KEGG   Klebsiella sp. MPUS7: GUC22_06995
Entry
GUC22_06995       CDS       T10508                                 
Symbol
ligA
Name
(GenBank) NAD-dependent DNA ligase LigA
  KO
K01972  DNA ligase (NAD+) [EC:6.5.1.2]
Organism
klp  Klebsiella sp. MPUS7
Pathway
klp03030  DNA replication
klp03410  Base excision repair
klp03420  Nucleotide excision repair
klp03430  Mismatch repair
Brite
KEGG Orthology (KO) [BR:klp00001]
 09120 Genetic Information Processing
  09124 Replication and repair
   03030 DNA replication
    GUC22_06995 (ligA)
   03410 Base excision repair
    GUC22_06995 (ligA)
   03420 Nucleotide excision repair
    GUC22_06995 (ligA)
   03430 Mismatch repair
    GUC22_06995 (ligA)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03032 DNA replication proteins [BR:klp03032]
    GUC22_06995 (ligA)
   03400 DNA repair and recombination proteins [BR:klp03400]
    GUC22_06995 (ligA)
Enzymes [BR:klp01000]
 6. Ligases
  6.5  Forming phosphoric-ester bonds
   6.5.1  Ligases that form phosphoric-ester bonds (only sub-subclass identified to date)
    6.5.1.2  DNA ligase (NAD+)
     GUC22_06995 (ligA)
DNA replication proteins [BR:klp03032]
 Prokaryotic type
  DNA Replication Elongation Factors
   Elongation factors (bacterial)
    Other elongation factors
     GUC22_06995 (ligA)
DNA repair and recombination proteins [BR:klp03400]
 Prokaryotic type
  SSBR (single strand breaks repair)
   BER (base exicision repair)
    DNA ligase
     GUC22_06995 (ligA)
   NER (nucleotide excision repair)
    GGR (global genome repair) factors
     GUC22_06995 (ligA)
   MMR (mismatch excision repair)
    DNA ligase
     GUC22_06995 (ligA)
  DSBR (double strand breaks repair)
   NHEJ (non-homologous end-joining)
    SHDIR (short-homology-dependent illegitimate recombination)
     RecET pathway
      GUC22_06995 (ligA)
SSDB
Motif
Pfam: DNA_ligase_aden DNA_ligase_OB HHH_2 BRCT HHH_5 Nlig-Ia DNA_ligase_ZBD PTCB-BRCT HHH Prok-E2_C DZR_2
Other DBs
NCBI-ProteinID: QHI86672
LinkDB
Position
1464564..1466588
AA seq 674 aa
MESNEQKLTELRTTLRHHEYLYHVMDTPEIPDAEYDRLMRELRELEAQHPELITPDSPTQ
RVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRLKNTDDLTYCCELKLDGLA
VSILYENGLLVQAATRGDGTTGEDITSNVRTIRAIPLKLRGDNIPQRLEVRGEVFLPQAG
FEKINEEARRTGGKVFANPRNAAAGSLRQLDPRITAKRPLTFFCYGVGVLEGGELPRSHS
ARLQQFKFWGLPVSERVKLCHSPEEVLTYYRKVEEDRPNLGFDIDGVVIKVDSLALQEQL
GFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRTGAITPVARLEPVQVAGVLVSNATLHN
ADEIERLGLRIGDKVVIRRAGDVIPQVVNVVLSERPEETREIVFPTHCPVCHSDVERVEG
EVVTRCTGGLICGAQRKEALKHFVSRRALDVEGMGDKIIDQLVEKEYVHTPADLFQLTPG
KLTGLDRMGPKSAQNVVDALEKSKETTFARFLYALGIREVGEATAAGLAAHFGTIEALEQ
ASIDDLQKVPDVGIVVATHVRNFFAEESNREVIAQLRKEGVRWPAPVVVNAEEIDSPFAG
KTVVLTGSLSQLSRDDAKARLVALGAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIAVI
DEDEMLRLLGESRG
NT seq 2025 nt   +upstreamnt  +downstreamnt
atggaatcgaacgaacaaaaactgactgaactgcgaaccacgcttcgccatcatgaatac
ctgtaccacgtcatggatacgccggaaattcctgatgctgaatacgatcggctgatgcgt
gaactacgtgaactggaagctcaacatcctgaattgattacgcccgattcacctacccag
cgcgtcggcgccgcaccgctagccgcattcagccagattcgccatgaagtgccgatgttg
tcgctggataacgttttcgatgaagagagcttccttgcgtttaataagcgcgttcaggat
cggttgaaaaataccgatgatctgacctactgctgtgagctcaagctggatggcctggcg
gtcagtatcctgtatgaaaacggcttgctggtacaggcggcgacccgcggcgatggaacg
accggtgaagatatcacctccaacgtacgcaccattcgcgctatccctctgaagcttcgc
ggcgacaatattccgcagcggcttgaggttcgtggagaggttttcctgccgcaggcgggg
ttcgaaaaaatcaatgaagaggcgcggcgaaccggcgggaaggtatttgctaacccgcga
aacgccgctgcaggttctttacgccagctcgatccgcggattaccgcgaagcgtccactc
actttcttttgctacggcgtgggcgtgctggaaggcggcgagctgccgcgaagccactca
gcgcgcttgcagcagtttaagttctgggggctgccggtcagcgagcgcgtaaagctctgc
cattctccagaggaagtgcttacttactatcgcaaggttgaagaagatcggccgaatctg
gggtttgatattgacggtgtggttatcaaagtggattcgcttgcgcttcaggaacagctt
ggcttcgtggcccgcgcgccgcgctgggcggtggcgtttaagtttccggcccaggagcag
atgactttcgtgcgcgatgtcgagtttcaggtcgggcgtaccggcgccatcacgccggta
gcgcgtctggagccggtacaggtcgccggcgtcctggtcagcaacgcgacgctgcataat
gctgatgaaatcgagcgtctggggctgcgcatcggcgataaggtggttattcgccgcgcc
ggtgatgttatccctcaggtcgtgaacgtcgttctctcagaacgcccggaggagacgcgt
gaaatcgtgtttcccacccattgcccggtatgtcattccgacgttgaacgcgtagaaggc
gaagtggtgacccgctgtaccggcggtctgatctgcggcgcccagcgtaaagaagcgctc
aagcattttgtctcccgtcgcgccctggacgtggagggaatgggcgataaaatcatcgat
cagctggttgaaaaagagtacgtgcatacgcctgccgatctctttcaactgacgccgggt
aagcttaccgggctcgatcgcatggggccaaaatcagcgcaaaacgtggtggatgcgctg
gagaagtcaaaagagaccacctttgcccgtttcctttacgcgctggggatccgcgaagtg
ggtgaggcgacggcagccggtttagcggcccactttggcaccattgaggcgctggagcag
gcttcaattgacgatctgcaaaaagtgcccgatgtcgggattgtggtcgccacgcacgtg
cgtaatttctttgccgaagagagcaatcgcgaagtgattgctcagctgcgtaaagaaggc
gtccgctggccggcgccggtggtggtcaatgcggaagagatcgatagcccctttgccggg
aaaacggtggttctgaccggtagcctgagtcagctctcccgtgatgatgcgaaagcccgg
ctggttgcgctcggcgcgaaggtggcgggcagcgtgtcgaagaagaccgacctggttatc
gccggggaggcggcgggctctaagctcgccaaagcgcaggagctagggattgcggtgatc
gatgaagacgaaatgctgcgtctgctcggagagtcgcgtggataa

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