcggccggggcgcctcgaccgcctcg
cagacggcctgggcgctgatggccctgctggccgcgggggagaaggactccccggccgtc
gagcgcggcatcgagtggctcgcgagcacccagcgggaggacggctcctgggacgagccg
tacttcaccggcaccggcttcccgtgggacttctccatcaactaccacctctaccggcag
gtcttcccgctcaccgccctcggccggtacgtccacggagagccgttctccggggccaag
gggggctga
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